EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
RNA-binding motif protein, X-linked 2RBMX2 CGI-79Q9Y3885
RNA-binding protein 47 (RNA-binding motif protein 47)RBM47A0AV965
RPL5 protein (Ribosomal protein L5, isoform CRA_a)RPL5 hCG_2028912Q9BUV45
RUN domain-containing protein 1RUNDC1 LP5161Q96C345
RuvB-like helicase (EC 3.6.4.12)RUVBL2M0R0Y35
RuvB-like helicase (EC 3.6.4.12)RUVBL1E7ETR05
RuvB-like helicase (EC 3.6.4.12) (Fragment)RUVBL1J3QLR15
RWD domain-containing protein 1 (DRG family-regulatory protein 2)RWDD1 DFRP2 CGI-24 PTD013Q9H4465
Sarcosine dehydrogenase, mitochondrial (SarDH) (EC 1.5.8.3) (BPR-2)SARDH DMGDHL1Q9UL125
Scavenger receptor cysteine-rich type 1 protein M130 (Hemoglobin scavenger receptor) (CD antigen CD163) [Cleaved into: Soluble CD163 (sCD163)]CD163 M130Q86VB75
SecretagoginSCGN SECRETO760385
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)DVL2O146415
Semaphorin-3G (Semaphorin sem2)SEMA3GQ9NS985
Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100)SEMA4D C9orf164 CD100 SEMAJQ928545
Sentrin-specific protease 3 (EC 3.4.22.68) (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3)SENP3 SSP3 SUSP3Q9H4L45
Sentrin-specific protease 8 (EC 3.4.22.68) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)SENP8 DEN1 NEDP1 PRSC2 FKSG8Q96LD85
Sepiapterin reductase (Fragment)0Q930415
Septin-8SEPT8A0A087X1425
Serine protease inhibitor Kazal-type 1 (Pancreatic secretory trypsin inhibitor) (Tumor-associated trypsin inhibitor) (TATI)SPINK1 PSTIP009955
Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B)SRSF8 SFRS2B SRP46Q9BRL65
Serine/arginine-rich-splicing factor 11 (Fragment)SRSF11Q5T7605
Serine/arginine-rich-splicing factor 2 (Fragment)SRSF2J3QL055
Serine/arginine-rich-splicing factor 7SRSF7C9JAB25
Serine/threonine-protein kinase MARK1 (EC 2.7.11.1) (EC 2.7.11.26) (MAP/microtubule affinity-regulating kinase 1) (PAR1 homolog c) (Par-1c) (Par1c)MARK1 KIAA1477 MARKQ9P0L25
Serine/threonine-protein kinase Nek1 (EC 2.7.11.1) (Never in mitosis A-related kinase 1) (NimA-related protein kinase 1) (Renal carcinoma antigen NY-REN-55)NEK1 KIAA1901Q96PY65
Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)RIOK2Q9BVS45
Serine/threonine-protein phosphatase (EC 3.1.3.16)PPP1CCF8VYE85
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin, testis-specific catalytic subunit) (Calmodulin-dependent calcineurin A subunit gamma isoform)PPP3CC CALNA3 CNA3P484545
Serine/threonine-protein phosphatase 4 regulatory subunit 2PPP4R2 SBBI57Q9NY275
Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity phosphatase inhibitor MK-STYX) (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX)STYXL1 DUSP24 MKSTYXQ9Y6J85
Serpin B10 (Bomapin) (Peptidase inhibitor 10) (PI-10)SERPINB10 PI10P485955
Serpin I2 (Myoepithelium-derived serine protease inhibitor) (Pancpin) (Pancreas-specific protein TSA2004) (Peptidase inhibitor 14) (PI-14)SERPINI2 MEPI PI14O758305
Serrate RNA effector molecule homolog (Fragment)SRRTH7C3A15
Serum amyloid A protein0B2R5G85
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP)SHANK1Q9Y5665
SH3 domain and tetratricopeptide repeat-containing protein 1SH3TC1Q8TE825
SH3 domain-binding glutamic acid-rich-like protein 3SH3BGRL3Q5T1235
SH3KBP1-binding protein 1 (SETA-binding protein 1)SHKBP1 SB1 PP203Q8TBC35
Signal transducer and activator of transcriptionSTAT1J3KPM95
Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1)SIPA1L1 E6TP1 KIAA0440O431665
Signal-regulatory protein beta-1 (SIRP-beta-1) (CD172 antigen-like family member B) (CD antigen CD172b)SIRPB1O002415
Single-strand selective monofunctional uracil DNA glycosylase (EC 3.2.2.-)SMUG1Q53HV75
SLP adapter and CSK-interacting membrane protein (SLP65/SLP76, Csk-interacting membrane protein)SCIMP C17orf87 UNQ5783/PRO16090Q6UWF35
Small nuclear ribonucleoprotein Sm D1SNRPD1J3QLI95
Small ubiquitin-related modifier 4 (SUMO-4) (Small ubiquitin-like protein 4)SUMO4 SMT3H4Q6EEV65
SmoothelinSMTN SMSMOP538145
Sodium channel protein type 10 subunit alpha (Peripheral nerve sodium channel 3) (PN3) (hPN3) (Sodium channel protein type X subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.8)SCN10AQ9Y5Y95
Sodium-coupled neutral amino acid transporter 3 (N-system amino acid transporter 1) (Na(+)-coupled neutral amino acid transporter 3) (Solute carrier family 38 member 3) (System N amino acid transporter 1)SLC38A3 G17 NAT1 SN1 SNAT3Q996245
Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2)SLC6A2 NAT1 NET1 SLC6A5P239755
Sodium/potassium-transporting ATPase subunit beta-3 (Fragment)ATP1B3C9JA365
Solute carrier family 12 (Sodium/potassium/chloride transporters), member 2, isoform CRA_a (Solute carrier family 12 member 2)SLC12A2 hCG_27034G3XAL95
Solute carrier family 22 member 3 (Extraneuronal monoamine transporter) (EMT) (Organic cation transporter 3)SLC22A3 EMTH OCT3O757515
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2) (Sorbin)SORBS2 ARGBP2 KIAA0777O948755
Sorting nexin 17, isoform CRA_a (cDNA FLJ51047, highly similar to Sorting nexin-17) (cDNA FLJ53821, highly similar to Sorting nexin-17) (cDNA FLJ61770, highly similar to Sorting nexin-17)SNX17 hCG_1784432B4DDM35
Spectrin beta chainSPTBN1 hCG_17370D6W5C05
Sperm flagellar protein 2 (Protein KPL2)SPEF2 KIAA1770 KPL2Q9C0935
Spermatogenesis-defective protein 39 homolog (hSPE-39) (VPS33B-interacting protein in apical-basolateral polarity regulator) (VPS33B-interacting protein in polarity and apical restriction)VIPAS39 C14orf133 SPE39 VIPARQ9H9C15
Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III)SMPD4 KIAA1418Q9NXE45
Sphingosine 1-phosphate receptor 3 (S1P receptor 3) (S1P3) (Endothelial differentiation G-protein coupled receptor 3) (Sphingosine 1-phosphate receptor Edg-3) (S1P receptor Edg-3)S1PR3 EDG3Q995005
Splicing factor arginine/serine-rich 3 (Splicing factor, arginine/serine-rich 3, isoform CRA_d) (cDNA, FLJ92926, Homo sapiens splicing factor, arginine/serine-rich 3 (SFRS3), mRNA)SFRS3 hCG_14802B2R6F35
Splicing factor proline/glutamine-rich (Polypyrimidine tract binding protein associated)SFPQQ86VG25
Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)SFSWAP SFRS8 SWAPQ128725
SPOC domain-containing protein 1SPOCD1Q6ZMY35
Sprouty-related, EVH1 domain-containing protein 2 (Spred-2)SPRED2Q7Z6985
ST13 protein (Fragment)ST13Q0IJ565
Staufen isoform b variant (Fragment)0Q59F995
Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1)MMP3 STMY1P082545
Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2)MMP10 STMY2P092385
Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B)SMC1B SMC1L2Q8NDV35
Succinate receptor 1 (G-protein coupled receptor 91) (P2Y purinoceptor 1-like)SUCNR1 GPR91Q9BXA55
Sulfotransferase 1A3 (ST1A3) (EC 2.8.2.1) (Aryl sulfotransferase 1A3/1A4) (Catecholamine-sulfating phenol sulfotransferase) (HAST3) (M-PST) (Monoamine-sulfating phenol sulfotransferase) (Placental estrogen sulfotransferase) (Sulfotransferase 1A3/1A4) (Sulfotransferase, monoamine-preferring) (Thermolabile phenol sulfotransferase) (TL-PST)SULT1A3 STMP502245
Survival of motor neuron-related-splicing factor 30 (30 kDa splicing factor SMNrp) (SMN-related protein) (Survival motor neuron domain-containing protein 1)SMNDC1 SMNR SPF30O759405
Sushi, nidogen and EGF-like domain-containing protein 1 (Insulin-responsive sequence DNA-binding protein 1) (IRE-BP1)SNED1Q8TER05
Synapsin-2 (Synapsin II)SYN2Q927775
Synaptogyrin-3SYNGR3O437615
Synaptosomal-associated protein 23 (Fragment)SNAP23H3BR995
Synaptotagmin-13 (Synaptotagmin XIII) (SytXIII)SYT13 KIAA1427Q7L8C55
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Stimulator of TAR RNA-binding)CCT4 CCTD SRBB7Z8B15
T-complex protein 1 subunit theta (Fragment)CCT8H7C4C85
TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C)TAF1CQ155725
TBC1 domain family member 8 (AD 3) (Vascular Rab-GAP/TBC-containing protein)TBC1D8 VRPO957595
Tectonin beta-propeller repeat-containing protein 1TECPR1 KIAA1358Q7Z6L15
TELO2-interacting protein 2TTI2 C8orf41Q6NXR45
Tensin-4 (C-terminal tensin-like protein)TNS4 CTEN PP14434Q8IZW85
Testis-expressed protein 264 (Putative secreted protein Zsig11)TEX264 ZSIG11 UNQ337/PRO536Q9Y6I95
TetraspaninCD81E9PIF15
TetraspaninCD151E9PMR45
Tetratricopeptide repeat protein 12 (TPR repeat protein 12)TTC12Q9H8925
Tetratricopeptide repeat protein 30B (TPR repeat protein 30B)TTC30BQ8N4P25
TFIIH basal transcription factor complex helicase XPB subunit (EC 3.6.4.12) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)ERCC3 XPB XPBCP194475
TFIIH basal transcription factor complex helicase XPD subunit (EC 3.6.4.12) (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein)ERCC2 XPD XPDCP180745
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)TAB2 KIAA0733 MAP3K7IP2Q9NYJ85
Thiamine-triphosphatase (ThTPase) (EC 3.6.1.28)THTPAQ9BU025
Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP)TXN TRDX TRX TRX1B1ALW15
Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Selenoprotein Z) (SelZ) (TR-beta) (Thioredoxin reductase TR3)TXNRD2 KIAA1652 TRXR2Q9NNW75
Threonine--tRNA ligase, mitochondrial (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase-like 1)TARS2 TARSL1Q9BW925
Thrombospondin type-1 domain-containing protein 1 (Transmembrane molecule with thrombospondin module)THSD1 TMTSP UNQ3010/PRO9769Q9NS625
Thrombospondin-1 (Fragment)THBS1A8MZG15
TOG array regulator of axonemal microtubules protein 2 (Crescerin-2)TOGARAM2 FAM179AQ6ZUX35
Toll interacting protein variant (Fragment)0Q59FB95
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