EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
TPR protein (Fragment)TPRQ504U65
Transcobalamin-1 (TC-1) (Haptocorrin) (HC) (Protein R) (Transcobalamin I) (TC I) (TCI)TCN1 TC1P200615
Transcription factor 25 (TCF-25) (Nuclear localized protein 1)TCF25 KIAA1049 NULP1 FKSG26Q9BQ705
Transcription factor A, mitochondrial (Fragment)TFAMH7BYN35
Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)TFAP2A AP2TF TFAP2P055495
Transcription factor TFIIIB component B'' homolog (Transcription factor IIIB 150) (TFIIIB150) (Transcription factor-like nuclear regulator)BDP1 KIAA1241 KIAA1689 TFNRA6H8Y15
Transient receptor potential cation channel subfamily M member 2 (Estrogen-responsive element-associated gene 1 protein) (Long transient receptor potential channel 2) (LTrpC-2) (LTrpC2) (Transient receptor potential channel 7) (TrpC7) (Transient receptor potential melastatin 2)TRPM2 EREG1 KNP3 LTRPC2 TRPC7O947595
Translation initiation factor IF-2, mitochondrial (IF-2(Mt)) (IF-2Mt) (IF2(mt))MTIF2P461995
Transmembrane protein 100TMEM100Q9NV295
Transmembrane protein 185B (Protein FAM11B)TMEM185B FAM11BQ9H7F45
Transmembrane protein 189TMEM189 KUAA5PLL75
Transmembrane protein 198TMEM198Q66K665
Transmembrane protein 248TMEM248 C7orf42Q9NWD85
Transmembrane protein 52BTMEM52B C12orf59 UNQ5927/PRO19821Q4KMG95
TransthyretinTTR HEL111 hCG_25470E9KL365
Trefoil factor 3 (Intestinal trefoil factor) (hITF) (Polypeptide P1.B) (hP1.B)TFF3 ITF TFIQ076545
tRNA (uracil-5-)-methyltransferase homolog A (EC 2.1.1.-) (HpaII tiny fragments locus 9c protein)TRMT2A HTF9CQ8IZ695
Tropomyosin 1 alpha variant 60Q1ZYL55
Trypsin-1PRSS1E7EQ645
TUBA1C proteinTUBA1CQ8N5325
Tubulin alpha chainTUBA2 hCG_19100Q1ZYQ15
Tubulin alpha chain0B3KPS35
Tubulin alpha chain (Fragment)0Q53GA75
Tubulin alpha-1B chain (Fragment)TUBA1BF8VX095
Tubulin alpha-4A chain (Fragment)TUBA4AC9JDL25
Tubulin alpha-8 chain (Fragment)TUBA8C9K0S65
Tubulin beta chainTUBB2CQ8IZ295
Tubulin beta-4A chainTUBB4AM0R0X05
Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (HOTTL) (Tubulin--tyrosine ligase-like protein 3)TTLL3 PRO0207Q9Y4R75
Tubulin-specific chaperone ATBCAE5RIW35
Tudor and KH domain-containing protein (Tudor domain-containing protein 2)TDRKH TDRD2Q9Y2W65
Tudor domain-containing protein 3TDRD3Q9H7E25
Tumor necrosis factor ligand superfamily member 9 (4-1BB ligand) (4-1BBL)TNFSF9P412735
Tumor necrosis factor receptor superfamily member 6B (Decoy receptor 3) (DcR3) (Decoy receptor for Fas ligand) (M68)TNFRSF6B DCR3 TR6 UNQ186/PRO212O954075
Tumor necrosis factor-inducible gene 6 protein (Hyaluronate-binding protein) (TNF-stimulated gene 6 protein) (TSG-6) (Tumor necrosis factor alpha-induced protein 6) (TNF alpha-induced protein 6)TNFAIP6 TSG6P980665
Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33)TUSC3 N33Q134545
Type II inositol 1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.36) (75 kDa inositol polyphosphate-5-phosphatase) (Phosphoinositide 5-phosphatase) (5PTase)INPP5B OCRL2P320195
Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)FER TYK3P165915
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (Interleukin-2-inducible T-cell kinase) (IL-2-inducible T-cell kinase) (Kinase EMT) (T-cell-specific kinase) (Tyrosine-protein kinase Lyk)ITK EMT LYKQ088815
Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)JAK3P523335
Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1)PTPN21 PTPD1Q168255
U2 small nuclear RNA auxiliary factor 2 isoform bU2AF2B5BU255
U2 small nuclear RNA auxillary factor 1 isoform aU2AF1B5BU085
U3 small nucleolar RNA-associated protein 6 homolog (Hepatocellular carcinoma-associated antigen 66) (Multiple hat domains protein)UTP6 C17orf40 HCA66 MHATQ9NYH95
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 snRNP 27 kDa protein) (U4/U6.U5-27K) (Nucleic acid-binding protein RY-1) (U4/U6.U5 tri-snRNP-associated 27 kDa protein) (27K) (U4/U6.U5 tri-snRNP-associated protein 3)SNRNP27Q8WVK25
Ubiquinol-cytochrome-c reductase complex assembly factor 1 (Basic FGF-repressed Zic-binding protein) (bFGF-repressed Zic-binding protein) (bFZb) (Ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog)UQCC1 BZFB C20orf44 UQCCQ9NVA15
Ubiquitin C splice variantUBCQ5UGI35
Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12)USP12 UBH1 USP12L1O753175
Ubiquitin carboxyl-terminal hydrolase MINDY-2 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-2) (Protein FAM63B)MINDY2 FAM63B KIAA1164Q8NBR65
Ubiquitin thioesterase OTUB1OTUB1F5GYJ85
Ubiquitin-conjugating enzyme E2 J1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme J1) (Non-canonical ubiquitin-conjugating enzyme 1) (NCUBE-1) (Yeast ubiquitin-conjugating enzyme UBC6 homolog E) (HsUBC6e)UBE2J1 NCUBE1 CGI-76 HSPC153 HSPC205Q9Y3855
Ubiquitin-conjugating enzyme E2 R2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme R2) (Ubiquitin carrier protein R2) (Ubiquitin-conjugating enzyme E2-CDC34B) (Ubiquitin-protein ligase R2)UBE2R2 CDC34B UBC3BQ712K35
Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)ATG12 APG12 APG12LO948175
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 (BGnT-8) (Beta-1,3-Gn-T8) (Beta-1,3-N-acetylglucosaminyltransferase 8) (Beta3Gn-T8) (EC 2.4.1.-)B3GNT8 B3GALT7 BGALT15Q7Z7M85
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 (BGnT-9) (Beta-1,3-Gn-T9) (Beta-1,3-N-acetylglucosaminyltransferase 9) (Beta3Gn-T9) (EC 2.4.1.-)B3GNT9 UNQ1922/PRO4397Q6UX725
UHRF1-binding protein 1-likeUHRF1BP1L KIAA0701A0JNW55
Uncharacterized proteinDKFZp686P15220Q6N0895
Uncharacterized protein0H3BT365
Uncharacterized protein (Fragment)0H0YGG75
Uncharacterized protein (Fragment)0K7ESF45
Uncharacterized protein (Fragment)0M0QZ245
Uncharacterized protein C12orf29C12orf29Q8N9995
Uncharacterized protein C19orf43C19orf43Q9BQ615
Uncharacterized protein C19orf68C19orf68Q86XI85
Unconventional myosin-IdMYO1DK7EIG75
Unconventional myosin-Ih (Myosin-1H)MYO1HQ8N1T35
Unconventional myosin-XVI (Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3) (Unconventional myosin-16)MYO16 KIAA0865 MYO16B NYAP3Q9Y6X65
UPF0415 protein C7orf25C7orf25Q9BPX75
Uridine diphosphate glucose pyrophosphatase (UDPG pyrophosphatase) (UGPPase) (EC 3.6.1.45) (Nucleoside diphosphate-linked moiety X motif 14) (Nudix motif 14)NUDT14 UGPPO958485
Uroplakin-1bUPK1BE7ETN95
V-set domain-containing T-cell activation inhibitor 1 (B7 homolog 4) (B7-H4) (B7h.5) (Immune costimulatory protein B7-H4) (Protein B7S1) (T-cell costimulatory molecule B7x)VTCN1 B7H4 UNQ659/PRO1291Q7Z7D35
V1-17 protein (Fragment)V1-17A2MYD05
V1-22 protein (Fragment)V1-22Q5NV885
V3-3 protein (Fragment)V3-3Q5NV835
V5-6 protein (Fragment)V5-6Q5NV925
Vacuolar protein sorting-associated protein 28 homolog (Fragment)VPS28E9PM905
Vacuolar protein sorting-associated protein 29 (Vesicle protein sorting 29)VPS29F8VXU55
Vacuolar protein sorting-associated protein VTA1 homologVTA1Q5TGM05
VAMP (Vesicle-associated membrane protein)-associated protein B and C (VAMP (Vesicle-associated membrane protein)-associated protein B and C, isoform CRA_b) (cDNA FLJ13179 fis, clone NT2RP3003918, highly similar to Vesicle-associated membrane protein-associated protein B/C)VAPB hCG_26693Q53XM75
Vang-like protein 2 (Loop-tail protein 1 homolog) (Strabismus 1) (Van Gogh-like protein 2)VANGL2 KIAA1215 STB1Q9ULK55
Vascular non-inflammatory molecule 2 (Vanin-2) (EC 3.5.1.92) (Glycosylphosphatidyl inositol-anchored protein GPI-80) (Protein FOAP-4)VNN2O954985
VCP protein (Fragment)VCPQ96IF95
Versican core proteinVCANE9PF175
Vesicle transport protein SFT2A (SFT2 domain-containing protein 1) (pRGR1)SFT2D1 C6orf83Q8WV195
VIP peptides [Cleaved into: Intestinal peptide PHV-42 (Peptide histidine valine 42); Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)]VIPP012825
Vitamin D-binding proteinGCD6RBJ75
Vitamin K-dependent gamma-carboxylase (EC 4.1.1.90) (Gamma-glutamyl carboxylase) (Peptidyl-glutamate 4-carboxylase) (Vitamin K gamma glutamyl carboxylase)GGCX GCP384355
Voltage-dependent L-type calcium channel subunit alpha-1S (Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle) (Voltage-gated calcium channel subunit alpha Cav1.1)CACNA1S CACH1 CACN1 CACNL1A3Q136985
VPS10 domain-containing receptor SorCS1 (hSorCS)SORCS1 SORCSQ8WY215
VPS4B protein (Fragment)VPS4BQ6PJZ45
WAP four-disulfide core domain protein 8 (Putative protease inhibitor WAP8)WFDC8 C20orf170 WAP8Q8IUA05
WD repeat-containing protein 18 (Fragment)WDR18U3KQC15
WD repeat-containing protein 19 (Intraflagellar transport 144 homolog)WDR19 IFT144 KIAA1638Q8NEZ35
WD repeat-containing protein 59WDR59 KIAA1923 FP977Q6PJI95
Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor)WAPL FOE KIAA0261 WAPALQ7Z5K25
Zinc finger C3H1 domain-containing protein (Coiled-coil domain-containing protein 131) (Proline/serine-rich coiled-coil protein 2)ZFC3H1 CCDC131 KIAA0546 PSRC2O602935
Zinc finger CCCH domain-containing protein 4ZC3H4 C19orf7 KIAA1064Q9UPT85
Zinc finger FYVE domain-containing protein 26 (FYVE domain-containing centrosomal protein) (FYVE-CENT) (Spastizin)ZFYVE26 KIAA0321Q68DK25
Zinc finger HIT domain-containing protein 2 (Protein FON)ZNHIT2 C11orf5Q9UHR65
Zinc finger MYM-type protein 2 (Fused in myeloproliferative disorders protein) (Rearranged in atypical myeloproliferative disorder protein) (Zinc finger protein 198)ZMYM2 FIM RAMP ZNF198Q9UBW75
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