EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Angiopoietin-1 receptor (EC 2.7.10.1) (Endothelial tyrosine kinase) (Tunica interna endothelial cell kinase) (Tyrosine kinase with Ig and EGF homology domains-2) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)TEK TIE2 VMCM VMCM1Q027634
Angiotensin I converting enzyme (Peptidyl-dipeptidase A) 1, isoform CRA_iACE hCG_41821D3DU134
Angiotensinogen variant (Fragment)0Q53GY34
Ankyrin repeat and zinc finger domain-containing protein 1 (Zinc finger protein 744)ANKZF1 ZNF744Q9H8Y54
Ankyrin repeat domain-containing protein 18AANKRD18A KIAA2015Q8IVF64
Ankyrin repeat domain-containing protein 18BANKRD18BA2A2Z94
Ankyrin repeat domain-containing protein 20B (Ankyrin repeat domain-containing protein 20A pseudogene)ANKRD20A8P ANKRD20BQ5CZ794
Annexin0B2R7L24
Annexin0B4DQE14
AnnexinANXA5D6RBL54
Annexin (Fragment)ANXA6E5RJR04
Annexin (Fragment)ANXA3D6RFG54
Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II)ANXA4 ANX4B4DDF94
Annexin A6ANXA6E5RIU84
Annexin A6 (67 kDa calelectrin) (Annexin VI) (Annexin-6) (Calphobindin-II) (CPB-II) (Chromobindin-20) (Lipocortin VI) (Protein III) (p68) (p70)ANXA6 ANX6B7Z8A74
Anoctamin-8 (Transmembrane protein 16H)ANO8 KIAA1623 TMEM16HQ9HCE94
Anti-mucin1 light chain variable region (Fragment)0A2JA194
Anti-RhD monoclonal T125 gamma1 heavy chain0Q5EFE54
Anti-RhD monoclonal T125 kappa light chain0Q5EFE64
AP complex subunit beta0A8K9164
AP-2 complex subunit alpha-2AP2A2E9PR624
AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5)AP5Z1 KIAA0415 SPG48O432994
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)TP53BP2 ASPP2 BBPQ136254
Aquaporin 1AQP1B4F4P64
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (Centaurin-delta-1) (Cnt-d1) (Protein PARX)ARAP2 CENTD1 KIAA0580Q8WZ644
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1)ASAP3 DDEFL1 UPLC1Q8TDY44
Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein)RERE ARG ARP ATN1L KIAA0458Q9P2R64
Arginine/serine-rich protein PNISR (PNN-interacting serine/arginine-rich protein) (SR-related protein) (SR-rich protein) (Serine/arginine-rich-splicing regulatory protein 130) (SRrp130) (Splicing factor, arginine/serine-rich 130) (Splicing factor, arginine/serine-rich 18)PNISR C6orf111 SFRS18 SRRP130 HSPC261 HSPC306Q8TF014
Armadillo repeat gene deletes in velocardiofacial syndrome (Armadillo repeat gene deletes in velocardiofacial syndrome, isoform CRA_b)ARVCF hCG_17887B9EH954
Arp2/3 complex 34 kDa subunit0Q9BXV54
Arrestin domain-containing protein 1ARRDC1F2Z3I44
Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)ARNT BHLHE2P275404
Arylacetamide deacetylase (EC 3.1.1.3)AADAC DACP227604
AshwinC2orf49Q9BVC54
Asparagine synthetase [glutamine-hydrolyzing] (EC 6.3.5.4) (Cell cycle control protein TS11) (Glutamine-dependent asparagine synthetase)ASNS TS11B4DXZ14
Aspartate aminotransferase (EC 2.6.1.1)0B3KUZ84
Aspartyl aminopeptidaseDNPEPE7EMB64
Aspartyl aminopeptidase (Fragment)DNPEPC9JRG34
AT-rich interactive domain-containing protein 1B (ARID domain-containing protein 1B) (BRG1-associated factor 250b) (BAF250B) (BRG1-binding protein hELD/OSA1) (Osa homolog 2) (hOsa2) (p250R)ARID1B BAF250B DAN15 KIAA1235 OSA2Q8NFD54
ATP synthase F(0) complex subunit B1, mitochondrialATP5F1Q5QNZ24
ATP synthase subunit beta, mitochondrial (Fragment)ATP5BF8W0P74
ATP synthase subunit g, mitochondrialATP5LE9PN174
ATP synthase subunit gamma0B4DL144
ATP-binding cassette sub-family A member 3 (ABC-C transporter) (ATP-binding cassette transporter 3) (ATP-binding cassette 3)ABCA3 ABC3Q997584
ATP-binding cassette sub-family A member 9ABCA9Q8IUA74
ATP-binding cassette sub-family B member 10, mitochondrial (ATP-binding cassette transporter 10) (ABC transporter 10 protein) (Mitochondrial ATP-binding cassette 2) (M-ABC2)ABCB10Q9NRK64
ATP-binding cassette sub-family B member 8, mitochondrial (Mitochondrial ATP-binding cassette 1) (M-ABC1)ABCB8 MABC1Q9NUT24
ATP-dependent RNA helicase DDX1DDX1F1T0B34
ATP-dependent RNA helicase DHX8DHX8F5H6584
ATPase H+ transporting V0 subunit D1 (Fragment)ATP6V0D1C6SUN64
ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B, isoform 2 variant (Fragment)0Q59HF34
Atypical kinase COQ8B, mitochondrial (EC 2.7.-.-) (AarF domain-containing protein kinase 4) (Coenzyme Q protein 8B)COQ8B ADCK4Q96D534
Autoantigen La (Fragment)SSBB5BUB54
B-cell linker protein (B-cell adapter containing a SH2 domain protein) (B-cell adapter containing a Src homology 2 domain protein) (Cytoplasmic adapter protein) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (SLP-65)BLNK BASH SLP65Q8WV284
BAG family molecular chaperone regulator 1 (BAG-1) (Bcl-2-associated athanogene 1)BAG1 HAPQ999334
Bardet-Biedl syndrome 1 protein (BBS2-like protein 2)BBS1 BBS2L2Q8NFJ94
Bardet-Biedl syndrome 2 proteinBBS2Q9BXC94
Basigin (Fragment)BSGR4GMX54
Bax epsilon (Fragment)0O950744
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)BCL2L2 BCLW KIAA0271Q928434
Beta-1,3-galactosyltransferase 6 (Beta-1,3-GalTase 6) (Beta3Gal-T6) (Beta3GalT6) (EC 2.4.1.134) (GAG GalTII) (Galactosyltransferase II) (Galactosylxylosylprotein 3-beta-galactosyltransferase) (UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6)B3GALT6Q96L584
Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GalNAcT3) (Beta4GalNAc-T3) (Beta4GalNAcT3) (EC 2.4.1.244) (Beta-1,4-N-acetylgalactosaminyltransferase III) (N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 2) (NGalNAc-T2)B4GALNT3Q6L9W64
Beta-adrenergic receptor kinase 2 (Beta-ARK-2) (EC 2.7.11.15) (G-protein-coupled receptor kinase 3)GRK3 ADRBK2 BARK2P356264
Beta-galactosidase-1-like protein (EC 3.2.1.-)GLB1L UNQ229/PRO262Q6UWU24
Beta-hexosaminidase subunit beta (Fragment)HEXBH0YA834
Beta-synucleinSNCBQ161434
BICD family-like cargo adapter 2 (Bicaudal D-related protein 2) (BICD-related protein 2) (BICDR-2) (Coiled-coil domain-containing protein 64B)BICDL2 BICDR2 CCDC64BA1A5D94
Bile salt sulfotransferase (EC 2.8.2.14) (Dehydroepiandrosterone sulfotransferase) (DHEA-ST) (Hydroxysteroid Sulfotransferase) (HST) (ST2) (ST2A3) (Sulfotransferase 2A1) (ST2A1)SULT2A1 HST STDQ065204
Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC-1 subunit 5) (Protein Muted homolog)BLOC1S5 MUTEDQ8TDH94
Bombesin receptor subtype-3 (BRS-3)BRS3P322474
Bone morphogenetic protein 15 (BMP-15) (Growth/differentiation factor 9B) (GDF-9B)BMP15 GDF9BO959724
Bone morphogenetic protein 3 (BMP-3) (Bone morphogenetic protein 3A) (BMP-3A) (Osteogenin)BMP3 BMP3AP126454
Bone morphogenetic protein 6 (BMP-6) (VG-1-related protein) (VG-1-R) (VGR-1)BMP6 VGRP220044
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)BMPR1A ACVRLK3 ALK3P368944
Brain-specific angiogenesis inhibitor 1-associated protein 2BAIAP2I3L3C54
Brain-specific angiogenesis inhibitor 1-associated protein 2 (Fragment)BAIAP2I3L1254
Brain-specific angiogenesis inhibitor 1-associated protein 2 (Fragment)BAIAP2I3L3C64
Branched-chain-amino-acid aminotransferase, mitochondrial (BCAT(m)) (EC 2.6.1.42) (Placental protein 18) (PP18)BCAT2 BCATM BCT2 ECA40O153824
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)BARD1Q997284
BRCA2-interacting transcriptional repressor EMSYEMSY C11orf30 GL002Q7Z5894
BRO1 domain-containing protein BROX (BRO1 domain- and CAAX motif-containing protein)BROX BROFTI C1orf58B7Z9G54
Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)BRD1 BRL BRPF2O956964
BTB/POZ domain-containing protein KCTD1 (Potassium channel tetramerization domain-containing protein 1)KCTD1 C18orf5Q719H94
BTB/POZ domain-containing protein KCTD21KCTD21Q4G0X44
Butyrophilin subfamily 3 member A1 (CD antigen CD277)BTN3A1 BTF5O004814
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]MTHFD1 MTHFC MTHFDG3V2B84
C-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20) [Cleaved into: CCL20(1-67); CCL20(1-64); CCL20(2-70)]CCL20 LARC MIP3A SCYA20P785564
C-type lectin domain family 1 member B (C-type lectin-like receptor 2) (CLEC-2)CLEC1B CLEC2 UNQ721/PRO1384Q9P1264
C-type lectin domain family 5 member A (C-type lectin superfamily member 5) (Myeloid DAP12-associating lectin 1) (MDL-1)CLEC5A CLECSF5 MDL1Q9NY254
Cadherin-like and PC-esterase domain-containing protein 1CPED1 C7orf58 UNQ9432/PRO34713A4D0V74
Calcipressin-3 (Down syndrome candidate region 1-like protein 2) (Myocyte-enriched calcineurin-interacting protein 3) (MCIP3) (Regulator of calcineurin 3)RCAN3 DSCR1L2Q9UKA84
Calcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I)CALCA CALC1P068814
Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)CALCRL CGRPRQ166024
Calcium uptake protein 2, mitochondrial (EF-hand domain-containing family member A1)MICU2 EFHA1Q8IYU84
Calcium-binding mitochondrial carrier protein SCaMC-2 (Mitochondrial ATP-Mg/Pi carrier protein 3) (Mitochondrial Ca(2+)-dependent solute carrier protein 3) (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)SLC25A25 APC3 KIAA1896 MCSC3 SCAMC2 UNQ549/PRO1106Q6KCM74
Calcium-transporting ATPase (EC 3.6.3.8)ATP2B1E7ERY94
Calcyclin binding proteinCACYBPQ6NVY04
CalmeginCLGNO149674
Calpain 2, large [catalytic] subunit variant (Fragment)0Q59EF64
Calpain small subunit 1CAPNS1K7ELJ74
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