EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
SH3 domain-binding glutamic acid-rich-like protein 3Sh3bgrl3I7HPY01
SH3 domain-binding protein 1Sh3bp1A2A5V21
SH3 domain-binding protein 1Sh3bp1S4R2D31
SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK)Sh3bp5 SabQ9Z1311
SH3 domain-containing protein 19 (Kryn)Sh3d19Q91X431
SH3 domain-containing YSC84-like protein 1Sh3yl1O086411
Short coiled-coil proteinScoc ScocoQ78YZ61
Short stature homeobox protein 2 (Homeobox protein Og12X) (OG-12) (Paired family homeodomain protein Prx3)Shox2 Og12x Prx3P703901
Short/branched chain-specific acyl-CoA dehydrogenase, mitochondrialAcadsbE9Q5L31
Shugoshin 2 (Shugoshin-2) (Shugoshin-like 2)Sgo2 Sgol2 Sgol2aQ7TSY81
Sialidase-1 (EC 3.2.1.18) (G9 sialidase) (Lysosomal sialidase) (N-acetyl-alpha-neuraminidase 1)Neu1 NeuO356571
Sialidase-3 (EC 3.2.1.18) (Ganglioside sialidase) (Membrane sialidase) (N-acetyl-alpha-neuraminidase 3)Neu3Q9JMH71
Sickle tail protein (Enhancer trap locus 4)Skt Etl4 Kiaa1217A2AQ251
SID1 transmembrane family member 2 (Fragment)Sidt2E0CXC71
Sideroflexin-5Sfxn5Q925N01
Signal peptidase complex catalytic subunit SEC11 (EC 3.4.21.89)Sec11a Sec11l1 mCG_15305D3YTS11
Signal peptidase complex catalytic subunit SEC11 (EC 3.4.21.89)Sec11a Sec11l1 mCG_15305D3Z5691
Signal peptidase complex catalytic subunit SEC11C (Fragment)Sec11cD3Z5H31
Signal peptide, CUB and EGF-like domain-containing protein 1Scube1Q6NZL81
Signal peptide, CUB and EGF-like domain-containing protein 3Scube3Q66PY11
Signal recognition particle subunit SRP68 (SRP68)Srp68A2AAN21
Signal transducer and activator of transcriptionStat5aB2C3G81
Signal transducer and activator of transcriptionStat3B7ZC181
Signal transducer and activator of transcription 5A (Mammary gland factor)Stat5a Mgf MpfP422301
Signal transducer and transcription activator 6Stat6P526331
Signal transducing adapter molecule 1 (Fragment)StamA2ARJ01
Signal-induced proliferation-associated protein 1 (Sipa-1) (GTPase-activating protein Spa-1)Sipa1 Spa-1 Spa1P460621
Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog)Suds3 Sds3Q8BR651
Sister chromatid cohesion protein PDS5 homolog BPds5bF8WHU51
Slc12a6 proteinSlc12a6 Gm21985Q6P6P51
SLIT and NTRK-like protein 2Slitrk2Q810C01
Slit homolog 2 proteinSlit2G3UY211
Slit homolog 2 proteinSlit2G3UYX71
Slit homolog 2 proteinSlit2G3X9091
SLIT-ROBO Rho GTPase-activating protein 1Srgap1D3YZW11
Small kinetochore-associated proteinKnstrn D2Ertd750eA3KGG81
Small kinetochore-associated protein (Fragment)Knstrn D2Ertd750eF7BE711
Small kinetochore-associated protein (Fragment)Knstrn D2Ertd750eH3BKK21
Small kinetochore-associated protein (SKAP) (Kinetochore-localized astrin-binding protein) (Kinastrin) (Kinetochore-localized astrin/SPAG5-binding protein) (TRAF4-associated factor 1)Knstrn D2Ertd750e Skap Traf4af1Q9D9Z11
Small nuclear ribonucleoprotein ESnrpeE9Q4F41
Small nuclear ribonucleoprotein E (Fragment)SnrpeE9PZG91
Small subunit processome component 20 homologUtp20E9QK831
Small ubiquitin-related modifier 3 (SUMO-3) (SMT3 homolog 1) (Ubiquitin-like protein SMT3A) (Smt3A)Sumo3 Smt3a Smt3h1Q9Z1721
SmoothelinSmtnD3Z3Q31
Sn1-specific diacylglycerol lipase beta (DGL-beta) (EC 3.1.1.-)DaglbQ91WC91
SNW domain-containing protein 1Snw1A0A0B4J1E21
Sodium bicarbonate transporter-like protein 11 (Bicarbonate transporter-related protein 1) (Sodium borate cotransporter 1) (NaBC1) (Solute carrier family 4 member 11)Slc4a11 BTR1A2AJN71
Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6)Scn8a Nbna1Q9WTU31
Sodium- and chloride-dependent glycine transporter 1Slc6a9E9Q3V01
Sodium- and chloride-dependent glycine transporter 1Slc6a9E9Q5171
Sodium- and chloride-dependent glycine transporter 2 (GlyT-2) (GlyT2) (Solute carrier family 6 member 5)Slc6a5 Glyt2Q761V01
Sodium-coupled monocarboxylate transporter 1 (Electrogenic sodium monocarboxylate cotransporter) (Solute carrier family 5 member 8)Slc5a8 Smct Smct1Q8BYF61
Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3)Slc38a4 Ata3 Nat3 Snat4Q8R1S91
Sodium-dependent multivitamin transporter (Na(+)-dependent multivitamin transporter) (Solute carrier family 5 member 6)Slc5a6Q5U4D81
Sodium-dependent neutral amino acid transporter B(0)AT2 (Sodium- and chloride-dependent neurotransmitter transporter NTT73) (Solute carrier family 6 member 15) (Transporter v7-3)Slc6a15 B0at2 Ntt73Q8BG161
Sodium-dependent neutral amino acid transporter SLC6A17 (Sodium-dependent neurotransmitter transporter NTT4) (Solute carrier family 6 member 17)Slc6a17 Ntt4Q8BJI11
Sodium-dependent noradrenaline transporter (Norepinephrine transporter) (NET) (Solute carrier family 6 member 2)Slc6a2O551921
Sodium/hydrogen exchangerSlc9a6A1L3P41
Sodium/hydrogen exchangerSlc9a8A2A4641
Sodium/hydrogen exchangerSlc9a6B0QZV31
Sodium/hydrogen exchangerSlc9a2Q3ZAS01
Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8)Slc9a8 Nhe8Q8R4D11
Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9)Slc9a9 Nhe9Q8BZ001
Sodium/hydrogen exchanger 9B2 (NHA-oc) (Na(+)/H(+) exchanger NHA2) (Na(+)/H(+) exchanger-like domain-containing protein 2) (NHE domain-containing protein 2) (Soditlum/hydrogen exchanger-like domain-containing protein 2) (Solute carrier family 9 subfamily B member 2)Slc9b2 Nha2 Nhedc2Q5BKR21
Sodium/potassium-transporting ATPase subunit alpha (EC 3.6.3.-)Atp1a3 mCG_7257A0A0G2JGX41
Sodium/potassium-transporting ATPase subunit alpha (EC 3.6.3.-) (Fragment)Atp1a3Q8R0B01
Sodium/potassium-transporting ATPase subunit betaAtp1b1 mCG_9368Q545P01
Sodium/potassium-transporting ATPase subunit betaAtp1b2 mCG_20899 RP23-56I20.2-001Q3UR551
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 (Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 4) (Protein FAM77A)Nkain4 Fam77aQ9JMG41
Solute carrier family 12 member 4Slc12a4F8WIJ01
Solute carrier family 2, facilitated glucose transporter member 4Slc2a4J3QK171
Solute carrier family 22 member 5 (High-affinity sodium-dependent carnitine cotransporter) (Organic cation/carnitine transporter 2)Slc22a5 Octn2Q9Z0E81
Solute carrier family 26 member 6Slc26a6A0A0A0MQB31
Solute carrier family 26 member 6 (Anion exchange transporter) (Chloride-formate exchanger) (Pendrin-L1) (Pendrin-like protein 1) (Putative anion transporter-1) (Pat-1)Slc26a6 Cfex Pat1Q8CIW61
Solute carrier family 27 (fatty acid transporter), member 6Slc27a6E9Q9W41
Solute carrier family 35 member G1 (Transmembrane protein 20)Slc35g1 Tmem20Q8BY791
Solute carrier family 45 member 4 (Fragment)Slc45a4F7BEQ11
Solute carrier organic anion transporter family member 1B2 (Liver-specific organic anion transporter 1) (LST-1) (SLC21A6) (Solute carrier family 21 member 10)Slco1b2 Oatp1b2 Slc21a10Q9JJL31
Solute carrier organic anion transporter family member 4C1 (Oatp-R) (Solute carrier family 21 member 20)Slco4c1 Oatp4c1 Slc21a20Q8BGD41
Somatotropin (Growth hormone)Gh1 GhP068801
Sorbin and SH3 domain-containing protein 1Sorbs1D3Z5J31
Sorbin and SH3 domain-containing protein 1Sorbs1E9PYX61
Sorbin and SH3 domain-containing protein 1Sorbs1E9QNA71
Sorbin and SH3 domain-containing protein 2 (Arg-binding protein 2) (ArgBP2) (Arg/Abl-interacting protein 2)Sorbs2 Argbp2 Kiaa0777Q3UTJ21
Sorting nexin-14Snx14G3UWA31
Sorting nexin-14Snx14G3UX331
Sorting nexin-14Snx14G3UXB61
Sorting nexin-16Snx16Q8C0801
Sorting nexin-3Snx3D3Z7891
Sorting nexin-30Snx30Q8CE501
Sorting nexin-7Snx7Q9CY181
SOSS complex subunit B1 (Nucleic acid-binding protein 2) (Oligonucleotide/oligosaccharide-binding fold-containing protein 2B) (Sensor of single-strand DNA complex subunit B1) (Sensor of ssDNA subunit B1) (SOSS-B1) (Single-stranded DNA-binding protein 1)Nabp2 Obfc2b Ssb1Q8R2Y91
SOSS complex subunit C (INTS3- and NABP-interacting protein) (Sensor of single-strand DNA complex subunit C) (Sensor of ssDNA subunit C) (SOSS-C) (Single-stranded DNA-binding protein-interacting protein 1) (SSB-interacting protein 1)Inip Ssbip1Q3TXT31
SPARC-related modular calcium-binding protein 1 (SPARC-related gene protein) (Secreted modular calcium-binding protein 1) (SMOC-1)Smoc1 SrgQ8BLY11
Spatacsin (Spastic paraplegia 11 protein homolog)Spg11 Kiaa1840Q3UHA31
Speckle targeted PIP5K1A-regulated poly(A) polymerase (Star-PAP) (EC 2.7.7.19) (RNA-binding motif protein 21) (RNA-binding protein 21) (U6 snRNA-specific terminal uridylyltransferase 1) (U6-TUTase) (EC 2.7.7.52)Tut1 Rbm21Q8R3F91
Spectrin alpha chain, non-erythrocytic 1Sptan1 Spna2E9Q4471
Spectrin beta chainSptb Spnb1 mCG_123942Q3UGX21
Spectrin beta chainSptbn2 Spnb3Q3UGZ41
Spectrin beta chain, erythrocytic (Beta-I spectrin)Sptb Spnb-1 Spnb1 Sptb1P155081
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