EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Sperm motility kinase Y (EC 2.7.11.1)Gm7168A0AUV41
Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (TPR-containing protein involved in spermatogenesis) (TPIS)Spag1 TpisQ80ZX81
Sperm-associated antigen 5 (Mastrin) (Mitotic spindle-associated protein p126) (MAP126)Spag5Q7TME21
Spermatid-specific heat shock protein 70 (Fragment)Hsc70tQ9R2A11
Spermatogenesis-associated protein 19, mitochondrial (Spermatogenic cell-specific gene 1 protein) (Spergen-1)Spata19 Spergen1Q9DAQ91
Spermatogenesis-associated protein 2-like protein (SPATA2-like protein)Spata2l Kiaa4138Q8BNN11
Spermatogenesis-associated protein 20 (Sperm-specific protein 411) (Ssp411) (Transcript increased in spermiogenesis 78 protein)Spata20 Tisp78Q80YT51
Sphingomyelin phosphodiesterase 2 (EC 3.1.4.12) (Lyso-platelet-activating factor-phospholipase C) (Lyso-PAF-PLC) (Neutral sphingomyelinase) (N-SMase) (nSMase)Smpd2O705721
Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (nSMase-2) (nSMase2) (Neutral sphingomyelinase II)Smpd3Q9JJY31
Sphingomyelin phosphodiesterase 4Smpd4E9Q1V51
Sphingomyelin phosphodiesterase 4Smpd4E9Q9141
Sphingomyelin phosphodiesterase 4Smpd4E9Q9L11
Sphingomyelin phosphodiesterase 4Smpd4E9Q0L71
Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III)Smpd4 Kiaa1418Q6ZPR51
Sphingosine kinase 1 (SK 1) (SPK 1) (EC 2.7.1.91)Sphk1Q8CI151
Sphingosine kinase 2 (SK 2) (SPK 2) (EC 2.7.1.91)Sphk2Q9JIA71
Spindle assembly abnormal protein 6 homologSass6 Sas6Q80UK71
Splicing factor 3A subunit 2 (Splicing factor 3a, subunit 2, isoform CRA_c)Sf3a2 mCG_12094D3YW091
Splicing factor 45 (Fragment)Rbm17A2AP401
Splicing factor ESS-2 homolog (ES2 protein) (Expressed sequence 2 embryonic lethal)Ess2 Dgcr14 Dgsi Es2 Es2elO702791
Splicing factor, suppressor of white-apricot homolog (Splicing factor, arginine/serine-rich 8) (Suppressor of white apricot protein homolog)Sfswap Sfrs8 Srsf8 SwapQ3USH51
Spondin-1 (F-spondin)Spon1Q8VCC91
Spondin-2 (Mindin)Spon2Q8BMS21
Squalene monooxygenase (EC 1.14.14.17) (Squalene epoxidase) (SE)Sqle Erg1P520191
SR-related CTD-associated factor 11Scaf11E9PZM71
SRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap)Srcin1 Kiaa1684 P140Q9QWI61
Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1)Stab1 Feel1Q8R4Y41
Stanniocalcin-2 (STC-2)Stc2O884521
StAR-related lipid transfer protein 4 (START domain-containing protein 4) (StARD4)Stard4Q99JV51
StAR-related lipid transfer protein 9 (Kinesin-like protein Kif16a) (START domain-containing protein 9) (StARD9)Stard9 Kiaa1300 Kif16aQ80TF61
START domain-containing protein 10Stard10E9PVP01
StathminStmn1D3Z5N21
Stathmin domain-containing protein 1Stmnd1 Gm1574Q6P3A11
Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10)Stmn2 Scg10 Scgn10 Stmb2P558211
Sterile alpha motif domain-containing protein 9-like (SAM domain-containing protein 9-like)Samd9l Kiaa2005Q69Z371
Steroid hormone receptor ERR1 (Estrogen receptor-like 1) (Estrogen-related receptor alpha) (ERR-alpha) (Nuclear receptor subfamily 3 group B member 1)Esrra Err1 Estrra Nr3b1O085801
Steroid receptor RNA activator 1 (Fragment)Sra1G3X8R21
Steroid receptor RNA activator 1 (Steroid receptor RNA activator protein) (SRAP)Sra1Q80VJ21
Steryl-sulfatase (EC 3.1.6.2) (Arylsulfatase C) (ASC) (Steroid sulfatase) (Steryl-sulfate sulfohydrolase)StsP504271
Striated muscle-specific serine/threonine-protein kinaseSpegE9QQ251
Stromal cell-derived factor 2 (SDF-2)Sdf2Q9DCT51
Stromal interaction molecule 2Stim2 Kiaa1482P830931
Stromal interaction molecule 2Stim2I1E4X81
Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2)Mmp10O551231
Stromelysin-3 (SL-3) (ST3) (EC 3.4.24.-) (Matrix metalloproteinase-11) (MMP-11)Mmp11Q028531
Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B)Smc1b Smc1l2Q920F61
Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (mSMC6)Smc6 Kiaa4103 Smc6l1Q924W51
Sulfatase-modifying factor 1Sumf1E9Q0Z71
Sulfatase-modifying factor 1Sumf1E9Q2651
Sulfatase-modifying factor 2 (C-alpha-formylglycine-generating enzyme 2)Sumf2Q8BPG61
Sulfate transporter (Diastrophic dysplasia protein homolog) (ST-OB) (Solute carrier family 26 member 2)Slc26a2 Dtd DtdstQ622731
Sulfate transporter (Fragment)Slc26a2E9PZ061
Sulfotransferase (EC 2.8.2.-)Sult1a1D3Z3G51
Sulfotransferase (EC 2.8.2.-) (Fragment)Hs3st1D3YUR41
Sulfotransferase 1 family member D1 (ST1D1) (EC 2.8.2.-) (Amine N-sulfotransferase) (SULT-N) (Dopamine sulfotransferase Sult1d1) (Tyrosine-ester sulfotransferase)Sult1d1 St1d1Q3UZZ61
SUMO-conjugating enzyme (EC 2.3.2.-) (Fragment)Ube2iG3UYP01
SUN domain-containing ossification factor (Membrane protein CH1) (Protein osteopotentia) (SUN-like protein 1)Suco OptQ8C3411
Suppressor of cytokine signaling 7 (SOCS-7)Socs7 Cish7 Nap4Q8VHQ21
Suppressor of IKBKE 1 (Suppressor of IKK-epsilon)Sike1Q9CPR71
Surfeit locus protein 1Surf1 Surf-1P099251
Surfeit locus protein 4Surf4E0CXD91
SURP and G-patch domain-containing protein 1 (Splicing factor 4)Sugp1 Sf4Q8CH021
Sushi-repeat-containing protein SRPX (DRS protein)SrpxQ9R0M31
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (mharp) (Sucrose nonfermenting protein 2-like 1)Smarcal1 HarpQ8BJL01
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (Fragment)Smarcb1F6U4151
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (Structural DNA-binding protein BRAF35)Hmg20b Braf35 Hmgx2 Smarce1rQ9Z1041
SymplekinSympkF8WJD41
Synapsin-1 (Synapsin I)Syn1 Syn-1O889351
Synapsin-2 (Synapsin II)Syn2Q643321
Synapsin-3 (Synapsin III)Syn3Q8JZP21
Synaptic functional regulator FMR1Fmr1D3Z6U81
Synaptic functional regulator FMR1Fmr1E9QAS81
Synaptic functional regulator FMR1Fmr1E9QAT01
Synaptic functional regulator FMR1Fmr1E9QNF51
Synaptogyrin-3Syngr3Q8R1911
Synaptojanin-1Synj1E9Q7S01
Synaptojanin-1 (Fragment)Synj1D3Z1M71
Synaptojanin-1 (Fragment)Synj1F7BQW71
Synaptojanin-2Synj2F8WHD81
Synaptojanin-2 (Fragment)Synj2D3Z6E71
Synaptojanin-2-binding protein (Activin receptor-interacting protein 2) (Activin receptor-interacting protein 4) (Mitochondrial outer membrane protein 25)Synj2bp Arip2 Omp25Q9D6K51
Synaptonemal complex protein 1 (SCP-1)Sycp1 Scp1Q622091
Synaptonemal complex protein 2 (SCP-2) (Synaptonemal complex lateral element protein)Sycp2 Scp2Q9CUU31
Synaptonemal complex protein 3 (SCP-3)Sycp3 Scp3P702811
SynaptopodinSynpoE9Q3E21
Synaptosomal-associated protein 47Snap47B2FDF61
Synaptotagmin-11 (Fragment)Syt11S4R1M81
Synaptotagmin-7 (Synaptotagmin VII) (SytVII)Syt7Q9R0N71
Syndecan-3 (SYND3)Sdc3 Kiaa0468Q645191
Syntaxin 4A (placental)Stx4aD6RJ291
Syntaxin 5AStx5aH3BKJ71
Syntaxin-16Stx16F6X4N51
Syntaxin-16 (Fragment)Stx16B7ZCB81
Syntaxin-1BStx1b Stx1b1 Stx1b2P612641
Syntaxin-2 (Fragment)Stx2D3YY941
Syntaxin-3Stx3 Stx3aQ8R1B71
Syntaxin-3Stx3A0A1C7CYU41
SynteninSdcbpO886011
T-cell receptor beta-2 chain C region0P018511
T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g)Cd3gP119421
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