EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48)Ptpn3A2ALK81
Tyrosine-protein phosphatase non-receptor type substrate 1SirpaE0CYM81
U1 small nuclear ribonucleoprotein A (Fragment)SnrpaD3Z0S61
U2 small nuclear ribonucleoprotein B'' (Fragment)Snrpb2A2CES41
U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10)Mphosph10Q810V01
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (U4/U6.U5 snRNP 27 kDa protein) (U4/U6.U5-27K) (U4/U6.U5 tri-snRNP-associated protein 3)Snrnp27Q8K1941
U6 snRNA-associated Sm-like protein LSm3Lsm3P623111
U6 snRNA-associated Sm-like protein LSm5Lsm5P623221
U6 snRNA-associated Sm-like protein LSm6Lsm6P623131
U6 snRNA-associated Sm-like protein LSm7Lsm7Q9CQQ81
U7 snRNA-associated Sm-like protein LSm11Lsm11Q8BUV61
U8 snoRNA-decapping enzyme (EC 3.6.1.62) (IDP phosphatase) (IDPase) (EC 3.6.1.64) (Inosine diphosphate phosphatase) (Nucleoside diphosphate-linked moiety X motif 16) (Nudix motif 16) (m7GpppN-mRNA hydrolase)Nudt16Q6P3D01
UAP56-interacting factor (Forty-two-three domain-containing protein 1) (Protein 40-2-3)Fyttd1 UifQ91Z491
Ubiquinol-cytochrome-c reductase complex assembly factor 2Uqcc2 2900010M23Rik Mnf1D3Z4C91
Ubiquinol-cytochrome-c reductase complex assembly factor 2Uqcc2 2900010M23Rik Mnf1D3Z4D61
Ubiquinol-cytochrome-c reductase complex assembly factor 2 (Mitochondrial nucleoid factor 1) (Mitochondrial protein M19)Uqcc2 Mnf1Q9CQY61
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Coenzyme Q biosynthesis protein 4 homolog)Coq4Q8BGB81
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial (Fragment)Coq4B7ZCV41
Ubiquinone biosynthesis protein COQ9, mitochondrialCoq9Q8K1Z01
Ubiquitin carboxyl-terminal hydrolase 17-like protein B (USP17-B) (EC 3.4.19.12) (Deubiquitinating enzyme 1A)Usp17lb Dub1aE9Q9U01
Ubiquitin carboxyl-terminal hydrolase 19Usp19E9Q9M51
Ubiquitin carboxyl-terminal hydrolase 19 (Ubiquitin specific peptidase 19, isoform CRA_a)Usp19 mCG_16487J3KMM11
Ubiquitin carboxyl-terminal hydrolase 24Usp24E9PV451
Ubiquitin carboxyl-terminal hydrolase 26 (EC 3.4.19.12) (Deubiquitinating enzyme 26) (Ubiquitin thioesterase 26) (Ubiquitin-specific-processing protease 26)Usp26Q99MX11
Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)Usp28 Kiaa1515Q5I0431
Ubiquitin carboxyl-terminal hydrolase 33 (EC 3.4.19.12) (Deubiquitinating enzyme 33) (Ubiquitin thioesterase 33) (Ubiquitin-specific-processing protease 33) (VHL-interacting deubiquitinating enzyme 1)Usp33 Vdu1Q8R5K21
Ubiquitin carboxyl-terminal hydrolase 34 (Fragment)Usp34F6WJB71
Ubiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40)Usp40Q8BWR41
Ubiquitin carboxyl-terminal hydrolase 46 (Fragment)Usp46D3YVJ51
Ubiquitin carboxyl-terminal hydrolase 48Usp48A2ALR91
Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific-processing protease 48)Usp48 Kiaa4202Q3V0C51
Ubiquitin carboxyl-terminal hydrolase 7Usp7F8VPX11
Ubiquitin carboxyl-terminal hydrolase 8Usp8A2AI521
Ubiquitin carboxyl-terminal hydrolase CYLDCyldZ4YJJ51
Ubiquitin conjugation factor E4 BUbe4bG3UZD61
Ubiquitin domain-containing protein UBFD1Ubfd1 D7Wsu128eQ78JW91
Ubiquitin thioesterase OTUB2 (Fragment)Otub2F6SXD21
Ubiquitin-activating enzyme E1, Chr X (Ubiquitin-like modifier activating enzyme 1)Uba1 Ube1x mCG_126518B9EHN01
Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1)Ubac2 Phgdhl1Q8R1K11
Ubiquitin-associated protein 2Ubap2A2AMY51
Ubiquitin-associated protein 2 (Fragment)Ubap2F6PYV51
Ubiquitin-associated protein 2 (UBAP-2) (Protein lingerer homolog 1) (mLig-1)Ubap2 Lig1Q91VX21
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)Ube2d1P610801
Ubiquitin-conjugating enzyme E2 E1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme E1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme E1) (UbcM3) (Ubiquitin carrier protein E1) (Ubiquitin-protein ligase E1)Ube2e1 Ubce5 Ubcm3P524821
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)Ube2e2Q91W821
Ubiquitin-conjugating enzyme E2 E2 (Fragment)Ube2e2D3YXD11
Ubiquitin-conjugating enzyme E2 E2 (Fragment)Ube2e2H3BL231
Ubiquitin-conjugating enzyme E2 E2 (Fragment)Ube2e2H3BL691
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcM2) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)Ube2e3 Ubce4 Ubcm2P524831
Ubiquitin-conjugating enzyme E2 KUbe2kD3Z4U31
Ubiquitin-conjugating enzyme E2 L3Ube2l3D3YZS31
Ubiquitin-conjugating enzyme E2 Q2Ube2q2D3Z6471
Ubiquitin-conjugating enzyme E2 Q2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q2) (Ubiquitin carrier protein Q2) (Ubiquitin-protein ligase Q2)Ube2q2Q8K2Z81
Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)Cdc34 Ubch3 Ube2r1Q8CFI21
Ubiquitin-conjugating enzyme E2 variant 1Ube2v1B7ZBY71
Ubiquitin-conjugating enzyme E2 variant 1 (Fragment)Ube2v1B7ZBY61
Ubiquitin-conjugating enzyme E2 variant 2 (Ubiquitin-conjugating enzyme E2 variant 2, isoform CRA_b)Ube2v2 mCG_126823A6X9251
Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1)Ufc1Q9CR091
Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1)Ublcp1Q8BGR91
Ubiquitin-like protein 5Ubl5E0CZB31
Ubiquitin-like protein FUBI (Monoclonal non-specific suppressor factor beta) (MNSF-beta)FauP355451
Ubiquitin-protein ligase E3A (EC 2.3.2.26) (HECT-type ubiquitin transferase E3A) (Oncogenic protein-associated protein E6-AP)Ube3aE9QKT11
Ubiquitin-protein ligase E3B (EC 2.3.2.26) (HECT-type ubiquitin transferase E3B)Ube3bQ9ES341
Ubiquitin-related modifier 1Urm1Q9D2P41
Ubiquitin-specific peptidase 31Usp31E9Q6Y81
UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-N-acetylglucosamine 4-epimerase) (UDP-GlcNAc 4-epimerase) (EC 5.1.3.7) (UDP-galactosamine 4-epimerase) (UDP-GalNAc 4-epimerase) (UDP-galactose 4-epimerase)GaleQ8R0591
UDP-glucuronosyltransferase 1-7C (UDPGT 1-7C) (UGT1*7C) (UGT1-07C) (UGT1.7C) (EC 2.4.1.17) (UDP-glucuronosyltransferase 1A7C) (UGT1A10)Ugt1a7c Ugt1a10Q6ZQM81
Ufm1-specific protease 2 (UfSP2) (EC 3.4.22.-)Ufsp2Q99K231
UMAP1-MVP12-associated (UMA) domain-containing 1 (Fragment)Umad1 Gm16039E0CZ611
Uncharacterized family 31 glucosidase KIAA1161 (EC 3.2.1.-)Kiaa1161Q69ZQ11
Uncharacterized proteinGm27029A2A4P31
Uncharacterized proteinGm27029A2A4P41
Uncharacterized proteinGm15128A2ADW81
Uncharacterized proteinGm10439A2AJU21
Uncharacterized proteinGm13697 Gm13691 Gm13693 Gm13694 Gm13696 Gm13698A2AK421
Uncharacterized proteinGm13695A2AK441
Uncharacterized proteinGm15080A2BI021
Uncharacterized proteinGm15093A2BI721
Uncharacterized proteinGm15127B1AVZ51
Uncharacterized proteinGm15091B1AZM21
Uncharacterized proteinGm15107B1B0X01
Uncharacterized proteinGm15114B1B0X61
Uncharacterized proteinGm20521 Pabpn1D3Z5F71
Uncharacterized proteinGm20498E9PVN61
Uncharacterized proteinGm20431E9PY391
Uncharacterized proteinGm15127 Gm15128E9Q1L31
Uncharacterized proteinGm15800E9Q2E41
Uncharacterized proteinGm20518 Dgcr2E9Q5481
Uncharacterized proteinGm15097E9QA141
Uncharacterized proteinGm21992F7BGR71
Uncharacterized proteinGm6768J3QND81
Uncharacterized proteinGm15097L7MU671
Uncharacterized proteinGm15294V9GXA71
Uncharacterized proteinGm28036V9GXJ11
Uncharacterized proteinGm13695J3QM481
Uncharacterized proteinGm13698 Gm13693 Gm13694 Gm13696 Gm13697J3QNR01
Uncharacterized proteinGm5039J3QNT61
Uncharacterized proteinGm37240E9QAY51
Uncharacterized proteinGm17428F6XET41
Uncharacterized proteinGm8444F6XS561
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