EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen)Strn3 Gs2na Sg2naQ9ERG28
Superkiller viralicidic activity 2-like 2 (EC 3.6.4.13) (ATP-dependent helicase SKIV2L2) (TRAMP-like complex helicase)Skiv2l2Q9CZU38
Syntaxin-6Stx6Q9JKK18
T-cell immunomodulatory protein (Protein TIP) (Integrin-alpha FG-GAP repeat-containing protein 1) (Linkin)Itfg1 D8Wsu49e Lnkn-1 TipQ99KW98
T-complex protein 1 subunit zeta-2 (TCP-1-zeta-2) (CCT-zeta-2) (Cctz-2)Cct6bQ613908
Tax1-binding protein 3 (Tax interaction protein 1) (TIP-1)Tax1bp3Q9DBG98
Tectonin beta-propeller repeat-containing protein 1Tecpr1 Kiaa1358Q80VP08
Tetraspanin-8 (Tspan-8)Tspan8Q8R3G98
Tetratricopeptide repeat protein 7B (TPR repeat protein 7B)Ttc7bE9Q6P58
Thioredoxin domain-containing protein 17 (14 kDa thioredoxin-related protein) (TRP14) (Protein 42-9-9) (Thioredoxin-like protein 5)Txndc17 Txnl5Q9CQM58
THO complex subunit 4 (Tho4) (Ally of AML-1 and LEF-1) (Aly/REF export factor) (REF1-I) (RNA and export factor-binding protein 1) (Transcriptional coactivator Aly/REF)Alyref Aly Ref1 Refbp1 THOC4O085838
THUMP domain-containing protein 3 (GtROSA26asSor)Thumpd3P977708
Thy-1 membrane glycoprotein (Thy-1 antigen) (CD antigen CD90)Thy1 Thy-1P018318
Thymidylate synthase (TS) (TSase) (EC 2.1.1.45)TymsP076078
Toll-like receptor 2 (CD antigen CD282)Tlr2Q9QUN78
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)Smarca4 Baf190a Brg1 Snf2b Snf2l4Q3TKT48
Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon)Eif2b5Q8CHW48
Transmembrane emp24 domain-containing protein 2 (COPI-coated vesicle membrane protein p24) (Membrane protein p24A) (Sid 394) (p24 family protein beta-1) (p24beta1)Tmed2 Rnp24 Sid394Q9R0Q38
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)Tpm1 Tpm-1 TpmaP587718
Tubulin alpha-8 chain (Alpha-tubulin 8)Tuba8Q9JJZ28
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain)TraddQ3U0V28
Tyrosine-protein kinase (EC 2.7.10.2)Jak1 mCG_21706B1ASP28
U3 small nucleolar RNA-associated protein 15 homolog (Src-associated protein SAW)Utp15Q8C7V38
Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46)Usp46P620698
Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47)Usp47Q8BY878
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1) (EC 3.4.19.12) (EC 6.-.-.-) (Neuron cytoplasmic protein 9.5) (PGP 9.5) (PGP9.5) (Ubiquitin thioesterase L1)Uchl1Q9R0P98
Ubiquitin carboxyl-terminal hydrolase MINDY-1 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-1) (NF-E2 inducible protein) (Protein FAM63A)Mindy1 Fam63a NiQ76LS98
Ubiquitin carboxyl-terminal hydrolase MINDY-3 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-3) (Protein CARP)MINDY3 Carp Fam188aQ9CV288
Ubiquitin domain-containing protein 2Ubtd2Q6PGH08
Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)Ubash3b Sts1Q8BGG78
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2)Ube2d2 Ubc4 Ubch4 Ubch5b Ube2d2aP628388
Uncharacterized protein C1orf198 homolog0Q8C3W18
UPF0160 protein MYG1, mitochondrial (Protein Gamm1)Myg1Q9JK818
USP6 N-terminal-like proteinUsp6nl Kiaa0019Q80XC38
UtrophinUtrnE9Q6R78
Vacuolar protein sorting-associated protein 18 homologVps18Q8R3078
Vam6/Vps39-like proteinVps39 Pldn Vam6Q8R5L38
Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1)Vangl1 Lpp2Q80Z968
Versican core protein (Chondroitin sulfate proteoglycan core protein 2) (Chondroitin sulfate proteoglycan 2) (Large fibroblast proteoglycan) (PG-M)Vcan Cspg2Q620598
Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)Vti1b Vti1l1O883848
WD repeat-containing protein 6 (mWDR6)Wdr6Q99ME28
Xaa-Pro dipeptidase (X-Pro dipeptidase) (EC 3.4.13.9) (Imidodipeptidase) (Peptidase 4) (Peptidase D) (Proline dipeptidase) (Prolidase)Pepd Pep4Q111368
1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme)Gbe1Q9D6Y97
1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E1) (Aldo-keto reductase family 1 member E2)Akr1e2 Akr1cl2 Akr1e1Q9DCT17
17beta-hydroxysteroid dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA dehydrogenase (3-hydroxyacyl-CoA dehydrogenase type-2) (Hydroxysteroid (17-beta) dehydrogenase 10) (Putative uncharacterized protein)Hsd17b10 Hadh2 Hsd17b10/SchadQ99N157
182 kDa tankyrase-1-binding proteinTnks1bp1 Kiaa1741 Tab182P588717
3-mercaptopyruvate sulfurtransferase (MST) (EC 2.8.1.2)MpstQ99J997
40S ribosomal protein S30FauP628627
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) [Cleaved into: PEX]Mmp2P334347
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAM-TS 1) (ADAM-TS1) (ADAMTS-1) (EC 3.4.24.-)Adamts1P978577
Adhesion G-protein coupled receptor G1 (G-protein coupled receptor 56) (Serpentine receptor cyt28) [Cleaved into: ADGRG1 N-terminal fragment (ADGRG1 NT) (GPR56 N-terminal fragment) (GPR56 NT) (GPR56(N)) (GPR56 extracellular subunit) (GPR56 subunit alpha); ADGRG1 C-terminal fragment (ADGRG1-CT) (GPR56 C-terminal fragment) (GPR56 CT) (GPR56(C)) (GPR56 seven-transmembrane subunit) (GPR56 7TM) (GPR56 subunit beta)]Adgrg1 Cyt28 Gpr56Q8K2097
Adipocyte plasma membrane-associated protein (Protein DD16)ApmapQ9D7N97
ADP-ribosylation factor-like protein 2Arl2Q9D0J47
ADP-ribosylation factor-like protein 6Arl6 Bbs3O888487
Afamin (Alpha-albumin) (Alpha-Alb)AfmO890207
Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase)GalmQ8K1577
Alpha-1-acid glycoprotein 1 (AGP 1) (Orosomucoid-1) (OMD 1)Orm1 Agp1 Orm-1Q605907
Alpha-1-antitrypsin 1-1 (AAT) (Alpha-1 protease inhibitor 1) (Alpha-1-antiproteinase) (Serine protease inhibitor 1-1) (Serine protease inhibitor A1a) (Serpin A1a)Serpina1a Dom1 Spi1-1P077587
Alpha-1-antitrypsin 1-5 (Alpha-1 protease inhibitor 5) (Serine protease inhibitor 1-5) (Serine protease inhibitor A1e) (Serpin A1e)Serpina1e Dom5 Spi1-5Q008987
Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Heparin-binding protein 44) (HBP-44) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP)Lrpap1P553027
Alpha-taxilinTxlna TxlnQ6PAM17
Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein)Anapc1 Mcpr Tsg24P539957
Anaphase-promoting complex subunit 2 (APC2) (Cyclosome subunit 2)Anapc2Q8BZQ77
Ankyrin repeat domain-containing protein 13AAnkrd13a Ankrd13Q80UP57
Annexin A8 (Annexin VIII) (Annexin-8)Anxa8 Anx8O356407
AP-1 complex subunit sigma-1A (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin)Ap1s1 Ap19P619677
AP2-associated protein kinase 1 (EC 2.7.11.1) (Adaptor-associated kinase 1)Aak1 Kiaa1048Q3UHJ07
Apoptosis-inducing factor 1, mitochondrial (EC 1.1.1.-) (Programmed cell death protein 8)Aifm1 Aif Pdcd8Q9Z0X17
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 (Development and differentiation-enhancing factor 2) (Paxillin-associated protein with ARF GAP activity 3) (PAG3) (Pyk2 C-terminus-associated protein) (PAP)Asap2 Ddef2 Gm1523 Gm592Q7SIG67
Ataxin-2-like proteinAtxn2l A2lpQ7TQH07
ATP synthase protein 8 (A6L) (F-ATPase subunit 8)Mtatp8 Atp8 mt-Atp8P039307
ATP-binding cassette sub-family D member 3 (68 kDa peroxisomal membrane protein) (PMP68) (70 kDa peroxisomal membrane protein) (PMP70)Abcd3 Pmp70 Pxmp1P550967
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18)Ddx18Q8K3637
ATP-dependent RNA helicase DHX29 (EC 3.6.4.13) (DEAH box protein 29)Dhx29Q6PGC17
ATP-dependent RNA helicase DHX36 (EC 3.6.4.13) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE)Dhx36 Ddx36 Kiaa1488 Mlel1Q8VHK97
Attractin (Protein mahogany)Atrn Mg MgcaQ9WU607
Beta-1,4-galactosyltransferase 1 (Beta-1,4-GalTase 1) (Beta4Gal-T1) (b4Gal-T1) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1) [Cleaved into: Processed beta-1,4-galactosyltransferase 1] [Includes: Lactose synthase A protein (EC 2.4.1.22); N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)]B4galt1 Ggtb Ggtb2P155357
Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (BRK-3) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)Bmpr2O356077
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (BTB/POZ domain-containing protein TNFAIP1) (Tumor necrosis factor, alpha-induced protein 1, endothelial)Tnfaip1 Edp1O704797
C-C motif chemokine 9 (CCF18) (Macrophage inflammatory protein 1-gamma) (MIP-1-gamma) (Macrophage inflammatory protein-related protein 2) (MRP-2) (Small-inducible cytokine A9) [Cleaved into: CCL9(29-101); CCL9(30-101); CCL9(31-101)]Ccl9 Mrp2 Scya10 Scya9P516707
Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)Ppp3r1 CnbQ638107
Calcium-binding mitochondrial carrier protein Aralar1 (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12)Slc25a12 Aralar1Q8BH597
Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha)Camk1Q91YS87
Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)]Clstn1 Cs1 Cstn1 Kiaa0911Q9EPL27
cAMP-dependent protein kinase type II-alpha regulatory subunitPrkar2aP123677
Carbonic anhydrase 6 (EC 4.2.1.1) (Carbonate dehydratase VI) (Carbonic anhydrase VI) (CA-VI) (Salivary carbonic anhydrase) (Secreted carbonic anhydrase)Ca6 Car6P187617
Cartilage oligomeric matrix protein (COMP)CompQ9R0G67
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)Csnk1eQ9JMK27
Cathepsin G (EC 3.4.21.20) (Vimentin-specific protease) (VSP)CtsgP282937
Cbx3 protein (Chromobox protein homolog 3) (MCG119115, isoform CRA_a) (Putative uncharacterized protein)Cbx3 mCG_119115Q9DCC57
CD177 antigen (CD antigen CD177)Cd177Q8R2S87
CD276 antigen (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276)Cd276 B7h3Q8VE987
Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2)Cadm4 Igsf4c Necl4 Tsll2Q8R4647
Cell division cycle protein 16 homolog (Anaphase-promoting complex subunit 6) (APC6) (Cyclosome subunit 6)Cdc16 Anapc6Q8R3497
Cellular nucleic acid-binding protein (CNBP) (Zinc finger protein 9)Cnbp Cnbp1 Znf9P539967
Chitinase-like protein 3 (EC 3.2.1.52) (Beta-N-acetylhexosaminidase Ym1) (Chitinase-3-like protein 3) (ECF-L) (Eosinophil chemotactic cytokine) (Secreted protein Ym1)Chil3 Chi3l3 Ym1O357447
Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Proteoglycan AN2)Cspg4 An2 Kiaa4232 Ng2Q8VHY07
Chromosome-associated kinesin KIF4 (Chromokinesin)Kif4 Kif4a Kns4P331747
Coiled-coil domain-containing protein 93Ccdc93Q7TQK57
Collagen alpha-1(III) chainCol3a1P081217
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