EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Type 2 lactosamine alpha-2,3-sialyltransferase (EC 2.4.99.-) (CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI) (ST3Gal VI) (ST3GalVI) (Sialyltransferase 10)St3gal6 Siat10Q8VIB36
Tyrosine-protein kinase BAZ1B (EC 2.7.10.2) (Bromodomain adjacent to zinc finger domain protein 1B) (Williams syndrome transcription factor homolog) (Williams-Beuren syndrome chromosomal region 9 protein homolog)Baz1b Wbscr9 WstfQ9Z2776
Tyrosine-protein kinase FRK (EC 2.7.10.2) (Beta-cell Src-homology tyrosine kinase) (BSK) (FYN-related kinase) (Intestine tyrosine kinase)Frk Bsk IykQ922K96
U4/U6.U5 tri-snRNP-associated protein 2 (Inactive ubiquitin-specific peptidase 39)Usp39Q3TIX96
U6 snRNA-associated Sm-like protein LSm8Lsm8Q6ZWM46
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)Usp10 Kiaa0190 Ode-1 UchrpP524796
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)Usp8 Kiaa0055 UbpyQ80U876
Ubiquitin thioesterase OTUB1Otub1D3YWF66
Ubiquitin-associated protein 2-likeUbap2lQ80X506
Ubiquitin-like protein ISG15 (Interferon-induced 15 kDa protein) (Interferon-induced 17 kDa protein) (IP17) (Ubiquitin cross-reactive protein)Isg15 G1p2 UcrpQ643396
Ubiquitinyl hydrolase 1 (EC 3.4.19.12)Usp5Q3U4W86
Uncharacterized proteinGm9493F6SVV16
Unconventional myosin-IfMyo1fP702486
Unconventional myosin-IXbMyo9bE9PZW86
Unconventional myosin-VIIaMyo7a Myo7P974796
Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37)UrodP706976
Vacuolar protein sorting-associated protein 37A (Vps37A) (ESCRT-I complex subunit VPS37A)Vps37aQ8CHS86
Vacuolar protein sorting-associated protein 51 homolog (Protein fat-free homolog)Vps51 FfrQ3UVL46
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (EC 1.3.8.9) (MVLCAD) (VLCAD)Acadvl VlcadP505446
Vinexin (SH3 domain-containing protein SH3P3) (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)Sorbs3 Scam1 Sh3d4Q9R1Z86
Voltage-dependent anion-selective channel protein 2 (Fragment)Vdac2G3UX266
WD repeat-containing protein 18Wdr18Q4VBE86
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]Smu1Q3UKJ76
Wiskott-Aldrich syndrome protein family member 1 (WASP family protein member 1) (Protein WAVE-1)Wasf1 Wave1Q8R5H66
Zinc finger CCCH-type antiviral protein 1Zc3hav1D3Z5I16
Zinc finger RNA-binding proteinZfrO885326
Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein)Azgp1Q647266
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD) (Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1) (MTCBP-1)Adi1 Mtcbp1Q99JT95
2',5'-phosphodiesterase 12 (2'-PDE) (2-PDE) (EC 3.1.4.-) (Mitochondrial deadenylase) (EC 3.1.13.4)Pde12Q3TIU45
2'-5'-oligoadenylate synthase 1A ((2-5')oligo(A) synthase 1A) (2-5A synthase 1A) (EC 2.7.7.84) (p42 OAS)Oas1a Oias1P119285
2'-5'-oligoadenylate synthase 3 ((2-5')oligo(A) synthase 3) (2-5A synthase 3) (EC 2.7.7.84) (2',5'-oligoadenylate synthetase-like 10)Oas3 oasl10Q8VI935
26S protease regulatory subunit 6APsmc3A2AGN75
28S ribosomal protein S27, mitochondrial (MRP-S27) (S27mt)Mrps27Q8BK725
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) (EC 1.1.1.31)HibadhQ99L135
39S ribosomal protein L4, mitochondrial (L4mt) (MRP-L4)Mrpl4 MNCb-3848Q9DCU65
40S ribosomal protein S28 (Fragment)Rps28G3UYV75
5'-AMP-activated protein kinase subunit gamma-2 (AMPK gamma2) (AMPK subunit gamma-2)Prkag2Q91WG55
7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Sterol Delta(7)-reductase)Dhcr7O884555
A-kinase anchor protein 12 (AKAP-12) (Germ cell lineage protein gercelin) (Src-suppressed C kinase substrate) (SSeCKS)Akap12 Gag12 SsecksQ9WTQ55
Actin-related protein 2/3 complex subunit 1A (SOP2-like protein) (Sid 329)Arpc1a Sid329Q9R0Q65
Activating signal cointegrator 1 complex subunit 2 (ASC-1 complex subunit p100) (Trip4 complex subunit p100)Ascc2 Asc1p100Q91WR35
Acyl-coenzyme A thioesterase 1 (Acyl-CoA thioesterase 1) (EC 3.1.2.2) (CTE-I) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase)Acot1 Cte1O551375
Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase); Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)]Mocs3 Uba4A2BDX35
ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2)Gga2 Kiaa1080Q6P5E65
AfadinAfdnE9Q8525
Aflatoxin B1 aldehyde reductase member 2 (EC 1.1.1.n11) (Succinic semialdehyde reductase) (SSA reductase)Akr7a2 Afar Akr7a5Q8CG765
AgrinAgrnM0QWP15
AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein)AipO089155
AHNAK nucleoprotein 2 (Fragment)Ahnak2F7DBB35
Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Alkylglycerone-phosphate synthase)AgpsQ8C0I15
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.101) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I) (GNT-I) (GlcNAc-T I)Mgat1 Gnt1P278085
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb) (GlcNAc-T IVb) (GnT-IVb) (N-acetylglucosaminyltransferase IVb) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb)Mgat4bQ812F85
Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2 homolog) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)Alg2 MNCb-5081Q9DBE85
Alpha-2-antiplasmin (Alpha-2-AP) (Alpha-2-plasmin inhibitor) (Alpha-2-PI) (Serpin F2)Serpinf2 PliQ612475
Alpha-amylase 1 (EC 3.2.1.1) (1,4-alpha-D-glucan glucanohydrolase 1) (Salivary and hepatic alpha-amylase)Amy1 Amy-1-a Amy1aP006875
Alpha-parvin (Putative uncharacterized protein)ParvaQ3UF755
Alsin (Amyotrophic lateral sclerosis 2 protein homolog)Als2Q920R05
Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase)Ppat mCG_15865Q8CIH95
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Putative uncharacterized protein)Aimp1 Scye1Q3UZG45
Aminopeptidase BRnpepE9PYF15
AMP deaminase 2 (EC 3.5.4.6) (AMP deaminase isoform L)Ampd2Q9DBT55
Amyloid-like protein 2 (APLP-2) (CDEI box-binding protein) (CDEBP)Aplp2Q063355
Angiotensinogen (Serpin A8) [Cleaved into: Angiotensin-1 (Angiotensin 1-10) (Angiotensin I) (Ang I); Angiotensin-2 (Angiotensin 1-8) (Angiotensin II) (Ang II); Angiotensin-3 (Angiotensin 2-8) (Angiotensin III) (Ang III) (Des-Asp[1]-angiotensin II); Angiotensin-4 (Angiotensin 3-8) (Angiotensin IV) (Ang IV); Angiotensin 1-9; Angiotensin 1-7; Angiotensin 1-5; Angiotensin 1-4]Agt Serpina8P118595
Ankyrin-1 (ANK-1) (Erythrocyte ankyrin)Ank1 Ank-1Q023575
Apolipoprotein A-II (Apo-AII) (ApoA-II) (Apolipoprotein A2) [Cleaved into: Proapolipoprotein A-II (ProapoA-II)]Apoa2P098135
Apolipoprotein C-I (Apo-CI) (ApoC-I) (Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I]Apoc1P349285
Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein)Pycard AscQ9EPB45
Apoptotic chromatin condensation inducer in the nucleus (Acinus)Acin1 AcinusQ9JIX85
Aquaporin-5 (AQP-5)Aqp5Q9WTY45
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1)Git1Q68FF65
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3) (CRAM-associated GTPase) (CRAG) (Centaurin-gamma-3) (Cnt-g3) (MR1-interacting protein) (MRIP-1)Agap3 Centg3Q8VHH55
Arginine and glutamate-rich protein 1Arglu1Q3UL365
AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1)Arid1a Baf250 Baf250a Osa1 Smarcf1A2BH405
Ataxin-2 (Fragment)Atxn2F6U2C25
Atlastin-2 (EC 3.6.5.-) (ADP-ribosylation factor-like protein 6-interacting protein 2) (ARL-6-interacting protein 2) (Aip-2)Atl2 Arl6ip2Q6PA065
ATP-binding cassette sub-family A member 7Abca7Q91V245
ATP-binding cassette sub-family F member 3Abcf3Q8K2685
ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase)Naxd CarkdQ9CZ425
ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)ClppO886965
ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2)Ddx50Q99MJ95
Atrial natriuretic peptide receptor 2 (EC 4.6.1.2) (Atrial natriuretic peptide receptor type B) (ANP-B) (ANPR-B) (NPR-B) (Guanylate cyclase B) (GC-B)Npr2Q6VVW55
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis)Bag3 Bis MNCb-2243Q9JLV15
Band 4.1-like protein 1Epb41l1 Epb4.1l1A2AUK75
Band 4.1-like protein 4A (Protein NBL4)Epb41l4a Epb4.1l4 Epb4.1l4a Epb41l4P529635
Basal cell adhesion molecule (B-CAM cell surface glycoprotein) (Lutheran antigen) (CD antigen CD239)Bcam Gplu LuQ9R0695
Beta-1,4 N-acetylgalactosaminyltransferase 1 (EC 2.4.1.92) ((N-acetylneuraminyl)-galactosylglucosylceramide) (GM2/GD2 synthase) (GalNAc-T)B4galnt1 Galgt Galgt1 Ggm2Q092005
Beta-globin (Globin a1) (Hemoglobin, beta adult s chain) (Hemoglobin, beta adult t chain)Hbbt1 Glna1 Hbb-bs Hbb-bt Hbbt2A8DUK45
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phosphatidylserine receptor) (Protein PTDSR)Jmjd6 Kiaa0585 PtdsrQ9ERI55
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)]Gne Glcne Uae1Q91WG85
Bin1 protein (Myc box-dependent-interacting protein 1)Bin1Q6P1B95
Brain-specific angiogenesis inhibitor 1-associated protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2, isoform CRA_c)Baiap2 mCG_15032B1AZ465
Branched-chain-amino-acid aminotransferase, cytosolic (BCAT(c)) (EC 2.6.1.42) (Protein ECA39)Bcat1 Eca39P242885
BRCA1-A complex subunit BRE (BRCA1/BRCA2-containing complex subunit 45) (Brain and reproductive organ-expressed protein)BreQ8K3W05
Bromodomain-containing protein 9Brd9Q3UQU05
C-Jun-amino-terminal kinase-interacting protein 4 (JIP-4) (JNK-interacting protein 4) (JNK-associated leucine-zipper protein) (JLP) (JNK/SAPK-associated protein 2) (JSAP2) (Mitogen-activated protein kinase 8-interacting protein 4) (Sperm-associated antigen 9)Spag9 Jip4 Jsap2 Kiaa0516 Mapk8ip4Q58A655
Cadherin 19, type 2Cdh19E9Q3A75
Calcium homeostasis endoplasmic reticulum protein (SR-related CTD-associated factor 6)Cherp Scaf6Q8CGZ05
Calcium-activated chloride channel regulator 1 (EC 3.4.-.-) (Calcium-activated chloride channel family member 3) (mCLCA3) (Protein gob-5)Clca1 Clca3 Gob5Q9D7Z65
Calcium-binding protein 39-like (MO25beta) (Mo25-like protein)Cab39lQ9DB165
Calcium-transporting ATPase (EC 3.6.3.8)Atp2b3Q0VF555
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