EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Fatty aldehyde dehydrogenase (EC 1.2.1.3) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A2)Aldh3a2 Ahd-3 Ahd3 Aldh3 Aldh4P477405
Fermitin family homolog 1 (Kindlin-1) (Unc-112-related protein 1)Fermt1 Kind1 Urp1P591135
Ficolin-1 (Collagen/fibrinogen domain-containing protein 1) (Ficolin-A) (Ficolin-alpha) (M-ficolin)Fcn1 FcnaO701655
Formin-binding protein 1 (Formin-binding protein 17)Fnbp1 Fbp17 Kiaa0554Q80TY05
Galectin-8 (Gal-8) (LGALS-8)Lgals8Q9JL155
Glia maturation factor gamma (GMF-gamma)GmfgQ9ERL75
Glucose-6-phosphate exchanger SLC37A2 (Solute carrier family 37 member 2) (cAMP-inducible protein 2)Slc37a2 Ci2Q9WU815
Glucoside xylosyltransferase 2 (EC 2.4.2.n2) (Glycosyltransferase 8 domain-containing protein 4)Gxylt2 Glt8d4Q810K95
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 (EC 2.6.1.16) (D-fructose-6-phosphate amidotransferase 2) (Glutamine:fructose-6-phosphate amidotransferase 2) (GFAT 2) (GFAT2) (Hexosephosphate aminotransferase 2)Gfpt2Q9Z2Z95
Glutathione S-transferase P 2 (Gst P2) (EC 2.5.1.18) (GST YF-YF) (GST class-pi) (GST-piA)Gstp2 GstpiaP464255
Glycerol kinase (GK) (Glycerokinase) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase)Gk GykQ645165
Glycerol-3-phosphate dehydrogenase, mitochondrial (GPD-M) (GPDH-M) (EC 1.1.5.3) (Protein TISP38)Gpd2 Gdm1Q645215
Glycosylated lysosomal membrane protein (Lysosomal protein NCU-G1)GlmpQ9JHJ35
GMP reductase 1 (GMPR 1) (EC 1.7.1.7) (Guanosine 5'-monophosphate oxidoreductase 1) (Guanosine monophosphate reductase 1)Gmpr Gmpr1Q9DCZ15
Golgi autoantigen, golgin subfamily b, macrogolgin 1Golgb1E9QAH15
Golgi reassembly-stacking protein 2 (GRS2) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55)Gorasp2Q99JX35
GTP-binding nuclear protein Ran, testis-specific isoformRasl2-9Q618205
GTP-binding protein SAR1aSar1a Sara Sara1P365365
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7Gng7 Gngt7Q610165
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2Gnb2E9QKR05
H-2 class I histocompatibility antigen, D-K alpha chain (H-2D(K))H2-D1P144265
Helicase with zinc finger domain 2 (EC 3.6.4.-) (PPAR-gamma DNA-binding domain-interacting protein 1) (PDIP1) (PPAR-gamma DBD-interacting protein 1)Helz2E9QAM55
Heme oxygenase 2 (HO-2) (EC 1.14.14.18)Hmox2O702525
Hepatocyte growth factor-regulated tyrosine kinase substrateHgsB1ATZ05
Heterogeneous nuclear ribonucleoprotein A3Hnrnpa3A2AL125
Heterogeneous nuclear ribonucleoprotein H (Putative uncharacterized protein)Hnrnph1 Hnrph1Q8C2Q75
Heterogeneous nuclear ribonucleoprotein U (Heterogeneous nuclear ribonucleoprotein U, isoform CRA_b)Hnrnpu Gm28062 Hnrpu mCG_17220G3XA105
High affinity cationic amino acid transporter 1 (Fragment)Slc7a1E9Q3N15
Histocompatibility 2, Q region locus 4 (Putative uncharacterized protein)H2-Q4 H2-Gs10 H2-gs10 H2-Q1Q8HWB25
Histone H3H3f3aF8WI355
Histone-lysine N-methyltransferase setd3 (EC 2.1.1.43) (Endothelial differentiation inhibitory protein D10) (SET domain-containing protein 3)Setd3 D12Ertd771eQ91WC05
Huntingtin (Huntington disease protein homolog) (HD protein homolog)Htt Hd HdhP428595
Hyaluronan and proteoglycan link protein 1 (Cartilage-linking protein 1) (Cartilage-link protein) (Proteoglycan link protein)Hapln1 Crtl1Q9QUP55
Hyaluronan synthase 1 (EC 2.4.1.212) (Hyaluronate synthase 1) (Hyaluronic acid synthase 1) (HA synthase 1)Has1 HasQ616475
Ig heavy chain V region 1-62-3 (Ig heavy chain V region 145)Ighv1-62-3 Igh-VJ558P017545
Ig heavy chain V region 6.960P185285
Ig heavy chain V region M5110P017905
Ig heavy chain V region MOPC 47A0P017865
Ig heavy chain V-III region ABE-47N0P017995
Ig heavy chain V-III region T9570P018005
Ig kappa chain V-III region 50S10.10P039775
Ig lambda-1 chain C region0P018435
Ig lambda-2 chain C regionIglc2P018445
Ig lambda-3 chain C regionIglc3P018455
Influenza virus NS1A-binding protein homolog (NS1-BP) (NS1-binding protein homolog) (Kelch family protein Nd1-L) (ND1-L2) (Nd1-S)Ivns1abp Kiaa0850 Nd1 Nd1L Nd1S Ns1 Ns1bpQ920Q85
Inhibitor of carbonic anhydraseIcaQ9DBD05
Inositol monophosphatase 2 (IMP 2) (IMPase 2) (EC 3.1.3.25) (Inositol-1(or 4)-monophosphatase 2) (Myo-inositol monophosphatase A2)Impa2Q91UZ55
Inositol polyphosphate-5-phosphatase A (Inpp5a protein) (Putative uncharacterized protein)Inpp5aQ7TNC95
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)Igf2bp1 Vickz1O884775
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)Igf2bp2 Imp2 Vickz2Q5SF075
Insulin-like growth factor-binding protein 3 (IBP-3) (IGF-binding protein 3) (IGFBP-3)Igfbp3 Igfbp-3P478785
Integrator complex subunit 1 (Int1)Ints1Q6P4S85
Integrin alpha-VItgavA2AKI55
Integrin beta-6Itgb6Q9Z0T95
Interferon-activable protein 204 (Ifi-204) (Interferon-inducible protein p204)Ifi204P0DOV25
Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4) (TPA-induced sequence 7) (TIS7 protein)Ifrd1 Tis7P191825
Interferon-related developmental regulator 2 (Putative uncharacterized protein)Ifrd2 mCG_18874Q9D8U05
Intersectin-1 (EH and SH3 domains protein 1)Itsn1 Ese1 ItsnQ9Z0R45
Intron-binding protein aquariusAqr Kiaa0560Q8CFQ35
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2)Keap1 Inrf2 Kiaa0132Q9Z2X85
Keratin, type I cytoskeletal 10Krt10A2A5135
Keratin, type II cuticular Hb4 (65 kDa type II keratin) (Keratin-84) (K84) (Type II hair keratin Hb4) (Type-II keratin Kb24)Krt84 Krt2-16 Krthb4Q99M735
Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK-6B) (Keratin-6-beta) (mK6-beta) (Keratin-6B) (K6B)Krt6b K6-beta Krt2-6bQ9Z3315
Keratin, type II cytoskeletal 6B (Putative uncharacterized protein)Krt6b Krt2-6bQ3UV115
Keratin, type II cytoskeletal 72 (Cytokeratin-72) (CK-72) (Keratin-72) (K72) (Type II inner root sheath-specific keratin-K6irs2) (Type-II keratin Kb35)Krt72 Kb35 Krt72-psQ6IME95
Kinesin light chain 2 (KLC 2)Klc2O884485
Kinesin-associated protein 3 (KAP-3) (KAP3)Kifap3P701885
Kinesin-like protein KIF11 (Kinesin-related motor protein Eg5)Kif11Q6P9P65
Kinesin-like protein KIF15 (Kinesin-like protein 2) (Kinesin-like protein 7)Kif15 Klp2 Knsl7Q6P9L65
Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)Kif3a Kif3P287415
Kinesin-like protein KIF3B (Microtubule plus end-directed kinesin motor 3B) [Cleaved into: Kinesin-like protein KIF3B, N-terminally processed]Kif3bQ617715
Kinesin-like protein KIF3CKif3cO350665
L-lactate dehydrogenase C chain (LDH-C) (EC 1.1.1.27) (LDH testis subunit) (LDH-X)Ldhc Ldh-3 Ldh3P003425
Laminin subunit beta-1Lamb1E9QN705
Latent-transforming growth factor beta-binding protein 4 (LTBP-4)Ltbp4Q8K4G15
Leukocyte immunoglobulin-like receptor subfamily B member 4 (Mast cell surface glycoprotein Gp49B) (CD antigen CD85k)Lilrb4 Gp49bQ642815
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)DbtP533955
Low-density lipoprotein receptor-related protein 6 (LRP-6)Lrp6O885725
Lymphocyte-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein)Hells Lsh PasgQ608485
Lysosomal-associated transmembrane protein 4A (Golgi 4-transmembrane-spanning transporter) (Mouse transporter protein) (MTP)Laptm4a MtrpQ609615
Macrophage erythroblast attacher (Erythroblast macrophage protein)Maea EmpQ4VC335
Macrophage scavenger receptor types I and II (Macrophage acetylated LDL receptor I and II) (Scavenger receptor type A) (SR-A) (CD antigen CD204)Msr1 ScvrP302045
Macrophage-capping protein (Actin regulatory protein CAP-G) (Actin-capping protein GCAP39) (Myc basic motif homolog 1)Capg Mbh1P244525
MAGUK p55 subfamily member 7 (MCG5292, isoform CRA_d)Mpp7 mCG_5292G5E8S85
MAM domain-containing protein 2 (MAM domain-containing proteoglycan) (Mamcan)Mamdc2Q8CG855
Mannosyl-oligosaccharide glucosidase (EC 3.2.1.106) (Glucosidase 1) (Glycoprotein-processing glucosidase I)Mogs Gcs1Q80UM75
MAP kinase-activated protein kinase 2 (MAPK-activated protein kinase 2) (MAPKAP kinase 2) (MAPKAP-K2) (MAPKAPK-2) (MK-2) (MK2) (EC 2.7.11.1)Mapkapk2 Rps6kc1P491385
MAP7 domain-containing protein 1Map7d1 Kiaa1187 Mtap7d1A2AJI05
Matrix Gla protein (MGP)Mgp MglapP197885
MCG4375, isoform CRA_b (Putative uncharacterized protein) (Syntenin-1)Sdcbp mCG_4375Q3TMX05
MCG48959 (Peroxiredoxin 6, related sequence 1) (Peroxiredoxin 6B) (Putative uncharacterized protein)Prdx6b Prdx6-ps1 Prdx6-rs1 Prdx6-rs1-ps mCG_48959Q8BG375
MCG6846, isoform CRA_c (Phosphoribosyl pyrophosphate synthase-associated protein 1)Prpsap1 mCG_6846B1AT825
Membrane primary amine oxidase (EC 1.4.3.21) (Copper amine oxidase) (Semicarbazide-sensitive amine oxidase) (SSAO) (Vascular adhesion protein 1) (VAP-1)Aoc3 Vap1O704235
Mesothelin (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form]Msln Mes MpfQ614685
Metalloproteinase inhibitor 2 (Timp2 protein) (Tissue inhibitor of metalloproteinase 2)Timp2 mCG_140800Q6PI175
Metalloreductase STEAP1 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 1)Steap1 SteapQ9CWR75
Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2)Mbd2Q9Z2E15
Methyltransferase-like protein 13 (EC 2.1.1.-)Mettl13 Kiaa0859Q91YR55
Microfibril-associated glycoprotein 4Mfap4Q9D1H95
Microsomal glutathione S-transferase 1 (Microsomal GST-1) (EC 2.5.1.18) (Microsomal GST-I)Mgst1Q91VS75
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