EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
D-beta-hydroxybutyrate dehydrogenase, mitochondrial (EC 1.1.1.30) (3-hydroxybutyrate dehydrogenase) (BDH)Bdh1 BdhQ80XN04
DBF4-type zinc finger-containing protein 2 homologZdbf2Q5SS004
DCN1-like protein 3 (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3)Dcun1d3Q8K0V24
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)Dcaf7 Han11 Wdr68P619634
Dedicator of cytokinesis protein 10Dock10E9QM994
Dedicator of cytokinesis protein 6Dock6E9QPN74
Dedicator of cytokinesis protein 7Dock7A2A9M54
Dedicator of cytokinesis protein 9Dock9F8VPN74
Dehydrogenase/reductase SDR family member 4 (EC 1.1.1.184) (NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase) (CR) (PHCR) (NADPH-dependent retinol dehydrogenase/reductase) (NDRD) (mouNRDR) (Peroxisomal short-chain alcohol dehydrogenase) (PSCD)Dhrs4 D14Ucla2Q99LB24
Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol delta-24-reductase)Dhcr24 Kiaa0018Q8VCH64
Delta-sarcoglycan (Delta-SG) (35 kDa dystrophin-associated glycoprotein) (35DAG)SgcdP823474
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1Samhd1E9Q0K64
Deoxyribonuclease-2-beta (EC 3.1.22.1) (DNase II-like acid DNase) (DNase2-like acid DNase) (Deoxyribonuclease II beta) (DNase II beta) (Endonuclease DLAD)Dnase2b DladQ9QY484
Dephospho-CoA kinase domain-containing proteinDcakdQ8BHC44
Dihydropteridine reductaseQdprD3YWR74
Dihydropyrimidinase-related protein 3 (Putative uncharacterized protein)Dpysl3Q3TT924
Dipeptidase 1 (EC 3.4.13.19) (Membrane-bound dipeptidase 1) (MBD-1) (Microsomal dipeptidase) (Renal dipeptidase)Dpep1 Mbd1 RdpP314284
Dipeptidyl peptidase 9 (DP9) (EC 3.4.14.5) (Dipeptidyl peptidase IX) (DPP IX) (Dipeptidyl peptidase-like protein 9) (DPLP9)Dpp9Q8BVG44
Disco-interacting protein 2 homolog ADip2aF8WI564
Discoidin, CUB and LCCL domain-containing protein 2 (Endothelial and smooth muscle cell-derived neuropilin-like protein)Dcbld2 EsdnQ91ZV34
Disintegrin and metalloproteinase domain-containing protein 17Adam17E9PXU24
DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA)Dnmt3aO885084
DNA mismatch repair protein Msh6 (G/T mismatch-binding protein) (GTBP) (GTMBP) (MutS protein homolog 6) (MutS-alpha 160 kDa subunit) (p160)Msh6 GtmbpP542764
DNA primase large subunit (EC 2.7.7.-) (DNA primase 58 kDa subunit) (p58)Prim2P336104
DNA primase small subunit (EC 2.7.7.-) (DNA primase 49 kDa subunit) (p49)Prim1P206644
DNA repair protein RAD50 (RAD50 homolog (S. cerevisiae))Rad50 mCG_119249Q5SV024
DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1)Xrcc1 Xrcc-1Q605964
DNA segment, Chr 15, Wayne State University 169, expressed, isoform CRA_a (Rho GTPase-activating protein 39)Arhgap39 D15Wsu169e mCG_134448G3X9324
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (p460)Prkdc Xrcc7P973134
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)Polr3bP594704
DnaJ homolog subfamily B member 2 (DnaJ homolog subfamily B member 10) (mDj8)Dnajb2 Dnajb10Q9QYI54
DnaJ homolog subfamily C member 2 (Mouse Id associate 1) (MIDA1) (Zuotin-related factor 1) [Cleaved into: DnaJ homolog subfamily C member 2, N-terminally processed]Dnajc2 Mida1 Zrf1P541034
DnaJ homolog subfamily C member 8Dnajc8Q6NZB04
DnaJ homolog subfamily C member 9Dnajc9Q91WN14
Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok))Dok1 DokP974654
Dolichol-phosphate mannosyltransferase subunit 1 (EC 2.4.1.83) (Dolichol-phosphate mannose synthase subunit 1) (DPM synthase subunit 1) (Dolichyl-phosphate beta-D-mannosyltransferase subunit 1) (Mannose-P-dolichol synthase subunit 1) (MPD synthase)Dpm1O701524
Drebrin (Developmentally-regulated brain protein)Dbn1 DrbaQ9QXS64
Dynactin subunit 3Dctn3E9Q9194
Dynamin-1 (EC 3.6.5.5)Dnm1 Dnm Kiaa4093P390534
Dynamin-2 (Putative uncharacterized protein)Dnm2Q3TCR74
Dynein heavy chain 5, axonemal (Axonemal beta dynein heavy chain 5) (mDNAH5) (Ciliary dynein heavy chain 5)Dnah5 Dnahc5Q8VHE64
Dynein light chain roadblockDynlrb1A2AVR94
DystrobrevinDtnbG3UY344
E3 ubiquitin-protein ligase listerin (EC 2.3.2.27) (RING finger protein 160) (RING-type E3 ubiquitin transferase listerin) (Zinc finger protein 294) (Zfp-294)Ltn1 Kiaa0714 Lister Rnf160 Zfp294 Znf294Q6A0094
E3 ubiquitin-protein ligase makorin-1Mkrn1E9QAG74
E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase makorin-1)Mkrn1Q9QXP64
E3 ubiquitin-protein ligase NEDD4-likeNedd4lE9PXB74
E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase pellino homolog 1)Peli1Q8C6694
E3 ubiquitin-protein ligase RBX1 (EC 6.3.2.-) (RING finger protein 75) (RING-box protein 1) (Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed]Rbx1P628784
E3 ubiquitin-protein ligase RNF128 (EC 2.3.2.27) (Gene related to anergy in lymphocytes protein) (Goliath-related E3 ubiquitin-protein ligase 1) (RING finger protein 128) (RING-type E3 ubiquitin transferase RNF128)Rnf128 Grail Greul1 MNCb-3816Q9D3044
E3 ubiquitin-protein ligase TRIM33 (EC 2.3.2.27) (Ectodermin homolog) (RING-type E3 ubiquitin transferase TRIM33) (Transcription intermediary factor 1-gamma) (TIF1-gamma) (Tripartite motif-containing protein 33)Trim33 Kiaa1113Q99PP74
E3 ubiquitin-protein ligase TRIM56 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM56) (Tripartite motif-containing protein 56)Trim56Q80VI14
E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (N-recognin-2) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3-alpha-2) (Ubiquitin-protein ligase E3-alpha-II)Ubr2 Kiaa0349Q6WKZ84
E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog)Ubr5 Edd Edd1 Kiaa0896Q80TP34
Ectonucleoside triphosphate diphosphohydrolase 3 (Nucleoside triphosphate diphosphohydrolase-3) (EC 3.6.1.5) (Putative uncharacterized protein)Entpd3 mCG_22707Q8BFW64
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (E-NPP 3) (Phosphodiesterase I beta) (PD-Ibeta) (Phosphodiesterase I/nucleotide pyrophosphatase 3) (CD antigen CD203c) [Includes: Alkaline phosphodiesterase I (EC 3.1.4.1); Nucleotide pyrophosphatase (NPPase) (EC 3.6.1.9) (Nucleotide diphosphatase)]Enpp3Q6DYE84
Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na+-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3)Slc4a8 Kiaa0739Q8JZR64
Ellis-van Creveld syndrome protein homologEvcD3YUJ04
Elongation factor 1-delta (Fragment)Eef1dE9QN084
Elongator complex protein 4 (PAX6 neighbor gene protein)Elp4 PaxnebQ9ER734
Elongin-A (EloA) (Elongin 110 kDa subunit) (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Transcription elongation factor B polypeptide 3)Eloa Tceb3Q8CB774
Endonuclease domain-containing 1 protein (EC 3.1.30.-)Endod1 Kiaa0830Q8C5224
Endophilin-B2 (SH3 domain-containing GRB2-like protein B2)Sh3glb2 Kiaa1848Q8R3V54
Enhancer of mRNA-decapping protein 3 (YjeF domain-containing protein 1)Edc3 YjdcQ8K2D34
Enhancer of rudimentary homolog (MCG7617, isoform CRA_a)Erh mCG_7617G3UW854
Enoyl-[acyl-carrier-protein] reductase, mitochondrial (EC 1.3.1.104) (2-enoyl thioester reductase) (Nuclear receptor-binding factor 1) (NRBF-1)Mecr Nrbf1Q9DCS34
Eph receptor A7, isoform CRA_b (Ephrin type-A receptor 7)Epha7 mCG_14600A2BDQ44
Ephrin type-A receptor 1 (mEpha1) (EC 2.7.10.1) (Embryonic stem cell kinase) (Tyrosine-protein kinase receptor ESK)Epha1 EskQ607504
Ephrin type-B receptor 4 (Putative uncharacterized protein)Ephb4Q8C8K14
Epidermal growth factor receptor substrate 15-like 1 (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs) (Eps15-related protein) (Eps15R)Eps15l1 Eps15-rs Eps15RQ609024
Epoxide hydrolase (EC 3.3.2.9)Ephx1E9PWK14
Epsin-1 (EPS-15-interacting protein 1) (Intersectin-EH-binding protein 1) (Ibp1)Epn1Q80VP14
Equilibrative nucleoside transporter 3 (mENT3) (Solute carrier family 29 member 3)Slc29a3 Ent3Q99P654
ER membrane protein complex subunit 1Emc1 Kiaa0090Q8C7X24
ER membrane protein complex subunit 3 (Transmembrane protein 111)Emc3 Tmem111Q99KI34
ERC protein 2 (CAZ-associated structural protein 1) (CAST1)Erc2 Cast1 D14Ertd171e Kiaa0378Q6PH084
Eukaryotic translation initiation factor 1A (eIF-1A) (Eukaryotic translation initiation factor 4C) (eIF-4C)Eif1aQ608724
Exosome complex component RRP43 (Exosome component 8) (Ribosomal RNA-processing protein 43)Exosc8 Rrp43Q9D7534
Exosome complex component RRP46 (Exosome component 5) (Ribosomal RNA-processing protein 46)Exosc5 D7Wsu180e Rrp46Q9CRA84
Exosome complex exonuclease RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42)Exosc7 Rrp42Q9D0M04
Exosome component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2 homolog) (Polymyositis/scleroderma autoantigen 2 homolog)Exosc10 Pmscl2P569604
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)Tbl1xr1 Ira1 Tblr1Q8BHJ54
F-box/WD repeat-containing protein 1A (Beta-TrCP protein E3RS-IkappaB) (Beta-transducin repeat-containing protein) (Beta-TrCP) (E3RSIkappaB) (mE3RS-IkappaB) (F-box and WD repeats protein beta-TrCP) (HOS) (Ubiquitin ligase FWD1) (pIkappaB-E3 receptor subunit)Btrc Fbw1 Fbxw1 Fwd1 Kiaa4123Q3ULA24
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8)Fbxw8Q8BIA44
Family with sequence similarity 171, member A1Fam171a1A2ATL04
Far upstream element-binding protein 1 (Putative uncharacterized protein)Fubp1Q3TUE14
FERM, RhoGEF and pleckstrin domain-containing protein 2Farp2D3Z4C04
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (Keratinocyte growth factor receptor) (KGFR) (CD antigen CD332)Fgfr2 Bek Ect1P218034
Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (FRS2-alpha) (Suc1-associated neurotrophic factor target 1) (SNT-1)Frs2 Frs2aQ8C1804
Follistatin-related protein 1 (Follistatin-like protein 1) (TGF-beta-inducible protein TSC-36)Fstl1 Frp Fstl Tsc36Q623564
Formin-like protein 2Fmnl2F8VPR24
Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator) (TP53-induced glycolysis regulatory phosphatase)TigarQ8BZA94
Fructose-bisphosphate aldolase (EC 4.1.2.13)Aldoart2A6ZI474
FRY-like transcription coactivatorFrylF8VQ054
G-protein-signaling modulator 2 (Pins homolog)Gpsm2 Lgn PinsQ8VDU04
G2/mitotic-specific cyclin-B1Ccnb1 Ccn-2 Ccnb1-rs13 Cycb Cycb1P248604
Gag protein0Q6YIY04
Gamma-aminobutyric acid receptor-associated protein-like 1 (GABA(A) receptor-associated protein-like 1) (Glandular epithelial cell protein 1) (GEC-1)Gabarapl1 Apg8l Atg8l Gec1 MNCb-0091Q8R3R84
Gamma-glutamyltransferase 7 (GGT 7) (EC 2.3.2.2) (Gamma-glutamyltransferase-like 3) (Gamma-glutamyltranspeptidase 7) (Glutathione hydrolase 7) (EC 3.4.19.13) [Cleaved into: Gamma-glutamyltransferase 7 heavy chain; Gamma-glutamyltransferase 7 light chain]Ggt7 Ggtl3Q99JP74
Gamma-soluble NSF attachment protein (Fragment)NapgD3Z4B24
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