EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Gap junction gamma-3 protein (Connexin-29) (Cx29) (Gap junction epsilon-1 protein)Gjc3 Cx29 Gje1Q921C14
Gem-associated protein 5Gemin5A2AFQ94
General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)Gtf3c1Q8K2844
General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BAP-135) (BTK-associated protein 135)Gtf2i Bap135 Diws1tQ9ESZ84
Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)]GphnQ8BUV34
Glutaminase kidney isoform, mitochondrial (GLS) (EC 3.5.1.2)Gls Gls1 Kiaa0838D3Z7P34
Glutaminyl-tRNA synthetase (Putative uncharacterized protein)QarsQ8BML94
Glycerophosphodiester phosphodiesterase domain-containing protein 1 (EC 3.1.-.-) (Glycerophosphodiester phosphodiesterase 4)Gdpd1 Gde4Q9CRY74
Glycogen phosphorylase, muscle form (EC 2.4.1.1) (Myophosphorylase)PygmQ9WUB34
Glycogen synthase kinase-3 alphaGsk3aD3Z7E54
Glycolipid transfer protein (GLTP)GltpQ9JL624
Golgi integral membrane protein 4Golim4D3YVW24
Golgi phosphoprotein 3 (Coat protein GPP34)Golph3 Gpp34Q9CRA54
Golgi resident protein GCP60 (Acyl-CoA-binding domain-containing protein 3) (Golgi complex-associated protein 1) (GOCAP1) (Golgi phosphoprotein 1) (GOLPH1) (PBR- and PKA-associated protein 7) (Peripheral benzodiazepine receptor-associated protein PAP7)Acbd3 Gcp60 Pap7Q8BMP64
Golgin subfamily A member 3 (Golgin-160) (Male-enhanced antigen 2) (MEA-2)Golga3 Mea2P559374
Granulins (Fragment)GrnH3BJE04
Granulins (Putative uncharacterized protein)GrnQ3U9N44
Growth factor receptor-bound protein 2Grb2B1AT924
GrpE protein homolog 1, mitochondrial (Mt-GrpE#1)Grpel1Q99LP64
GTP-binding nuclear protein Ran1700009N14Rik mCG_49183Q14AA64
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5Gng5 Gngt5Q80SZ74
Guanine nucleotide-binding protein G(olf) subunit alpha (Adenylate cyclase-stimulating G alpha protein, olfactory type)GnalQ8CGK74
Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortGnasZ4YKV14
Guanine nucleotide-binding protein G(t) subunit alpha-1 (Transducin alpha-1 chain)Gnat1 Gnat-1P206124
Guanine nucleotide-binding protein G(t) subunit alpha-3 (Gustducin alpha-3 chain)Gnat3Q3V3I24
Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (mGBP-2) (mGBP2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2)Gbp2Q9Z0E64
H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)Clcn7 Clc7O704964
H-2 class I histocompatibility antigen, K-D alpha chain (H-2K(D))H2-K1 H2-KP019024
H-2 class I histocompatibility antigen, TLA(B) alpha chain (Histocompatibility 2, T region locus 3) (MCG132399)H2-T3 mCG_132399Q05A754
H-2 class II histocompatibility antigen, A beta chainH2-Ab1 H2-iabetaP144834
HCLS1-binding protein 3 (HS1-binding protein 3) (HSP1BP-3)Hs1bp3Q3TC934
HEAT repeat containing 1 (HEAT repeat-containing 1)Heatr1 mCG_119362G3X9B14
Hematological and neurological expressed 1 protein [Cleaved into: Hematological and neurological expressed 1 protein, N-terminally processed]Hn1P978254
Hematological and neurological expressed 1-like protein (HN1-like protein)Hn1l D17Ertd441eQ6PGH24
Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain]HgfacQ9R0984
Hepatocyte growth factor-regulated tyrosine kinase substrate (Putative uncharacterized protein)HgsQ3UMA34
Heterogeneous nuclear ribonucleoprotein A1 (Putative uncharacterized protein)Hnrnpa1 Hnrpa1Q5EBP84
Heterogeneous nuclear ribonucleoprotein D-like (Fragment)Hnrnpdl Hnrnpdl1 HnrpdlF6VQH54
Heterogeneous nuclear ribonucleoprotein D0 (Fragment)HnrnpdE9Q5B64
Heterogeneous nuclear ribonucleoprotein KHnrnpk HnrpkB2M1R64
Heterogeneous nuclear ribonucleoprotein QSyncripG3UZI24
High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility group AT-hook protein 1) (High mobility group protein A1)Hmga1 Hmgi HmgiyP170954
High mobility group protein HMGI-C (High mobility group AT-hook protein 2)Hmga2 HmgicP529274
Histocompatibility 2, Q region locus 7 (MHC class Ib antigen)H2-Q9 H2-Q7Q52PG74
Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (Sin3-associated polypeptide p18)Sap18O551284
Histone lysine demethylase PHF8 (EC 1.14.11.27) (PHD finger protein 8)Phf8 Kiaa1111Q80TJ74
Huntingtin-interacting protein 1-related protein (HIP1-related protein)Hip1rQ9JKY54
Ig heavy chain V region MOPC 1730P018124
Ig kappa chain V-III region PC 3741/TEPC 1110P016604
Ig kappa chain V-III region PC 72100P016684
Immediate early response 3-interacting protein 1Ier3ip1Q9CR204
Immunity-related GTPase family M member 2 (Interferon-g induced GTPase) (Interferon-gamma-inducible GTPase Ifggd2 protein) (Putative uncharacterized protein)Irgm2 AI481100 GTPI Ifggd2 Iigp2Q9Z1M24
Importin subunit alpha-7 (Importin alpha-S2) (Karyopherin subunit alpha-6)Kpna6 Kpna5O353454
Inner centromere proteinIncenpQ9WU624
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 (EC 2.7.4.21) (EC 2.7.4.24) (Diphosphoinositol pentakisphosphate kinase 2) (Histidine acid phosphatase domain-containing protein 1) (InsP6 and PP-IP5 kinase 2) (VIP1 homolog 2) (mmVIP2)Ppip5k2 Hisppd1 Kiaa0433 Vip2Q6ZQB64
Inositol monophosphatase 1 (IMP 1) (IMPase 1) (EC 3.1.3.25) (D-galactose 1-phosphate phosphatase) (EC 3.1.3.94) (Inositol-1(or 4)-monophosphatase 1) (Lithium-sensitive myo-inositol monophosphatase A1)Impa1O550234
Inositol polyphosphate-5-phosphatase A (Putative uncharacterized protein)Inpp5aQ3TZT44
Insulin-like growth factor-binding protein complex acid labile subunit (ALS)Igfals Albs AlsP703894
Integrator complex subunit 7 (Int7)Ints7Q7TQK14
Integrin alpha M, isoform CRA_a (Integrin alpha-M)Itgam mCG_133489E9Q6044
Integrin beta-1-binding protein 1 (Bodenin)Itgb1bp1O356714
Interferon-activable protein 202 (Ifi-202) (Interferon-inducible protein p202) (Lupus susceptibility protein p202)Ifi202 Ifi202a Ifi202bQ9R0024
Interleukin 10 receptor 2 (Interleukin 10 receptor, beta) (Interleukin 10 receptor, beta, isoform CRA_a) (Interleukin-10 receptor subunit beta) (Putative uncharacterized protein)Il10rb Il10r2 mCG_11439Q8VHM74
Interleukin-17 receptor A (IL-17 receptor A) (IL-17RA) (CD antigen CD217)Il17ra Il17rQ609434
Intermediate conductance calcium-activated potassium channel protein 4 (SK4) (SKCa 4) (SKCa4) (IK1) (KCa3.1) (KCa4)Kcnn4O891094
Intersectin-2Itsn2E9QNG14
Isoamyl acetate-hydrolyzing esterase 1 homolog (EC 3.1.-.-)Iah1Q9DB294
Isopentenyl-diphosphate Delta-isomerase 1 (Isopentenyl-diphosphate delta isomerase)Idi1 mCG_4413G3XA484
Josephin-2Josd2D3YTZ74
Keratin, type I cuticular Ha1 (HKA-1) (Hair keratin, type I Ha1) (Keratin-31) (K31)Krt31 Hka1 Krt1-1 Krtha1Q617654
Keratin, type II cuticular Hb5 (Keratin-85) (K85) (Type II hair keratin Hb5) (Type-II keratin Kb25)Krt85 Krt2-18 Krthb5Q9Z2T64
KIF1-binding proteinKif1bp Kbp Kiaa1279Q6ZPU94
KinectinKtn1Q615954
KinectinKtn1F8VQC74
Kinesin family member 13BKif13bE9Q4K74
Kinesin family member 1B, isoform CRA_a (Kinesin-like protein KIF1B)Kif1b mCG_141691A2AH754
Kinesin-like proteinKif3aQ3TET14
Kinesin-like protein KIF14Kif14E9Q3T34
Kinesin-like protein KIF21BKif21bF8VQE24
Kinesin-like protein KIFC1Kifc1 Kifc4 Kifc5a Kifc5bQ9QWT94
Kinetochore protein NDC80 homolog (Kinetochore protein Hec1) (Kinetochore-associated protein 2)Ndc80 Hec1 Kntc2Q9D0F14
KN motif and ankyrin repeat domain-containing protein 2 (Ankyrin repeat domain-containing protein 25)Kank2 Ankrd25Q8BX024
KN motif and ankyrin repeat domain-containing protein 4 (Ankyrin repeat domain-containing protein 38)Kank4 Ankrd38Q6P9J54
L-fucose kinase (Fucokinase) (EC 2.7.1.52)FukQ7TMC84
L-lactate dehydrogenase (EC 1.1.1.27)Ldha Ldh1 mCG_19938Q564E24
La-related protein 1Larp1Z4YJT34
La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5)Larp4b D13Wsu64e Kiaa0217 Larp5Q6A0A24
La-related protein 7 (La ribonucleoprotein domain family member 7)Larp7 D3Wsu161eQ05CL84
Lamin-B receptor (Integral nuclear envelope inner membrane protein)LbrQ3U9G94
Lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma (Thymopoietin isoforms beta/delta/epsilon/gamma) (TP beta/delta/epsilon/gamma)Tmpo Lap2Q610294
Laminin subunit alpha-1 (Laminin A chain) (Laminin-1 subunit alpha) (Laminin-3 subunit alpha) (S-laminin subunit alpha) (S-LAM alpha)Lama1 Lama Lama-1P191374
Laminin subunit alpha-2 (Laminin M chain) (Laminin-12 subunit alpha) (Laminin-2 subunit alpha) (Laminin-4 subunit alpha) (Merosin heavy chain)Lama2Q606754
LanC-like protein 1 (40 kDa erythrocyte membrane protein) (p40)Lancl1 Gpr69aO891124
LanC-like protein 2 (Fragment)Lancl2F6RJV64
Large neutral amino acids transporter small subunit 4 (L-type amino acid transporter 4) (Solute carrier family 43 member 2)Slc43a2 Lat4Q8CGA34
Large subunit GTPase 1 homolog (EC 3.6.1.-)Lsg1 D16Bwg1547eQ3UM184
LETM1 and EF-hand domain-containing protein 1, mitochondrial (Leucine zipper-EF-hand-containing transmembrane protein 1)Letm1Q9Z2I04
Leucine-rich repeat and calponin homology domain-containing protein 3 (Lrch3 protein)Lrch3B2RXP14
Leucine-rich repeat and calponin homology domain-containing protein 4Lrch4Q921G64
Leucine-rich repeat-containing protein 40Lrrc40Q9CRC84
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