EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Leucine-rich repeat-containing protein 7 (Densin-180) (Densin) (Protein LAP1)Lrrc7 Kiaa1365 Lap1Q80TE74
Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1)Lrig1P701934
Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (D-factor/LIF receptor) (CD antigen CD118)LifrP427034
Leukosialin (B-cell differentiation antigen LP-3) (Leukocyte sialoglycoprotein) (Lymphocyte antigen 48) (Ly-48) (Sialophorin) (CD antigen CD43)SpnP157024
LIM and senescent cell antigen-like-containing domain proteinLims1E9QP624
Liprin-beta-2 (Protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2, isoform CRA_a)Ppfibp2 mCG_141440G3X9574
Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (LACS 3)Acsl3 Acs3 Facl3Q9CZW44
Lymphocyte antigen 75Ly75A2AW864
Lysine-specific histone demethylase 1A (EC 1.-.-.-) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2)Kdm1a Aof2 Kiaa0601 Lsd1Q6ZQ884
Lysophospholipid acyltransferase 5 (LPLAT 5) (EC 2.3.1.-) (1-acylglycerophosphocholine O-acyltransferase) (EC 2.3.1.23) (1-acylglycerophosphoethanolamine O-acyltransferase) (EC 2.3.1.n7) (1-acylglycerophosphoserine O-acyltransferase) (EC 2.3.1.n6) (Lysophosphatidylcholine acyltransferase) (LPCAT) (Lyso-PC acyltransferase) (Lysophosphatidylcholine acyltransferase 3) (Lyso-PC acyltransferase 3) (mLPCAT3) (Lysophosphatidylethanolamine acyltransferase) (LPEAT) (Lyso-PE acyltransferase) (Lysophosphatidylserine acyltransferase) (LPSAT) (Lyso-PS acyltransferase) (Membrane-bound O-acyltransferase domain-containing protein 5) (O-acyltransferase domain-containing protein 5)Lpcat3 Grcc3f Mboat5 Oact5Q91V014
Macrophage colony-stimulating factor 1 (CSF-1) (MCSF) [Cleaved into: Processed macrophage colony-stimulating factor 1]Csf1 CsfmP071414
Macrophage metalloelastase (MME) (EC 3.4.24.65) (Matrix metalloproteinase-12) (MMP-12)Mmp12 Mme MmelP349604
Maestro heat-like repeat family member 6Mroh6V9GX814
MAGUK p55 subfamily member 5 (Protein associated with Lin-7 1)Mpp5 Pals1Q9JLB24
Malignant T-cell-amplified sequence 1 (MCT-1) (Multiple copies T-cell malignancies 1)Mcts1Q9DB274
Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain]Masp2Q91WP04
MCG1050941 (Type II keratin Kb14)Gm5414 EG406223 mCG_1050941Q6IFZ84
MCG125477, isoform CRA_a (RAS protein activator-like-3)Rasal3 mCG_125477D3Z6Z74
MCG13402, isoform CRA_c (Polypyrimidine tract binding protein 1) (Polypyrimidine tract-binding protein 1) (Putative uncharacterized protein)Ptbp1 mCG_13402Q922I74
MCG134445, isoform CRA_a (Maestro heat-like repeat family member 1)Mroh1 Heatr7a mCG_134445G3XA214
MCG16669, isoform CRA_a (TAR DNA binding protein) (TAR DNA-binding protein 43) (TARDBP S6)Tardbp TARDBP mCG_16669Q8R0B44
MCG21719 (Ragulator complex protein LAMTOR5)Lamtor5 Hbxip mCG_21719G3UW704
MCG489271700071K01Rik mCG_48927Q3V2K04
MCG49559 (Putative uncharacterized protein) (Syntaxin-11)Stx11 mCG_49559Q3U5V84
Mediator of RNA polymerase II transcription subunit 14 (Cofactor required for Sp1 transcriptional activation subunit 2) (CRSP complex subunit 2) (Mediator complex subunit 14) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170)Med14 Crsp2 Gm641 Trap170A2ABV54
Melanoregulin (Dilute suppressor protein) (Whn-dependent transcript 2)Mreg Dsu Gm974 Wdt2Q6NVG54
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)Mbd3Q9Z2D84
MHC class I antigenH2-Tw5Q4KN894
MHC class I antigen (MHC class I antigen splice variant Bl.1) (Major histocompatibility complex class I b)H2-BlO194404
MHC classIb T5 (Predicted gene 8909)Gm8909 EG667977 H2-T5A7VMS64
MICOS complex subunit Mic26 (Apolipoprotein O) (MICOS complex subunit Mic23) (Protein FAM121B)Apoo Fam121b Mic23 Mic26Q9DCZ44
Microtubule-actin cross-linking factor 1 (Fragment)Macf1F7ACR94
Microtubule-associated protein RP/EB family member 2 (Fragment)Mapre2D3YYK84
Milk fat globule-EGF factor 8 protein, isoform CRA_a (Putative uncharacterized protein)Mfge8 mCG_6301Q3TDU54
Mini-chromosome maintenance complex-binding protein (MCM-BP) (MCM-binding protein)McmbpQ8R3C04
Misshapen-like kinase 1 (Misshapen-like kinase 1 (Zebrafish), isoform CRA_d)Mink1 mCG_134369G3X9G24
Mitochondrial glutamate carrier 2 (GC-2) (Glutamate/H(+) symporter 2) (Solute carrier family 25 member 18)Slc25a18 Gc2Q9DB414
Mitochondrial import inner membrane translocase subunit TIM44Timm44 Mimt44 Tim44O358574
Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR)MsraQ9D6Y74
Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)Map3k4 Mekk4O086484
Mitogen-activated protein kinase kinase kinase kinase (EC 2.7.11.1)Map4k5E9PX304
Mitogen-activated protein kinase kinase kinase kinase 4Map4k4F8VPL54
Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient 1-like protein 1) (MAD1-like protein 1)Mad1l1 Mad1Q9WTX84
Monoacylglycerol lipase ABHD12 (EC 3.1.1.23) (2-arachidonoylglycerol hydrolase) (Abhydrolase domain-containing protein 12)Abhd12Q99LR14
Mothers against decapentaplegic homolog (MAD homolog) (Mothers against DPP homolog) (SMAD family member)Smad2E9Q3M04
Mothers against decapentaplegic homolog 2 (MAD homolog 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2) (SMAD family member 2) (SMAD 2) (Smad2)Smad2 Madh2 Madr2Q624324
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (mMad3) (SMAD family member 3) (SMAD 3) (Smad3)Smad3 Madh3Q8BUN54
Mothers against decapentaplegic homolog 5 (MAD homolog 5) (Mothers against DPP homolog 5) (Dwarfin-C) (Dwf-C) (SMAD family member 5) (SMAD 5) (Smad5) (mSmad5)Smad5 Madh5 Msmad5P974544
Multidrug resistance protein 1A (EC 3.6.3.44) (ATP-binding cassette sub-family B member 1A) (MDR1A) (Multidrug resistance protein 3) (P-glycoprotein 3)Abcb1a Abcb4 Mdr1a Mdr3 Pgy-3 Pgy3P214474
Myeloid leukemia factor 2 (Myelodysplasia-myeloid leukemia factor 2)Mlf2Q99KX14
Myeloid-derived growth factor (MYDGF) (Interleukin-25) (IL-25) (Stromal cell-derived growth factor SF20)Mydgf D17Wsu104e Il25Q9CPT44
Myosin-1 (Myosin heavy chain 1) (Myosin heavy chain 2x) (MyHC-2x) (Myosin heavy chain, skeletal muscle, adult 1)Myh1Q5SX404
Myosin-10 (Putative uncharacterized protein)Myh10Q3UH594
Myosin-11Myh11E9QPE74
Myosin-11 (Myosin heavy chain 11) (Myosin heavy chain, smooth muscle isoform) (SMMHC)Myh11O086384
Myotubularin-related protein 5 (SET-binding factor 1) (Sbf1)Sbf1 Kiaa3020 Mtmr5Q6ZPE24
Myotubularin-related protein 6 (EC 3.1.3.-)Mtmr6Q8VE114
N-acetylgalactosamine kinase (Putative uncharacterized protein)Galk2Q8BUU74
N-acylglucosamine 2-epimerase (AGE) (EC 5.1.3.8) (GlcNAc 2-epimerase) (N-acetyl-D-glucosamine 2-epimerase) (Renin-binding protein) (RnBP)RenbpP823434
N-alpha-acetyltransferase 10 (EC 2.3.1.255) (N-terminal acetyltransferase complex ARD1 subunit homolog A) (NatA catalytic subunit Naa10)Naa10 Ard1 Ard1a Te2Q9QY364
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (Octs2) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)Slc9a3r2 Nherf2Q9JHL14
NAD kinase (EC 2.7.1.23) (Poly(P)/ATP NAD kinase)NadkP580584
NAD(P) transhydrogenase, mitochondrial (EC 1.6.1.2) (Nicotinamide nucleotide transhydrogenase) (Pyridine nucleotide transhydrogenase)NntQ619414
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Complex I-ASHI) (CI-ASHI) (NADH-ubiquinone oxidoreductase ASHI subunit)Ndufb8Q9D6J54
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (EC 1.6.5.3) (EC 1.6.99.3) (Complex I-20kD) (CI-20kD) (NADH-ubiquinone oxidoreductase 20 kDa subunit)Ndufs7Q9DC704
Nck-associated protein 1-like (Hematopoietic protein 1)Nckap1l Hem1Q8K1X44
Nck-associated protein 5-like (Centrosomal protein of 169 kDa) (Cep169)Nckap5l Cep169Q6GQX24
NEDD4 family-interacting protein 2 (NEDD4 WW domain-binding protein 5A) (Fragment)Ndfip2 Kiaa1165 N4wbp5AQ91ZP64
Negative elongation factor B (NELF-B) (Cofactor of BRCA1)Nelfb Cobra1 MNCb-5210Q8C4Y34
Neural cell adhesion molecule 1Ncam1E9QB014
Neural cell adhesion molecule L1L1camA2AFG74
Neurobeachin-like protein 2Nbeal2 Kiaa0540Q6ZQA04
Neurocalcin-delta (Fragment)NcaldD3YVA24
Neurofibromin (Fragment)Nf1Q5SYH94
Neurofilament heavy polypeptide (NF-H) (200 kDa neurofilament protein) (Neurofilament triplet H protein)Nefh Kiaa0845 NfhP192464
Neurogenic locus notch homolog protein 1 (Notch 1) (Motch A) (mT14) (p300) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]Notch1 MotchQ017054
Neurolysin, mitochondrial (EC 3.4.24.16) (Microsomal endopeptidase) (MEP) (Mitochondrial oligopeptidase M) (Neurotensin endopeptidase)NlnQ91YP24
Neurotrypsin (EC 3.4.21.-) (Brain-specific serine protease 3) (BSSP-3) (Motopsin) (Serine protease 12)Prss12 Bssp3O087624
NFX1-type zinc finger-containing protein 1Znfx1Q8R1514
Nicalin (Nicastrin-like protein)NclnQ8VCM84
Nitric oxide synthase-interacting protein (E3 ubiquitin-protein ligase NOSIP) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase NOSIP)NosipQ9D6T04
Nuclear autoantigenic sperm protein (Nuclear autoantigenic sperm protein (Histone-binding), isoform CRA_c)Nasp mCG_19661B1AU754
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]Nfkb1P257994
Nuclear fragile X mental retardation-interacting protein 2 (82 kDa FMRP-interacting protein) (82-FIP) (FMRP-interacting protein 2)Nufip2 Kiaa1321Q5F2E74
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214)Nup214 Kiaa0023Q80U934
Nuclear pore complex protein Nup88 (88 kDa nucleoporin) (Nucleoporin Nup88)Nup88Q8CEC04
Nuclear pore complex protein Nup98-Nup96 [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]Nup98Q6PFD94
Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140)Nolc1 Kiaa0035E9Q5C94
Nucleolar complex protein 4 homolog (NOC4 protein homolog) (NOC4-like protein) (Nucleolar complex-associated protein 4-like protein)Noc4lQ8BHY24
Nucleolar pre-ribosomal-associated protein 1 (URB1 ribosome biogenesis 1 homolog)Urb1 Kiaa0539 Npa1Q571H04
Nucleolar protein 6 (Nucleolar RNA-associated protein) (Nrap)Nol6Q8R5K44
Nucleolar protein 9 (Pumilio domain-containing protein NOP9)Nop9Q8BMC44
Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1)Ubtf Tcfubf Ubf-1 Ubf1P259764
Nucleoporin NUP188 homologNup188 Kiaa0169Q6ZQH84
Nucleoporin SEH1 (Nup107-160 subcomplex subunit SEH1)Seh1lQ8R2U04
Nucleoredoxin (EC 1.8.1.8) (Protein Red-1)Nxn Gn25P973464
Olfactomedin-like protein 3Olfml3Q8BK624
Oncostatin-M-specific receptor subunit beta (Interleukin-31 receptor subunit beta) (IL-31 receptor subunit beta) (IL-31R subunit beta) (IL-31R-beta) (IL-31RB)Osmr OsmrbO704584
OTU domain-containing protein 7B (EC 3.4.19.12) (Cellular zinc finger anti-NF-kappa-B protein) (Zinc finger A20 domain-containing protein 1) (Zinc finger protein Cezanne)Otud7bB2RUR84
OX-2 membrane glycoprotein (MRC OX-2 antigen) (CD antigen CD200)Cd200 Mox2O549014
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