EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
P2X purinoceptor 4P2rx4D3YYR54
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)Sin3a Kiaa4126Q605204
PapilinPaplnQ9EPX24
Pard3 protein (Partitioning defective 3 homolog)Pard3B7ZNY34
PC4 and SFRS1-interacting protein (Lens epithelium-derived growth factor) (mLEDGF)Psip1 LedgfQ99JF84
PDZ domain-containing protein GIPC2 (SemaF cytoplasmic domain-associated protein 2) (SEMCAP-2)Gipc2 Semcap2Q9Z2H74
Pecanex-like protein 3 (Pecanex homolog protein 3)Pcnx3 Pcnxl3Q8VI594
Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (13 kDa FK506-binding protein) (13 kDa FKBP) (FKBP-13) (FK506-binding protein 2) (FKBP-2) (Immunophilin FKBP13) (Rotamase)Fkbp2 Fkbp13P458784
Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (FK506-binding protein 5) (FKBP-5) (Rotamase)Fkbp5 Fkbp51Q643784
Peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) (EC 2.3.2.27) (EC 5.2.1.8) (CYC4) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (RING-type E3 ubiquitin transferase isomerase-like 2) (Rotamase PPIL2)Ppil2Q9D7874
Periodic tryptophan protein 1 homologPwp1Q99LL54
Periodic tryptophan protein 2 homologPwp2 Pwp2hQ8BU034
Peripherin (Peripherin 1, isoform CRA_b)Prph Prph1 mCG_18385G3X9814
Peroxiredoxin-5, mitochondrialPrdx5H3BJQ74
Peroxisomal acyl-coenzyme A oxidase 1 (AOX) (EC 1.3.3.6) (Palmitoyl-CoA oxidase)Acox1 Acox PaoxQ9R0H04
Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14)Pex14Q9R0A04
PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein)PcnpQ6P8I44
Phenylalanine--tRNA ligase alpha subunitFarsaE9PWY94
Phosphatidylinositol 4-kinase alphaPi4kaA0A140T8I94
Phosphatidylinositol 4-phosphate 5-kinase type-1 alphaPip5k1aF8WI184
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1-gamma) (PtdIns(4)P-5-kinase 1 gamma) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I gamma) (PIP5KIgamma)Pip5k1c Kiaa0589O701614
Phosphatidylinositol-glycan-specific phospholipase D (PI-G PLD) (EC 3.1.4.50) (Glycoprotein phospholipase D) (Glycosyl-phosphatidylinositol-specific phospholipase D) (GPI-PLD) (GPI-specific phospholipase D)Gpld1O703624
Phospholipase D1 (Phospholipase D1, isoform CRA_b)Pld1 mCG_20179Q6NVF24
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp11aE9Q3G74
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp11cE9QKK84
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp9aQ8C4G34
Phospholipid-transporting ATPase 11C (EC 3.6.3.1) (ATPase class VI type 11C) (P4-ATPase flippase complex alpha subunit ATP11C)Atp11cQ9QZW04
Phospholipid-transporting ATPase IA (EC 3.6.3.1) (ATPase class I type 8A member 1) (Chromaffin granule ATPase II) (P4-ATPase flippase complex alpha subunit ATP8A1)Atp8a1 Atpc1P707044
Phosphoribosyl pyrophosphate synthase-associated protein 1 (PRPP synthase-associated protein 1) (39 kDa phosphoribosypyrophosphate synthase-associated protein) (PAP39)Prpsap1Q9D0M14
Phostensin (Protein phosphatase 1 F-actin cytoskeleton-targeting subunit) (Protein phosphatase 1 regulatory subunit 18)Ppp1r18Q8BQ304
Piezo-type mechanosensitive ion channel componentPiezo1 Fam38aE9PUQ94
PIH1 domain-containing protein 1 (Nucleolar protein 17 homolog)Pih1d1 Nop17Q9CQJ24
Placenta-specific gene 8 protein (Onzin) (Protein C15)Plac8Q9JI484
Plasma alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucoside fucohydrolase 2) (Alpha-L-fucosidase 2)Fuca2Q99KR84
Platelet-activating factor acetylhydrolase IB subunit gamma (EC 3.1.1.47) (PAF acetylhydrolase 29 kDa subunit) (PAF-AH 29 kDa subunit) (PAF-AH subunit gamma) (PAFAH subunit gamma)Pafah1b3 PafahgQ612054
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (Platelet-derived growth factor alpha receptor) (CD antigen CD140a)PdgfraP266184
Pleckstrin homology domain-containing family H member 3 (PH domain-containing family H member 3)Plekhh3Q8VCE94
Pleckstrin homology-like domain family B member 1Phldb1E9PWB14
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)Phldb2 Ll5bQ8K1N24
Pleiotropic regulator 1Plrg1Q922V44
PML-RARA-regulated adapter molecule 1 (PRAM-1)Pram1Q6BCL14
Poly [ADP-ribose] polymerase 9 (PARP-9) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 9) (ARTD9) (B aggressive lymphoma protein homolog)Parp9 BalQ8CAS94
Poly(rC)-binding protein 4 (Alpha-CP4)Pcbp4P577244
Polyadenylate-binding protein (PABP)Pabpc6 Pabpc3Q9D4E64
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)Pabpn1 Pab2 Pabp2Q8CCS64
Polypeptide N-acetylgalactosaminyltransferase 1 (EC 2.4.1.41) (Polypeptide GalNAc transferase 1) (GalNAc-T1) (pp-GaNTase 1) (Protein-UDP acetylgalactosaminyltransferase 1) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1) [Cleaved into: Polypeptide N-acetylgalactosaminyltransferase 1 soluble form]Galnt1O089124
Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)Fig4 Kiaa0274 Sac3Q91WF74
Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)Pnpt1 PnpaseQ8K1R34
Potassium channel tetramerisation domain containing 12b (Potassium channel tetramerisation domain containing 12b, isoform CRA_a) (Potassium channel tetramerisation domain-containing 12b) (Putative uncharacterized protein)Kctd12b mCG_61677Q8C7J64
Ppfia1 protein (Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF),-interacting protein (liprin), alpha 1)Ppfia1B2RXW84
PRA1 family protein 2Praf2 DXImx39eQ9JIG84
pre-mRNA 3' end processing protein WDR33 (WD repeat-containing protein 33) (WD repeat-containing protein WDC146)Wdr33 Wdc146Q8K4P04
Pre-mRNA 3'-end-processing factor FIP1 (FIP1-like 1 protein)Fip1l1Q9D8244
Pre-mRNA-splicing factor 38APrpf38aQ4FK664
Pre-mRNA-splicing factor 38BPrpf38bQ80SY54
Pre-mRNA-splicing factor SPF27 (Breast carcinoma-amplified sequence 2 homolog) (DNA amplified in mammary carcinoma 1 protein)Bcas2 Dam1Q9D2874
pre-rRNA processing protein FTSJ3 (EC 2.1.1.-) (2'-O-ribose RNA methyltransferase SPB1 homolog) (Protein ftsJ homolog 3) (Putative rRNA methyltransferase 3)Ftsj3Q9DBE94
Predicted gene 5093Gm5093E9PZB34
Prickle-like protein 1Prickle1Q3U5C74
Probable 28S rRNA (cytosine-C(5))-methyltransferase (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 5) (Williams-Beuren syndrome chromosomal region 20A protein homolog)Nsun5 Wbscr20 Wbscr20aQ8K4F64
Probable ATP-dependent RNA helicase DDX49 (EC 3.6.4.13) (DEAD box protein 49)Ddx49Q4FZF34
Probable ATP-dependent RNA helicase YTHDC2 (EC 3.6.4.13)Ythdc2B2RR834
Probable RNA-binding protein 19 (RNA-binding motif protein 19)Rbm19Q8R3C64
Proline/serine-rich coiled-coil protein 1Psrc1 Dda3Q9D0P74
Prosaposin receptor GPR37 (G-protein coupled receptor 37)Gpr37Q9QY424
Prostaglandin reductase 1 (PRG-1) (EC 1.3.1.-) (15-oxoprostaglandin 13-reductase) (EC 1.3.1.48) (NADP-dependent leukotriene B4 12-hydroxydehydrogenase) (EC 1.3.1.74)Ptgr1 Ltb4dhQ91YR94
Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Rpn13 homolog)Adrm1 Gp110Q9JKV14
Proteasome assembly chaperone 2 (CD40 ligand-activated specific transcript 3) (Tumor necrosis factor superfamily member 5-induced protein 1)Psmg2 Clast3 Tnfsf5ip1Q9EST44
Proteasome assembly chaperone 3 (PAC-3) (mPAC3)Psmg3 Pac3Q9CZH34
Proteasome subunit alpha-type 7-like (EC 3.4.25.1)Psma8 Psma7lQ9CWH64
Protein 4.1Epb41 Epb4.1A2A8394
Protein bicaudal D homolog 1 (Bic-D 1)Bicd1Q8BR074
Protein CMSS1 (Cms1 ribosomal small subunit homolog)Cmss1Q9CZT64
Protein DDI1 homolog 2Ddi2A2ADY94
Protein disulfide-isomerase TMX3 (EC 5.3.4.1) (Thioredoxin domain-containing protein 10) (Thioredoxin-related transmembrane protein 3)Tmx3 Kiaa1830 Txndc10Q8BXZ14
Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1)Enah Mena Ndpp1Q031734
Protein FAM45AFam45aQ9D8N24
Protein FRG1 (FSHD region gene 1 protein)Frg1P973764
Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4)Mdm4 MdmxO356184
Protein NDRG3 (N-myc downstream-regulated gene 3 protein) (Protein Ndr3)Ndrg3 Ndr3Q9QYF94
Protein NipSnap homolog 2 (NipSnap2) (Glioblastoma-amplified sequence)Gbas Nipsnap2O551264
Protein O-GlcNAcase (OGA) (EC 3.2.1.169) (Beta-N-acetylhexosaminidase) (Beta-hexosaminidase) (Bifunctional protein NCOAT) (Meningioma-expressed antigen 5) (N-acetyl-beta-D-glucosaminidase) (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase)Mgea5 Hexc Kiaa0679Q9EQQ94
Protein pelota homolog (EC 3.1.-.-)PeloQ80X734
Protein phosphatase 1 regulatory subunit 12C (Protein phosphatase 1 myosin-binding subunit of 85 kDa) (Protein phosphatase 1 myosin-binding subunit p85)Ppp1r12c Mbs85Q3UMT14
Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta)Ppm1b Pp2c2 Pppm1bP369934
Protein phosphatase 2, regulatory subunit B (B56), delta isoform, isoform CRA_a (Protein phosphatase 2A B56 delta subunit)Ppp2r5d mCG_2696Q7TNL54
Protein PRRC2APrrc2aG3UX484
Protein PRRC2CPrrc2cS4R2944
Protein PRRC2C (BAT2 domain-containing protein 1) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)Prrc2c Bat2d Bat2d1 Bat2l2 Kiaa1096Q3TLH44
Protein quaking (MqkI) (qkI)Qki Qk Qk1 Qka1Q9QYS94
Protein regulator of cytokinesis 1Prc1Q99K434
Protein regulator of cytokinesis 1 (Protein regulator of cytokinesis 1, isoform CRA_b)Prc1 mCG_19465G3UY194
Protein RRP5 homolog (Apoptosis-linked gene 4 protein) (Programmed cell death protein 11)Pdcd11 Alg4 Kiaa0185Q6NS464
Protein SDA1 homolog (SDA1 domain-containing protein 1)Sdad1Q80UZ24
Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L)Sel1l Sel1hQ9Z2G64
Protein sprouty homolog 2 (Spry-2)Spry2Q9QXV84
Protein TANC1Tanc1E9QAF94
Protein transport protein Sec24A (SEC24-related protein A)Sec24aQ3U2P14
Protein unc-93 homolog B1 (Unc-93B1)Unc93b1 Unc93bQ8VCW44
Protein Z-dependent protease inhibitor (PZ-dependent protease inhibitor) (PZI) (Serpin A10)Serpina10 ZpiQ8R1214
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