EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein-glutamine gamma-glutamyltransferase E (EC 2.3.2.13) (Transglutaminase E) (TG(E)) (TGE) (TGase E) (Transglutaminase-3) (TGase-3) [Cleaved into: Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain]Tgm3 Tgase3Q081894
Protocadherin 7 (Protocadherin 7, isoform CRA_c)Pcdh7 mCG_9825E9Q2S04
Putative uncharacterized protein (Regulatory-associated protein of mTOR)Rptor 4932417H02Rik mCG_15044A2ACM04
Putative uncharacterized protein (Signal transducing adapter molecule 1)StamQ3UGN94
Putative uncharacterized protein (Sorting nexin 1) (Sorting nexin-1)Snx1Q6NZD24
Putative uncharacterized protein (Sorting nexin 12, isoform CRA_c) (Sorting nexin-12)Snx12 mCG_2194Q6ZWQ54
Putative uncharacterized protein (Sorting nexin-12)Snx12Q3V2H34
Putative uncharacterized protein (Splicing factor 3b, subunit 2)Sf3b2 mCG_19856Q3UJB04
Putative uncharacterized protein (Testin) (Testis derived transcript, isoform CRA_b)Tes mCG_11251Q3ULB14
Putative uncharacterized protein (Tissue factor pathway inhibitor)TfpiQ8BSB74
Putative uncharacterized protein (Transferrin receptor protein 1) (Transferrin receptor, isoform CRA_c)Tfrc mCG_129940Q8C8724
Putative uncharacterized protein (Tumor protein D52-like 2, isoform CRA_c) (Tumor protein D54)Tpd52l2 mCG_23059Q3TAI44
Putative uncharacterized protein (Voltage-gated potassium channel subunit beta-2)Kcnab2Q3UPV64
Putative uncharacterized protein (X-prolyl aminopeptidase (Aminopeptidase P) 1, soluble, isoform CRA_b) (Xaa-Pro aminopeptidase 1)Xpnpep1 mCG_20868Q3UE924
Pyruvate kinase (EC 2.7.1.40)Pklr mCG_17567G3X9254
Rab3 GTPase-activating protein non-catalytic subunit (Rab3 GTPase-activating protein 150 kDa subunit) (Rab3-GAP p150) (Rab3-GAP150) (Rab3-GAP regulatory subunit)Rab3gap2 Kiaa0839Q8BMG74
Rab5 GDP/GTP exchange factor (Rabex-5)Rabgef1 Rabex5Q9JM134
RAB9, member RAS oncogene family (Fragment)Rab9A2AFP54
Ragulator complex protein LAMTOR3 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3) (MEK-binding partner 1) (Mp1) (Mitogen-activated protein kinase kinase 1-interacting protein 1) (Mitogen-activated protein kinase scaffold protein 1)Lamtor3 Map2k1ip1 Mapbp Mapksp1O886534
RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1)Reps1O549164
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (mAVO3) (Protein pianissimo)Rictor Kiaa1999Q6QI064
RAS protein activator like-3Rasal3Q8C2K54
Ras suppressor protein 1 (Ras suppressor protein 1, isoform CRA_a)Rsu1 mCG_15700A2AUR74
Ras-related protein Rab-15Rab15Q8K3864
Ras-related protein Rab-15Rab15Q3TYH24
Ras-related protein Rab-27BRab27bQ99P584
Receptor expression-enhancing protein 5 (GP106) (Polyposis locus protein 1 homolog) (Protein TB2 homolog)Reep5 Dp1Q608704
Receptor protein serine/threonine kinase (EC 2.7.11.30)Tgfbr1Q9D5H84
Receptor tyrosine-protein kinase erbB-2 (EC 2.7.10.1) (Proto-oncogene Neu) (Proto-oncogene c-ErbB-2) (p185erbB2) (CD antigen CD340)Erbb2 Kiaa3023 NeuP704244
Receptor tyrosine-protein kinase erbB-3 (EC 2.7.10.1) (Glial growth factor receptor) (Proto-oncogene-like protein c-ErbB-3)Erbb3Q615264
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1) (Serine/threonine-protein kinase RIP)Ripk1 Rinp RipQ608554
Receptor-type tyrosine-protein phosphatase delta (Protein-tyrosine phosphatase delta) (R-PTP-delta) (EC 3.1.3.48)PtprdQ644874
Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)Ptprm Kiaa4044P288284
Regulator of G-protein signaling 19 (RGS19)Rgs19Q9CX844
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)Rptor RaptorQ8K4Q04
REST corepressor 1 (Protein CoREST)Rcor1 D12Wsu95e Kiaa0071Q8CFE34
ReticulonRtn4Q8BH784
Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1)Gprc5a Rai3 Raig1Q8BHL44
Rho GTPase-activating protein 18 (Rho-type GTPase-activating protein 18)Arhgap18Q8K0Q54
Rho guanine nucleotide exchange factor 1Arhgef1E9PUF74
Rho guanine nucleotide exchange factor 40 (Protein SOLO)Arhgef40 SoloQ3UPH74
Rho guanine nucleotide exchange factor 7 (Fragment)Arhgef7D3Z0V24
Rho-associated protein kinase (EC 2.7.11.1)Rock2F8VPK54
Rho-related BTB domain-containing protein 3 (EC 3.6.1.-)Rhobtb3 Kiaa0878Q9CTN44
Rho-related GTP-binding protein RhoJ (Tc10-like GTP-binding protein)Rhoj Arhj Rhoi Rhot Tc10l TclQ9ER714
Rho-related GTP-binding protein RhoU (Rho GTPase-like protein ARHU) (Wnt-1 responsive Cdc42 homolog 1) (WRCH-1)Rhou Arhu G28k Wrch1Q9EQT34
RhotekinRtknQ8C6B24
Ribonuclease T2-A (EC 3.1.27.-) (Ribonuclease 6-A)Rnaset2a Rnase6plC0HKG54
Ribonucleoprotein PTB-binding 1 (Protein raver-1)Raver1 Kiaa1978Q9CW464
Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase)Rpia RpiP479684
Ribosomal protein L19Rpl19A2A5474
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (S6K) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)Rps6kb1Q8BSK84
Ribosomal RNA small subunit methyltransferase NEP1 (EC 2.1.1.-) (18S rRNA (pseudouridine(1248)-N1)-methyltransferase) (18S rRNA Psi1248 methyltransferase) (Nucleolar protein EMG1 homolog) (Protein C2f) (Ribosome biogenesis protein NEP1)Emg1 C2f Grcc2fO351304
Ribosome biogenesis protein BOP1 (Block of proliferation 1 protein)Bop1 Kiaa0124P974524
RIKEN cDNA 4930544G11 (RIKEN cDNA 4930544G11 gene)4930544G11Rik mCG_125315Q9CR994
RNA 3'-terminal phosphate cyclase-like proteinRcl1 RnacQ9JJT04
RNA binding motif protein, X-linked-like-1 (Heterogeneous nuclear ribonucleoprotein G-like 1) (RNA binding motif protein, X chromosome retrogene) [Cleaved into: RNA binding motif protein, X-linked-like-1, N-terminally processed]Rbmxl1 RbmxrtQ91VM54
RNA polymerase II-associated protein 3Rpap3 D15Ertd682eQ9D7064
RNA-binding protein EWSEwsr1Q5SUT04
RNA-binding protein FUS (Fragment)FusG3UXT74
RUN and FYVE domain-containing protein 1 (Rab4-interacting protein)Rufy1 Rabip4Q8BIJ74
S1 RNA-binding domain-containing protein 1Srbd1Q497V54
SEC23-interacting protein (Sec23 interacting protein, isoform CRA_c)Sec23ip mCG_21024G3X9284
Sec24 related gene family, member B (S. cerevisiae) (Sec24-related gene family, member B (S. cerevisiae))Sec24bQ80ZX04
Secretory carrier-associated membrane protein (Secretory carrier membrane protein)Scamp3Q3UXS04
Secretory carrier-associated membrane protein 5 (Secretory carrier membrane protein 5)Scamp5Q9JKD34
Selenoprotein F (15 kDa selenoprotein)Selenof Sep15Q9ERR74
Selenoprotein P (SeP) (Plasma selenoprotein P)Selenop Selp Sepp1P702744
Sentrin-specific protease 3 (EC 3.4.22.68) (SUMO-1-specific protease 3) (Sentrin/SUMO-specific protease SENP3) (Smt3-specific isopeptidase 1) (Smt3ip1)Senp3 Smt3ip Smt3ip1Q9EP974
Septin-10Sept10Q8C6504
Septin-7Sept7E9Q9F54
Septin-9Sept9A2A6U34
Serine (or cysteine) peptidase inhibitor, clade B, member 6aSerpinb6aF8WIV24
Serine hydroxymethyltransferase, cytosolic (Fragment)Shmt1G3UZ264
Serine protease inhibitor A3F (Serpin A3F)Serpina3fQ80X764
Serine/arginine repetitive matrix protein 2Srrm2 Kiaa0324Q8BTI84
Serine/arginine-rich splicing factor 9 (Splicing factor, arginine/serine-rich 9)Srsf9 Sfrs9Q9D0B04
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf)Braf B-rafP280284
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase)Lats1 WartsQ8BYR24
Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9)Nek9 NerccQ8K1R74
Serine/threonine-protein kinase PAK 1 (p21 (CDKN1A)-activated kinase 1, isoform CRA_b)Pak1 mCG_7049G5E8844
Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)Acvrl1 Acvrlk1 Alk-1Q612884
Serine/threonine-protein kinase RIO1 (EC 2.7.11.1) (EC 3.6.3.-) (RIO kinase 1)Riok1Q922Q24
Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2)Riok2Q9CQS54
Serine/threonine-protein kinase SMG1 (SMG-1) (EC 2.7.11.1)Smg1 Kiaa0421Q8BKX64
Serine/threonine-protein kinase TAO2 (EC 2.7.11.1) (Thousand and one amino acid protein 2)Taok2 Kiaa0881Q6ZQ294
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PP2A subunit B isoform B55-delta) (PP2A subunit B isoform PR55-delta) (PP2A subunit B isoform R2-delta) (PP2A subunit B isoform delta)Ppp2r2d D7Ertd753e Kiaa1541Q925E74
Serine/threonine-protein phosphatase 4 regulatory subunit 1Ppp4r1Q8K2V14
Serum amyloid A-1 proteinSaa1P053664
Serum amyloid A-4 protein (Amyloid A-5 protein)Saa4 Saa5P315324
SH3 domain-binding protein 1Sh3bp1A2A5V44
Sideroflexin-3Sfxn3Q91V614
Signal peptidase complex catalytic subunit SEC11A (EC 3.4.21.89) (Endopeptidase SP18) (Microsomal signal peptidase 18 kDa subunit) (SPase 18 kDa subunit) (SEC11 homolog A) (SEC11-like protein 1) (SPC18) (Sid 2895)Sec11a Sec11l1 Sid2895 Spc18Q9R0P64
Signal peptide peptidase-like 2B (SPP-like 2B) (SPPL2b) (EC 3.4.23.-)Sppl2bQ3TD494
Signal recognition particle 54 kDa proteinSrp54b SRP54E9PXC04
Signal recognition particle 72Srp72E9Q7404
Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1)Sipa1l1 Kiaa0440Q8C0T54
Single-stranded DNA-binding proteinSsbp1 mCG_15097Q8R2K34
Slit homolog 2 protein (Slit-2) [Cleaved into: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product]Slit2Q9R1B94
SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho GTPase-activating protein 13)Srgap1 Arhgap13Q91Z694
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