EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Alkylglycerone-phosphate synthase (Alkyl-DHAP synthase) (EC 2.5.1.26)AgpsA2AL503
Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1)Ctnnal1 Catnal1O883273
Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66)InaP466603
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)Snca SynO550423
Amino acid transporterSlc1a5Q3UFR43
AMP deaminase (EC 3.5.4.6)Ampd2 mCG_4058A2AE273
Amylo-1,6-glucosidase, 4-alpha-glucanotransferaseAglF8VPN43
Amyloid beta A4 precursor protein-binding family A member 3 (Adapter protein X11gamma) (Neuron-specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3)Apba3 Mint3O888883
AN1-type zinc finger protein 2B (Fragment)Zfand2bE0CY183
AN1-type zinc finger protein 5 (Zinc finger A20 domain-containing protein 2) (Zinc finger protein 216)Zfand5 Za20d2 Zfp216 Znf216O888783
Anamorsin (Cytokine-induced apoptosis inhibitor 1) (Fe-S cluster assembly protein DRE2 homolog)Ciapin1Q8WTY43
Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen)Anapc7 Apc7Q9WVM33
Angio-associated migratory protein (Putative uncharacterized protein)Aamp mCG_114812Q3TJ223
Angiotensin-converting enzyme (ACE) (EC 3.2.1.-) (EC 3.4.15.1) (Dipeptidyl carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into: Angiotensin-converting enzyme, soluble form]Ace Dcp1P094703
Anion exchange proteinSlc4a2A0A0R4J1K43
Ankyrin repeat and SAM domain-containing protein 1A (Odin)Anks1a Anks1 Kiaa0229 OdinP596723
Ankyrin repeat domain-containing protein 46 (Ankyrin repeat small protein) (ANK-S)Ankrd46Q8BTZ53
Anterior gradient protein 2 homolog (AG-2) (mAG-2) (Protein Gob-4) (Secreted cement gland protein XAG-2 homolog)Agr2 Gob4O883123
AP-1 complex subunit gamma-1 (Adaptor protein complex AP-1, gamma 1 subunit) (Putative uncharacterized protein)Ap1g1Q8CBB73
AP-1 complex subunit mu-2 (AP-mu chain family member mu1B) (Adaptor protein complex AP-1 subunit mu-2) (Adaptor-related protein complex 1 subunit mu-2) (Clathrin assembly protein complex 1 mu-2 medium chain 2) (Golgi adaptor HA1/AP1 adaptin mu-2 subunit) (Mu-adaptin 2) (Mu1B-adaptin)Ap1m2Q9WVP13
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)Ap3s1Q9DCR23
Apolipoprotein L 7bApol7bB1AQP73
Arachidonate 15-lipoxygenase (15-LOX) (EC 1.13.11.33) (12/15-lipoxygenase) (12/15-LO) (Arachidonate 12-lipoxygenase, leukocyte-type) (12-LOX) (L-12LO) (EC 1.13.11.31) (Arachidonate omega-6 lipoxygenase)Alox15 Alox12lP396543
Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein homolog) (Nucleoporin-like protein RIP)Agfg1 Hrb RipQ8K2K63
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Centaurin-beta-1) (Cnt-b1)Acap1 Centb1 Kiaa0050Q8K2H43
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)Acap2 Centb2 Kiaa0041Q6ZQK53
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1Arap1E9PUB03
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)Asap1 Ddef1 Kiaa1249 Shag1Q9QWY83
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2Asap2D3YX853
ATP synthase subunit alphaAtp5a1 mCG_18273D3Z6F53
ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon)Atp5eP563823
ATP synthase subunit f, mitochondrialAtp5j2F8WHP83
ATP synthase subunit gammaAtp5c1Q8C2Q83
ATP-binding cassette sub-family A member 1 (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1)Abca1 Abc1P412333
ATP-binding cassette sub-family B member 7, mitochondrial (ATP-binding cassette transporter 7) (ABC transporter 7 protein)Abcb7 Abc7Q611023
ATP-binding cassette sub-family B member 9 (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (mABCB9) (TAP-like protein) (TAPL)Abcb9 Kiaa1520Q9JJ593
ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42)Ddx42Q810A73
ATP-dependent RNA helicase DDX55 (EC 3.6.4.13) (DEAD box protein 55)Ddx55 Kiaa1595Q6ZPL93
ATPase family AAA domain-containing protein 2 (EC 3.6.1.3)Atad2Q8CDM13
Attractin-like protein 1Atrnl1 Alp Atrnl Kiaa0534Q6A0513
Autophagy-related protein 9Atg9a Apg9l1 Atg9Q3ZAQ43
B-cell differentiation antigen CD72 (Lyb-2) (Lymphocyte antigen 32) (Ly-32) (CD antigen CD72)Cd72 Ly-32 Ly32 Lyb-2P218553
B-cell differentiation antigen CD72 (Putative uncharacterized protein)Cd72Q3UB583
B-cell receptor-associated protein 29 (BCR-associated protein 29) (Bap29)Bcap29 Bap29Q613343
Baculoviral IAP repeat-containing protein 6Birc6S4R1L53
BC035947 protein (CDNA sequence BC035947)BC035947B2RQY63
Bcl-2-associated transcription factor 1 (Btf)Bclaf1 Btf Kiaa0164Q8K0193
Beta-1,4-galactosyltransferase 1 (UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 1, isoform CRA_a)B4galt1 mCG_9808B1AXY53
Beta-1,4-glucuronyltransferase 1 (EC 2.4.1.-) (I-beta-1,3-N-acetylglucosaminyltransferase) (iGnT) (N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase) (Poly-N-acetyllactosamine extension enzyme) (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1)B4gat1 B3gnt1 B3gnt6Q8BWP83
Beta-secretase 2Bace2A0A0R4J0I83
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase (EC 1.5.1.15); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)]Mthfd2 NmdmcP181553
Bis(5'-adenosyl)-triphosphatase enpp4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4)Enpp4 Kiaa0879Q8BTJ43
Blood vessel epicardial substance (mBVES) (Popeye domain-containing protein 1) (Popeye protein 1)Bves Pop1 Popdc1Q9ES833
BolA-like protein 2Bola2Q8BGS23
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP)]Prg2 Mbp-1Q618783
BPI fold-containing family A member 1 (Palate lung and nasal epithelium clone protein)Bpifa1 Plunc Splunc1P973613
BPI fold-containing family B member 1 (Long palate, lung and nasal epithelium carcinoma-associated protein 1)Bpifb1 Lplunc1Q611143
Brain-specific serine protease 4 (Protease, serine, 22)Prss22 mCG_147772Q7TML03
Breakpoint cluster region protein (EC 2.7.11.1)Bcr Kiaa3017Q6PAJ13
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 (Brefeldin A-inhibited GEP 2) (ADP-ribosylation factor guanine nucleotide-exchange factor 2)Arfgef2 Arfgep2 Big2A2A5R23
BRISC complex subunit Abro1 (Abraxas brother protein 1) (Protein FAM175B)Fam175b Abro1 Kiaa0157Q3TCJ13
Bromodomain adjacent to zinc finger domain protein 1A (Cbp146)Baz1a Cbp146O883793
Bromodomain and WD repeat domain containing 2, isoform CRA_a (WD repeat-containing protein 11)Wdr11 Brwd2 mCG_22163G5E8J33
Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP)Brd4 McapQ9ESU63
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1)Kctd13 Poldip1Q8BGV73
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3Kctd10F8WGQ93
BTB/POZ domain-containing protein 17 (Galectin-3-binding protein-like)Btbd17Q9DB723
BTB/POZ domain-containing protein KCTD12Kctd12A0A0R4J2B23
C-C motif chemokine 2 (Monocyte chemoattractant protein 1) (Monocyte chemotactic protein 1) (MCP-1) (Platelet-derived growth factor-inducible protein JE) (Small-inducible cytokine A2)Ccl2 Je Mcp1 Scya2P101483
C-type lectin domain family 10 member A (MMGL) (Macrophage asialoglycoprotein-binding protein 1) (M-ASGP-BP-1) (Macrophage galactose/N-acetylgalactosamine-specific lectin)Clec10a Mgl Mgl1P493003
C-type lectin domain family 11 member A (Lymphocyte secreted C-type lectin) (Osteolectin) (Stem cell growth factor)Clec11a ScgfO882003
C-X-C motif chemokine 15 (Lungkine) (Small-inducible cytokine B15)Cxcl15 Scyb15Q9WVL73
C2 domain-containing protein 5C2cd5 5730419I09RikE9Q0263
CAAX prenyl protease 1 homolog (EC 3.4.24.84) (Farnesylated proteins-converting enzyme 1) (FACE-1) (Prenyl protein-specific endoprotease 1) (Zinc metalloproteinase Ste24 homolog)Zmpste24 Face1Q80W543
CactinCactinQ9CS003
Cadherin EGF LAG seven-pass G-type receptor 1Celsr1O351613
Cadherin EGF LAG seven-pass G-type receptor 2Celsr2 mCG_4064A2AEE73
Cadherin-11 (OSF-4) (Osteoblast cadherin) (OB-cadherin)Cdh11 Cad-11P552883
Cadherin-4 (Retinal cadherin) (R-CAD) (R-cadherin)Cdh4P390383
Calcium-transporting ATPase (EC 3.6.3.8)Atp2c1Q8BMS73
Calcium-transporting ATPase type 2C member 1 (ATPase 2C1) (EC 3.6.3.8) (ATP-dependent Ca(2+) pump PMR1)Atp2c1 Pmr1Q80XR23
Calpain small subunit 1Capns1A0A0R4J1C23
Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2)Capns2Q9D7J73
Calpastatin (Calpain inhibitor)CastP511253
Calumenin (Calumenin, isoform CRA_b) (Cardiac calumenin isoform) (Putative uncharacterized protein)Calu mCG_9131Q6XLQ83
Canalicular multispecific organic anion transporter 2 (ATP-binding cassette sub-family C member 3) (Multidrug resistance-associated protein 3)Abcc3 Cmoat2 Mrp3B2RX123
CAP-Gly domain-containing linker protein 1Clip1D3Z2Z13
CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 170) (CLIP-170) (Restin)Clip1 Kiaa4046 RsnQ922J33
Carbohydrate sulfotransferase 14 (EC 2.8.2.35) (Dermatan 4-sulfotransferase 1) (D4ST-1)Chst14 D4st1Q80V533
Carboxypeptidase (EC 3.4.16.-)Ctsa Ppgb mCG_17533G3X8T33
Carboxypeptidase M (CPM) (EC 3.4.17.12)CpmQ80V423
Carnitine O-acetyltransferase (Carnitine acetylase) (EC 2.3.1.7) (Carnitine acetyltransferase) (CAT) (CrAT)CratP479343
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A)Cpt1a Cpt-1 Cpt1P977423
Casein kinase II subunit beta (CK II beta) (Fragment)Csnk2bG3UZJ53
Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2)Card14 Bimp2Q99KF03
Caspase-6 (CASP-6) (EC 3.4.22.59) (Apoptotic protease Mch-2) [Cleaved into: Caspase-6 subunit p18; Caspase-6 subunit p11]Casp6O087383
Cation-transporting ATPase 13A2 (EC 3.6.3.-)Atp13a2Q9CTG63
Cationic amino acid transporter 2 (CAT-2) (CAT2) (20.5) (Low affinity cationic amino acid transporter 2) (Solute carrier family 7 member 2) (T-cell early activation protein) (TEA)Slc7a2 Atrc2 TeaP185813
Caveolin-2Cav2Q9WVC33
CCR4-NOT transcription complex subunit 1 (Cnot1 protein)Cnot1B7ZWL13
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