EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
CDC23 (Cell division cycle 23, yeast, homolog), isoform CRA_a (Cell division cycle protein 23 homolog)Cdc23 mCG_123924G3X8W73
CDC42 small effector protein 1Cdc42se1Q8BHL73
CDC42 small effector protein 2Cdc42se2Q8BGH73
CEA-related cell adhesion molecule 1, isoform 1/2L (Carcinoembryonic antigen-related cell adhesion molecule 1)Ceacam1 CEACAM1a-2LQ3LFS93
Cell division cycle protein 20 homolog (mmCdc20) (p55CDC)Cdc20Q9JJ663
Centrin-2 (Fragment)Cetn2B1AUQ73
Centromere protein J (CENP-J)CenpjQ569L83
Centromere protein V (CENP-V) (Proline-rich protein 6)Cenpv Prr6Q9CXS43
Centromere-associated protein ECenpeE9QKK13
Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin superfamily protein 10) (KIF10) (Motor domain of KIF10)CenpeQ6RT243
Centrosomal protein of 170 kDa (Cep170)Cep170 Kiaa0470Q6A0653
CeruloplasminCpE9PZD83
cGMP-dependent protein kinase 1 (cGK 1) (cGK1) (EC 2.7.11.12) (cGMP-dependent protein kinase I) (cGKI)Prkg1 Prkg1b Prkgr1a Prkgr1bP0C6053
Chloride channel, nucleotide-sensitive, 1A (Chloride channel, nucleotide-sensitive, 1A, isoform CRA_b) (Methylosome subunit pICln) (Putative uncharacterized protein)Clns1a mCG_7058Q923F13
Chloride intracellular channel protein 3Clic3Q9D7P73
Choline transporter-like protein 1Slc44a1A2AMH43
Choline transporter-like protein 4 (Solute carrier family 44 member 4) (Thiamine pyrophosphate transporter 1) (mTPPT1)Slc44a4 Ctl4 Ng22 TPPT1Q91VA13
Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-I p150)Chaf1a Caip150Q9QWF03
Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-I p60)Chaf1bQ9D0N73
Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein)Cbx1 CbxP839173
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Axis duplication inhibitor) (Duplin)Chd8 Kiaa1564Q09XV53
Clathrin interactor 1 (MCG22297, isoform CRA_b)Clint1 mCG_22297Q5SUH63
Claudin-12Cldn12Q9ET433
Claudin-18Cldn18P568573
Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (CPSF 160 kDa subunit)Cpsf1 Cpsf160Q9EPU43
Cleavage and polyadenylation specificity factor subunit 7Cpsf7Q8BTV23
Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50)Cstf1Q99LC23
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1)Clasp1 Kiaa0622Q80TV83
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (Alpha 2,3-ST 4) (Beta-galactoside alpha-2,3-sialyltransferase 4) (EC 2.4.99.-) (Alpha 2,3-sialyltransferase IV) (Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase) (ST3Gal IV) (ST3GalIV) (Sialyltransferase 4C) (SIAT4-C)St3gal4 Siat4cQ91Y743
Coiled-coil domain-containing protein 124Ccdc124Q9D8X23
Coiled-coil domain-containing protein 167Ccdc167Q9D1623
Coiled-coil domain-containing protein 93Ccdc93E9QAD43
Coiled-coil domain-containing protein 96Ccdc96Q9CR923
Col4a5 protein (Collagen, type IV, alpha 5) (Putative uncharacterized protein)Col4a5Q63ZW63
Collagen alpha-1(VIII) chain [Cleaved into: Vastatin]Col8a1Q007803
Collagen alpha-1(XI) chainCol11a1Q612453
Collagen alpha-1(XIV) chainCol14a1Q80X193
Collectin-12 (Collectin placenta protein 1) (CL-P1) (Scavenger receptor with C-type lectin)Colec12 Clp1 SrclQ8K4Q83
COMM domain-containing protein 9Commd9Q8K2Q03
Complement C1r-B subcomponent (EC 3.4.21.41) (Complement component 1 subcomponent r-B) [Cleaved into: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain]C1rb C1rQ8CFG93
Complement C2 (EC 3.4.21.43) (C3/C5 convertase) [Cleaved into: Complement C2b fragment; Complement C2a fragment]C2P211803
Complement component C8 gamma chainC8gQ8VCG43
Complement decay-accelerating factor, GPI-anchored (DAF-GPI) (CD antigen CD55)Cd55 Cd55a Daf Daf1Q614753
Conserved oligomeric Golgi complex subunit 3 (COG complex subunit 3) (Component of oligomeric Golgi complex 3)Cog3Q8CI043
Conserved oligomeric Golgi complex subunit 6 (COG complex subunit 6) (Component of oligomeric Golgi complex 6)Cog6 Kiaa1134Q8R3I33
Conserved oligomeric Golgi complex subunit 7 (COG complex subunit 7) (Component of oligomeric Golgi complex 7)Cog7Q3UM293
Conserved oligomeric Golgi complex subunit 8 (COG complex subunit 8) (Component of oligomeric Golgi complex 8)Cog8 MNCb-5704Q9JJA23
COP9 signalosome complex subunit 1 (G protein pathway suppressor 1)Gps1Q3MIA83
COP9 signalosome complex subunit 1 (MCG2137, isoform CRA_b)Gps1 mCG_2137G3UXW93
COP9 signalosome complex subunit 6Cops6D3Z0F53
Copine-2Cpne2A0A0R4J1D03
Copine-6 (Copine VI) (Neuronal-copine) (N-copine)Cpne6Q9Z1403
Copine-6 (Putative uncharacterized protein)Cpne6Q3UYN23
Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone)Ccs CcsdQ9WU843
Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (M-CK)Ckm CkmmP073103
CST complex subunit CTC1 (Alpha-accessory factor of 132 kDa) (AAF-132) (AAF132) (Conserved telomere maintenance component 1)Ctc1Q5SUQ93
cTAGE family member 5 (Protein cTAGE-5) (Meningioma-expressed antigen 6)Ctage5 Mea6 Mgea6Q8R3113
CWF19-like protein 1Cwf19l1Q8CI333
Cyclin Y-like 1Ccnyl1D3YUJ33
Cyclin-dependent kinase 11B (Cell division cycle 2-like protein kinase 1) (Cell division protein kinase 11) (Cyclin-dependent kinase 11) (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1)Cdk11b Cdc2l1 Cdk11P247883
Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12)Cdk12 Crk7 Crkrs Kiaa0904Q14AX63
Cyclin-dependent kinase 13 (EC 2.7.11.22) (EC 2.7.11.23) (CDC2-related protein kinase 5) (Cell division cycle 2-like protein kinase 5) (Cell division protein kinase 13)Cdk13 Cdc2l5 Kiaa1791Q69ZA13
Cyclin-dependent kinase 16 (EC 2.7.11.22) (CRK5) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)Cdk16 Crk5 Pctaire1 Pctk1Q047353
Cyclin-dependent kinases regulatory subunit 1 (CKS-1) (Sid 1334)Cks1b Cks1 Sid1334P610253
Cyclin-HCcnhQ614583
Cystatin (Fragment)Cst3A2APX33
Cytochrome b-c1 complex subunit 7 (Complex III subunit 7) (Complex III subunit VII) (Ubiquinol-cytochrome c reductase complex 14 kDa protein)UqcrbQ9D8553
Cytochrome c oxidase subunit NDUFA4Ndufa4A0A0N4SVQ13
Cytochrome P450 20A1 (EC 1.14.-.-)Cyp20a1Q8BKE63
Cytochrome P450 2A5 (EC 1.14.14.1) (CYPIIA5) (Coumarin 7-hydroxylase) (Cytochrome P450-15-COH) (Cytochrome P450-IIA3.2)Cyp2a5 Cyp2a-5P208523
Cytochrome P450 2B10 (EC 1.14.14.1) (CYPIIB10) (CYPIIB20) (Cytochrome P450 2B20) (Cytochrome P450 clone PF3/46) (Cytochrome P450-16-alpha) (P24) (Testosterone 16-alpha hydroxylase)Cyp2b10 Cyp2b-10 Cyp2b20P127913
Cytochrome P450 4B1 (EC 1.14.14.1) (CYPIVB1)Cyp4b1Q644623
Cytohesin-2 (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2) (CLM2) (SEC7 homolog B) (mSec7-2)Cyth2 Pscd2 Sec7bP630343
Cytosolic Fe-S cluster assembly factor NUBP1 (Nucleotide-binding protein 1) (NBP 1)Nubp1Q9R0603
Cytospin-B (Sperm antigen with calponin homology and coiled-coil domains 1)Specc1 Cytsb Kiaa4061Q5SXY13
DAZ associated protein 1, isoform CRA_b (DAZ-associated protein 1) (Putative uncharacterized protein)Dazap1 mCG_142352Q3UGB53
DBH-like monooxygenase protein 1 (EC 1.14.17.-) (DBH-related protein) (Monooxygenase X)Moxd1 Dbhr MoxQ9CXI33
DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2)Appl2 Dip13b Dip3bQ8K3G93
DDB1- and CUL4-associated factor 1 (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1)Dcaf1 Kiaa0800 VprbpQ80TR83
DDB1- and CUL4-associated factor 8 (WD repeat-containing protein 42A)Dcaf8 D1Ucla4 H326 Wdr42aQ8N7N53
Dedicator of cytokinesis protein 11Dock11A2AF673
Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1)Dock9 D14Wsu89e Kiaa1058 Ziz1Q8BIK43
Dehydrodolichyl diphosphate synthase complex subunit Dhdds (EC 2.5.1.87) (Cis-isoprenyltransferase) (CIT) (Cis-IPTase)DhddsQ99KU13
DENN domain-containing protein 4CDennd4cA6H8H23
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1Samhd1F8WJE03
Deoxynucleotidyltransferase terminal-interacting protein 2Dnttip2Q8R2M23
DEP domain-containing mTOR-interacting protein (DEP domain-containing protein 6)Deptor Depdc6 Kiaa4200Q570Y93
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (Der1-like protein 1)Derl1 Der1Q99J563
Deubiquitinating protein VCIP135 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135)Vcpip1 Vcip135Q8CDG33
Diacylglycerol kinase (DAG kinase) (EC 2.7.1.107)DgkhD3YXJ03
Diacylglycerol kinase (DAG kinase) (EC 2.7.1.107)DgkdE9PUQ83
Diacylglycerol kinase zeta (DAG kinase zeta) (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta)DgkzQ80UP33
Digestive organ expansion factor homologDiexf DefQ8BTT63
Dimethylaniline monooxygenase [N-oxide-forming] 3 (EC 1.14.13.8) (Dimethylaniline oxidase 3) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Trimethylamine monooxygenase) (EC 1.14.13.148)Fmo3P975013
Dipeptidyl peptidase 2 (EC 3.4.14.2) (Dipeptidyl aminopeptidase II) (Dipeptidyl peptidase 7) (Dipeptidyl peptidase II) (DPP II) (Quiescent cell proline dipeptidase)Dpp7 Dpp2 QppQ9ET223
Disks large homolog 1Dlg1S4R2T83
Disks large homolog 3Dlg3A2BEF23
DmX-like protein 2 (Rabconnectin-3)Dmxl2 Kiaa0856Q8BPN83
DNA dC->dU-editing enzyme APOBEC-3 (EC 3.5.4.-) (Apolipoprotein B mRNA-editing complex 3) (Arp3) (CEM-15) (CEM15)Apobec3Q99J723
DNA helicase B (EC 3.6.4.12)HelbQ6NVF43
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