EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
P protein (Melanocyte-specific transporter protein) (Pink-eyed dilution protein)Oca2 PQ620523
PalladinPalld Kiaa0992Q9ET543
Pannexin-1Panx1Q9JIP43
Parkinson disease 7 domain-containing protein 1Pddc1Q8BFQ83
PaxillinPxnF8VQ283
PEAK1-related kinase-activating pseudokinase 1Prag1 D8Ertd82eE9QLH93
Peptidyl-prolyl cis-trans isomerase G (PPIase G) (Peptidyl-prolyl isomerase G) (EC 5.2.1.8) (Cyclophilin G) (Rotamase G)PpigA2AR023
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 (EC 5.2.1.8) (Parvulin-14) (Par14) (Peptidyl-prolyl cis-trans isomerase Pin4) (PPIase Pin4) (Rotamase Pin4)Pin4Q9CWW63
Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (EC 5.2.1.8)Ppwd1Q8CEC63
Peroxiredoxin-5, mitochondrialPrdx5G3UZJ43
Peroxisomal bifunctional enzyme (PBE) (PBFE) [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase (EC 4.2.1.17) (EC 5.3.3.8); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]EhhadhQ9DBM23
Peroxisome biogenesis factor 1 (Peroxin-1)Pex1Q5BL073
PH-interacting protein (PHIP) (IRS-1 PH domain-binding protein) (Neuronal differentiation-related protein) (NDRP) (WD repeat-containing protein 11)Phip Ndrp Phip1 Wdr11Q8VDD93
Phosphatidate cytidylyltransferase 2 (EC 2.7.7.41) (CDP-DAG synthase 2) (CDP-DG synthase 2) (CDP-diacylglycerol synthase 2) (CDS 2) (CDP-diglyceride pyrophosphorylase 2) (CDP-diglyceride synthase 2) (CTP:phosphatidate cytidylyltransferase 2)Cds2Q99L433
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)Pten Mmac1O085863
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphoinositide-3-kinase class 3)Pik3c3 Vps34Q6PF933
Phosphatidylinositol transfer protein alpha isoformPitpnaJ3QPW13
Phosphofurin acidic cluster sorting protein 1 (PACS-1)Pacs1Q8K2123
Phospholipase B-like 1 (EC 3.1.1.-) (LAMA-like protein 1) (Lamina ancestor homolog 1) (Phospholipase B domain-containing protein 1) [Cleaved into: Phospholipase B-like 1 chain A; Phospholipase B-like 1 chain B; Phospholipase B-like 1 chain C]Plbd1Q8VCI03
Phospholipase D4 (PLD 4) (EC 3.1.4.4) (Choline phosphatase 4) (Phosphatidylcholine-hydrolyzing phospholipase D4)Pld4Q8BG073
Phospholipid transfer protein C2CD2L (C2 domain-containing protein 2-like) (Transmembrane protein 24)C2cd2l Tmem24Q80X803
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp9bD3YV003
Phosphomannomutase 1 (PMM 1) (EC 5.4.2.8)Pmm1O356213
Phosphomevalonate kinase (PMKase) (EC 2.7.4.2)PmvkQ9D1G23
Phosphorylated adapter RNA export protein (RNA U small nuclear RNA export adapter protein)Phax RnuxaQ9JJT93
Pituitary tumor-transforming gene 1 protein-interacting protein (Fragment)Pttg1ipE0CXB53
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor)PdgfrbE9QPE23
Pleckstrin homology domain-containing family A member 2 (PH domain-containing family A member 2) (PH domain-containing adaptor PHAD47) (Tandem PH domain-containing protein 2) (TAPP-2)Plekha2 Tapp2Q9ERS53
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7) (Heart adapter protein 1)Plekha7 Hadp1Q3UIL63
Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3)Plekhg3 Kiaa0599Q4VAC93
Pleckstrin homology-like domain family A member 1 (Proline- and glutamine-rich protein) (PQ-rich protein) (PQR protein) (T-cell death-associated gene 51 protein)Phlda1 Tdag51Q623923
Pleckstrin homology-like domain, family B, member 3Phldb3E9QAF43
Plexin-A4Plxna4 Kiaa1550Q80UG23
Podocalyxin (Podocalyxin-like protein 1) (PC) (PCLP-1)Podxl Pclp1Q9R0M43
Podoplanin (Glycoprotein 38) (Gp38) (OTS-8) (PA2.26 antigen) (Transmembrane glycoprotein E11) (E11)Pdpn Gp38 Ots8Q620113
Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (msPARP)Parp1 Adprp Adprt Adprt1P111033
Poly(A) polymerase alpha (PAP-alpha) (EC 2.7.7.19) (Polynucleotide adenylyltransferase)Papola Pap PlapQ611833
Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143)PargO886223
Poly(rC)-binding protein 4Pcbp4A0A0R4J0443
Polyadenylate-binding protein (PABP)Pabpc4Q99LF83
Polyadenylate-binding protein (PABP)Pabpc2 mCG_13635Q620293
Polyadenylate-binding protein-interacting protein 1Paip1D3Z3J63
Pre-B-cell leukemia transcription factor-interacting protein 1 (Hematopoietic PBX-interacting protein)Pbxip1 HpipQ3TVI83
Pre-mRNA-processing factor 17 (Cell division cycle 40 homolog) (PRP17 homolog)Cdc40 Prp17 Prpf17Q9DC483
Pre-mRNA-splicing factor ISY1 homologIsy1 Kiaa1160Q69ZQ23
Prefoldin 4Pfdn4Q6P0X13
Prefoldin subunit 6 (Protein Ke2)Pfdn6 H2-Ke2 Pfd6Q039583
Prenylcysteine oxidase-like (EC 1.8.3.-)Pcyox1lQ8C7K63
Presenilin (EC 3.4.23.-)Psen2A0A0R4J1F23
Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52)Ddx52 Rok1Q8K3013
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)Ciao1 Wdr39Q99KN23
Probable E3 ubiquitin-protein ligase DTX3 (EC 2.3.2.27) (Protein deltex-3) (Deltex3) (mDTX3) (RING-type E3 ubiquitin transferase DTX3)Dtx3Q80V913
Probable E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase makorin-2)Mkrn2Q9ERV13
Probable phospholipid-transporting ATPase IH (EC 3.6.3.1) (ATPase IS) (ATPase class VI type 11A) (P4-ATPase flippase complex alpha subunit ATP11A)Atp11aP981973
Probable phospholipid-transporting ATPase IIB (EC 3.6.3.1) (ATPase class II type 9B)Atp9bP981953
Probable ribosome biogenesis protein RLP24 (Ribosomal L24 domain-containing protein 1) (Ribosomal protein L24-like)Rsl24d1Q99L283
Probable tRNA N6-adenosine threonylcarbamoyltransferase (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein Osgep) (tRNA threonylcarbamoyladenosine biosynthesis protein Osgep)OsgepQ8BWU53
Programmed cell death protein 4 (Protein MA-3) (Topoisomerase-inhibitor suppressed protein)Pdcd4 Ma3 TisQ618233
Prolactin-2C3 (Mitogen-regulated protein 2) (Mitogen-regulated protein 3) (Prolactin-2C4) (Proliferin-2) (Proliferin-3)Prl2c3 Mrp2 Mrp3 Mrpplf3 Plf2 Plf3 Prl2c4P047683
Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting protein 1)Pstpip1P978143
Prolyl 3-hydroxylase 1 (EC 1.14.11.7) (Growth suppressor 1) (Leucine- and proline-enriched proteoglycan 1) (Leprecan-1)P3h1 Gros1 Lepre1Q3V1T43
Prolyl 3-hydroxylase 2 (EC 1.14.11.7) (Leprecan-like protein 1)P3h2 Leprel1Q8CG713
Prolyl 4-hydroxylase subunit alpha-2 (4-PH alpha-2) (EC 1.14.11.2) (Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-2)P4ha2Q607163
Prostaglandin G/H synthase 1 (EC 1.14.99.1) (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1)Ptgs1 Cox-1 Cox1P224373
Prostasin (EC 3.4.21.-) (Channel-activating protease 1) (CAP1) (Serine protease 8) [Cleaved into: Prostasin light chain; Prostasin heavy chain]Prss8 Cap1Q9ESD13
Prostasin (Protease, serine, 8 (Prostasin))Prss8Q99L443
Protein arginine N-methyltransferase 8 (EC 2.1.1.-) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4)Prmt8 Hrmt1l4Q6PAK33
Protein CASC3 (Cancer susceptibility candidate gene 3 protein homolog) (Metastatic lymph node gene 51 protein homolog) (MLN 51 homolog) (Protein barentsz) (Btz) (mBtz)Casc3 Mln51Q8K3W33
Protein CDV3 (Carnitine deficiency-associated protein 3) (Tyrosine-phosphorylated protein 36) (TPP36)Cdv3Q4VAA23
Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3)Diaph2 Diap2O705663
Protein diaphanous homolog 3Diaph3F8WIG53
Protein disulfide-isomerase A6 (Putative uncharacterized protein)Pdia6Q3TML03
Protein FAM111AFam111a Kiaa1895Q9D2L93
Protein FAM126BFam126b D1Ertd53eQ8C7293
Protein FAM134CFam134cQ9CQV43
Protein FAM198B (Expressed in nerve and epithelium during development)Fam198b EnedQ3UPI13
Protein FAM3C (Interleukin-like EMT inducer)Fam3c D6Wsu176e IleiQ91VU03
Protein GPR107Gpr107 Kiaa1624Q8BUV83
Protein HEG homolog 1Heg1E9Q7X63
Protein Hook homolog 3 (mHK3)Hook3Q8BUK63
Protein inscuteable homolog (RIKEN cDNA 3830422K02, isoform CRA_c)Insc 3830422K02Rik mCG_7306G3UW773
Protein KHNYN (KH and NYN domain-containing protein)Khnyn Kiaa0323Q80U383
Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon)Prkce Pkce PkceaP160543
Protein kinase C iota type (EC 2.7.11.13) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (nPKC-iota)Prkci PkclQ620743
Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)Prkcq PkcqQ021113
Protein kish-A (Transmembrane protein 167) (Transmembrane protein 167A)Tmem167a Tmem167Q9CR643
Protein KTI12 homologKti12Q9D1R23
Protein lifeguard 3 (Fragment)Tmbim1D3Z0A53
Protein lifeguard 3 (Putative uncharacterized protein) (Transmembrane BAX inhibitor motif containing 1, isoform CRA_b)Tmbim1 mCG_114808Q3U7173
Protein mago nashi homolog 2Magohb Magoh-rs1 Magoh2Q9CQL13
Protein misato homolog 1Msto1E9PUB73
Protein NipSnap homolog 1 (NipSnap1)Nipsnap1O551253
Protein NipSnap homolog 3B (NipSnap3B) (NipSnap-related protein) (Protein NipSnap homolog 3A) (NipSnap3A)Nipsnap3b Nipsnap3aQ9CQE13
Protein O-glucosyltransferase 1 (EC 2.4.1.-) (CAP10-like 46 kDa protein) (KTEL motif-containing protein 1) (O-glucosyltransferase Rumi homolog) (Rumi) (Protein O-xylosyltransferase POGLUT1) (EC 2.4.2.26) (Wing-shaped neural plate protein) (Wsnp)Poglut1 Clp46 Ktelc1Q8BYB93
Protein phosphatase 1 regulatory subunit 14B (Phosphatase holoenzyme inhibitor 1) (PHI-1) (Phospholipase C-beta-3 neighbouring gene protein)Ppp1r14b PngQ620843
Protein phosphatase 1, regulatory (inhibitor) subunit 9APpp1r9aH3BKQ73
Protein phosphatase 1F (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase) (CaM-kinase phosphatase) (CaMKPase)Ppm1fQ8CGA03
Protein PRRC2A (HLA-B-associated transcript 2) (Proline-rich and coiled-coil-containing protein 2A)Prrc2a Bat2Q7TSC13
Protein regulator of cytokinesis 1Prc1G3UWQ73
Protein RMD5 homolog ARmnd5aQ80YQ83
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