EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Trafficking protein particle complex 8Trappc8E9PWG23
Trafficking protein particle complex 8Trappc8E9PY513
Trafficking protein particle complex subunit 4 (Synbindin) (TRS23 homolog)Trappc4 SbdnQ9ES563
Transcription elongation factor SPT6Supt6h Kiaa0162 Supt6Q623833
Transcription elongation regulator 1 (Formin-binding protein 28) (FBP 28) (TATA box-binding protein-associated factor 2S) (Transcription factor CA150) (p144)Tcerg1 Taf2sQ8CGF73
Transcription factor BTF3 (Nascent polypeptide-associated complex subunit beta) (NAC-beta) (RNA polymerase B transcription factor 3)Btf3Q641523
Transcription factor COE2 (Early B-cell factor 2) (EBF-2) (Metencephalon-mesencephalon-olfactory transcription factor 1) (MET-mesencephalon-olfactory TF1) (MET-mesencephalon-olfactory transcription factor 1) (Olf-1/EBF-like 3) (O/E-3) (OE-3)Ebf2 Coe2 Mmot1O087923
Transcription initiation factor IIB (General transcription factor TFIIB) (RNA polymerase II alpha initiation factor)Gtf2bP629153
Transcription initiation factor TFIID subunit 9 (RNA polymerase II TBP-associated factor subunit G) (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII31) (Transcription initiation factor TFIID 32 kDa subunit) (TAFII-32) (TAFII32)Taf9 Taf2gQ8VI333
Transcription termination factor 1 (TTF-1) (RNA polymerase I termination factor) (Transcription termination factor I) (TTF-I) (mTFF-I)Ttf1Q621873
Transcription termination factor 2 (EC 3.6.4.-) (RNA polymerase II termination factor) (Transcription release factor 2)Ttf2Q5NC053
Transgelin-3 (Neuronal protein NP25)Tagln3 Np25Q9R1Q83
Transient receptor potential cation channel subfamily M member 7Trpm7A2AI573
Translin-associated protein X (Translin-associated factor X)Tsnax TraxQ9QZE73
Translocation protein SEC63 homologSec63 Sec63lQ8VHE03
Transmembrane 7 superfamily member 3 (NARP1)Tm7sf3Q9CRG13
Transmembrane and TPR repeat-containing protein 3Tmtc3Q8BRH03
Transmembrane channel-like protein 6Tmc6Q7TN603
Transmembrane gamma-carboxyglutamic acid protein 4 (Proline-rich gamma-carboxyglutamic acid protein 4) (Proline-rich Gla protein 4)Prrg4 Prgp4 Tmg4Q8BGN63
Transmembrane p24-trafficking protein 7Tmed7E9Q7G13
Transmembrane protein 106ATmem106aQ8VC043
Transmembrane protein 120A (Transmembrane protein induced by tumor necrosis factor alpha)Tmem120a Net29 TmpitQ8C1E73
Transmembrane protein 126ATmem126aQ9D8Y13
Transmembrane protein 222Tmem222 D4Ertd196eQ8BVA23
Transmembrane protein 268 (Fragment)Tmem268 6330416G13RikZ4YMT73
Transmembrane protein 51Tmem51Q99LG13
Transmembrane protein 87ATmem87aQ8BXN93
TRIO and F-actin-binding proteinTriobpE9QMQ33
TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin)Triobp Kiaa1662 TaraQ99KW33
Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)]Tkfc DakQ8VC303
Tripartite motif-containing protein 14 (PU.1-binding protein)Trim14 Kiaa0129 PubQ8BVW33
TRMT1-like protein (EC 2.1.1.-)Trmt1lA2RSY63
tRNA (guanine(26)-N(2))-dimethyltransferase (EC 2.1.1.216) (tRNA 2,2-dimethylguanosine-26 methyltransferase) (tRNA(guanine-26,N(2)-N(2)) methyltransferase) (tRNA(m(2,2)G26)dimethyltransferase)Trmt1 D8Ertd812eQ3TX083
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 (WD repeat-containing protein 4)Wdr4Q9EP823
tRNA pseudouridine synthase A, mitochondrial (EC 5.4.99.12) (tRNA pseudouridine(38-40) synthase) (tRNA pseudouridylate synthase I) (tRNA-uridine isomerase I)Pus1 MNCb-0873Q9WU563
Tropomyosin alpha-1 chainTpm1E9Q4503
Tropomyosin beta chainTpm2A2AIM43
Tubulin alpha chain (Fragment)Tuba4aA0A0A0MQA53
Tubulin-folding cofactor B (Cytoskeleton-associated protein 1) (Cytoskeleton-associated protein CKAPI) (Tubulin-specific chaperone B)Tbcb Ckap1Q9D1E63
Tubulin-specific chaperone E (Tubulin-folding cofactor E)TbceQ8CIV83
Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b)Tnfrsf1b Tnfr-2 Tnfr2P251193
Tumor necrosis factor receptor superfamily member 22 (Decoy TRAIL receptor 2) (TNF receptor family member SOBa) (TNF receptor homolog 2) (Tumor necrosis factor receptor p60 homolog 2)Tnfrsf22 Dctrailr2 Tnfrh2 Tnfrsf1al2Q9ER623
Tumor necrosis factor receptor superfamily member 23 (Decoy TRAIL receptor 1) (TNF receptor family member SOB) (TNF receptor homolog 1) (Tumor necrosis factor receptor p60 homolog 1)Tnfrsf23 Dctrailr1 Tnfrh1 Tnfrsf1al1Q9ER633
Tumor necrosis factor receptor superfamily member 26 (TNF receptor homolog 3)Tnfrsf26 Tnfrh3P836263
Tumor necrosis factor receptor superfamily member 5 (B-cell surface antigen CD40) (Bp50) (CD40L receptor) (CD antigen CD40)Cd40 Tnfrsf5P275123
Tumor protein D54Tpd52l2A2AUD53
Type VI collagen alpha 3 subunitCol6a3O884933
Tyrosine--tRNA ligase (EC 6.1.1.1) (Tyrosyl-tRNA synthetase)Yars mCG_141662A2A7S73
Tyrosine-protein kinase (EC 2.7.10.2)Abl2B2RQ573
Tyrosine-protein kinase (EC 2.7.10.2)SrcF8WI903
Tyrosine-protein kinase (EC 2.7.10.2)Jak2 mCG_9104G5E8523
Tyrosine-protein phosphatase non-receptor type 9 (EC 3.1.3.48) (Protein-tyrosine phosphatase MEG2) (PTPase MEG2)Ptpn9O352393
Tyrosine-protein phosphatase non-receptor type substrate 1SirpaE0CX653
U3 small nucleolar ribonucleoprotein protein IMP4 (U3 snoRNP protein IMP4)Imp4 D1Wsu40eQ8VHZ73
U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein)Utp14a JsdX Kiaa0266Q640M13
U3 small nucleolar RNA-associated protein 4 homolog (Cirhin) (Testis-expressed gene 292 protein)Utp4 Cirh1a Kiaa1988 Tex292Q8R2N23
U3 small nucleolar RNA-associated protein 6 homolog (Multiple hat domains protein)Utp6 MhatQ8VCY63
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1)Ubqln1 Plic1Q8R3173
Ubiquitin associated protein 2-like, isoform CRA_b (Ubiquitin-associated protein 2-like)Ubap2l mCG_22226A0A0H2UH173
Ubiquitin carboxyl-terminal hydrolase 14Usp14E9PYI83
Ubiquitin carboxyl-terminal hydrolase 16 (EC 3.4.19.12) (Deubiquitinating enzyme 16) (Ubiquitin thioesterase 16) (Ubiquitin-specific-processing protease 16)Usp16Q99LG03
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19)Usp19 Kiaa0891Q3UJD63
Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)Usp34 Kiaa0570 Murr2Q6ZQ933
Ubiquitin carboxyl-terminal hydrolase 46Usp46D3YVU03
Ubiquitin recognition factor in ER-associated degradation protein 1 (Ubiquitin fusion degradation protein 1 homolog) (UB fusion protein 1)Ufd1 Ufd1lP703623
Ubiquitin-associated protein 1 (UBAP-1)Ubap1Q8BH483
Ubiquitin-conjugating enzyme E2 CUbe2cA2A4Z13
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UBCH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)Ube2hP622573
Ubiquitin-like modifier-activating enzyme 1 Y (EC 6.2.1.45) (Ubiquitin-activating enzyme E1) (Ubiquitin-activating enzyme E1 Y)Uba1y Sby Ube1ay Ube1y Ube1y1P312543
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)Uba5 Ube1dc1Q8VE473
Ubiquitin-like modifier-activating enzyme 6Uba6D3Z0613
UBX domain-containing protein 6 (UBX domain-containing protein 1)Ubxn6 Ubxd1 Ubxdc2Q99PL63
UHRF1 (ICBP90)-binding protein 1Uhrf1bp1B2KF503
Uncharacterized proteinTpm3-rs7D3Z2H93
Uncharacterized proteinGm10260 Gm17352F6YVP73
Uncharacterized proteinGm9242J3QNY13
Uncharacterized proteinGm10036E9PYL93
Uncharacterized proteinGm20547 C2B8JJN03
Uridine phosphorylase (EC 2.4.2.3)Upp2Q8R0933
Uridine phosphorylase 1 (UPase 1) (UrdPase 1) (EC 2.4.2.3)Upp1 Up UppP526243
Uteroglobin (Clara cell 17 kDa protein) (Clara cell phospholipid-binding protein) (CCPBP) (Clara cells 10 kDa secretory protein) (CC10) (PCB-binding protein) (Secretoglobin family 1A member 1)Scgb1a1 Cc10 Ugb UtgQ063183
Vacuolar protein sorting-associated protein 16 homolog (mVPS16)Vps16Q920Q43
Vacuolar protein sorting-associated protein 53 homologVps53E9PXG93
Vang-like protein 1Vangl1A0A0H2UH253
Vascular cell adhesion protein 1Vcam1Q3UPN13
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (CD antigen CD106)Vcam1 Vcam-1P295333
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)Flt4 Flt-4 Vegfr3P359173
Vasorin (Protein slit-like 2)Vasn Slitl2Q9CZT53
Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2)Vti1a Vti1 Vti1l2O891163
Vesicle-associated membrane protein 2Vamp2B0QZN53
Vesicle-associated membrane protein 4 (VAMP-4)Vamp4O704803
Vesicle-associated membrane protein 8 (Vesicle-associated membrane protein 8, isoform CRA_b)Vamp8 mCG_129303A0A0R4J0R13
Vomeromodulin (BPI fold-containing family B member 9A)Bpifb9aQ80XI73
WAS/WASL-interacting protein family member 2 (WASP-interacting protein-related protein) (WIP-related protein)Wipf2 WireQ6PEV33
WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45-like) (WDR45-like protein) (WD repeat-containing protein 45B)Wdr45b Wdr45l Wipi3Q9CR393
WD repeat-containing protein 26Wdr26E0CYH43
WD repeat-containing protein 73Wdr73Q9CWR13
WD repeat-containing protein 81 (Fragment)Wdr81K4DI773
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku autoantigen protein p86 homolog) (Ku80) (Nuclear factor IV)Xrcc5 G22p2P276413
Xenotropic and polytropic retrovirus receptor 1Xpr1D3Z2B43
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