EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Y+L amino acid transporter 1 (Solute carrier family 7 member 7) (y(+)L-type amino acid transporter 1) (Y+LAT1) (y+LAT-1)Slc7a7Q9Z1K83
YTH domain-containing family protein 1 (Dermatomyositis associated with cancer putative autoantigen 1 homolog) (DACA-1 homolog)Ythdf1P593263
YTH domain-containing family protein 2Ythdf2Q91YT73
YTH domain-containing protein 1Ythdc1 Kiaa1966E9Q5K93
Zinc finger CCCH domain-containing protein 11AZc3h11a Kiaa0663Q6NZF13
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)Zc3h18 Nhn1Q0P6783
Zinc finger CCCH-type antiviral protein 1-likeZc3hav1lQ8BFR13
Zinc finger CCHC domain-containing protein 8 (TRAMP-like complex RNA-binding factor ZCCHC8)Zcchc8Q9CYA63
Zinc finger FYVE domain-containing protein 26Zfyve26 Kiaa0321Q5DU373
Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem)Dpf2 Baf45d Req Ubid4Q611033
Zinc finger SWIM domain-containing protein 8Zswim8 Kiaa0913Q3UHH13
Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7)Slc39a7 H2-Ke4 Hke4Q311253
ZW10 interactor (ZW10-interacting protein 1) (Zwint-1)Zwint D10Ertd749eQ9CQU53
0610038D11Rik protein (MCG130245, isoform CRA_b) (Multifunctional methyltransferase subunit TRM112-like protein)Trmt112 0610038D11Rik mCG_130245Q8VCR42
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 1) (1-AGP acyltransferase 1) (1-AGPAT 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha)Agpat1O350832
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (EC 2.3.1.51) (Abhydrolase domain-containing protein 5) (Lipid droplet-binding protein CGI-58) (Protein CGI-58)Abhd5Q9DBL92
1-phosphatidylinositol 3-phosphate 5-kinasePikfyveD3Z5N52
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (EC 3.1.4.11) (PLC-154) (Phosphoinositide phospholipase C-beta-1) (Phospholipase C-beta-1) (PLC-beta-1)Plcb1 PlcbQ9Z1B32
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-epsilon-1) (Phospholipase C-epsilon-1) (PLC-epsilon-1)Plce1 Kiaa1516 PlceQ8K4S12
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (Ovarian cancer-associated gene 1 protein homolog) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)Dph1 Dph2l1 Ovca1Q5NCQ52
2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (AKB ligase) (EC 2.3.1.29) (Aminoacetone synthase) (Glycine acetyltransferase)Gcat KblO889862
2-iminobutanoate/2-iminopropanoate deaminase (EC 3.5.99.10) (Heat-responsive protein 12) (Reactive intermediate imine deaminase A homolog) (Translation inhibitor L-PSP ribonuclease) (EC 3.1.-.-)Rida Hrp12P527602
2410017P07Rik protein (Centrosomal protein CEP57L1)Cep57l1 2410017P07RikB2RR532
28S ribosomal protein S15, mitochondrial (MRP-S15) (S15mt)Mrps15 Rpms15Q9DC712
28S ribosomal protein S17, mitochondrial (MRP-S17) (S17mt)Mrps17 Rpms17Q9CQE32
28S ribosomal protein S23, mitochondrial (Fragment)Mrps23F7ARZ12
28S ribosomal protein S24, mitochondrial (MRP-S24) (S24mt)Mrps24Q9CQV52
28S ribosomal protein S25, mitochondrial (MRP-S25) (S25mt)Mrps25 Rpms25Q9D1252
28S ribosomal protein S30, mitochondrial (MRP-S30) (S30mt)Mrps30Q9D0G02
28S ribosomal protein S31, mitochondrial (MRP-S31) (S31mt) (Imogen 38)Mrps31 Imogn38Q617332
28S ribosomal protein S33, mitochondrial (MRP-S33) (S33mt) (Ganglioside-induced differentiation-associated-protein 3)Mrps33 Gdap3Q9D2R82
28S ribosomal protein S5, mitochondrial (MRP-S5) (S5mt)Mrps5Q99N872
28S ribosomal protein S6, mitochondrial (MRP-S6) (S6mt)Mrps6 Rpms6P580642
28S ribosomal protein S7, mitochondrial (MRP-S7) (S7mt)Mrps7Q80X852
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)HibchQ8QZS12
3-keto-steroid reductase (Putative uncharacterized protein)Hsd17b7Q8C5N92
39S ribosomal protein L1, mitochondrial (L1mt) (MRP-L1)Mrpl1Q99N962
39S ribosomal protein L1, mitochondrial (Putative uncharacterized protein)Mrpl1Q9D3F32
39S ribosomal protein L13, mitochondrial (Fragment)Mrpl13F7CXG92
39S ribosomal protein L14, mitochondrial (L14mt) (MRP-L14)Mrpl14Q9D1I62
39S ribosomal protein L18, mitochondrial (L18mt) (MRP-L18)Mrpl18Q9CQL52
39S ribosomal protein L19, mitochondrial (L19mt) (MRP-L19)Mrpl19Q9D3382
39S ribosomal protein L2, mitochondrial (Mitochondrial ribosomal protein L2, isoform CRA_c)Mrpl2 mCG_2358B1B1D72
39S ribosomal protein L20, mitochondrialMrpl20V9GXI72
39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37)Mrpl37Q921S72
39S ribosomal protein L40, mitochondrialMrpl40D3Z7C02
39S ribosomal protein L43, mitochondrial (Mitochondrial ribosomal protein L43)Mrpl43 mCG_16934Q5RL202
39S ribosomal protein L44, mitochondrial (L44mt) (MRP-L44) (EC 3.1.26.-)Mrpl44Q9CY732
39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50)Mrpl50Q8VDT92
40S ribosomal protein S10 (Putative uncharacterized protein)Rps10Q3UW832
40S ribosomal protein S15Rps15D3YTQ92
40S ribosomal protein S2Rps2D3YWJ32
40S ribosomal protein S2 (Fragment)Rps2D3YVC12
40S ribosomal protein S24Rps24Q9CQK22
40S ribosomal protein S27Rps27lD6RH492
40S ribosomal protein S4Rps4xQ545F82
43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein)RapsnP126722
45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4)Sdf4 Cab45Q611122
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (EC 2.7.11.27) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)Prkaa2Q8BRK82
5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) (Cytosolic 5'-nucleotidase II-like protein 1)Nt5dc1 Nt5c2l1Q8C5P52
5-azacytidine induced gene 1 (Centrosomal protein of 131 kDa)Cep131 Azi1B1AXI92
60S ribosomal protein L26Rpl26B1ARA52
60S ribosomal protein L29Gm17669F6QL702
60S ribosomal protein L36Rpl36Q5M9L12
60S ribosomal protein L39Rpl39P628922
A disintegrin and metalloproteinase with thrombospondin motifs 12 (ADAM-TS 12) (ADAM-TS12) (ADAMTS-12) (EC 3.4.24.-)Adamts12Q811B32
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAM-TS 5) (ADAM-TS5) (ADAMTS-5) (EC 3.4.24.-) (ADMP-2) (Aggrecanase-2) (Implantin)Adamts5Q9R0012
A-kinase anchor protein 9 (AKAP-9) (Protein kinase A-anchoring protein 9) (PRKA9)Akap9 Kiaa0803Q70FJ12
Acetyl-CoA acetyltransferase, cytosolic (MCG16689, isoform CRA_a)Acat2 mCG_16689G3XA252
Acetyl-Coenzyme A acetyltransferase 3 (Putative uncharacterized protein)Acat3Q80X812
Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)Acss2 Acas2 Acecs1Q9QXG42
Acidic leucine-rich nuclear phosphoprotein 32 family member A (Fragment)Anp32aF6UFG62
Acidic leucine-rich nuclear phosphoprotein 32 family member E (Fragment)Anp32eE9Q5H22
Acp1 protein (Low molecular weight phosphotyrosine protein phosphatase) (MCG7808, isoform CRA_c) (Putative uncharacterized protein)Acp1 mCG_7808Q561M12
Actin filament-associated protein 1 (110 kDa actin filament-associated protein) (AFAP-110)Afap1 Kiaa3018Q80YS62
Actin filament-associated protein 1 (Fragment)Afap1E9Q8X92
Actin-related protein 2/3 complex subunit 5-like proteinArpc5lA0A0R3P9C92
Active regulator of SIRT1 (40S ribosomal protein S19-binding protein 1) (RPS19-binding protein 1) (S19BP)Rps19bp1 ArosQ8C6B92
Acyl-CoA dehydrogenase family member 11Acad11D3YTQ52
Acyl-CoA desaturase 2 (EC 1.14.19.1) (Delta(9)-desaturase 2) (Delta-9 desaturase 2) (Fatty acid desaturase 2) (Stearoyl-CoA desaturase 2)Scd2P130112
Acyl-CoA synthetase family member 2, mitochondrial (EC 6.2.1.-)Acsf2Q8VCW82
Acyl-CoA-binding proteinDbiD3Z5632
Acyl-CoA-binding protein (Diazepam binding inhibitor, splice form 1b) (MCG17804, isoform CRA_b)Dbi mCG_17804Q4VWZ52
Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Thioesterase superfamily member 2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed]Acot13 Them2Q9CQR42
Acyl-protein thioesterase 1Lypla1D3Z1112
Acylphosphatase-1 (EC 3.6.1.7) (Acylphosphatase, organ-common type isozyme) (Acylphosphate phosphohydrolase 1)Acyp1 AcypeP563762
Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1)Necap1Q9CR952
Adenomatosis polyposis coli 2 (Adenomatous polyposis coli protein 2)Apc2 mCG_13417G5E8322
Adenosylhomocysteinase (EC 3.3.1.1)Ahcyl2H3BKT52
Adenylate cyclase type 3 (EC 4.6.1.1) (ATP pyrophosphate-lyase 3) (Adenylate cyclase type III) (AC-III) (Adenylate cyclase, olfactive type) (Adenylyl cyclase 3) (AC3)Adcy3Q8VHH72
Adenylate cyclase type 6Adcy6F8VQ522
Adenylate cyclase type 9Adcy9E9Q7062
Adenylate kinase 4, mitochondrial (AK 4) (EC 2.7.4.10) (EC 2.7.4.6) (Adenylate kinase 3-like) (Adenylate kinase isoenzyme 4) (GTP:AMP phosphotransferase AK4)Ak4 Ak-4 Ak3b Ak3l1Q9WUR92
Adenylate kinase 4, mitochondrial (Fragment)Ak4A2ARF62
Adenylyl cyclase-associated protein 2 (CAP 2)Cap2Q9CYT62
Adhesion G protein-coupled receptor A2Adgra2J3QMG72
Adhesion G protein-coupled receptor E5Adgre5 Cd97E9QJS72
Adhesion G protein-coupled receptor E5Adgre5A0A0D9SEG82
Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2)Adgrl1 Kiaa0821 Lec2 Lphn1Q80TR12
Adhesion G protein-coupled receptor L2 (Calcium-independent alpha-latrotoxin receptor 2) (CIRL-2) (Latrophilin-2)Adgrl2 Kiaa0786 Lphn2E9Q6C72
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