EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Adhesion G protein-coupled receptor L3Adgrl3D3Z5M62
Adhesion G-protein coupled receptor G6 (Developmentally regulated G-protein-coupled receptor) (G-protein coupled receptor 126) [Cleaved into: ADGRG6 N-terminal fragment (ADGRG6-NTF); ADGRG6 C-terminal fragment (ADGRG6-CTF)]Adgrg6 Dreg Gm222 Gpr126Q6F3F92
Adipocyte-related X-chromosome expressed sequence 1Arxes1C0HK792
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 (EC 3.2.2.6) (ADP-ribosyl cyclase 2) (Antigen BP3) (BP-3 alloantigen) (Bone marrow stromal antigen 1) (BST-1) (Cyclic ADP-ribose hydrolase 2) (cADPr hydrolase 2) (Leukocyte antigen 65) (Ly-65) (CD antigen CD157)Bst1 Bp-3 Bp3 Ly65Q642772
ADP-ribosylation factor-like protein 1 (Fragment)Arl1F8WIB12
ADP-ribosylation factor-like protein 6 (Fragment)Arl6D3Z0672
AF4/FMR2 family member 4Aff4 Alf4Q9ESC82
Afadin (Fragment)AfdnD3YUD22
AFG3-like protein 1 (EC 3.4.24.-)Afg3l1Q920A72
Aladin (Adracalin)AaasP587422
Aldo-keto reductase a (Aldo-keto reductase family 1, member C12) (MCG114465, isoform CRA_a) (Putative uncharacterized protein)Akr1c12 Akra mCG_114465Q9JLI02
Aldo-keto reductase family 1, member E1 (Putative uncharacterized protein)Akr1e1Q8CEB62
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.145) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa) (GlcNAc-T IVa) (GnT-IVa) (N-acetylglucosaminyltransferase IVa) (UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa) [Cleaved into: Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form]Mgat4aQ812G02
Alpha-1,4 glucan phosphorylase (EC 2.4.1.1)PyglQ3UEJ62
Alpha-1-syntrophinSnta1A2AKD72
Alpha-aminoadipic semialdehyde dehydrogenase (Alpha-AASA dehydrogenase) (EC 1.2.1.31) (Aldehyde dehydrogenase family 7 member A1) (EC 1.2.1.3) (Antiquitin-1) (Betaine aldehyde dehydrogenase) (EC 1.2.1.8) (Delta1-piperideine-6-carboxylate dehydrogenase) (P6c dehydrogenase)Aldh7a1 Ald7a1Q9DBF12
Alpha-galactosidase A (Putative uncharacterized protein)GlaQ8BGZ62
Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase)Amacr Macr1O091742
Alpha-tectorinTectaO085232
Amine oxidase (EC 1.4.3.-) (Fragment)Aoc3A2A4I82
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (JTV1 protein)Aimp2 Jtv1Q8R3V22
Aminoacylase-1 (ACY-1) (EC 3.5.1.14) (N-acyl-L-amino-acid amidohydrolase)Acy1Q99JW22
AMP deaminase 3 (EC 3.5.4.6) (AMP deaminase H-type) (AMP deaminase isoform E) (Heart-type AMPD)Ampd3O087392
Anaphase-promoting complex subunit 7Anapc7D3YU582
Ancient ubiquitous protein 1 (Putative uncharacterized protein)Aup1Q3U3K92
AngiomotinAmot Kiaa1071Q8VHG22
Angiopoietin-1 (ANG-1)Angpt1 AgptO085382
Ankyrin repeat domain-containing protein 40Ankrd40Q5SUE82
Ankyrin repeat domain-containing protein 42Ankrd42Q3V0962
Ankyrin-3 (ANK-3) (Ankyrin-G)Ank3G5E8K52
AnnexinAnxa2 mCG_5731Q542G92
AnnexinAnxa6Q99JX62
AnnexinAnxa1Q3US432
Apolipoprotein B receptor (Apolipoprotein B-100 receptor) (Apolipoprotein B48 receptor) (apoB-48R)Apobr Apob48rQ8VBT62
Apolipoprotein C-II (Apo-CII) (ApoC-II) (Apolipoprotein C2)Apoc2Q050202
Apoptosis, caspase activation inhibitor, isoform CRA_c (Cell death regulator Aven)Aven mCG_20779A2AGL52
Apoptosis-inducing factor 1, mitochondrialAifm1B1AU252
Apoptosis-inducing factor 2 (EC 1.-.-.-) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (Apoptosis-inducing factor-like mitochondrion-associated inducer of death)Aifm2 AmidQ8BUE42
Apoptosis-stimulating of p53 protein 2 (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)Tp53bp2 Aspp2 Trp53bp2Q8CG792
Apoptotic protease-activating factor 1 (APAF-1)Apaf1 mCG_10338G3XA092
Arachidonate 5-lipoxygenase (5-LO) (5-lipoxygenase) (EC 1.13.11.34)Alox5P489992
ARF GTPase-activating protein GIT2 (G protein-coupled receptor kinase-interactor 2)Git2Q80XR82
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Agap1E9Q3K32
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3Agap3F8VQE92
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1Asap1H3BKD42
Arginase-2, mitochondrial (EC 3.5.3.1) (Arginase II) (Kidney-type arginase) (Non-hepatic arginase) (Type II arginase)Arg2O086912
Arginyl-tRNA--protein transferase 1 (Arginyltransferase 1) (R-transferase 1) (EC 2.3.2.8) (Arginine-tRNA--protein transferase 1)Ate1J3QNU12
Armadillo repeat containing 8, isoform CRA_b (Armadillo repeat-containing protein 8)Armc8 mCG_18099G3X9202
Armadillo repeat-containing protein 10Armc10Q9D0L72
Armadillo repeat-containing protein 4Armc4B2RY502
Armet protein (Mesencephalic astrocyte-derived neurotrophic factor)Manf ArmetQ80ZP82
Arpin (Arp2/3 inhibition protein)ArpinQ9D0A32
Arylsulfatase A (ASA) (EC 3.1.6.8) (Cerebroside-sulfatase)Arsa As2P504282
Arylsulfatase BArsbA0A0R4J1382
Aspartyl aminopeptidase (Putative uncharacterized protein)DnpepQ3TVK32
Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase)Asph BahQ8BSY02
AT-rich interactive domain-containing protein 1AArid1aE9QAQ72
Ataxin 7-like 1 (Ataxin-7-like protein 1)Atxn7l1B2RW072
Atlastin-2Atl2E9QND82
Atlastin-3Atl3E9PYT32
ATP synthase mitochondrial F1 complex assembly factor 2Atpaf2Q91YY42
ATP synthase protein 8mt-Atp8 ATP8 Atp8 ATPase 8 ATPase8 mt-Atp6Q7JCZ02
ATP synthase subunit gammaAtp5c1A2AKU92
ATP-binding cassette sub-family A member 3Abca3Q8R4202
ATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog)Abcg1 Abc8 Wht1Q643432
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (Caseinolytic peptidase X (E.coli))ClpxQ6P8N82
ATP-dependent RNA helicase DDX4 (EC 3.6.4.13) (DEAD box protein 4) (Mvh) (Vasa homolog)Ddx4 Mvh VasaQ614962
ATP-dependent RNA helicase DDX51 (EC 3.6.4.13) (DEAD box protein 51)Ddx51Q6P9R12
ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (DEAD box protein 54)Ddx54Q8K4L02
ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (YME1-like protein 1)Yme1l1O889672
Atp2b1 protein (Fragment)Atp2b1Q05CJ52
ATPase family AAA domain-containing protein 3 (AAA-ATPase TOB3)Atad3 Atad3a Kiaa1273Q925I12
Atrial natriuretic peptide receptor 3 (Atrial natriuretic peptide clearance receptor) (Atrial natriuretic peptide receptor type C) (ANP-C) (ANPR-C) (NPR-C) (EF-2)Npr3P701802
Autophagy protein 5 (APG5-like)Atg5 Apg5lQ99J832
Autophagy-related protein 2 homolog BAtg2bQ80XK62
Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin) (TIAP)Birc5 Api4 Iap4O702012
Band 4.1-like protein 4B (Protein EHM2)Epb41l4b Ehm2 Epb4.1l4b Lulu2Q9JMC82
Basal cell adhesion molecule (Fragment)BcamD3YTK72
BC051142 protein (CDNA sequence BC051142) (Testis specific basic protein)BC051142 Tesb RP23-24A13.2-001Q80XD02
Bcl-2-like protein 13 (Bcl2-L-13) (Bcl-rambo) (Protein Mil1)Bcl2l13 Mil1P590172
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe (EC 2.4.1.222) (O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase)LfngO090102
Beta-galactoside alpha-2,6-sialyltransferase 1 (Alpha 2,6-ST 1) (EC 2.4.99.1) (CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1) (ST6Gal I) (ST6GalI) (Sialyltransferase 1)St6gal1 Siat1Q646852
Beta-globinHbbt1A8DUN22
Beta-mannosidaseManbaA0A0R4J0922
Beta-nerve growth factor (Nerve growth factor) (Nerve growth factor, beta, isoform CRA_b) (Putative uncharacterized protein)Ngf NGF Ngfb mCG_5471Q6LDU82
BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]BidP704442
Bifunctional polynucleotide phosphatase/kinase (Polynucleotide kinase 3'-phosphatase, isoform CRA_b)Pnkp mCG_23134G5E8N72
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] (EC 3.6.1.17) (Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase) (Ap4A hydrolase) (Ap4Aase) (Diadenosine tetraphosphatase) (Nucleoside diphosphate-linked moiety X motif 2) (Nudix motif 2)Nudt2 Apah1P563802
Box C/D snoRNA protein 1 (Zinc finger HIT domain-containing protein 6)Znhit6 Bcd1Q3UFB22
Brain protein I3Bri3P286622
Brain protein I3 (MCG17951, isoform CRA_b) (Putative uncharacterized protein)Bri3 mCG_17951Q8C7X82
Branched-chain-amino-acid aminotransferase (EC 2.6.1.42)Bcat1Q8CBC82
BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1)Brat1 Baat1Q8C3R12
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (p130cas)Bcar1 Cas CrkasQ611402
Breast carcinoma-amplified sequence 1 homolog (Novel amplified in breast cancer 1 homolog)Bcas1 Nabc1Q80YN32
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 (ARFGEF family member 3)Arfgef3 Big3 D10Bwg1379e Kiaa1244Q3UGY82
Brevican core proteinBcanQ613612
Bromodomain-containing protein 2 (Female sterile homeotic-related protein 1) (Fsrg-1) (Protein RING3)Brd2 Fsrg1 Kiaa4005 Ring3Q7JJ132
BTB/POZ domain-containing protein KCTD2 (Potassium channel tetramerisation domain containing 2)Kctd2Q4VBE72
BUD13 homologBud13Q8R1492
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