EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191)Ccr1 Cmkbr1P516752
C-C motif chemokine 4 (Immune activation protein 2) (ACT-2) (ACT2) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4)Ccl4 Mip1b Scya4P140972
C-Myc-binding protein (Associate of Myc 1) (AMY-1)Mycbp Amy1Q9EQS32
C-X-C chemokine receptor type 2 (CXC-R2) (CXCR-2) (GRO/MGSA receptor) (High affinity interleukin-8 receptor B) (IL-8R B) (CD antigen CD182)Cxcr2 Cmkar2 Gpcr16 Il8rbP353432
C-X-C motif chemokineCxcl10D3YW232
C-X-C motif chemokine 5 (Cytokine LIX) (Small-inducible cytokine B5) [Cleaved into: GCP-2(1-78); GCP-2(9-78)]Cxcl5 Scyb5P502282
C3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R) (Complement component 3a receptor 1)C3ar1 C3r1O090472
C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)C5ar1 C5ar C5r1Q3TZ862
Cadherin-2Cdh2D3YYT02
Cadherin-5 (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)Cdh5P552842
Calcium homeostasis modulator protein 2Calhm2D3Z2E82
Calcium release-activated calcium channel protein 1 (Protein orai-1) (Transmembrane protein 142A)Orai1 Cracm1 Tmem142aQ8BWG92
Calcium-binding mitochondrial carrier protein SCaMC-2 (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25)Slc25a25 Kiaa1896 Scamc2A2ASZ82
Calcium-transporting ATPase (EC 3.6.3.8)Atp2b3Q8C0482
Calcium-transporting ATPase (EC 3.6.3.8)Atp2b3A2ALL92
Calcium-transporting ATPase (EC 3.6.3.8)Atp2b3Q0VF542
Calcium/calmodulin-dependent protein kinase II, beta, isoform CRA_b (Calcium/calmodulin-dependent protein kinase type II subunit beta)Camk2b mCG_122182Q5SVJ02
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)Camk2aP117982
Calcium/calmodulin-dependent protein kinase type II subunit beta (CaM kinase II subunit beta) (CaMK-II subunit beta) (EC 2.7.11.17)Camk2b Camk2dP286522
Calcium/calmodulin-dependent protein kinase type II subunit deltaCamk2dE9Q1T12
Caldesmon 1Cald1D3Z6I72
Caldesmon 1Cald1E9QA162
Calmodulin-binding transcription activator 2Camta2 Kiaa0909Q80Y502
Calpain small subunit 1 (Calpain, small subunit 1)Capns1 mCG_21569D3YW482
Calpain small subunit 1 (Calpain, small subunit 1)Capns1 mCG_21569A0A0R4IZW82
Calpain-6Capn6 Capa6O356462
cAMP-regulated phosphoprotein 19 (ARPP-19)Arpp19P562122
CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2)Clip2 Cyln2 Kiaa0291Q9Z0H82
CapZ-interacting protein (Protein kinase substrate CapZIP)Rcsd1 CapzipQ3UZA12
Carabin (TBC1 domain family member 10C)Tbc1d10cQ8C9V12
Carbohydrate sulfotransferase 12 (EC 2.8.2.5) (Chondroitin 4-O-sulfotransferase 2) (Chondroitin 4-sulfotransferase 2) (C4ST-2) (C4ST2)Chst12Q99LL32
Carbonic anhydrase 13 (EC 4.2.1.1) (Carbonate dehydratase XIII) (Carbonic anhydrase XIII) (CA-XIII)Ca13 Car13Q9D6N12
Carnosine N-methyltransferase (EC 2.1.1.22)Carnmt1Q80UY12
Casein kinase I isoform alphaCsnk1a1E9Q2U62
Casein kinase I isoform gamma-1 (Csnk1g1 protein)Csnk1g1Q6P2B22
Caseinolytic peptidase B protein homolog (EC 3.6.1.3) (Suppressor of potassium transport defect 3)Clpb Skd3Q606492
CASP8-associated protein 2 (FLICE-associated huge protein)Casp8ap2 FlashQ9WUF32
Caspase recruitment domain family, member 6Card6E9PWH22
Caspase recruitment domain-containing protein 9Card9A2AIV82
Caspase-7 (CASP-7) (EC 3.4.22.60) (Apoptotic protease Mch-3) (Cysteine protease LICE2) [Cleaved into: Caspase-7 subunit p20; Caspase-7 subunit p11]Casp7 Lice2 Mch3P978642
Catechol O-methyltransferase domain-containing protein 1Comtd1H3BJ372
Catenin delta-1Ctnnd1E9Q8Z82
Catenin delta-1Ctnnd1E9Q8Z42
Cathepsin K (EC 3.4.22.38)CtskP550972
CCA tRNA nucleotidyltransferase 1, mitochondrial (EC 2.7.7.72) (mitochondrial tRNA nucleotidyl transferase, CCA-adding) (mt CCA-adding enzyme) (mt tRNA CCA-diphosphorylase) (mt tRNA CCA-pyrophosphorylase) (mt tRNA adenylyltransferase)Trnt1Q8K1J62
Ccnb1 protein (G2/mitotic-specific cyclin-B1)Ccnb1Q68EM32
CCR4-NOT transcription complex subunit 2 (CCR4-associated factor 2)Cnot2Q8C5L32
CCR4-NOT transcription complex subunit 8 (EC 3.1.13.4) (CCR4-associated factor 8)Cnot8Q9D8X52
CD48 antigen (BCM1 surface antigen) (BLAST-1) (HM48-1) (MRC OX-45 surface antigen) (SLAM family member 2) (SLAMF2) (Signaling lymphocytic activation molecule 2) (sgp-60) (CD antigen CD48)Cd48 Bcm-1P181812
CD99 antigen-like protein 2 (MIC2-like protein 1) (CD antigen CD99)Cd99l2 Mic2l1Q8BIF02
CDKN2A-interacting protein (Collaborator of ARF)Cdkn2aip CarfQ8BI722
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (EC 2.7.8.5) (Phosphatidylglycerophosphate synthase 1) (PGP synthase 1) (Silencer-associated factor)Pgs1 SafQ8BHF72
Cell adhesion molecule 1 (Cell adhesion molecule 1 transcript variant 8abc)Cadm1E9PYN12
Cell death regulator AvenAvenQ9D9K32
Cell migration-inducing and hyaluronan-binding protein (EC 3.2.1.35) (Protein 12H19.01.T7)Cemip Kiaa1199Q8BI062
Cell surface glycoprotein CD200 receptor 1 (CD200 cell surface glycoprotein receptor) (Cell surface glycoprotein OX2 receptor 1)Cd200r1 Mox2r Ox2rQ9ES572
Cellular nucleic acid binding protein, isoform CRA_a (Putative uncharacterized protein)Cnbp Cnbp1 mCG_130858D3YYF62
Cellular repressor of E1A-stimulated genes 1, isoform CRA_a (Protein CREG1)Creg1 mCG_3602K4DI632
Cellular retinoic acid-binding protein 2 (Cellular retinoic acid-binding protein II) (CRABP-II)Crabp2P229352
Centriolin (Centrosomal protein 1) (Centrosomal protein of 110 kDa) (Cep110)Cntrl Cep1 Cep110A2AL362
Centrosomal protein of 170 kDaCep170H7BX262
Centrosomal protein of 170 kDa protein B (Centrosomal protein 170B) (Cep170B)Cep170b Kiaa0284Q80U492
Centrosomal protein of 290 kDaCep290E9Q9M02
Ceramide synthase 2 (Fragment)Cers2 Lass2D3Z4M22
Cerebellin-1 (Brain protein D3) (Precerebellin) [Cleaved into: Cerebellin (CER); [des-Ser1]-cerebellin (des-Ser1-cerebellin)]Cbln1Q9R1712
CGG triplet repeat-binding protein 1 (CGG-binding protein 1) (20 kDa CGG-binding protein) (p20-CGGBP DNA-binding protein)Cggbp1Q8BHG92
cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE)Pde2aQ922S42
Charged multivesicular body protein 6 (Fragment)Chmp6B1AZ422
Charged multivesicular body protein 7 (Chromatin-modifying protein 7)Chmp7Q8R1T12
Chitotriosidase-1 (EC 3.2.1.14) (Chitinase-1)Chit1Q9D7Q12
Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A)Pcyt1a Ctpct Pcyt1P495862
Chondroitin sulfate proteoglycan 5 (Acidic leucine-rich EGF-like domain-containing brain protein) (Neuroglycan C)Cspg5 Caleb NgcQ71M362
Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.12)Chd1lQ9CXF72
Chromodomain-helicase-DNA-binding protein 4Chd4E9QAS42
Chromodomain-helicase-DNA-binding protein 4Chd4E9QAS52
Chromosome transmission fidelity protein 8 homolog isoform 2Chtf8 DerpcP0CG142
Chymase (EC 3.4.21.39) (Alpha-chymase) (Mast cell chymase 1) (Mast cell protease 5) (mMCP-5) (Mast cell protease I)Cma1 Mcpt5P218442
Cilia- and flagella-associated protein 20 (Gene trap locus 3 protein)Cfap20 Gtl3Q8BTU12
Cilia- and flagella-associated protein 36 (Coiled-coil domain-containing protein 104)Cfap36 Ccdc104Q8C6E02
Clathrin interactor 1 (Putative uncharacterized protein)Clint1 AI642036Q5SUH72
Claudin domain-containing protein 1 (Fragment)Cldnd1E0CY632
Claudin-6 (Skullin)Cldn6Q9Z2622
CLIP-associating protein 2Clasp2F7DCH52
Clustered mitochondria protein homologCluhZ4YLI82
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.99.-) (Alpha-2,8-sialyltransferase 8D) (Polysialyltransferase-1) (Sialyltransferase 8D) (SIAT8-D) (Sialyltransferase St8Sia IV) (ST8SiaIV)St8sia4 Pst Siat8dQ646922
CMP-sialic acid transporter (CMP-SA-Tr) (CMP-Sia-Tr) (Solute carrier family 35 member A1)Slc35a1Q614202
Coagulation factor VII (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Cleaved into: Factor VII light chain; Factor VII heavy chain]F7 Cf7P703752
Coatomer subunit alphaCopaQ8BTF02
Cochlin (COCH-5B2)CochQ625072
Codanin-1Cdan1Q8CC122
Cofilin 1, non-muscle (Putative uncharacterized protein)Cfl1 mCG_11768Q544Y72
Coiled-coil domain-containing protein 115 (Coiled-coil protein 1) (Ccp1)Ccdc115Q8VE992
Coiled-coil domain-containing protein 167 (Fragment)Ccdc167 1110021J02RikF6WM752
Coiled-coil domain-containing protein 182Ccdc182Q9D9C62
Coiled-coil domain-containing protein 50 (Fragment)Ccdc50F6UK662
Coiled-coil domain-containing protein 91 (GGA-binding partner)Ccdc91 GgabpQ9D8L52
Cold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)Cirbp CirpP608242
Collagen alpha-1(XIX) chain (Collagen alpha-1(Y) chain)Col19a1Q0VF582
Collagen alpha-1(XVI) chainCol16a1Q8BLX72
Collagen alpha-2(XI) chainCol11a2Q647392
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