EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Collagen alpha-3(IV) chain [Cleaved into: Tumstatin]Col4a3Q9QZS02
Collagen and calcium-binding EGF domain-containing protein 1 (Full of fluid protein homolog)Ccbe1 Kiaa1983Q3MI992
Collagen type IV alpha-3-binding protein (Ceramide transfer protein) (Goodpasture antigen-binding protein) (GPBP) (START domain-containing protein 11) (StARD11) (StAR-related lipid transfer protein 11)Col4a3bp Stard11Q9EQG92
Collagen, type VI, alpha 3Col6a3E9PWQ32
Collagenase 3 (EC 3.4.24.-) (Matrix metalloproteinase-13) (MMP-13)Mmp13P334352
Collectin-11 (Collectin kidney protein 1) (CL-K1)Colec11Q3SXB82
COMM domain containing 1, isoform CRA_b (COMM domain-containing protein 1) (U2/MU protein)Commd1 U2/MU mCG_52266Q8VI862
COMM domain-containing protein 1 (Protein Murr1)Commd1 Murr1Q8K4M52
Complement C1q tumor necrosis factor-related protein 1 (Putative secreted protein ZSIG37)C1qtnf1 Zsig37Q9QXP72
Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-)C1rl C1rlpQ3UZ092
Complement component 1 Q subcomponent-binding protein, mitochondrial (GC1q-R protein) (Glycoprotein gC1qBP) (C1qBP)C1qbp Gc1qbpO356582
Complement component C1q receptor (C1q/MBL/SPA receptor) (C1qR(p)) (C1qRp) (Cell surface antigen AA4) (Complement component 1 q subcomponent receptor 1) (Lymphocyte antigen 68) (Ly-68) (CD antigen CD93)Cd93 Aa4 C1qr1 C1qrp Ly68O891032
Condensin complex subunit 1Ncapd2A0A0R4J0H72
Conserved oligomeric Golgi complex subunit 3Cog3E9QL652
COP9 signalosome complex subunit 1 (MCG2137, isoform CRA_a)Gps1 mCG_2137B1ATU42
COP9 signalosome complex subunit 2Cops2A2AQE42
CorneodesmosinCdsnQ7TPC12
Cornifin-A (Small proline-rich protein 1A) (SPR1 A) (SPR1A)Sprr1aQ622662
Cornifin-B (Small proline-rich protein 1B) (SPR1 B) (SPR1B)Sprr1bQ622672
Cox7a2l proteinCox7a2l Gm6969Q99KD62
Crystallin, zeta (Quinone reductase)-like 1, isoform CRA_h (Quinone oxidoreductase-like protein 1)Cryzl1 mCG_118985D3Z6I42
CST complex subunit STN1 (Alpha-accessory factor of 44 kDa) (AAF-44) (AAF44) (Oligonucleotide/oligosaccharide-binding fold-containing protein 1) (Suppressor of cdc thirteen homolog)Stn1 Obfc1Q8K2X32
CTTNBP2 N-terminal-like proteinCttnbp2nl Kiaa1433Q99LJ02
Cullin 5 (Cullin-5)Cul5 mCG_5637G3X9142
Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (C/EBP-related ATF) (C/ATF) (Tax-responsive enhancer element-binding protein 67 homolog) (TaxREB67 homolog)Atf4Q065072
Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1)Cdk14 Kiaa0834 Pftk1O354952
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (P39 Mo15) (CDK-activating kinase) (CR4 protein kinase) (CRK4) (Cell division protein kinase 7) (Protein-tyrosine kinase MPK-7) (TFIIH basal transcription factor complex kinase subunit)Cdk7 Cak Cdkn7 Crk4 Mo15 Mpk-7Q031472
Cyclin-dependent kinases regulatory subunit 2 (CKS-2)Cks2P563902
Cyclin-L1 (Cyclin-L) (Cyclin Ania-6a)Ccnl1 Ania6a Ccn1Q52KE72
CystatinCst6 mCG_11738Q9D1B12
Cysteine desulfurase, mitochondrial (m-Nfs1) (EC 2.8.1.7)Nfs1 NifsQ9Z1J32
Cysteine protease ATG4A (EC 3.4.22.-) (AUT-like 2 cysteine endopeptidase) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (Autophagy-related protein 4 homolog A)Atg4a Apg4a Autl2Q8C9S82
Cysteine protease ATG4B (EC 3.4.22.-) (AUT-like 1 cysteine endopeptidase) (Autophagin-1) (Autophagy-related cysteine endopeptidase 1) (Autophagy-related protein 4 homolog B)Atg4b Apg4b Autl1 Kiaa0943Q8BGE62
Cysteine sulfinic acid decarboxylase (EC 4.1.1.29) (Cysteine-sulfinate decarboxylase) (Sulfinoalanine decarboxylase)CsadQ9DBE02
Cysteine-rich motor neuron 1 protein (CRIM-1)Crim1Q9JLL02
Cysteine-rich protein 1 (CRP-1) (Cysteine-rich intestinal protein) (CRIP)Crip1 CripP632542
Cysteine-rich with EGF-like domain protein 2Creld2Q9CYA02
Cytidine monophospho-N-acetylneuraminic acid synthetase (N-acylneuraminate cytidylyltransferase)Cmas mCG_7111A0A0R4J0B42
Cytochrome c oxidase subunit 2mt-Co2 Co2 COII COX2 Cox2 COXIIQ7JCZ12
Cytochrome c oxidase subunit 5B, mitochondrial (Cytochrome c oxidase, subunit Vb) (MCG17741, isoform CRA_d) (MCG23026) (Putative uncharacterized protein)Cox5b Gm11273 mCG_17741 mCG_23026Q9D8812
Cytochrome c oxidase subunit 5B, mitochondrial (Fragment)Cox5bF7C1062
Cytochrome c oxidase subunit 7C, mitochondrial (Cytochrome c oxidase polypeptide VIIc)Cox7c Cox7c1P176652
Cytohesin-4 (PH, SEC7 and coiled-coil domain-containing protein 4)Cyth4 Pscd4Q80YW02
Cytokine receptor common subunit beta (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)Csf2rb Aic2b Csf2rb1 Il3rb1P269552
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)Il2rgP349022
Cytoplasmic dynein 1 intermediate chain 2Dync1i2A2BFF92
Cytoskeletal proteinUtrn utrophinO086142
Cytoskeleton-associated protein 2Ckap2Q3V1H12
Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2)Nubp2Q9R0612
Cytospin-A (SPECC1-like protein) (Sperm antigen with calponin homology and coiled-coil domains 1-like)Specc1l Cytsa Kiaa0376Q2KN982
DBIRD complex subunit ZNF326 (Zinc finger protein 326) (Zinc finger protein interacting with mRNPs) (Zinc finger protein-associated with nuclear matrix of 75 kDa)Znf326 Zan75 Zfp326 ZirdO882912
DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1)Dcaf13 Gm83 Wdsof1Q6PAC32
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b (MCG133615, isoform CRA_a) (Putative uncharacterized protein)Ddx19b mCG_133615Q8R3C72
Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.-) (Nitrilase homolog 1)Nit1Q8VDK12
Death-associated protein kinase 3 (DAP kinase 3) (EC 2.7.11.1) (DAP-like kinase) (Dlk) (MYPT1 kinase) (ZIP-kinase)Dapk3 ZipkO547842
Death-inducer obliterator 1 (DIO-1) (Death-associated transcription factor 1) (DATF-1)Dido1 Datf1 Dio1Q8C9B92
Dehydrogenase/reductase SDR family member 11 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 24C member 1)Dhrs11 Sdr24c1Q3U0B32
Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4)Dhrs7 Retsdr4Q9CXR12
Dehydrogenase/reductase SDR family member 7BDhrs7bZ4YKT62
Deleted in autism protein 1 homolog (Golgi Protein of 49 kDa) (GoPro49) (Hypoxia and AKT-induced stem cell factor) (HASF)0Q3USZ82
Delta-1-pyrroline-5-carboxylate synthase [Includes: Glutamate 5-kinase (GK) (EC 2.7.2.11) (Gamma-glutamyl kinase); Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase)]Aldh18a1Q3TWN82
DENN domain-containing protein 2DDennd2dQ91VV42
DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1)Dennd5a Rab6ip1Q6PAL82
Desmocollin-2 (Epithelial type 2 desmocollin)Dsc2 Dsc3P552922
Desmoglein-1-alpha (Desmoglein-1) (Dsg1-alpha) (DG1) (DGI) (Desmosomal glycoprotein I)Dsg1a Dsg1Q614952
Desmoglein-3 (130 kDa pemphigus vulgaris antigen homolog)Dsg3O359022
DesmoplakinDspE9PZW02
Deubiquitinating protein VCIP135Vcpip1A0A0R4J0M92
Diacylglycerol O-acyltransferase 1 (EC 2.3.1.20) (Acyl-CoA retinol O-fatty-acyltransferase) (ARAT) (Retinol O-fatty-acyltransferase) (EC 2.3.1.76) (Diglyceride acyltransferase)Dgat1 DgatQ9Z2A72
Dicarbonyl L-xylulose reductase, isoform CRA_a (L-xylulose reductase)Dcxr mCG_2129A2AC162
DiGeorge syndrome critical region gene 2, isoform CRA_d (Integral membrane protein DGCR2/IDD) (Putative uncharacterized protein)Dgcr2 mCG_131834Q8C2R42
Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1)Tfb1mQ8JZM02
Dipeptidyl peptidase 1 (Fragment)CtscD3Z2202
DIS3-like exonuclease 2 (EC 3.1.13.-)Dis3l2Q8CI752
Disabled homolog 2Dab2E9PX842
Disabled homolog 2 (Putative uncharacterized protein)Dab2Q3TRE62
Disks large homolog 1Dlg1H7BWY42
DNA ligase (EC 6.5.1.1)Lig1Q3U4X82
DNA ligase (EC 6.5.1.1)Lig3 mCG_8187Q80ZH72
DNA polymerase alpha subunit B (DNA polymerase alpha 70 kDa subunit)Pola2P336112
DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-)PolbQ8K4092
DNA polymerase delta subunit 2 (DNA polymerase delta subunit p50)Pold2O356542
DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4)Ercc4Q9QZD42
DNA replication ATP-dependent helicase/nuclease DNA2 (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]Dna2 Dna2l Kiaa0083Q6ZQJ52
DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D)Polr3d Bn51tQ91WD12
DNA-directed RNA polymerase subunit (EC 2.7.7.6)Polr3aB2RXC62
DNA-directed RNA polymerases I and III subunit RPAC1 (Fragment)Polr1cG3UXX52
DNA/RNA-binding protein KIN17 (Binding to curved DNA) (KIN, antigenic determinant of recA protein)Kin Btcd Kin17Q8K3392
DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (mTid-1) (Tumorous imaginal discs protein Tid56 homolog)Dnaja3 Tid1Q99M872
DnaJ homolog subfamily A member 4 (MmDjA4)Dnaja4Q9JMC32
DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (mDj7)Dnajb9Q9QYI62
DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1)Dnajc1 Dnajl1 Mtj1Q617122
DnaJ homolog subfamily C member 11Dnajc11Q5U4582
DnaJ homolog subfamily C member 2Dnajc2E9Q9H22
Docking protein 3 (Downstream of tyrosine kinase 3) (p62(dok)-like protein) (DOK-L)Dok3 DoklQ9QZK72
Docking protein 5 (Downstream of tyrosine kinase 5)Dok5Q91ZM92
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1)Stt3a Itm1P469782
Dolichyl-phosphate beta-glucosyltransferaseAlg5D6RCG22
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (RNA adenosine deaminase 1)AdarQ99MU32
Dual serine/threonine and tyrosine protein kinase (EC 2.7.12.1) (Dusty protein kinase) (Dusty PK) (Receptor-interacting serine/threonine-protein kinase 5)Dstyk Ripk5Q6XUX12
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