EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Ubiquitin-conjugating enzyme E2 variant 2Ube2v2B2KF552
Ubiquitin-fold modifier 1Ufm1P619612
Ubiquitin-fold modifier conjugating enzyme 1, isoform CRA_c (Ubiquitin-fold modifier-conjugating enzyme 1)Ufc1 mCG_8647M0QWS42
Ubiquitin-like modifier-activating enzyme ATG7Atg7S4R2D52
UBX domain containing 2, isoform CRA_a (UBX domain-containing protein 4)Ubxn4 Ubxd2 mCG_20043A0A0R4J0782
UMP-CMP kinase (EC 2.7.4.14) (Deoxycytidylate kinase) (CK) (dCMP kinase) (Nucleoside-diphosphate kinase) (EC 2.7.4.6) (Uridine monophosphate/cytidine monophosphate kinase) (UMP/CMP kinase) (UMP/CMPK)Cmpk1 CMPK CMPK1 mCG_16168A0A0R4J0932
Uncharacterized proteinGm15127L7N2362
Uncharacterized proteinGm2663 1810009J06RikF6R7E82
Uncharacterized proteinGm7075D3Z4972
Uncharacterized proteinGm10073E9Q3T02
Uncharacterized protein C17orf62 homolog0Q3TYS22
Uncharacterized protein C18orf8 homolog (Colon cancer-associated protein Mic1) (Mic-1)Mic1Q8VC422
Uncharacterized protein C19orf43 homolog0Q9D7352
Uncharacterized protein C5orf52 homolog0Q9CR342
Uncharacterized protein C6orf47 homologD17h6s53eQ9Z1R42
Uncharacterized protein KIAA0930 homolog0Q3UE312
Unconventional myosin-IXbMyo9bE9QKV62
Unconventional myosin-VIMyo6E9Q3L12
Unconventional myosin-VI (Unconventional myosin-6)Myo6 SvQ643312
Unconventional myosin-XV (Unconventional myosin-15)Myo15a Myo15Q9QZZ42
Unconventional myosin-XVIIIaMyo18aE9QAX22
Unconventional prefoldin RPB5 interactor (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein)Uri1 Nnx3 Ppp1r19 Rmp UriQ3TLD52
Up-regulated during skeletal muscle growth protein 5 (Diabetes-associated protein in insulin-sensitive tissues)Usmg5 DapitQ78IK22
UPF0606 protein KIAA1549Kiaa1549Q68FD92
Uridine-cytidine kinase 2 (Fragment)Uck2A0A0B4J1E52
Uveal autoantigen with coiled-coil domains and ankyrin repeats (Uveal autoantigen with coiled-coil domains and ankyrin repeats, isoform CRA_b)Uaca mCG_127705A0A0R4J0S72
V-type proton ATPase 16 kDa proteolipid subunit (V-ATPase 16 kDa proteolipid subunit) (PL16) (Vacuolar proton pump 16 kDa proteolipid subunit)Atp6v0c Atp6c Atp6l Atpl MvpP630822
V-type proton ATPase subunit E 2 (V-ATPase subunit E 2) (Vacuolar proton pump subunit E 2)Atp6v1e2 Atp6e1Q9D5932
Vacuolar protein sorting-associated protein 37D (ESCRT-I complex subunit VPS37D) (Williams-Beuren syndrome region protein 24 homolog)Vps37d Wbscr24Q810I02
Valacyclovir hydrolase (VACVase) (Valacyclovirase) (EC 3.1.-.-) (Biphenyl hydrolase-like protein)BphlQ8R1642
Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS)Vars2 Kiaa1885 Vars2lQ3U2A82
Vang-like 2 (Van gogh, Drosophila), isoform CRA_b (Vang-like protein 2)Vangl2 mCG_4495D3YY752
Vascular endothelial growth factor AVegfaF8WH102
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Embryonic receptor kinase 2) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase receptor FLT)Flt1 Emrk2 Flt Vegfr1P359692
Versican core proteinVcanE9PYH02
Very long-chain-specific acyl-CoA dehydrogenase, mitochondrialAcadvlB1AR282
Vesicle-trafficking protein SEC22bSec22bE9Q6R32
Vitamin K epoxide reductase complex subunit 1-like protein 1 (VKORC1-like protein 1) (EC 1.17.4.4)Vkorc1l1Q6TEK52
Voltage-dependent anion-selective channel protein 3Vdac3J3QMG32
von Willebrand factorVwfE9QPU12
von Willebrand factor A domain-containing protein 9Vwa9Q8R3P62
WASH complex subunit 1 (WAS protein family homolog 1)Washc1 Orf19 Wash Wash1Q8VDD82
WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1)Wdhd1 And1P593282
WD repeat domain phosphoinositide-interacting protein 2 (WIPI-2)Wipi2Q80W472
WD repeat-containing protein 55Wdr55Q9CX972
WD repeat-containing protein 62Wdr62E9QK362
WD repeat-containing protein 75 (U3 small nucleolar RNA-associated protein 17 homolog)Wdr75 Utp17Q3U8212
WD repeat-containing protein 76Wdr76A6PWY42
Wilms tumor protein 1-interacting protein (WT1-interacting protein)WtipQ7TQJ82
Wings apart-like protein homolog (Dioxin-inducible factor 2) (DIF-2) (WAPL cohesin release factor)Wapl Kiaa0261 WapalQ65Z402
WNT1-inducible-signaling pathway protein 1 (WISP-1) (CCN family member 4) (ELM-1)Wisp1 Ccn4 Elm1O547752
WNT1-inducible-signaling pathway protein 2 (WISP-2) (CCN family member 5) (Connective tissue growth factor-like protein) (CTGF-L)Wisp2 Ccn5 CtgflQ9Z0G42
WolframinWfs1P566952
WW domain binding protein 1-like (Outcome predictor in acute leukemia 1 homolog)Wbp1l D19Wsu162e Opal1Q8BGW22
WW domain-binding protein 11 (WBP-11) (Splicing factor that interacts with PQBP-1 and PP1)Wbp11 Sipp1Q923D52
Xylosyltransferase 1Xylt1F8VPK62
Zinc finger BED domain-containing protein 4Zbed4 Kiaa0637Q80WQ92
Zinc finger CCCH domain-containing protein 14Zc3h14Q8BJ052
Zinc finger CCCH domain-containing protein 4Zc3h4 Kiaa1064Q6ZPZ32
Zinc finger CCCH type-containing 7BZc3h7bF8VPP82
Zinc finger E-box-binding homeobox 2 (Smad-interacting protein 1) (Zinc finger homeobox protein 1b)Zeb2 Sip1 Zfhx1b Zfx1bQ9R0G72
Zinc finger protein 385A (Hematopoietic zinc finger protein)Znf385a Hzf Zfp385aQ8VD122
Zinc finger protein 503 (Zinc finger protein Nolz-1)Znf503 Nolz1 Zfp503Q7TMA22
Zinc finger protein 593 (Zinc finger protein T86)Znf593 Zfp593Q9DB422
Zinc finger protein 609Znf609 Kiaa0295 Zfp609Q8BZ472
Zinc finger protein 638 (Nuclear protein 220) (Zinc finger matrin-like protein)Znf638 Np220 Zfml Zfp638Q614642
Zinc finger protein DZIP1L (DAZ-interacting protein 1-like protein)Dzip1lQ499E42
Zinc finger protein ZPR1 (Fragment)Zpr1F8WHU92
Zinc finger Ran-binding domain-containing protein 2 (Zinc finger protein 265) (Zinc finger, splicing)Zranb2 Zfp265 Zis Znf265Q9R0202
[F-actin]-methionine sulfoxide oxidase MICAL1Mical1E9PUI42
1,4-alpha-glucan-branching enzyme (Glucan (1,4-alpha-), branching enzyme 1, isoform CRA_a)Gbe1 mCG_127915G3UW301
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 4) (1-AGP acyltransferase 4) (1-AGPAT 4) (Lysophosphatidic acid acyltransferase delta) (LPAAT-delta)Agpat4Q8K4X71
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 5) (1-AGP acyltransferase 5) (1-AGPAT 5) (Lysophosphatidic acid acyltransferase epsilon) (LPAAT-epsilon)Agpat5 D8Ertd319eQ9D1E81
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (EC 2.3.1.51) (1-acylglycerol-3-phosphate O-acyltransferase 3) (1-AGP acyltransferase 3) (1-AGPAT 3) (Lysophosphatidic acid acyltransferase gamma) (LPAAT-gamma)Agpat3 Lpaat3Q9D5171
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-beta-2) (Phospholipase C-beta-2) (PLC-beta-2)Plcb2A3KGF71
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-1) (Phospholipase C-eta-1) (PLC-eta-1) (Phospholipase C-like protein 3) (PLC-L3)Plch1 Kiaa1069 Plcl3Q4KWH51
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)Plcg1 Plcg-1Q620771
116 kDa U5 small nuclear ribonucleoprotein componentEftud2G3UZ341
14-3-3 protein beta/alpha (Fragment)YwhabA2A5N11
14-3-3 protein gamma subtype (3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide)Ywhag 14-3-3 gamma mCG_1864A8IP691
14-3-3 protein theta (Fragment)YwhaqF6YY691
1700006A11Rik protein (MCG6275, isoform CRA_a) (RIKEN cDNA 1700006A11 gene)1700006A11Rik mCG_6275B9EHI31
2'-5'-oligoadenylate synthase 2 ((2-5')oligo(A) synthase 2) (2-5A synthase 2) (EC 2.7.7.84) (2',5'-oligoadenylate synthetase-like 11)Oas2 oasl11E9Q9A91
2'-5'-oligoadenylate synthase-like protein 2 (EC 2.7.7.84) (54 kDa 2'-5'-oligoadenylate synthase-like protein) (p54 OASL) (M1204)Oasl2Q9Z2F21
2-aminoethanethiol dioxygenase (EC 1.13.11.19) (Cysteamine dioxygenase)Ado Gm237Q6PDY21
2-cell-stage, variable group, member 1 (MCG129052) (Putative uncharacterized protein variable group of 2-cell-stage gene family) (Tcstv1 protein)Tcstv1 mCG_129052O706191
2-hydroxyacylsphingosine 1-beta-galactosyltransferase (EC 2.4.1.47) (Ceramide UDP-galactosyltransferase) (Cerebroside synthase) (UDP-galactose-ceramide galactosyltransferase)Ugt8 Cgt Ugt4 Ugt8aQ646761
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDE1A) (BCKDH E1-alpha)BckdhaP501361
24-hydroxycholesterol 7-alpha-hydroxylase (EC 1.14.14.26) (Cytochrome P450 39A1) (mCYP39A1) (Oxysterol 7-alpha-hydroxylase)Cyp39a1Q9JKJ91
28S ribosomal protein S10, mitochondrial (MRP-S10) (S10mt)Mrps10Q80ZK01
28S ribosomal protein S16, mitochondrial (MRP-S16) (S16mt)Mrps16 Rpms16Q9CPX71
28S ribosomal protein S17, mitochondrial (Fragment)Mrps17D3Z1981
28S ribosomal protein S18a, mitochondrial (Mitochondrial ribosomal protein S18A, isoform CRA_a)Mrps18a mCG_2525D3Z6031
28S ribosomal protein S18a, mitochondrial (MRP-S18-a) (Mrps18a) (S18mt-a) (28S ribosomal protein S18-3, mitochondrial) (MRP-S18-3)Mrps18aQ99N851
28S ribosomal protein S2, mitochondrial (MRP-S2) (S2mt)Mrps2Q924T21
28S ribosomal protein S23, mitochondrial (Fragment)Mrps23A7M7Q81
28S ribosomal protein S23, mitochondrial (Mitochondrial ribosomal protein S23, isoform CRA_b) (Putative uncharacterized protein)Mrps23 mCG_7673Q3TI141
28S ribosomal protein S23, mitochondrial (MRP-S23) (S23mt)Mrps23Q8VE221
28S ribosomal protein S28, mitochondrial (MRP-S28) (S28mt)Mrps28Q9CY161
28S ribosomal protein S29, mitochondrialDap3G3X9M01
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