EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
28S ribosomal protein S29, mitochondrialDap3A0A0R4J1B91
28S ribosomal protein S35, mitochondrialMrps35A0A0R4J0L61
28S ribosomal protein S35, mitochondrial (MRP-S35) (S35mt)Mrps35Q8BJZ41
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (Fragment)EbpA2AC291
3-hydroxyanthranilate 3,4-dioxygenase (EC 1.13.11.6) (3-hydroxyanthranilate oxygenase) (3-HAO) (3-hydroxyanthranilic acid dioxygenase) (HAD)HaaoQ78JT31
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase)HibchE0CX191
3-keto-steroid reductase (EC 1.1.1.270) (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62)Hsd17b7O887361
3-ketoacyl-CoA thiolase B, peroxisomal (EC 2.3.1.16) (Acetyl-CoA acyltransferase B) (Beta-ketothiolase B) (Peroxisomal 3-oxoacyl-CoA thiolase B)Acaa1b Acaa1Q8VCH01
3-ketodihydrosphingosine reductase (KDS reductase) (EC 1.1.1.102) (3-dehydrosphinganine reductase) (Follicular variant translocation protein 1 homolog) (FVT-1)Kdsr Fvt1Q6GV121
3-oxo-5-beta-steroid 4-dehydrogenase (EC 1.3.1.3) (Aldo-keto reductase family 1 member D1) (Delta(4)-3-ketosteroid 5-beta-reductase) (Delta(4)-3-oxosteroid 5-beta-reductase)Akr1d1Q8VCX11
3-phosphoinositide-dependent protein kinase 1Pdpk1F2Z3X61
3-phosphoinositide-dependent protein kinase 1Pdpk1F2Z4001
3-phosphoinositide-dependent protein kinase 1Pdpk1F2Z3Z91
3-phosphoinositide-dependent protein kinase 1 (mPDK1) (EC 2.7.11.1)Pdpk1 Pdk1Q9Z2A01
3-phosphoinositide-dependent protein kinase 1 (Putative uncharacterized protein)Pdpk1Q3TRL21
39S ribosomal protein L10, mitochondrial (L10mt) (MRP-L10)Mrpl10Q3TBW21
39S ribosomal protein L13, mitochondrial (L13mt) (MRP-L13)Mrpl13Q9D1P01
39S ribosomal protein L16, mitochondrial (L16mt) (MRP-L16)Mrpl16Q99N931
39S ribosomal protein L17, mitochondrial (L17mt) (MRP-L17)Mrpl17Q9D8P41
39S ribosomal protein L2, mitochondrialMrpl2B1B1D81
39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)Mrpl2Q9D7731
39S ribosomal protein L20, mitochondrial (L20mt) (MRP-L20)Mrpl20Q9CQL41
39S ribosomal protein L24, mitochondrial (L24mt) (MRP-L24)Mrpl24Q9CQ061
39S ribosomal protein L27, mitochondrial (L27mt) (MRP-L27)Mrpl27Q99N921
39S ribosomal protein L3, mitochondrialMrpl3F6W7C71
39S ribosomal protein L3, mitochondrial (L3mt) (MRP-L3)Mrpl3Q99N951
39S ribosomal protein L3, mitochondrial (Mitochondrial ribosomal protein L3, isoform CRA_a)Mrpl3 mCG_14748D3Z4561
39S ribosomal protein L32, mitochondrial (L32mt) (MRP-L32) (Heart-expressed gene 1 protein)Mrpl32 Heg1Q9DCI91
39S ribosomal protein L40, mitochondrial (L40mt) (MRP-L40) (Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog)Mrpl40 NlvcfQ9Z2Q51
39S ribosomal protein L43, mitochondrial (L43mt) (MRP-L43) (Mitochondrial ribosomal protein bMRP36a)Mrpl43Q99N891
39S ribosomal protein L45, mitochondrial (Fragment)Mrpl45F6QAU71
39S ribosomal protein L45, mitochondrial (L45mt) (MRP-L45)Mrpl45Q9D0Q71
39S ribosomal protein L46, mitochondrial (L46mt) (MRP-L46)Mrpl46Q9EQI81
39S ribosomal protein L48, mitochondrialMrpl48E9QPQ81
39S ribosomal protein L53, mitochondrial (L53mt) (MRP-L53)Mrpl53Q9D1H81
39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9)Mrpl9Q99N941
39S ribosomal protein L9, mitochondrial (Putative uncharacterized protein)Mrpl9Q3UK021
4-hydroxyphenylpyruvate dioxygenase (Fragment)HpdF6X9Z61
40S ribosomal protein S15a (Fragment)Rps15aF8WJ411
40S ribosomal protein S15a (Fragment)Rps15aD3Z7121
40S ribosomal protein S19 (Fragment)Rps19D3YUG31
40S ribosomal protein S26Rps26 mCG_18667 mCG_9347Q497N11
40S ribosomal protein S27Rps27l mCG_1230D3YYB01
40S ribosomal protein S3Rps3D3YV431
40S ribosomal protein S30Fau Gm9843 mCG_11741Q642K51
40S ribosomal protein S4Rps4l 1110033J19Rik Rps4y2 mCG_49215Q3V1Z51
4Cytl1 protein (Fragment)Cytl1 4Cytl1 Cyt1Q6P5361
4F2 cell-surface antigen heavy chain (Fragment)Slc3a2A0A0U1RP321
5'-3' exoribonuclease 1Xrn1F8VQ871
5'-AMP-activated protein kinase subunit beta-1 (Protein kinase, AMP-activated, beta 1 non-catalytic subunit, isoform CRA_a)Prkab1 mCG_20709S4R2R11
5'-AMP-activated protein kinase subunit gamma-2 (Fragment)Prkag2D3YUS11
5'-AMP-activated protein kinase subunit gamma-2 (Putative uncharacterized protein)Prkag2Q8BIQ91
5'-nucleotidase domain containing 2 (5'-nucleotidase domain-containing 2)Nt5dc2Q91X761
5'-nucleotidase domain-containing protein 1Nt5dc1E9QN011
5'-nucleotidase, cytosolic II, isoform CRA_b (Cytosolic purine 5'-nucleotidase)Nt5c2 mCG_22001G3X9J61
5-azacytidine-induced protein 2 (Fragment)Azi2D3Z7S31
5-azacytidine-induced protein 2 (Fragment)Azi2F7A0921
5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1)Azi2 Az2 Nap1 Tbkp2Q9QYP61
5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) (5,10-methenyl-tetrahydrofolate synthetase) (MTHFS) (Methenyl-THF synthetase)MthfsQ9D1101
5-hydroxyisourate hydrolase (HIU hydrolase) (HIUHase) (EC 3.5.2.17) (Transthyretin-related protein)UrahQ9CRB31
5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4) (Sperm head and tail associated protein)Nsun4 ShtapQ9CZ571
52 kDa repressor of the inhibitor of the protein kinase (p52rIPK) (58 kDa interferon-induced protein kinase-interacting protein) (p58IPK-interacting protein) (THAP domain-containing protein 0) (THAP domain-containing protein 12)Thap12 Prkrir Thap0Q9CUX11
55 kDa erythrocyte membrane proteinMpp1A2AN841
55 kDa erythrocyte membrane protein (Fragment)Mpp1B7ZCM01
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2 (6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2, isoform CRA_b) (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2) (Putative uncharacterized protein)Pfkfb2 mCG_2633Q6GTL71
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 2, isoform CRA_a (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 variant 5) (EC 2.7.1.105) (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2)Pfkfb2 mCG_2633B2Z8931
6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 variant 4 (EC 2.7.1.105) (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2)Pfkfb2B2Z8921
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (6PF-2-K/Fru-2,6-P2ase 2) (PFK/FBPase 2) (6PF-2-K/Fru-2,6-P2ase heart-type isozyme) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)]Pfkfb2P702651
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)PgdQ91YT91
6-phosphogluconolactonase (6-phosphogluconolactonase, isoform CRA_b)Pgls mCG_10369D3Z4X11
6-phosphogluconolactonase (Putative uncharacterized protein)PglsQ8CBG61
6.8 kDa mitochondrial proteolipidMp68P563791
60S ribosomal protein L18aRpl18aQ3THJ01
60S ribosomal protein L23 (Fragment)Rpl23A2A6F81
60S ribosomal protein L29Rpl29 Gm10709 mCG_19505D3Z1N91
60S ribosomal protein L29Gm3550 mCG_123916W4VSN71
60S ribosomal protein L5 (Fragment)Rpl5D3YYV81
60S ribosomal protein L9Rpl9D3Z6291
60S ribosome subunit biogenesis protein NIP7 homologNip7E9Q1091
72 kDa inositol polyphosphate 5-phosphatase (EC 3.1.3.36) (Phosphatidylinositol 4,5-bisphosphate 5-phosphatase) (Phosphatidylinositol polyphosphate 5-phosphatase type IV)Inpp5eQ9JII11
85/88 kDa calcium-independent phospholipase A2 (CaI-PLA2) (EC 3.1.1.4) (Group VI phospholipase A2) (GVI PLA2) (Intracellular membrane-associated calcium-independent phospholipase A2 beta) (iPLA2-beta) (Patatin-like phospholipase domain-containing protein 9) (PNPLA9)Pla2g6 Pnpla9P978191
A disintegrin and metallopeptidase domain 6B (ADAM6b)Adam6bQ6IMH71
A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAM-TS 13) (ADAM-TS13) (ADAMTS-13) (EC 3.4.24.87) (von Willebrand factor-cleaving protease) (vWF-CP) (vWF-cleaving protease)Adamts13 Gm710Q769J61
A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI)Adamts2Q8C9W31
A disintegrin and metalloproteinase with thrombospondin motifs 20 (ADAM-TS 20) (ADAM-TS20) (ADAMTS-20) (EC 3.4.24.-)Adamts20P595111
A disintegrin and metalloproteinase with thrombospondin motifs 4 (Putative uncharacterized protein)Adamts4Q3TNX81
A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAM-TS 8) (ADAM-TS8) (ADAMTS-8) (EC 3.4.24.-) (METH-2)Adamts8P571101
A disintegrin-like and metallopeptidase (Reprolysin type) with thrombospondin type 1 motif, 14 (A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14) (MCG122067)Adamts14 mCG_122067B2RXX51
A kinase (PRKA) anchor protein 11Akap11E9Q7741
A kinase (PRKA) anchor protein 11Akap11E9Q7771
A-kinase anchor protein 10, mitochondrial (AKAP-10) (Dual specificity A kinase-anchoring protein 2) (D-AKAP-2) (Protein kinase A-anchoring protein 10) (PRKA10)Akap10O888451
A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc)Akap13 BrxE9Q3941
A-kinase anchor protein 2Akap2A2API81
A-kinase anchor protein 3 (AKAP-3) (A-kinase anchor protein 110 kDa) (AKAP 110) (Protein kinase A-anchoring protein 3) (PRKA3)Akap3 Akap110O889871
A-kinase anchor protein 8-like (AKAP8-like protein) (Neighbor of A-kinase-anchoring protein 95) (Neighbor of AKAP95)Akap8l Nakap Nakap95Q9R0L71
A-kinase anchor protein 9Akap9E9QQ101
A230054D04Rik protein (Fragment)Bod1l A230054D04Rik AF013969Q6P8H71
Abelson tyrosine-protein kinase 2 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 2) (Abelson-related gene protein) (Tyrosine-protein kinase ARG)Abl2 ArgQ4JIM51
ABI gene family member 3 (New molecule including SH3) (Nesh)Abi3 NeshQ8BYZ11
Abl interactor 1Abi1B7ZCU01
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