EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Advillin (Actin-binding protein DOC6) (p92)Avil AdvilO883981
AF4/FMR2 family member 2 (FMR2P) (Fragile X mental retardation protein 2 homolog) (Protein FMR-2) (Protein Ox19)Aff2 Fmr2 Ox19O551121
AfadinAfdnE9PYX71
AgrinAgrnZ4YK851
AHNAK nucleoprotein 2Ahnak2 AI450948Q3URZ61
AHNAK nucleoprotein 2 (Fragment)Ahnak2E9PYB01
Alanine aminotransferase 2 (ALT2) (EC 2.6.1.2) (Glutamate pyruvate transaminase 2) (GPT 2) (Glutamic--alanine transaminase 2) (Glutamic--pyruvic transaminase 2)Gpt2 Aat2Q8BGT51
Alanine--tRNA ligase, mitochondrial (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS)Aars2 Aarsl Gm89 Kiaa1270Q14CH71
Albumin 1 (Putative uncharacterized protein) (Serum albumin)Alb alb Alb1 mCG_1705Q546G41
Aldehyde dehydrogenaseAldh3a2B1ATI01
Aldehyde dehydrogenaseAldh3a2B1AV771
Aldehyde dehydrogenase family 8 member A1 (EC 1.2.1.-) (Retinal dehydrogenase 4)Aldh8a1 Raldh4Q8BH001
Aldhehyde dehydrogenase family 5, subfamily A1Aldh5a1 mCG_3145B2RS411
Aldo-keto reductase family 1, member B10 (aldose reductase) (MCG142264, isoform CRA_c)Akr1b10 mCG_142264S4R2G91
Aldo-keto reductase family 1, member C20 (MCG9092, isoform CRA_b) (Putative uncharacterized protein)Akr1c20 mCG_9092Q9CZU01
Alkaline phosphatase, tissue-nonspecific isozyme (AP-TNAP) (TNSALP) (EC 3.1.3.1) (Alkaline phosphatase 2) (Alkaline phosphatase liver/bone/kidney isozyme)Alpl Akp-2 Akp2P092421
All-trans-retinol 13,14-reductaseRetsatH3BJ511
All-trans-retinol 13,14-reductase (EC 1.3.99.23) (All-trans-13,14-dihydroretinol saturase) (RetSat) (PPAR-alpha-regulated and starvation-induced gene protein)Retsat PpsigQ64FW21
Allograft inflammatory factor 1-like (Ionized calcium-binding adapter molecule 2)Aif1l Iba2Q9EQX41
Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase)Fut8Q9WTS21
Alpha-(1,6)-fucosyltransferase (EC 2.4.1.68)Fut8Q3UYN71
alpha-1,2-Mannosidase (EC 3.2.1.-)Man1c1 mCG_12952Q6NXK91
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Fragment)Mgat1J3JS241
Alpha-1-acid glycoprotein 2 (AGP 2) (Orosomucoid-2) (OMD 2)Orm2 Agp-2 Orm-2P073611
Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Syntrophin-1)Snta1 Snt1Q612341
Alpha-1B-glycoprotein (Alpha-1-B glycoprotein)A1bgQ19LI21
Alpha-adducinAdd1E9Q1K31
Alpha-adducinAdd1F8WGR01
Alpha-adducinAdd1F8WHZ91
Alpha-adducin (Fragment)Add1A0A0J9YVI41
Alpha-aminoadipic semialdehyde dehydrogenaseAldh7a1G3UYR81
Alpha-endosulfine (ARPP-19e)EnsaP608401
Alpha-enolase (Eno1 protein)Eno1Q6PHC11
Alpha-globin mRNA (Fragment)0Q616491
Alpha-globin transcription factor CP2Tfcp2 Tcfcp2Q9ERA01
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3Alkbh3A2AKV61
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (EC 1.14.11.54) (Alkylated DNA repair protein alkB homolog 3) (mAbh3)Alkbh3 Abh3Q8K1E61
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Fragment)Alkbh3A2AKV71
Alpha-mannosidase (EC 3.2.1.-)Man2a2 mCG_19442Q197W71
Alpha-mannosidase (EC 3.2.1.-)Man2c1E9PZ881
Alpha-mannosidase (EC 3.2.1.-)Man2c1F8WIE11
Alpha-mannosidase 2x (EC 3.2.1.114) (Alpha-mannosidase IIx) (Man IIx) (Mannosidase alpha class 2A member 2) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)Man2a2 Mana2xQ8BRK91
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (EC 2.4.99.7) (NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc-alpha-2,6-sialyltransferase) (ST6GalNAc IV) (ST6GalNAcIV) (Sialyltransferase 7D) (SIAT7-D)St6galnac4 Siat7dQ9R2B61
Alpha-protein kinase 1 (EC 2.7.11.-) (Lymphocyte alpha-protein kinase)Alpk1 Kiaa1527 LakQ9CXB81
Alpha-sarcoglycan (Alpha-SG) (50 kDa dystrophin-associated glycoprotein) (50DAG) (Adhalin)SgcaP823501
AlphaCstF-64 variant 4 (Cleavage stimulation factor subunit 2)Cstf2A2AEK11
AmeloblastinAmbnO551891
Amine oxidase (EC 1.4.3.-)MaoaQ3U2X51
Amine oxidase [flavin-containing] B (EC 1.4.3.4) (Monoamine oxidase type B) (MAO-B)MaobQ8BW751
Amino acid transporterSlc1a5Q5U6471
Amino acid transporterSlc1a3 mCG_3300Q543U31
Aminomethyltransferase, mitochondrial (EC 2.1.2.10) (Glycine cleavage system T protein) (GCVT)AmtQ8CFA21
Aminopeptidase (EC 3.4.11.-)NpeppsE9Q0391
AMP deaminase 3 (Fragment)Ampd3D3YU731
AMP-binding enzyme (Fragment)Ampbp2Q99M721
AmphiphysinAmphA0A0G2JEG81
Amphiregulin (AR) (Schwannoma-derived growth factor) (SDGF)Areg SdgfP319551
Amylo-1,6-glucosidase, 4-alpha-glucanotransferase (Fragment)AglF6XXE61
Amyloid-like protein 1 (APLP) (APLP-1) [Cleaved into: C30]Aplp1Q031571
AN1-type zinc finger protein 2B (Arsenite-inducible RNA-associated protein-like protein) (AIRAP-like protein)Zfand2b AiraplQ91X581
Anamorsin (Fragment)Ciapin1E0CYY11
Anaphase-promoting complex subunit 1Anapc1A2ATQ51
Anaphase-promoting complex subunit 2 (Fragment)Anapc2A2AI111
Ancient ubiquitous protein 1Aup1P702951
Angio-associated migratory proteinAampJ3QN891
Angiopoietin-2 (ANG-2)Angpt2 Agpt2O356081
Angiopoietin-like protein 8 (Betatrophin) (Lipasin) (Refeeding-induced fat and liver protein)Angptl8 Gm6484 RiflQ8R1L81
Angiopoietin-related protein 3 (Angiopoietin-like protein 3) [Cleaved into: ANGPTL3(17-224)]Angptl3Q9R1821
Anion exchange proteinSlc4a4 slc4a4A7E1Z51
Anion exchange proteinSlc4a4E9Q8N81
Anion exchange protein (Fragment)Slc4a7Q8BWZ41
Ankyrin repeat and KH domain-containing 1Ankhd1E9PUR01
Ankyrin repeat and KH domain-containing 1Ankhd1E9Q1M61
Ankyrin repeat and KH domain-containing 1 (Fragment)Ankhd1F7C5451
Ankyrin repeat and LEM domain-containing protein 1 (EC 3.1.-.-) (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3)Ankle1 Ankrd41 Lem3A8VU901
Ankyrin repeat and MYND domain-containing protein 1Ankmy1Q8C0W11
Ankyrin repeat and SOCS box protein 6 (ASB-6)Asb6Q91ZU11
Ankyrin repeat and zinc finger domain-containing protein 1Ankzf1 D1Ertd161eQ80UU11
Ankyrin repeat and zinc finger domain-containing protein 1 (MCG133867, isoform CRA_c)Ankzf1 mCG_133867J3QM811
Ankyrin repeat domain-containing protein 17Ankrd17E9Q8041
Ankyrin repeat domain-containing protein 17Ankrd17E9QKG61
Ankyrin repeat domain-containing protein 26Ankrd26D3Z4821
Ankyrin repeat domain-containing protein 37Ankrd37Q569N21
Ankyrin-2Ank2S4R2F31
Ankyrin-2Ank2S4R2R51
AnnexinAnxa2Q9CZI71
Annexin (Fragment)Anxa4D3Z0S11
AnoctaminAno1G8JL821
Anoctamin-10 (Transmembrane protein 16K)Ano10 Tmem16kQ8BH791
Antigen-presenting glycoprotein CD1d1 (CD antigen CD1d.1)Cd1d1 Cd1.1P116091
AP complex subunit betaAp4b1 Gm43064B0V3P31
AP complex subunit betaAp2b1H3BIY91
AP-1 complex subunit beta-1Ap1b1Q5SVG41
AP-1 complex subunit gamma-like 2 (Gamma2-adaptin) (G2ad)Ap1g2O885121
AP-2 complex subunit betaAp2b1H3BKM01
AP-3 complex subunit mu-2 (Adaptor-related protein complex 3 subunit mu-2) (Clathrin assembly protein assembly protein complex 3 mu-2 medium chain) (Clathrin coat assembly protein AP47 homolog 2) (Clathrin coat-associated protein AP47 homolog 2) (Golgi adaptor AP-1 47 kDa protein homolog 2) (HA1 47 kDa subunit homolog 2) (Mu3B-adaptin) (m3B) (P47B)Ap3m2Q8R2R91
AP-4 complex subunit beta-1Ap4b1B0V3P41
AP-4 complex subunit beta-1 (AP-4 adaptor complex subunit beta) (Adaptor-related protein complex 4 subunit beta-1) (Beta subunit of AP-4) (Beta4-adaptin)Ap4b1Q9WV761
AP-4 complex subunit mu-1 (AP-4 adaptor complex mu subunit) (Adaptor-related protein complex 4 subunit mu-1) (Mu subunit of AP-4) (Mu-adaptin-related protein 2) (mu-ARP2) (Mu4-adaptin) (mu4)Ap4m1Q9JKC71
AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5)Ap5z1 Kiaa0415Q3U8291
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