EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
CD44 antigen (Cd44 protein)Cd44Q80X371
CD99 antigen (Paired immunoglobin-like type 2 receptor-ligand) (PILR-L) (CD antigen CD99)Cd99 PilrlQ8VCN61
CD99 antigen-like protein 2 (Cd99 antigen-like 2, isoform CRA_c)Cd99l2 mCG_113782A2AP741
CDC16 cell division cycle 16 homolog (S. cerevisiae), isoform CRA_e (Putative uncharacterized protein)Cdc16 mCG_3710Q3TI841
Cdc42 effector protein 1Cdc42ep1A0A0R4J0S11
CDE1-binding protein CDEBPAplp2 CdebpQ614821
CDGSH iron-sulfur domain-containing protein 2 (RIKEN cDNA 1500009M05, isoform CRA_b)Cisd2 1500009M05Rik mCG_22363D3Z3X41
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48)Cdk5rap2 Kiaa1633Q8K3891
CDK5 regulatory subunit-associated protein 3Cdk5rap3Q99LM21
CDKN2AIP N-terminal-like protein (CDKN2A-interacting protein N-terminal-like protein)Cdkn2aipnl D11Ertd497e MNCb-1520Q9D2111
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (Fragment)Pgs1F8WI041
Cds2 protein (Phosphatidate cytidylyltransferase 2) (Putative uncharacterized protein)Cds2Q6PBC01
Cell cycle control protein 50ATmem30aD3YVV11
Cell cycle progression 1, isoform CRA_d (Cell cycle progression protein 1)Ccpg1 mCG_8032D3Z7R91
Cell cycle progression protein 1Ccpg1Q640L31
Cell death activator CIDE-A (Cell death-inducing DFFA-like effector A)CideaO703021
Cell division cycle protein 27 homologCdc27A2A6Q51
Cell division cycle-associated protein 3 (Fragment)Cdca3D3YXE31
Cell division cycle-associated protein 3 (Fragment)Cdca3D3YZ811
Cell division cycle-associated protein 3 (Fragment)Cdca3D3Z3H61
Centrin-1 (Caltractin)Cetn1 CaltP412091
Centrin-2Cetn2Z4YJH11
Centrin-2 (Caltractin isoform 1)Cetn2 CaltQ9R1K91
Centriole, cilia and spindle-associated proteinCcsapQ8QZT21
Centromere protein FCenpfE9Q3P41
Centrosomal protein of 131 kDaCep131 Azi1J3QMP91
Centrosomal protein of 131 kDa (5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)Cep131 Az1 Azi Azi1Q620361
Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2)Cep97 Lrriq2Q9CZ621
Centrosome-associated protein 350 (Cep350)Cep350 Kiaa0480E9Q3091
Centrosome-associated protein CEP250Cep250A3KGJ71
Centrosome-associated protein CEP250Cep250E9Q5A81
Ceramide kinase (mCERK) (EC 2.7.1.138) (Acylsphingosine kinase)CerkQ8K4Q71
Ceramide synthase 2 (CerS2) (LAG1 longevity assurance homolog 2) (Translocating chain-associating membrane protein homolog 3) (TRAM homolog 3)Cers2 Lass2 Trh3Q924Z41
Ceramide synthase 2 (Fragment)Cers2 Lass2D3YTM01
Ceramide synthase 2 (Fragment)Cers2 Lass2D3Z0Z21
Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5) (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4)Cers5 Lass5 Trh4Q9D6K91
Cerebellar degeneration-related protein 2-likeCdr2l Gm21A2A6T11
Cerebral cavernous malformations protein 2 homologCcm2F7AVU11
Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor)Cdnf Armetl1Q8CC361
Ceruloplasmin (Ceruloplasmin, isoform CRA_f)Cp mCG_19773G3X9T81
Chaperonin subunit 2 (Beta), isoform CRA_a (Putative uncharacterized protein)Cct2 mCG_17329Q542X71
Chloride channel CLIC-like 1, isoform CRA_a (Chloride channel CLIC-like protein 1)Clcc1 mCG_4070A2AEM21
Chloride channel CLIC-like protein 1Clcc1Q99LI21
Chloride channel proteinClcn6A2A7F61
Chloride channel proteinClcn5B1ATV01
Chloride channel proteinClcn3E9Q2I11
Chloride channel proteinClcn3Q3TF451
Chloride channel proteinClcn3Q8K4W81
Chloride channel proteinClcn7E9PYL41
Chloride transport protein 6Clcn6E9Q7411
Chloride transport protein 6 (Chloride channel protein 6) (ClC-6)Clcn6 Clc6O354541
Choline transporter-like protein 1Slc44a1A2AMH51
Choline transporter-like protein 1Slc44a1A2AMH31
Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1)Chsy1 Kiaa0990Q6ZQ111
Chordin-like protein 1 (Neuralin-1) (Neurogenesin-1) (Ventroptin)Chrdl1 Ng1 Nrln1Q920C11
Chromatin target of PRMT1 proteinChtop 2500003M10RikE9PW201
Chromatin target of PRMT1 protein (Fragment)Chtop 2500003M10RikD3YZA11
Chromatin target of PRMT1 protein (Fragment)Chtop 2500003M10RikD3Z7T71
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (mPc3)Cbx8 Pc3Q9QXV11
Chromodomain-helicase-DNA-binding protein 2 (CHD-2) (EC 3.6.4.12) (ATP-dependent helicase CHD2)Chd2E9PZM41
Chromodomain-helicase-DNA-binding protein 8 (Fragment)Chd8F7AL761
Chromogranin B (Putative uncharacterized protein)Chgb mCG_19486Q3TY661
Chromosome transmission fidelity protein 18 homologChtf18 Ctf18Q8BIW91
Cilia- and flagella-associated protein 36 (Fragment)Cfap36 Ccdc104Q5SNY81
Cilia- and flagella-associated protein 57 (WD repeat-containing protein 65)Cfap57 Wdr65Q9D1801
Cilia- and flagella-associated protein 91 (CFAP91) (AMY-1-associating protein expressed in testis 1 homolog) (AAT-1) (MYCBP/AMY-1-associated testis-expressed protein 1) (Protein MAATS1)Maats1 Aat1 Cfap91 Spata26Q8BRC61
Cingulin-like protein 1 (Junction-associated coiled-coil protein)Cgnl1 Jacop Kiaa1749Q6AW691
Cis-retinol/3alpha hydroxysterol short-chain dehydrogenase-like protein (Putative uncharacterized protein) (RDH16 family member 2)Rdh16f2 BC089597Q8K3M11
Citrate lyase subunit beta-like protein, mitochondrial (Citrate lyase beta-like) (Beta-methylmalate synthase) (EC 2.3.3.-) (Malate synthase) (EC 2.3.3.9)Clybl ClbQ8R4N01
Citrate synthaseCsl mCG_19869Q80X681
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Rho-interacting, serine/threonine-protein kinase 21)Cit CrikP490251
CKLF-like MARVEL transmembrane domain-containing protein 3 (Chemokine-like factor superfamily member 3)Cmtm3 Cklfsf3Q99LJ51
CKLF-like MARVEL transmembrane domain-containing protein 4 (Chemokine-like factor superfamily member 4)Cmtm4 Cklfsf4Q8CJ611
CKLF-like MARVEL transmembrane domain-containing protein 5 (Chemokine-like factor superfamily member 5)Cmtm5 Cklfsf5Q9D6G91
Clathrin coat assembly protein AP180Snap91E9Q9A31
Clathrin coat assembly protein AP180 (91 kDa synaptosomal-associated protein) (Clathrin coat-associated protein AP180) (Phosphoprotein F1-20)Snap91Q615481
Clathrin light chainClta mCG_16456B1AWD81
Clathrin light chainCltaB1AWE11
Claudin-2Cldn2O885521
Claudin-9Cldn9Q9Z0S71
Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (Clipper homolog) (Clipper/CPSF 30K)Cpsf4 Cpsf30Q8BQZ51
Cleavage and polyadenylation-specificity factor subunit 6Cpsf6H3BJ301
Cleavage and polyadenylation-specificity factor subunit 6Cpsf6H3BJW31
Cleavage stimulation factor subunit 2 (Fragment)Cstf2A2AEJ81
Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein)Clptm1lQ8BXA51
CLIP associating protein 2 (CLIP-associating protein 2)Clasp2Q08EB61
CLIP-associating protein 1Clasp1E9QKH01
CLIP-associating protein 1Clasp1E9QNY91
CLIP-associating protein 1Clasp1J3QP811
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 (Alpha 2,3-ST 2) (Beta-galactoside alpha-2,3-sialyltransferase 2) (EC 2.4.99.4) (Gal-NAc6S) (Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase) (ST3Gal II) (ST3GalII) (ST3GalA.2) (Sialyltransferase 4B) (SIAT4-B)St3gal2 Siat4b Siat5Q112041
Coagulation factor VIII (Procoagulant component)F8 Cf8 F8cQ061941
Coagulation factor X (Putative uncharacterized protein)F10Q3U3V11
Coatomer subunit alphaCopaF8WHL21
Coatomer subunit epsilon (Fragment)CopeD3Z3151
Coatomer subunit zeta-2 (Zeta-2-coat protein) (Zeta-2 COP)Copz2Q9JHH91
Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (EC 2.5.1.17) (Cob(I)alamin adenosyltransferase) (Methylmalonic aciduria type B homolog)MmabQ9D2731
Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1)Stag1 Sa1Q9D3E61
Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein)Cchcr1 HcrQ8K2I21
Coiled-coil and C2 domain-containing protein 1ACc2d1aE9PX941
Coiled-coil domain containing 53, isoform CRA_c (WASH complex subunit 3)Washc3 Ccdc53 mCG_16785G3UWG71
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