EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Cysteine protease (EC 3.4.22.-)Atg4bA0A0R4J0651
Cysteine-rich hydrophobic domain-containing protein 1 (Brain X-linked protein)Chic1 BrxQ8CBW71
Cysteine-rich secretory protein 1 (CRISP-1) (Acidic epididymal glycoprotein 1) (Sperm-coating glycoprotein 1) (SCP 1)Crisp1 Aeg-1 Aeg1Q034011
Cysteine-rich with EGF-like domain protein 1Creld1Q91XD71
Cytidine and dCMP deaminase domain-containing protein 1Cdadc1Q8BMD51
Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase)Cda CddP563891
Cytochrome b-245 light chain (Cytochrome b(558) alpha chain) (Cytochrome b558 subunit alpha) (Neutrophil cytochrome b 22 kDa polypeptide) (Superoxide-generating NADPH oxidase light chain subunit) (p22 phagocyte B-cytochrome) (p22-phox) (p22phox)CybaQ614621
Cytochrome c (Cytochrome c, somatic) (MCG119910) (Putative uncharacterized protein)Cycs CYCS mCG_119910Q56A151
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial (Coiled-coil domain-containing protein 56)Coa3 Ccdc56Q9D2R61
Cytochrome c oxidase assembly protein COX15 homologCox15Q8BJ031
Cytochrome c oxidase protein 20 homologCox20 Fam36aQ9D7J41
Cytochrome c oxidase subunit 1 (EC 1.9.3.1)mt-Co1 Co1 COI COX1 COXIQ9MD681
Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)Mtco1 COI mt-Co1P003971
Cytochrome c oxidase subunit 6A, mitochondrial (Cytochrome c oxidase polypeptide VIa)Cox6a1 mCG_19235Q9DCW51
Cytochrome c oxidase subunit 6A2, mitochondrial (Cytochrome c oxidase polypeptide VIa-heart) (COXVIAH)Cox6a2P430231
Cytochrome c oxidase subunit IV isoform 1 (Cytochrome c oxidase subunit IV isoform 1, isoform CRA_b)Cox4i1 mCG_21200A2RSV81
Cytochrome P450 2A12 (EC 1.14.14.1) (CYPIIA12) (Steroid hormones 7-alpha-hydroxylase) (Testosterone 7-alpha-hydroxylase)Cyp2a12P565931
Cytohesin 2 (Cytohesin-2) (Pleckstrin homology, Sec7 and coiled-coil domains 2, isoform CRA_a) (Putative uncharacterized protein)Cyth2 Pscd2 mCG_10321Q99KH21
Cytohesin-1 (Pleckstrin homology, Sec7 and coiled-coil domains 1, isoform CRA_b) (Fragment)Cyth1 Pscd1 mCG_142715A2A5171
Cytohesin-1 (Putative uncharacterized protein)Cyth1 Pscd1Q3TZ021
Cytohesin-3 (Pleckstrin homology, Sec7 and coiled-coil domains 3, isoform CRA_b)Cyth3 Pscd3 mCG_17964G5E8Q41
Cytokine receptor-like factor 3Crlf3J3QMV51
Cytokine-dependent hematopoietic cell linker (Mast cell immunoreceptor signal transducer)Clnk MistQ9QZE21
Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)Dync1i1 Dnci1 Dncic1O884851
Cytoplasmic dynein 1 intermediate chain 2Dync1i2A2BFF51
Cytoplasmic dynein 1 intermediate chain 2 (Dynein cytoplasmic 1 intermediate chain 2, isoform CRA_a) (Putative uncharacterized protein)Dync1i2 mCG_19348Q3TPJ81
Cytoplasmic dynein 2 heavy chain 1Dync2h1D3Z0251
Cytoplasmic dynein 2 light intermediate chain 1 (mD2LIC)Dync2li1 D2licQ8K0T21
Cytoplasmic FMR1-interacting protein 2 (Fragment)Cyfip2F6QD741
Cytoplasmic polyadenylation element-binding protein 4Cpeb4Q5SU481
Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (mCPEB-4)Cpeb4 Kiaa1673Q7TN981
Cytoplasmic polyadenylation element-binding protein 4 (Fragment)Cpeb4Q5SU471
Cytoplasmic protein NCK1 (Non-catalytic region of tyrosine kinase adaptor protein 1, isoform CRA_b) (Putative uncharacterized protein)Nck1 mCG_19501Q8BH991
Cytoplasmic tRNA 2-thiolation protein 1 (EC 2.7.7.-) (ATP-binding domain-containing protein 3) (Cytoplasmic tRNA adenylyltransferase 1)Ctu1 Atpbd3 Ncs6Q99J101
Cytoplasmic tRNA 2-thiolation protein 2Ctu2 Ncs2Q3U3081
Cytoplasmic tRNA 2-thiolation protein 2Ctu2 CTU2 NCS2G3UXB41
Cytoskeleton-associated protein 5Ckap5K3W4R51
Cytosolic acyl coenzyme A thioester hydrolaseAcot7E9PYH21
Cytotoxic granule-associated RNA binding protein 1, isoform CRA_f (Nucleolysin TIA-1)Tia1 mCG_130509G5E8L21
D-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.-)D2hgdhQ8CIM31
D030074E01Rik protein (Fragment)Trappc8 D030074E01RikQ811K71
DAZ-associated protein 1 (Fragment)Dazap1D3Z4J11
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)Appl1 Dip13a Kiaa1428Q8K3H01
DCC-interacting protein 13-beta (Fragment)Appl2H3BL431
Dclk1 protein (Double cortin and calcium/calmodulin-dependent protein kinase-like 1, isoform CRA_d) (Putative uncharacterized protein) (Serine/threonine-protein kinase DCLK1)Dclk1 Dcamkl1 mCG_126612Q80VB61
DCN1-like protein 5 (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5)Dcun1d5Q9CXV91
DDB1 and CUL4-associated factor 4 (WD repeat domain 21)Dcaf4 Wdr21Q99LF71
DDRGK domain-containing protein 1 (UFM1-binding and PCI domain-containing protein 1)Ddrgk1 Ufbp1Q80WW91
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b (Putative uncharacterized protein)Ddx19bQ8BZY31
DEAH (Asp-Glu-Ala-His) box polypeptide 16 (DEAH (Asp-Glu-Ala-His) box polypeptide 16, isoform CRA_a)Dhx16 mCG_141148G3X8X01
DEAH (Asp-Glu-Ala-His) box polypeptide 16 (Dhx16 protein)Dhx16Q05BH31
DEAH (Asp-Glu-Ala-His) box polypeptide 37Dhx37Q6NZL11
DEAH (Asp-Glu-Ala-His) box polypeptide 38 (Putative uncharacterized protein)Dhx38Q80X981
Decapping and exoribonuclease protein (DXO) (EC 3.1.13.-) (EC 3.6.1.-) (Dom-3 homolog Z)Dxo Dom3z Ng6O703481
Dedicator of cytokinesis protein 3Dock3F8VPQ11
Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP)Dock3 MocaQ8CIQ71
Dedicator of cytokinesis protein 4Dock4 Kiaa0716P597641
Dedicator of cytokinesis protein 6Dock6 Kiaa1395Q8VDR91
Dedicator of cytokinesis protein 9Dock9E9QMR21
Dehydrodolichyl diphosphate synthase complex subunit Dhdds (Fragment)DhddsA3KGK91
Dehydrodolichyl diphosphate synthase complex subunit Nus1 (EC 2.5.1.87) (Di-trans,poly-cis-decaprenylcistransferase) (Nogo-B receptor) (NgBR) (Nuclear undecaprenyl pyrophosphate synthase 1 homolog)Nus1 D10Ertd438e NgbrQ99LJ81
Dehydrogenase/reductase SDR family member 13Dhrs13B0QZT21
Dehydrogenase/reductase SDR family member 13 (EC 1.1.-.-) (Short chain dehydrogenase/reductase family 7C member 5)Dhrs13 Sdr7c5Q5SS801
Deleted in malignant brain tumors 1 proteinDmbt1E9QPG81
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)Aldh4a1Q8CHT01
Delta-sarcoglycanSgcdA2ACH61
Dematin (Dematin actin-binding protein) (Erythrocyte membrane protein band 4.9)Dmtn Epb4.9 Epb49Q9WV691
DENN domain-containing protein 2CDennd2cQ6P9P81
DENN domain-containing protein 4CDennd4cE9Q4491
DENN domain-containing protein 5B (Rab6IP1-like protein)Dennd5bA2RSQ01
Density-regulated protein (Fragment)DenrE9Q0G11
Denticleless protein homolog (Lethal(2) denticleless protein homolog) (Meth A retinoic acid-regulated nuclear matrix-associated protein) (Meth A RAMP) (Retinoic acid-regulated nuclear matrix-associated protein)Dtl Cdt2 L2dtl RampQ3TLR71
Deoxyhypusine hydroxylaseDohhD3Z6Y91
Deoxyhypusine hydroxylase (Fragment)DohhD3Z7J71
Deoxyhypusine synthase (Fragment)DhpsF6W7I21
Deoxyribonuclease-2-alpha (EC 3.1.22.1) (Acid DNase) (Deoxyribonuclease II alpha) (DNase II alpha) (Lysosomal DNase II)Dnase2 Dnase2a Dnl2P565421
DEP domain-containing protein 1BDepdc1bE9PW091
Derlin-2 (Degradation in endoplasmic reticulum protein 2) (Der1-like protein 2) (F-LANa)Derl2 Der2 FlanaQ8BNI41
Dermatan-sulfate epimerase (DS epimerase) (EC 5.1.3.19) (Chondroitin-glucuronate 5-epimerase) (Squamous cell carcinoma antigen recognized by T-cells 2) (SART-2)Dse Sart2Q8BLI41
DermokineDmknE9Q2P11
Desmocollin-3Dsc3P558501
Desmoglein-2Dsg2O551111
Desmoglein-4Dsg4Q7TMD71
Developmental pluripotency-associated protein 5A (mDppa5) (ES cell-associated transcript 2 protein) (Embryonal stem cell-specific gene 1 protein) (ESG-1) (Protein pH 34)Dppa5a Dppa5 Ecat2 Esg1 Ph34Q9CQS71
Diacylglycerol kinase (DAG kinase) (EC 2.7.1.107)DgkzA2AHJ71
Diacylglycerol kinase (DAG kinase) (EC 2.7.1.107)Dgkz mCG_130421A2AHK01
Diacylglycerol kinase alpha (DAG kinase alpha) (EC 2.7.1.107) (80 kDa diacylglycerol kinase) (Diglyceride kinase alpha) (DGK-alpha)Dgka Dagk1O886731
Diacylglycerol kinase epsilonDgkeF2Z4901
Diacylglycerol kinase epsilon (DAG kinase epsilon) (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon)DgkeQ9R1C61
Differentially expressed in FDCP 6 (DEF-6) (IRF4-binding protein) (SWAP-70-like adapter of T-cells)Def6 Ibp SlatQ8C2K11
Differentially expressed in FDCP 8 (DEF-8)Def8 D8Ertd713eQ99J781
DiGeorge syndrome critical region gene 2 (DiGeorge syndrome critical region gene 2, isoform CRA_a) (Integral membrane protein DGCR2/IDD) (Putative uncharacterized protein)Dgcr2 mCG_131834Q6P5A91
Dihydroorotate dehydrogenase (quinone), mitochondrialDhodhE9Q1V31
Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)DhodhO354351
Dihydroorotate dehydrogenase (quinone), mitochondrial (Fragment)DhodhF6ZQJ51
Dihydropteridine reductase (Fragment)QdprD3Z1A11
Dihydropyrimidinase (DHP) (DHPase) (EC 3.5.2.2) (Dihydropyrimidine amidohydrolase) (Hydantoinase)DpysQ9EQF51
Dihydropyrimidinase-like 4 (Dihydropyrimidinase-related protein 4) (Putative uncharacterized protein)Dpysl4Q3TMU81
Dihydropyrimidinase-related protein 1 (Fragment)Crmp1A0A0J9YTX51
Dihydropyrimidinase-related protein 3Dpysl3E9PWE81
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