EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Dihydropyrimidinase-related protein 3 (Fragment)Dpysl3D3YUS01
Dihydropyrimidinase-related protein 4 (DRP-4) (Collapsin response mediator protein 3) (CRMP-3) (UNC33-like phosphoprotein 4) (ULIP-4)Dpysl4 Crmp3 Ulip4O350981
Dihydropyrimidinase-related protein 5 (DRP-5) (Collapsin response mediator protein 5) (CRMP-5)Dpysl5 Crmp5Q9EQF61
Dihydroxyacetone phosphate acyltransferase (DAP-AT) (DHAP-AT) (EC 2.3.1.42) (Acyl-CoA:dihydroxyacetonephosphateacyltransferase) (Glycerone-phosphate O-acyltransferase)Gnpat DhapatP981921
Dihydroxyacetone phosphate acyltransferase (Gnpat protein) (Fragment)GnpatQ05DV21
Dimethylarginine dimethylaminohydrolase 1, isoform CRA_a (N(G),N(G)-dimethylarginine dimethylaminohydrolase 1)Ddah1 mCG_7778D3YU151
Dimethylarginine dimethylaminohydrolase 2, isoform CRA_a (N(G),N(G)-dimethylarginine dimethylaminohydrolase 2) (Putative uncharacterized protein)Ddah2 mCG_15913O089721
Dipeptidyl aminopeptidase-like protein 6 (DPPX) (Dipeptidyl aminopeptidase-related protein) (Dipeptidyl peptidase 6) (Dipeptidyl peptidase IV-like protein) (Dipeptidyl peptidase VI) (DPP VI)Dpp6 Dpp-6Q9Z2181
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (muDIPP1) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3)Nudt3 Dipp Dipp1Q9JI461
Diphthine--ammonia ligase (EC 6.3.1.14) (ATP-binding domain-containing protein 4) (Diphthamide synthase) (Diphthamide synthetase) (Protein DPH6 homolog)Dph6 Atpbd4Q9CQ281
Disabled homolog 2Dab2E0CXT51
Disabled homolog 2Dab2E9QL311
Disabled homolog 2 (Fragment)Dab2F6TQN91
Disabled homolog 2 (Putative uncharacterized protein)Dab2Q9DCE61
Disabled homolog 2-interacting proteinDab2ipA2AUX31
Disabled homolog 2-interacting proteinDab2ipA2AUX51
Disabled homolog 2-interacting proteinDab2ipB7ZD291
Disabled homolog 2-interacting protein (DAB2-interacting protein) (ASK-interacting protein 1) (DOC-2/DAB-2 interactive protein)Dab2ip Kiaa1743Q3UHC71
Disabled homolog 2-interacting protein (Fragment)Dab2ipF6RK071
Disabled homolog 2-interacting protein (Fragment)Dab2ipF6QQP61
Disco-interacting protein 2 homolog ADip2aD3Z7D31
Disintegrin and metalloproteinase domain-containing protein 12 (Fragment)Adam12F6YWH61
Disintegrin and metalloproteinase domain-containing protein 19 (ADAM 19) (EC 3.4.24.-) (Meltrin-beta)Adam19 MltnbO356741
Disintegrin and metalloproteinase domain-containing protein 8 (ADAM 8) (EC 3.4.24.-) (Cell surface antigen MS2) (Macrophage cysteine-rich glycoprotein) (CD antigen CD156a)Adam8 Ms2Q059101
Disks large homolog 1Dlg1E9Q9H01
Disks large homolog 1Dlg1D3Z3B81
Disks large homolog 3 (Synapse-associated protein 102) (SAP-102) (SAP102)Dlg3 Dlgh3P701751
Disks large-associated protein 4Dlgap4I1E4X01
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)Dlgap4 Kiaa0964 Sapap4B1AZP21
Disks large-associated protein 4 (Dlgap4 protein)Dlgap4B7ZNS21
Disks large-associated protein 5 (DAP-5) (Discs large homolog 7) (Disks large-associated protein DLG7) (Hepatoma up-regulated protein homolog) (HURP)Dlgap5 Dlg7 Kiaa0008Q8K4R91
Disrupted in renal carcinoma protein 2 homologDirc2Q8BFQ61
Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) (EC 2.5.1.87)DhddsA3KGL01
Ditrans,polycis-polyprenyl diphosphate synthase ((2E,6E)-farnesyl diphosphate specific) (EC 2.5.1.87) (Fragment)DhddsA3KGL31
DmX-like protein 2Dmxl2B0V2P51
DNA (cytosine-5)-methyltransferase (EC 2.1.1.37)Dnmt1J3QNW01
DNA (cytosine-5)-methyltransferase 3-likeDnmt3lQ9CWR81
DNA (cytosine-5)-methyltransferase 3A (Fragment)Dnmt3aG3UXY21
DNA damage-inducible transcript 3 protein (DDIT-3) (C/EBP zeta) (C/EBP-homologous protein) (CHOP) (C/EBP-homologous protein 10) (CHOP-10) (CCAAT/enhancer-binding protein homologous protein) (Growth arrest and DNA-damage-inducible protein GADD153)Ddit3 Chop Chop10 Gadd153P356391
DNA damage-regulated autophagy modulator protein 2 (Fragment)Dram2D3Z6B71
DNA dC->dU-editing enzyme APOBEC-3Apobec3H3BJQ31
DNA ligase (EC 6.5.1.1)Lig3 mCG_8187B1AT031
DNA ligase (EC 6.5.1.1)Lig3K4DI591
DNA ligase (EC 6.5.1.1)Lig3Q3UC821
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)Mlh1Q9JK911
DNA nucleotidylexotransferase (EC 2.7.7.31) (Terminal addition enzyme) (Terminal deoxynucleotidyltransferase) (TDT) (Terminal transferase)Dntt TdtP098381
DNA polymerase delta subunit 3 (DNA polymerase delta subunit p66)Pold3Q9EQ281
DNA polymerase delta subunit 3 (Polymerase (DNA-directed), delta 3, accessory subunit) (Putative uncharacterized protein)Pold3Q8BH761
DNA polymerase eta (EC 2.7.7.7) (RAD30 homolog A) (Xeroderma pigmentosum variant type protein homolog)Polh Rad30a XpvQ9JJN01
DNA primase (EC 2.7.7.-)Prim1J3QN191
DNA repair and recombination protein RAD54-like (EC 3.6.4.-) (RAD54 homolog) (mHR54) (mRAD54)Rad54l Rad54P702701
DNA repair protein RAD51 homolog 1Rad51D6RCK11
DNA repair protein RAD51 homolog 1 (RAD51 homolog A)Rad51 Rad51a RecaQ082971
DNA replication licensing factor MCM7Mcm7D3Z6N31
DNA segment, Chr 2, ERATO Doi 750, expressed, isoform CRA_c (Small kinetochore-associated protein) (Fragment)Knstrn D2Ertd750e mCG_6532A3KGG61
DNA segment, Chr 6, Wayne State University 176, expressed, isoform CRA_a (Protein FAM3C)Fam3c D6Wsu176e mCG_9383G3X9I11
DNA topoisomerase (EC 5.99.1.2) (Fragment)Top3bD3Z0841
DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (Fragment)Apex1D3Z1241
DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (Fragment)Apex1F6QA741
DNA-binding protein RFX8 (Regulatory factor X 8)Rfx8D3YU811
DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1)Satb1Q606111
DNA-binding protein SMUBP-2 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase IGHMBP2) (Cardiac transcription factor 1) (CATF1) (Immunoglobulin mu-binding protein 2)Ighmbp2 Smbp-2 Smbp2P406941
DNA-directed RNA polymerase (EC 2.7.7.6)PolrmtE9PWD91
DNA-directed RNA polymerase I subunit RPA2Polr1bA2AP841
DNA-directed RNA polymerase II subunit RPB11 (Polymerase (RNA) II (DNA directed) polypeptide J)Polr2j mCG_1879Q6PI631
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31)Polr2c Rpo2-3Q99M461
DNA-directed RNA polymerase subunit (EC 2.7.7.6)Polr2aA0A0R4J0V51
DNA-directed RNA polymerase, mitochondrial (MtRPOL) (EC 2.7.7.6)PolrmtQ8BKF11
DNA-directed RNA polymerases I and III subunit RPAC1Polr1cD3Z3D61
DNA-directed RNA polymerases I and III subunit RPAC1 (Fragment)Polr1cD3Z7Q81
DnaJ (Hsp40) homolog, subfamily B, member 12, isoform CRA_d (DnaJ homolog subfamily B member 12) (Putative uncharacterized protein)Dnajb12 mCG_11302Q8C4C91
DnaJ (Hsp40) homolog, subfamily C, member 19, isoform CRA_c (Mitochondrial import inner membrane translocase subunit TIM14)Dnajc19 mCG_15246G3X8S11
DnaJ (Hsp40) homolog, subfamily C, member 5, isoform CRA_b (DnaJ homolog subfamily C member 5)Dnajc5 mCG_23060G5E8T01
DnaJ heat shock protein family (Hsp40) member C13 (Receptor mediated endocytosis-8)Dnajc13 RME-8D4AFX71
DnaJ homolog subfamily B member 12 (mDj10)Dnajb12Q9QYI41
DnaJ homolog subfamily B member 6 (Fragment)Dnajb6F6YRQ21
DnaJ homolog subfamily C member 11Dnajc11E9Q8B31
DnaJ homolog subfamily C member 15Dnajc15 Dnajd1Q78YY61
DnaJ homolog subfamily C member 2Dnajc2E9Q9H31
DnaJ homolog subfamily C member 8Dnajc8A2ALF01
DnaJ homolog subfamily C member 8Dnajc8A2ALF31
DnaJ homolog subfamily C member 8 (Fragment)Dnajc8F6TQL31
Dock10 proteinDock10B2RWY01
Dolichol-phosphate mannosyltransferase subunit 1Dpm1A2BDX21
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3BStt3bA0A0R4J0D31
Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog)Alg5Q9DB251
Double-stranded RNA-binding protein Staufen homolog 1Stau1A2A5S31
Double-stranded RNA-binding protein Staufen homolog 1Stau1V9GX871
Double-stranded RNA-binding protein Staufen homolog 1 (Putative uncharacterized protein) (Staufen (RNA binding protein) homolog 1 (Drosophila)) (Staufen (RNA binding protein) homolog 1 (Drosophila), isoform CRA_a) (Staufen isoform I2)Stau1 mCG_14603Q9DBE71
Double-stranded RNA-binding protein Staufen homolog 2Stau2Q8CJ671
Dual specificity phosphatase 19 (Dual specificity phosphatase 19, isoform CRA_a) (Dual-specificity phosphatase TS-DSP1) (Dual-specificity protein phosphatase 19) (Protein phosphatase) (Putative uncharacterized protein)Dusp19 mCG_11093Q99N121
Dual specificity phosphatase 22, isoform CRA_b (Dual-specificity protein phosphatase 22)Dusp22 mCG_4920Z4YL331
Dual specificity protein kinase CLK4 (EC 2.7.12.1) (CDC-like kinase 4)Clk4O354931
Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT)Ttk EskP357611
Dual specificity protein phosphatase 1 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 1) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP)Dusp1 3ch134 Mkp1 Ptpn10 Ptpn16P285631
Dual specificity protein phosphatase 13 isoform A (DUSP13A) (EC 3.1.3.16) (EC 3.1.3.48) (Muscle-restricted DSP)Dusp13 Dusp13a MdspQ6B8I01
Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1)Dusp19 Skrp1Q8K4T51
Dual-specificity mitogen-activated protein kinase kinase 6Map2k6A2AGS21
Dual-specificity protein phosphatase 3Dusp3B1AQF41
Dual-specificity protein phosphatase 3Dusp3H3BKL81
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