EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Dynactin subunit 1Dctn1E9Q3M31
Dynactin subunit 1Dctn1D3YX341
Dynamin-1Dnm1A0A0J9YUE91
Dynamin-2Dnm2G3X9G41
Dynamin-like 120 kDa protein, mitochondrialOpa1H7BX011
Dynamin-like 120 kDa protein, mitochondrial (Fragment)Opa1F6U7751
Dynein heavy chain 12, axonemal (Axonemal beta dynein heavy chain 12) (Axonemal dynein heavy chain 12-like protein) (Axonemal dynein heavy chain 7-like protein) (Ciliary dynein heavy chain 12)Dnah12 Dnah12l Dnah7l Dnahc12 Dnahc7lQ3V0Q11
Dynein heavy chain 17, axonemal (Axonemal beta dynein heavy chain 17) (Ciliary dynein heavy chain 17)Dnah17 Dnahc17 Kiaa3028Q69Z231
Dynein heavy chain domain 1 (Mitochondrial import inner membrane translocase subunit Tim10 B)Timm10b Dnhd1 Fxc1D6RG991
Dynein light chain 2, cytoplasmicDynll2D6RIN41
Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like)Dynlt3 Tcte1lP563871
Dynein, axonemal, heavy chain 10Dnah10 Dnahc10D3YYQ81
Dynein, axonemal, heavy chain 11Dnah11 Dnahc11E9Q7N91
DystoninDstE9Q9X11
Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2)Dst Bpag1 Macf2E9PXE51
Dystonin (Bullous pemphigoid antigen 1) (BPA) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) (Microtubule actin cross-linking factor 2)Dst Bpag1 Macf2E9QL231
DystrobrevinDtnbG3UYM71
DystrobrevinDtnbG3UZ871
DystrobrevinDtnbQ8C8Z91
DystrobrevinDtnaQ8CFR51
DystrobrevinDtnbQ8K0N01
Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin)Dtna DtnQ9D2N41
Dystrophin (Dystrophin 71)DmdA2A9Z21
Dystrophin (Dystrophin Dp71a)DmdA2A9Z11
E3 ubiquitin-protein ligase ARIH1Arih1H7BWY71
E3 ubiquitin-protein ligase ARIH1Arih1H9KV211
E3 ubiquitin-protein ligase CBLCblA0A0X1KG611
E3 ubiquitin-protein ligase DTX4 (EC 2.3.2.27) (Protein deltex-4) (Deltex4) (RING-type E3 ubiquitin transferase DTX4)Dtx4Q6PDK81
E3 ubiquitin-protein ligase DZIP3Dzip3E9QNZ21
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3 homolog) (RING-type E3 ubiquitin transferase DZIP3)Dzip3 Kiaa0675Q7TPV21
E3 ubiquitin-protein ligase FANCL (EC 2.3.2.27) (Fanconi anemia group L protein homolog) (Proliferation of germ cells protein) (RING-type E3 ubiquitin transferase FANCL)Fancl Phf9 PogQ9CR141
E3 ubiquitin-protein ligase LRSAM1 (EC 2.3.2.27) (Leucine-rich repeat and sterile alpha motif-containing protein 1) (RING-type E3 ubiquitin transferase LRSAM1) (Tsg101-associated ligase)Lrsam1Q80ZI61
E3 ubiquitin-protein ligase MARCH5 (EC 2.3.2.27) (Membrane-associated RING finger protein 5) (Membrane-associated RING-CH protein V) (MARCH-V) (RING-type E3 ubiquitin transferase MARCH5)March5Q3KNM21
E3 ubiquitin-protein ligase MARCH5 (MCG13921, isoform CRA_c)March5 mCG_13921A0A0R4J1H01
E3 ubiquitin-protein ligase MARCH8 (EC 2.3.2.27) (Cellular modulator of immune recognition) (c-MIR) (Membrane-associated RING finger protein 8) (Membrane-associated RING-CH protein VIII) (MARCH-VIII) (RING-type E3 ubiquitin transferase MARCH8)March8 MirQ9DBD21
E3 ubiquitin-protein ligase Midline-1 (EC 2.3.2.27) (Midin) (RING finger protein Midline-1) (RING-type E3 ubiquitin transferase Midline-1) (Tripartite motif-containing protein 18)Mid1 Fxy Trim18O705831
E3 ubiquitin-protein ligase MYCBP2Mycbp2E9PUJ61
E3 ubiquitin-protein ligase MYCBP2 (Fragment)Mycbp2F6SMY71
E3 ubiquitin-protein ligase MYCBP2 (Fragment)Mycbp2F6T4V91
E3 ubiquitin-protein ligase NRDP1 (EC 2.3.2.27) (RING finger protein 41) (RING-type E3 ubiquitin transferase NRDP1)Rnf41 Flrf Nrdp1Q8BH751
E3 ubiquitin-protein ligase Praja-1 (Praja1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Praja-1)Pja1O551761
E3 ubiquitin-protein ligase RAD18Rad18D3Z7331
E3 ubiquitin-protein ligase RAD18Rad18D3Z7341
E3 ubiquitin-protein ligase RAD18Rad18E9Q3921
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (mRAD18Sc) (RING-type E3 ubiquitin transferase RAD18)Rad18 Rad18scQ9QXK21
E3 ubiquitin-protein ligase RAD18 (RAD18 homolog (S. cerevisiae), isoform CRA_d)Rad18 mCG_128966W4VSP91
E3 ubiquitin-protein ligase RLIM (EC 2.3.2.27) (LIM domain-interacting RING finger protein) (RING finger LIM domain-binding protein) (R-LIM) (RING finger protein 12) (RING-type E3 ubiquitin transferase RLIM)Rlim Rnf12Q9WTV71
E3 ubiquitin-protein ligase RNF115 (EC 2.3.2.27) (RING finger protein 115) (RING-type E3 ubiquitin transferase RNF115) (Rabring 7) (Zinc finger protein 364)Rnf115 Zfp364 Znf364Q9D0C11
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)Rnf138 TrifQ9CQE01
E3 ubiquitin-protein ligase RNF14 (EC 2.3.2.-) (Androgen receptor-associated protein 54) (Protein Triad2) (RING finger protein 14)Rnf14 Ara54 Triad2Q9JI901
E3 ubiquitin-protein ligase RNF169 (EC 2.3.2.27) (RING finger protein 169) (RING-type E3 ubiquitin transferase RNF169)Rnf169 Kiaa1991E9Q7F21
E3 ubiquitin-protein ligase RNF182 (EC 2.3.2.27) (RING finger protein 182) (RING-type E3 ubiquitin transferase RNF182)Rnf182Q8C4321
E3 ubiquitin-protein ligase RNF213 (EC 2.3.2.27) (EC 3.6.4.-) (Mysterin) (RING finger protein 213) (RING-type E3 ubiquitin transferase RNF213)Rnf213 MystrF7A6H41
E3 ubiquitin-protein ligase RNF25Rnf25E9Q4461
E3 ubiquitin-protein ligase RNF25 (EC 2.3.2.27) (RING finger protein 25) (RING finger protein AO7) (RING-type E3 ubiquitin transferase RNF25)Rnf25Q9QZR01
E3 ubiquitin-protein ligase SH3RF1Sh3rf1E9QQ331
E3 ubiquitin-protein ligase SH3RF1 (EC 2.3.2.27) (Plenty of SH3s) (Protein POSH) (RING-type E3 ubiquitin transferase SH3RF1) (SH3 domain-containing RING finger protein 1) (SH3 multiple domains protein 2)Sh3rf1 Kiaa1494 Posh Sh3md2Q69ZI11
E3 ubiquitin-protein ligase SMURF1Smurf1E9PYU81
E3 ubiquitin-protein ligase synoviolinSyvn1D3Z1Y11
E3 ubiquitin-protein ligase synoviolinSyvn1E9QQ991
E3 ubiquitin-protein ligase synoviolin (EC 2.3.2.27) (RING-type E3 ubiquitin transferase synoviolin) (Synovial apoptosis inhibitor 1)Syvn1 Hrd1 Kiaa1810Q9DBY11
E3 ubiquitin-protein ligase TRAIP (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRAIP) (TRAF-interacting protein)Traip TripQ8VIG61
E3 ubiquitin-protein ligase TRIM33Trim33E9QME51
E3 ubiquitin-protein ligase TRIM33Trim33E9QP191
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)Trim37 Kiaa0898Q6PCX91
E3 ubiquitin-protein ligase TRIM41 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM41) (Tripartite motif-containing protein 41)Trim41Q5NCC31
E3 ubiquitin-protein ligase TRIM56Trim56A0A0R4J0Q61
E3 ubiquitin-protein ligase TRIM63Trim63A2A9L41
E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (mLin41) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71)Trim71 Gm1127 Lin41Q1PSW81
E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Mtprd)Ttc3 Kiaa4119O881961
E3 ubiquitin-protein ligase TTC3 (Tetratricopeptide repeat domain 3, isoform CRA_b)Ttc3 mCG_19601G5E8T21
E3 ubiquitin-protein ligase UBR1 (EC 2.3.2.27) (N-recognin-1) (RING-type E3 ubiquitin transferase UBR1) (Ubiquitin-protein ligase E3-alpha-1) (Ubiquitin-protein ligase E3-alpha-I)Ubr1O704811
E3 ubiquitin-protein ligase UBR5Ubr5E9Q2H11
E3 ubiquitin-protein ligase ZNRF1 (EC 2.3.2.27) (Nerve injury-induced gene 283 protein) (RING-type E3 ubiquitin transferase ZNRF1) (Zinc/RING finger protein 1)Znrf1 Nin283Q91V171
E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2)Znrf2Q71FD51
E3 UFM1-protein ligase 1 (EC 6.3.2.-)Ufl1 Kiaa0776Q8CCJ31
Ectonucleoside triphosphate diphosphohydrolase 2 (Ectonucleoside triphosphate diphosphohydrolase 2, isoform CRA_b)Entpd2 mCG_20290Q921R11
Ectonucleoside triphosphate diphosphohydrolase 6 (Ectonucleoside triphosphate diphosphohydrolase 6, isoform CRA_a) (Putative uncharacterized protein)Entpd6 mCG_16316Q3U0P51
Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7) (EC 3.6.1.-) (Lysosomal apyrase-like protein 1)Entpd7 Kiaa4066 Lalp1Q3TCT41
Ectonucleotide pyrophosphatase/phosphodiesterase 1, isoform CRA_d (Ectonucleotide pyrophosphatase/phosphodiesterase family member 1)Enpp1 mCG_9001G3X9S21
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (E-NPP 5) (NPP-5) (EC 3.1.-.-)Enpp5Q9EQG71
Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (E-NPP 6) (NPP-6) (EC 3.1.4.-) (EC 3.1.4.38) (Choline-specific glycerophosphodiester phosphodiesterase) (Glycerophosphocholine cholinephosphodiesterase) (GPC-Cpde)Enpp6Q8BGN31
Eef1d protein (Elongation factor 1-delta) (MCG22130, isoform CRA_b)Eef1d mCG_22130Q91VK21
EF-hand calcium-binding domain-containing protein 14Efcab14 Kiaa0494Q8BGQ61
EF-hand calcium-binding domain-containing protein 14Efcab14 4732418C07RikA2A8T91
EF-hand calcium-binding domain-containing protein 14Efcab14 4732418C07RikQ6PCQ61
EF-hand calcium-binding domain-containing protein 6 (DJ-1-binding protein) (DJBP)Efcab6 Djbp Kiaa1672Q6P1E81
EF-hand calcium-binding domain-containing protein 7Efcab7 Kiaa1799Q8VDY41
EF-hand calcium-binding domain-containing protein 7Efcab7F6XAI71
EF-hand domain-containing family member BEfhbQ8CDU51
EF-hand domain-containing protein D2 (Swiprosin-1)Efhd2 Sws1Q9D8Y01
EH domain-binding protein 1-like protein 1 (RIKEN cDNA G430002G23, isoform CRA_a)Ehbp1l1 G430002G23Rik mCG_11792G5E8Y61
eIF-2-alpha kinase GCN2Eif2ak4A2AUM01
eIF-2-alpha kinase GCN2Eif2ak4A2AUM11
eIF-2-alpha kinase GCN2Eif2ak4A2AUM21
eIF-2-alpha kinase GCN2 (Eukaryotic translation initiation factor 2-alpha kinase 4) (EC 2.7.11.1) (GCN2-like protein) (mGCN2)Eif2ak4 Gcn2 Kiaa1338Q9QZ051
ELAV-like protein 3 (Hu-antigen C) (HuC)Elavl3 HucQ609001
ELKS/Rab6-interacting/CAST family member 1Erc1V9GWT61
ELKS/Rab6-interacting/CAST family member 1Erc1V9GXH31
ELKS/Rab6-interacting/CAST family member 1 (Rab6 interacting protein 2, isoform CRA_a)Erc1 Rab6ip2 mCG_131716V9GXF01
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