EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Kinetochore protein Spc25 (Fragment)Spc25A2AUT11
Kinetochore protein Spc25 (Fragment)Spc25A2AUT31
Kinetochore protein Spc25 (Fragment)Spc25A2AUT41
Kinetochore-associated protein DSN1 homologDsn1Q9CYC51
KN motif and ankyrin repeat domains 1 (Fragment)Kank1E9Q9441
KRR1 small subunit processome component homologKrr1G3UZA01
Krt6b proteinKrt6bQ0VDR71
Krueppel-like factor 13 (Basic transcription element-binding protein 3) (BTE-binding protein 3) (Erythroid transcription factor FKLF-2) (RANTES factor of late activated T-lymphocytes 1) (RFLAT-1) (Transcription factor BTEB3)Klf13 Bteb3 Fklf2Q9JJZ61
Kunitz-type protease inhibitor 1 (Hepatocyte growth factor activator inhibitor type 1) (HAI-1)Spint1 Hai1Q9R0971
L-2-hydroxyglutarate dehydrogenase, mitochondrial (EC 1.1.99.2) (Duranin)L2hgdhQ91YP01
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (EC 2.7.8.-) (4'-phosphopantetheinyl transferase) (Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase) (AASD-PPT)AasdhpptQ9CQF61
L-lactate dehydrogenase (EC 1.1.1.27)Ldha Ldh1 mCG_19938G5E8N51
L-lactate dehydrogenase (EC 1.1.1.27)Ldha mCG_19938A0A1B0GSX01
L-threonine aldolase (Threonine aldolase 1)Tha1 Gly1Q6XPS71
L-xylulose reductase (XR) (EC 1.1.1.10) (Dicarbonyl/L-xylulose reductase)DcxrQ91X521
La-related protein 4 (MCG123519)Larp4 mCG_123519G3X9Q61
Lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.99.9) (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase) (Ganglioside GM3 synthase) (ST3Gal V) (ST3GalV) (Sialyltransferase 9)St3gal5 GM3S Siat9O888291
Lamin-B2Lmnb2P216191
Large proline-rich protein BAG6Bag6G3UYQ21
Large proline-rich protein BAG6Bag6G3UZT61
Large proline-rich protein BAG6 (Fragment)Bag6G3UXT81
Large subunit GTPase 1 homolog (Fragment)Lsg1F7AMG01
Lariat debranching enzyme (EC 3.1.-.-)Dbr1Q923B11
Latent-transforming growth factor beta-binding protein 1 (Fragment)Ltbp1B1B1E21
Latent-transforming growth factor beta-binding protein 2 (LTBP-2)Ltbp2O089991
LDLR chaperone MESD (Fragment)Mesdc2D3YVR41
Lectin, mannose-binding 2-like, isoform CRA_b (VIP36-like protein)Lman2l mCG_17749D3Z4P21
Left-right determination factor 1 (Protein lefty-1) (Lefty protein) (Stimulated by retinoic acid gene 3 protein) (Transforming growth factor beta-4) (TGF-beta-4)Lefty1 Ebaf Lefty Stra3 Tgfb4Q642801
LEM domain-containing protein 2 (Nuclear envelope transmembrane protein 25) (NET25)Lemd2 Lem2Q6DVA01
Leptin receptor gene-related protein (Endospanin-1) (OB-R gene-related protein) (OB-RGRP)Leprot Lepr ObrO890131
Lethal(2) giant larvae protein homolog 1Llgl1A0A0R4J0S41
Lethal(2) giant larvae protein homolog 2Llgl2J3QJU51
Leucine rich repeat containing 1, isoform CRA_b (Leucine-rich repeat-containing protein 1)Lrrc1 mCG_14390G3X9W31
Leucine zipper protein 4Luzp4B1AV091
Leucine zipper protein 4Luzp4L7N2781
Leucine-rich repeat and calponin homology domain-containing protein 3Lrch3E9QAU91
Leucine-rich repeat and WD repeat-containing protein 1 (ORC-associated protein) (ORCA) (Origin recognition complex-associated protein)LRWD1 OrcaQ8BUI31
Leucine-rich repeat flightless-interacting protein 2Lrrfip2E9QN521
Leucine-rich repeat flightless-interacting protein 2Lrrfip2A0A0R4J1691
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)Lrrfip2Q91WK01
Leucine-rich repeat neuronal protein 1 (Neuronal leucine-rich repeat protein 1) (NLRR-1)Lrrn1 Kiaa1497Q618091
Leucine-rich repeat serine/threonine-protein kinase 1 (EC 2.7.11.1)Lrrk1 Kiaa1790Q3UHC21
Leucine-rich repeat transmembrane protein FLRT2 (Fibronectin leucine rich transmembrane protein 2)Flrt2 Kiaa0405Q8BLU01
Leucine-rich repeat-containing protein 14Lrrc14 Kiaa0014Q8VC161
Leucine-rich repeat-containing protein 15Lrrc15Q80X721
Leucine-rich repeat-containing protein 2Lrrc2A0A0R4J0F21
Leucine-rich repeat-containing protein 25 (Monocyte and plasmacytoid-activated protein)Lrrc25 MapaQ8K1T11
Leucine-rich repeat-containing protein 45Lrrc45Q8CIM11
Leucine-rich repeat-containing protein 57Lrrc57Q9D1G51
Leucine-rich repeat-containing protein 7Lrrc7E9Q6L91
Leucine-rich repeats and immunoglobulin-like domains protein 2 (LIG-2)Lrig2 Kiaa0806Q52KR21
Leucine-zipper-like transcriptional regulator 1 (Fragment)Lztr1F6VJI51
Leukemia inhibitory factor (LIF) (Differentiation-stimulating factor) (D factor)LifP090561
Leukocyte immunoglobulin-like receptor subfamily B member 3 (LIR-3) (Leukocyte immunoglobulin-like receptor 3) (Cell-surface glycoprotein p91) (Paired immunoglobulin-like receptor B) (PIR-B)Lilrb3 PirbP974841
Leukocyte receptor cluster member 1 homologLeng1Q9DB981
Leukocyte surface antigen CD47Cd47D3Z1871
Ligand of Numb protein X 2 (Numb-binding protein 2)Lnx2Q91XL21
LIM and calponin homology domains-containing protein 1Limch1 Kiaa1102Q3UH681
LIM and senescent cell antigen-like-containing domain protein 2 (Particularly interesting new Cys-His protein 2) (PINCH-2)Lims2 Pinch2Q91XD21
LIM and SH3 domain protein 1 (Fragment)Lasp1A2A6G91
LIM and SH3 domain protein 1 (Fragment)Lasp1A2A6H01
LIM and SH3 domain protein 1 (Fragment)Lasp1A2A6G61
LIM and SH3 domain protein 1 (Fragment)Lasp1A2A6G71
LIM and SH3 domain protein 1 (Fragment)Lasp1A2A6G81
LIM domain kinase 1Limk1E9PVB61
LIM domain kinase 1 (LIMK-1) (EC 2.7.11.1) (KIZ-1)Limk1 LimkP536681
LIM domain-containing protein ajubaAjuba JubQ91XC01
LIM/homeobox protein Lhx2 (Homeobox protein LH-2) (LIM homeobox protein 2)Lhx2Q9Z0S21
LINE-1 type transposase domain-containing protein 1 (ES cell-associated protein 11)L1td1 Ecat11Q587J61
Lipase maturation factorLmf1Z4YJR11
Lipase member K (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 2)Lipk Lipl2Q8BM141
Lipid droplet-associated hydrolase (EC 3.1.1.-) (Lipid droplet-associated serine hydrolase) (mLDAH)LdahQ8BVA51
Lipoma HMGIC fusion partner-like 2 protein (Fragment)Lhfpl2D3Z6981
Lipopolysaccharide-responsive and beige-like anchor proteinLrbaE9Q3Y41
Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein)Lrba Bgl LbaQ9ESE11
Lipoprotein lipase (LPL) (EC 3.1.1.34)LplQ3U5U01
Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2)Ppfia2Q8BSS91
Liprin-beta-1 (Fragment)Ppfibp1F6YZ951
LOC435565 proteinIigp1b LOC435565Q8K2V41
LOC72520 protein (Fragment)LOC72520Q811J21
Lon protease homolog 2, peroxisomal (Putative uncharacterized protein)Lonp2Q8BK801
Lon protease homolog, mitochondrial (EC 3.4.21.-) (Lon protease-like protein) (LONP) (Mitochondrial ATP-dependent protease Lon) (Serine protease 15)Lonp1 LONP1 Prss15Q3V2D01
Long-chain fatty acid transport protein 1 (FATP-1) (Fatty acid transport protein 1) (EC 6.2.1.-) (Solute carrier family 27 member 1)Slc27a1 Fatp Fatp1Q607141
Long-chain fatty acid transport protein 4 (FATP-4) (Fatty acid transport protein 4) (EC 6.2.1.-) (Solute carrier family 27 member 4)Slc27a4 Acsvl4 Fatp4Q91VE01
Low density lipoprotein receptor adapter protein 1 (Autosomal recessive hypercholesterolemia protein homolog)Ldlrap1 ArhQ8C1421
Low-density lipoprotein receptor-related protein 12 (LRP-12)Lrp12Q8BUJ91
Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)Lrp1b LrpditQ9JI181
Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan)Lrp4 Kiaa0816Q8VI561
Low-density lipoprotein receptor-related protein 5Lrp5H3BL521
Low-density lipoprotein receptor-related protein 8Lrp8B1AXJ31
Low-density lipoprotein receptor-related protein 8Lrp8B1AXJ41
Low-density lipoprotein receptor-related protein 8Lrp8B1AXJ51
Low-density lipoprotein receptor-related protein 8Lrp8B1AXJ61
Low-density lipoprotein receptor-related protein 8 (Fragment)Lrp8F6YZZ81
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)Lrp8 Apoer2Q924X61
LRP2-binding proteinLrp2bpQ9D4C61
Luc7l2 protein (Putative RNA-binding protein Luc7-like 2)Luc7l2Q05CX51
Lunapark, ER junction formation factor (Fragment)Lnpk Lnp Lnpk1A2ASM01
Lung adenoma susceptibility protein 2Las2Q8CB141
Lymphocyte antigen 6D (Ly-6D) (Thymocyte B-cell antigen) (ThB)Ly6d Ly61 ThbP354591
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