EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Lymphocyte antigen 6E (Ly-6E) (Stem cell antigen 2) (Thymic shared antigen 1) (TSA-1)Ly6e Ly67 Sca-2 Tsa-1Q642531
Lymphocyte-specific protein 1Lsp1A2A6J41
Lymphoid enhancer-binding factor 1 (LEF-1)Lef1 Lef-1P277821
Lysine-specific demethylase 2A (Fragment)Kdm2aH3BL821
Lysine-specific demethylase 6B (EC 1.14.11.-) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3)Kdm6b Jmjd3 Kiaa0346Q5NCY01
Lysine-specific histone demethylase 1A (Fragment)Kdm1aF6Z4I31
Lysine-specific histone demethylase 1A (Fragment)Kdm1aG8JL401
LysM and putative peptidoglycan-binding domain-containing protein 2Lysmd2Q9D7V21
Lysophosphatidylcholine acyltransferase 1 (LPC acyltransferase 1) (LPCAT-1) (LysoPC acyltransferase 1) (mLPCAT1) (EC 2.3.1.23) (1-acylglycerophosphocholine O-acyltransferase) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 2)Lpcat1 Aytl2Q3TFD21
Lysophospholipase-like protein 1Lyplal1E9QLB21
Lysophospholipase-like protein 1 (EC 3.1.2.-)Lyplal1Q3UFF71
Lysosomal acid phosphatase (Fragment)Acp2B7ZCF41
Lysosomal alpha-glucosidaseGaaA2AFL31
Lysosomal alpha-glucosidase (Fragment)GaaF6R5R51
Lysosomal thioesterase PPT2 (Fragment)Ppt2E9Q0T01
Lysosomal thioesterase PPT2 (Fragment)Ppt2F6SPQ11
Lysosomal thioesterase PPT2 (Fragment)Ppt2G5E8W71
Lysosomal trafficking regulator, isoform CRA_a (Lysosomal-trafficking regulator)Lyst mCG_18823G5E8Q01
Lysosomal-associated transmembrane protein 5 (Fragment)Laptm5F6WX181
m-AAA protease-interacting protein 1, mitochondrial (Matrix AAA peptidase-interacting protein 1)Maip1Q8BHE81
M-phase phosphoprotein 6Mphosph6Q9D1Q11
Maestro heat-like repeat-containing protein family member 2B (HEAT repeat-containing protein 7B2) (Sperm PKA-interacting factor) (SPIF)Mroh2b Heatr7b2Q7M6Y61
Maged2 protein (Melanoma antigen, family D, 2) (Putative uncharacterized protein)Maged2Q9ER671
Magnesium transporter NIPA4 (Ichthyin) (NIPA-like protein 4) (Non-imprinted in Prader-Willi/Angelman syndrome region protein 4 homolog)Nipal4 Ichn Nipa4Q8BZF21
Magnesium transporter protein 1 (Fragment)Magt1F6WHL01
MAGUK p55 subfamily member 7Mpp7Q8BVD51
Major centromere autoantigen B (Centromere protein B) (CENP-B)Cenpb Cenp-bP277901
Major facilitator superfamily domain-containing protein 6Mfsd6D3Z1831
Major urinary protein 14 (Fragment)Mup14B8JI961
Malic enzymeMe1 Mod1Q921S31
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCT) (EC 2.3.1.39) (Mitochondrial malonyltransferase) ([Acyl-carrier-protein] malonyltransferase)Mcat MtQ8R3F51
Maltase-glucoamylase (Soluble maltase-glucoamylase) (EC 3.2.1.20) (EC 3.2.1.3) (Fragment)MgamQ6XK231
Mannose-P-dolichol utilization defect 1 proteinMpdu1E9PVP31
MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein)MbipQ99LQ11
MAP6 domain-containing protein 1 (21 kDa STOP-like protein) (SL21)Map6d1Q14BB91
MAP7 domain-containing protein 1Map7d1 Mtap7d1A2AJI11
MAP7 domain-containing protein 1Map7d1 Mtap7d1A8Y5P41
MAP7 domain-containing protein 1 (Fragment)Map7d1 Mtap7d1F6WF361
MAPK-interacting and spindle-stabilizing protein-like (Mitogen-activated protein kinase 1-interacting protein 1-like)Mapk1ip1lQ8BH931
Matrilin-4 (MAT-4)Matn4O890291
Matrin-3 (Fragment)Matr3A0A087WNP31
Matrix metalloproteinase-17 (MMP-17) (EC 3.4.24.-) (Membrane-type matrix metalloproteinase 4) (MT-MMP 4) (MTMMP4) (Membrane-type-4 matrix metalloproteinase) (MT4-MMP) (MT4MMP)Mmp17 Mt4mmpQ9R0S31
Matrix-remodeling-associated protein 7 (Putative uncharacterized protein)Mxra7Q9D1T21
MCG1032217 (MCG131170) (Putative uncharacterized protein) (Ubiquitin-conjugating enzyme E2L 3)Ube2l3 mCG_1032217 mCG_131170Q561N41
MCG10343, isoform CRA_b (Phosphate carrier protein, mitochondrial)Slc25a3 mCG_10343G5E9021
MCG1051009 (Serine protease inhibitor A3K)Serpina3k mCG_1051009A0A0R4J0I11
MCG11560 (Putative uncharacterized protein)Slc25a5 mCG_11560Q545A21
MCG116540, isoform CRA_b (Ras association (RalGDS/AF-6) and pleckstrin homology domains 1)Raph1 mCG_116540G5E8671
MCG129810, isoform CRA_c (Pyridoxal-dependent decarboxylase domain-containing protein 1)Pdxdc1 mCG_129810A0A0R4J0341
MCG130893 (Zinc finger and BTB domain-containing 11)Zbtb11 mCG_130893G5E8B91
MCG133388, isoform CRA_n (Protocadherin gamma B6) (Protocadherin gamma subfamily B, 6)Pcdhgb6 mCG_133388Q91XX41
MCG13402, isoform CRA_d (Polypyrimidine tract-binding protein 1) (Putative uncharacterized protein)Ptbp1 mCG_13402Q8CB581
MCG140213Gm11596 mCG_140213B1AQB01
MCG140217Gm11564 mCG_140217A2A4L91
MCG1407, isoform CRA_a (Ribosome production factor 2 homolog)Rpf2 mCG_1407G3X9261
MCG141291 (Protocadherin beta 16)Pcdhb16 mCG_141291Q91Y031
MCG14171, isoform CRA_b (Microtubule-associated proteins 1A/1B light chain 3B)Map1lc3b mCG_14171M0QWC21
MCG142017, isoform CRA_a (Transmembrane and TPR repeat-containing protein 3)Tmtc3 mCG_142017G5E8C41
MCG14253, isoform CRA_a (Protein Wiz)Wiz mCG_14253G5E8J81
MCG14259, isoform CRA_b (Splicing factor U2AF 35 kDa subunit)U2af1 mCG_14259G3UW941
MCG15559Gm5814 mCG_15559J3QP801
MCG16669, isoform CRA_f (Putative uncharacterized protein) (TAR DNA-binding protein 43) (TARDBP S7) (TDP-43 variant 5)Tardbp TARDBP mCG_16669Q8BLD41
MCG16685, isoform CRA_d (Pre-mRNA-splicing regulator WTAP)Wtap mCG_16685E0CYH01
MCG16980, isoform CRA_b (Protein lin-7 homolog A) (Putative uncharacterized protein)Lin7a mCG_16980Q3TUM01
MCG18019 (VGF nerve growth factor inducible) (VGF nerve growth factor-inducible)Vgf mCG_18019Q0VGU41
MCG20113, isoform CRA_e (Myeloma overexpressed 2)Cops9 Myeov2 mCG_20113B2RVT11
MCG20149, isoform CRA_a (Methyltransferase like 7A1) (Methyltransferase-like 7A1) (Putative uncharacterized protein)Mettl7a1 Mettl7a mCG_20149Q8C6B01
MCG21910Gm12355 mCG_21910A2A4X61
MCG22048, isoform CRA_a (Proteasome activator complex subunit 2)Psme2 mCG_22048G3X9V01
MCG23377, isoform CRA_b (MCG54232) (Predicted pseudogene 8797)Gm8797 mCG_23377 mCG_54232A0A0A6YW671
MCG2960, isoform CRA_a (Metalloreductase STEAP2)Steap2 mCG_2960D3YUM61
MCG3124, isoform CRA_b (Macrophage migration inhibitory factor) (Putative uncharacterized protein)Mif mCG_3124Q545F01
MCG3634, isoform CRA_b (Putative uncharacterized protein)Skp1a mCG_3634Q5SUR31
MCG49140Gm10263 mCG_49140J3QNN81
MCG6979, isoform CRA_a (RIKEN cDNA 0610009B22 gene)0610009B22Rik mCG_6979Q8R3W21
MCG7614, isoform CRA_c (Putative uncharacterized protein) (Serine/arginine-rich-splicing factor 5)Srsf5 Sfrs5 mCG_7614Q9D8S51
MCG7941, isoform CRA_f (Phosphatidylethanolamine binding protein 1) (Putative uncharacterized protein)Pebp1 Pbp Pbp1 mCG_7941Q5EBQ21
MCG8382, isoform CRA_b (RNA-binding protein 4) (Rbm4 protein)Rbm4 mCG_8382Q5CZX81
MCG9626, isoform CRA_b (Myotubularin-related protein 3)Mtmr3 mCG_9626B1ATD51
MeckelinTmem67A2AJP51
Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67)Tmem67 Mks3Q8BR761
Mediator of DNA damage checkpoint protein 1Mdc1 Kiaa0170Q5PSV91
Mediator of DNA damage checkpoint protein 1Mdc1E9QK891
Mediator of RNA polymerase II transcription subunit 13 (Thyroid hormone receptor-associated protein 1) (Thyroid hormone receptor-associated protein complex 240 kDa component) (Trap240)Med13 Kiaa0593 Thrap1 Trap240Q5SWW41
Mediator of RNA polymerase II transcription subunit 14Med14A2BDN71
Mediator of RNA polymerase II transcription subunit 14Med14A2BDP01
Mediator of RNA polymerase II transcription subunit 16Med16E9QP841
Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92)Med16 Thrap5Q6PGF31
Mediator of RNA polymerase II transcription subunit 16 (Thyroid hormone receptor associated protein 5, isoform CRA_a)Med16 Thrap5 mCG_13375G3UW741
Mediator of RNA polymerase II transcription subunit 22 (Mediator complex subunit 22) (Surfeit locus protein 5) (Surf-5)Med22 Surf5Q622761
Mediator of RNA polymerase II transcription subunit 23Med23E9QNV21
Mediator of RNA polymerase II transcription subunit 23Med23F8WJB01
Mediator of RNA polymerase II transcription subunit 23 (Fragment)Med23H3BK331
Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit SOH1)Med31 Soh1Q9CXU11
Meiosis-specific nuclear structural protein 1Mns1Q618841
Meiotic recombination protein SPO11 (EC 5.99.1.3)Spo11Q9WTK81
Melanoma antigen, family D, 2 (Fragment)Maged2A2AG461
Melanoma antigen, family D, 2 (Fragment)Maged2A2AG471
Melanoma inhibitory activity protein 2Mia2E9PY901
Melanoma inhibitory activity protein 2Mia2E9Q3S21
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