EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)Phlpp2 PhlpplQ8BXA71
PH-interacting proteinPhipF8VQ931
PHD finger protein 10Phf10K4DI611
PHD finger protein 10 (BRG1-associated factor 45a) (BAF45a)Phf10 Baf45aQ9D8M71
PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog)Phf20 Hca58Q8BLG01
PHD finger protein 6Phf6E9QAG21
Phosducin-like protein (PHLP)Pdcl PhLP1Q9DBX21
Phosphatase and actin regulator 1Phactr1Q2M3X81
Phosphatidate cytidylyltransferase (EC 2.7.7.41)Cds2A2AMQ51
Phosphatidate cytidylyltransferase (EC 2.7.7.41) (Fragment)Cds2F6S4G21
Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (CDP-DAG synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog) (TAM41)Tamm41Q3TUH11
Phosphatidate cytidylyltransferase, mitochondrial (EC 2.7.7.41) (CDP-diacylglycerol synthase) (Mitochondrial translocator assembly and maintenance protein 41 homolog)Tamm41 1500001M20Rik mCG_130496G5E8811
Phosphatidate phosphatase LPIN1Lpin1E9QKQ51
Phosphatidate phosphatase LPIN1 (EC 3.1.3.4) (Fatty liver dystrophy protein) (Lipin-1)Lpin1 FldQ91ZP31
Phosphatidic acid phosphatase type 2c, isoform CRA_a (Phospholipid phosphatase 2)Plpp2 Ppap2c mCG_18216G3XA611
Phosphatidylcholine transfer proteinPctpQ5SV411
Phosphatidylcholine transfer protein (PC-TP) (START domain-containing protein 2) (StARD2) (StAR-related lipid transfer protein 2)Pctp Stard2P538081
Phosphatidylethanolamine-binding protein 1Pebp1D3Z1V41
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (EC 3.1.3.27) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase) (Protein-tyrosine phosphatase mitochondrial 1) (EC 3.1.3.16) (EC 3.1.3.48)Ptpmt1 PlipQ66GT51
Phosphatidylinositol 3-kinase (EC 2.7.1.137)Pik3c3D3YZ981
Phosphatidylinositol 3-kinase (EC 2.7.1.137)Pik3c3E9QLS61
Phosphatidylinositol 3-kinase regulatory subunit alpha (Phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (P85 alpha))Pik3r1Q80UI51
Phosphatidylinositol 3-kinase regulatory subunit gammaPik3r3B1AUG01
Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)Pik3r3Q641431
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3-kinase subunit alpha) (PI3K-alpha) (PI3Kalpha) (PtdIns-3-kinase subunit alpha) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha) (PtdIns-3-kinase subunit p110-alpha) (p110alpha) (Phosphoinositide-3-kinase catalytic alpha polypeptide) (Serine/threonine protein kinase PIK3CA) (EC 2.7.11.1)Pik3caP423371
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (PI3-kinase subunit delta) (PI3K-delta) (PI3Kdelta) (PtdIns-3-kinase subunit delta) (EC 2.7.1.153) (Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta) (PtdIns-3-kinase subunit p110-delta) (p110delta)Pik3cdO359041
Phosphatidylinositol 4-phosphate 5-kinase type-1 alphaPip5k1aD3YUY31
Phosphatidylinositol 4-phosphate 5-kinase type-1 gammaPip5k1cF8WHW61
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (Fragment)Pip4k2aF6RJE81
Phosphatidylinositol glycan anchor biosynthesis class U protein (Cell division cycle protein 91-like 1) (Protein CDC91-like 1) (GPI transamidase component PIG-U)Pigu Cdc91l1Q8K3581
Phosphatidylinositol transfer protein alpha isoformPitpnaJ3QQ301
Phosphatidylinositol-4-phosphate 5-kinase, type II, beta (Putative uncharacterized protein)Pip4k2b Pip5k2b mCG_13226Q3UJ951
Phosphatidylserine decarboxylase proenzyme, mitochondrialPisdD3YY631
Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase alpha chain; Phosphatidylserine decarboxylase beta chain]Pisd PISDE9PX911
Phosphatidylserine decarboxylase proenzyme, mitochondrial (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase beta chain; Phosphatidylserine decarboxylase alpha chain]PisdQ8BSF41
Phosphatidylserine decarboxylase proenzyme, mitochondrial (Fragment)PisdF7C3861
Phosphatidylserine synthase 2 (PSS-2) (PtdSer synthase 2) (EC 2.7.8.29) (Serine-exchange enzyme II)Ptdss2 Pss2Q9Z1X21
Phosphoacetylglucosamine mutase (PAGM) (EC 5.4.2.3) (Acetylglucosamine phosphomutase) (N-acetylglucosamine-phosphate mutase) (Phosphoglucomutase-3) (PGM 3)Pgm3 Agm1 Pgm-3Q9CYR61
Phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4)Pgam1 mCG_113582 mCG_133364 mCG_14289Q3U7Z61
Phosphoglycerate mutase (EC 5.4.2.11) (EC 5.4.2.4) (Fragment)BpgmD3YYH31
Phosphoinositide phospholipase C (EC 3.1.4.11)Plch1H3BKK41
Phosphoinositide phospholipase C (EC 3.1.4.11)Plch1I1E4X41
Phosphoinositide phospholipase C (EC 3.1.4.11)Plch1I1E4X61
Phosphoinositide phospholipase C (EC 3.1.4.11)Plcb4V9GXQ91
Phosphoinositide phospholipase C (EC 3.1.4.11)Plcb3Q3TWI41
Phosphoinositide phospholipase C (EC 3.1.4.11) (Fragment)Plcb4A2AT911
Phospholipase A2 (EC 3.1.1.4)Pla2g4aQ9DBX51
Phospholipase B1, membrane-associated (Phospholipase B) (Phospholipase B/lipase) (PLB/LIP) [Includes: Phospholipase A2 (EC 3.1.1.4); Lysophospholipase (EC 3.1.1.5)]Plb1 PlbQ3TTY01
Phospholipase D1 (PLD 1) (mPLD1) (EC 3.1.4.4) (Choline phosphatase 1) (Phosphatidylcholine-hydrolyzing phospholipase D1)Pld1Q9Z2801
Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (SAM, WWE and DDHD domain-containing protein 1)Ddhd2 Kiaa0725 Samwd1Q80Y981
Phospholipid scramblase 4 (PL scramblase 4) (Ca(2+)-dependent phospholipid scramblase 4)Plscr4P581961
Phospholipid transfer proteinPltpA2A5K21
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp9aA2AQC31
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp11cF6Q8D31
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp11b mCG_20276Q6DFW51
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp9a mCG_20648Q8C2881
Phospholipid-transporting ATPase (EC 3.6.3.1)Atp8b4A2ANX31
Phospholipid-transporting ATPase FetA (EC 3.6.3.1) (ATPase class I type 8B member 2-like protein) (ATPase class I type 8B member 5) (Flippase expressed in testis A)Atp8b5 FetaA3FIN41
Phospholipid-transporting ATPase ID (EC 3.6.3.1) (ATPase class I type 8B member 2) (P4-ATPase flippase complex alpha subunit ATP8B2)Atp8b2P981991
Phosphomannomutase (EC 5.4.2.8)Pmm1Q91W011
Phosphopantothenate--cysteine ligase (EC 6.3.2.5) (Phosphopantothenoylcysteine synthetase) (PPC synthetase)Ppcs CoabQ8VDG51
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)Pag1 Cbp PagQ3U1F91
Phosphoribosyl pyrophosphate synthase-associated protein 1 (Fragment)Prpsap1B1AT841
Phosphoribosyl pyrophosphate synthetase 1-like 1 (RIKEN cDNA 1700011K15)Prps1l1 1700011K15Rik mCG_48722Q8C5R81
Phosphoserine aminotransferase (Fragment)Psat1E9Q6P11
Phosphoserine phosphatase (Phosphoserine phosphatase, isoform CRA_b)Psph mCG_12439D3Z4T31
Phosphotriesterase-related protein (Fragment)PterA2AUR51
Phosphotriesterase-related protein (Fragment)PterA2AUR31
PILR alpha-associated neural proteinPianpA0A0N4SVY31
PILR alpha-associated neural protein (Brain protein 1) (PILR-associating neural protein) (Paired immunoglobin-like type 2 receptor-associating neural protein)Pianp PanpQ6P1B31
Pinin (Putative uncharacterized protein)PnnQ3TUQ51
Pituitary adenylate cyclase-activating polypeptide type I receptor (PACAP type I receptor) (PACAP-R-1) (PACAP-R1)Adcyap1r1P702051
Pituitary tumor-transforming gene 1 protein-interacting protein (Fragment)Pttg1ipF6TFF21
Piwi-like protein 2 (EC 3.1.26.-)Piwil2 MiliQ8CDG11
Plakophilin-4Pkp4A2AS451
Plasminogen activator inhibitor 1 (Serine (Or cysteine) peptidase inhibitor, clade E, member 1, isoform CRA_b)Serpine1 mCG_18018G5E8991
Plasminogen activator inhibitor 2, macrophage (PAI-2) (Serpin B2)Serpinb2 Pai2 Planh2P123881
Plasminogen receptor (KT) (Plg-R(KT))PlgrktQ9D3P81
Plastin-3Pls3B1AX581
Platelet derived growth factor, alpha (Platelet derived growth factor, alpha, isoform CRA_b) (Platelet-derived growth factor subunit A)Pdgfa mCG_23666Q99L561
Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (CD antigen CD42c)Gp1bbP564001
Platelet-activating factor acetylhydrolase 2, cytoplasmicPafah2E9QNW61
Platelet-activating factor acetylhydrolase IB subunit gammaPafah1b3D3Z7E61
Platelet-activating factor acetylhydrolase IB subunit gamma (Fragment)Pafah1b3D3Z2X51
Platelet-derived growth factor D (PDGF-D) (Spinal cord-derived growth factor B) (SCDGF-B) [Cleaved into: Platelet-derived growth factor D, latent form (PDGFD latent form); Platelet-derived growth factor D, receptor-binding form (PDGFD receptor-binding form)]Pdgfd ScdgfbQ925I71
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor)PdgfrbE9QN121
Pleckstrin (Putative uncharacterized protein)PlekQ8CAG61
Pleckstrin homology domain-containing family A member 2 (Fragment)Plekha2F8WIK51
Pleckstrin homology domain-containing family B member 2 (Fragment)Plekhb2D3Z3L21
Pleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2)Plekhf2Q91WB41
Pleckstrin homology domain-containing family G member 5Plekhg5B1AS671
Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX)Plekhg5 Kiaa0720 SyxQ66T021
Pleckstrin homology domain-containing family O member 1 (Fragment)Plekho1F6XQM21
Pleckstrin homology-like domain family A member 2 (Imprinted in placenta and liver protein) (Protein 50C15)Phlda2 Ipl Tssc3O089691
Pleckstrin homology-like domain family B member 1Phldb1D3Z0X51
Pleckstrin homology-like domain family B member 1Phldb1D3Z4N01
Pleckstrin homology-like domain family B member 2 (Fragment)Phldb2D3Z0691
Plectin (Fragment)PlecE9Q9J61
Pleiotropic regulator 1Plrg1D3Z4V11
Pleiotropic regulator 1Plrg1F8WI311
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