EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein FAM193AFam193aM0QWZ11
Protein FAM193BFam193b Kiaa1931Q3U2K01
Protein FAM207AFam207aP584681
Protein FAM210BFam210bQ9D8B61
Protein FAM214AFam214a Kiaa1370Q69ZK71
Protein FAM217AFam217aQ9D9W61
Protein FAM228AFam228aQ8CDW11
Protein FAM234BFam234b Kiaa1467Q8BYI81
Protein FAM32A (Ovarian tumor associated gene 12) (OTAG-12)Fam32a Otag12 MNCb-3154Q9CR801
Protein FAM45A (Putative uncharacterized protein) (RIKEN cDNA 1810055E12, isoform CRA_b)Fam45a 1810055E12Rik mCG_23044Q3TH341
Protein FAM50B (Protein XAP-5-like)Fam50b D0H6S2654E X5lQ9WTJ81
Protein FAM76BFam76bQ80XP81
Protein FAM83DFam83dQ9D7I81
Protein FAM83FFam83fQ3UKU41
Protein FAM89B (C184L ORF2 protein) (C184M protein) (MMTV receptor)Fam89b C184m Mtvr2Q9QUI11
Protein FAM92AFam92a Fam92a1Q8BP221
Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)Rpgrip1l Ftm Nphp8Q8CG731
Protein farnesyltransferase subunit betaFntbD3YWJ41
Protein farnesyltransferase subunit beta (FTase-beta) (EC 2.5.1.58) (CAAX farnesyltransferase subunit beta) (Ras proteins prenyltransferase subunit beta)FntbQ8K2I11
Protein fem-1 homolog B (FEM1b) (FEM1-beta) (Fem-1-like death receptor-binding protein alpha) (Fem-1-like in apoptotic pathway protein alpha) (F1A-alpha) (mt-Fem)Fem1b F1aa Kiaa0396Q9Z2G01
Protein GPR108 (Lung seven transmembrane receptor 2)Gpr108 Lustr2Q91WD01
Protein HGH1 homologHgh1 Brp16 Fam203a MNCb-5873Q8C3I81
Protein Hikeshi (RIKEN cDNA 0610007P06, isoform CRA_d)Hikeshi 0610007P06Rik mCG_22693G5E8I41
Protein inscuteable homolog (Minsc)InscQ3HNM71
Protein jagunal homolog 1Jagn1Q5XKN41
Protein JBTS17 (Protein C5orf42 homolog)Jbts17Q8CE721
Protein kinase C (EC 2.7.11.13)PrkcdQ1MX401
Protein kinase C (EC 2.7.11.13)PrkcdQ1MX421
Protein kinase C (EC 2.7.11.13)PrkcdQ1MX431
Protein kinase C (EC 2.7.11.13)Prkcg PrkccQ2NKI41
Protein kinase C and casein kinase II substrate protein 3 (Fragment)Pacsin3A6PWR11
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)Pacsin1 PacsinQ616441
Protein kinase C binding protein 1Zmynd8 Prkcbp1Q80Y821
Protein kinase C delta type (Protein kinase C, delta VI)PrkcdQ1MX411
Protein kinase C iota type (Fragment)PrkciF6QWV41
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)Prkcz PkczQ029561
Protein LEG1 homologLeg1Q8C6C91
Protein lifeguard 1 (Glutamate [NMDA] receptor-associated protein 1) (NMDA receptor glutamate-binding subunit)Grina Lag Lfg1 Nmdara1Q9ESF41
Protein lifeguard 2 (Fas apoptotic inhibitory molecule 2) (Neural membrane protein 35)Faim2 Kiaa0950 Lfg Lfg2 Nmp35Q8K0971
Protein lifeguard 3 (Responsive to centrifugal force and shear stress gene 1 protein) (Protein RECS1) (Transmembrane BAX inhibitor motif-containing protein 1)Tmbim1 Lfg3 Recs1Q8BJZ31
Protein lin-28 homolog A (Lin-28A) (Testis-expressed protein 17)Lin28a Lin28 Tex17Q8K3Y31
Protein lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Vertebrate lin-7 homolog 1) (Veli-1)Lin7a Mals1 Veli1Q8JZS01
Protein lin-7 homolog B (Lin-7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2)Lin7b Mals2 Veli2O889511
Protein LSM14 homolog A (Fragment)Lsm14aF6X2V91
Protein LSM14 homolog B (Putative uncharacterized protein)Lsm14b BC040823Q8BM411
Protein lunapark (Protein ulnaless)Lnp Kiaa1715 UlnQ7TQ951
Protein LZIC (Fragment)LzicB1AS041
Protein LZIC (Leucine zipper and CTNNBIP1 domain-containing protein) (Leucine zipper and ICAT homologous domain-containing protein)LzicQ8K3C31
Protein MAK16 homolog (Protein RBM13)Mak16 Rbm13Q8BGS01
Protein MCM10 homologMcm10Q0VBD21
Protein misato homolog 1Msto1D3YX871
Protein MMS22-likeMms22lG8JL471
Protein MMS22-like (Fragment)Mms22lG3UXR91
Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like)Mms22lB1AUR61
Protein naked cuticle homolog 2 (Naked-2) (mNkd2)Nkd2Q8VE281
Protein Njmu-R10Q9CYI01
Protein NLRC5Nlrc5C3VPR61
Protein NPATNpatQ8BMA51
Protein NRDE2 homologNrde2Q80XC61
Protein odr-4 homolog (mODR-4)Odr4Q4PJX11
Protein OS-9Os9Q8K2C71
Protein phosphatase 1 regulatory subunit 12C (Fragment)Ppp1r12cF6XWD41
Protein phosphatase 1 regulatory subunit 1A (Protein phosphatase inhibitor 1) (I-1) (IPP-1)Ppp1r1aQ9ERT91
Protein phosphatase 1 regulatory subunit 1B (DARPP-32) (Dopamine- and cAMP-regulated neuronal phosphoprotein)Ppp1r1bQ608291
Protein phosphatase 1 regulatory subunit 21 (Coiled-coil domain-containing protein 128) (KLRAQ motif-containing protein 1)Ppp1r21 Ccdc128 Klraq1Q3TDD91
Protein phosphatase 1 regulatory subunit 37 (Leucine-rich repeat-containing protein 68)Ppp1r37 Lrrc68Q8BKR51
Protein phosphatase 1, regulatory (inhibitor) subunit 9APpp1r9aH3BJD01
Protein phosphatase 1, regulatory (inhibitor) subunit 9APpp1r9aH3BJD61
Protein phosphatase 1, regulatory (inhibitor) subunit 9A (Fragment)Ppp1r9aH3BL281
Protein phosphatase 1, regulatory (inhibitor) subunit 9A (Putative uncharacterized protein)Ppp1r9aQ3UXW41
Protein phosphatase 1L (EC 3.1.3.16) (Protein phosphatase 1-like) (Protein phosphatase 2C isoform epsilon) (PP2C-epsilon)Ppm1l Kiaa4175Q8BHN01
Protein phosphatase 2 (Formerly 2A), regulatory subunit A (PR 65), beta isoform, isoform CRA_b (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform)Ppp2r1b mCG_4175H3BKU11
Protein phosphatase inhibitor 2 (IPP-2)Ppp1r2Q9DCL81
Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (mSSH-3L)Ssh3 Ssh3lQ8K3301
Protein PMLPmlD3YXR51
Protein PMLPmlD3Z3A61
Protein polybromo-1Pbrm1D3Z1N41
Protein polybromo-1Pbrm1D3Z1W61
Protein polybromo-1Pbrm1E9Q4Y51
Protein polybromo-1Pbrm1E9Q7L21
Protein polybromo-1Pbrm1E9Q7L31
Protein polybromo-1Pbrm1F8VQD11
Protein polybromo-1 (Fragment)Pbrm1F6THL51
Protein PRRC2CPrrc2cS4R2J91
Protein prune homolog 2 (BNIP2 motif-containing molecule at the C-terminal region 1)Prune2 Bmcc1 Kiaa0367Q52KR31
Protein regulator of cytokinesis 1 (Protein regulator of cytokinesis 1, isoform CRA_e)Prc1 mCG_19465G3UW861
Protein RER1Rer1Q9CQU31
Protein RUFY3 (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein 1) (Singar1)Rufy3 D5Bwg0860e RipxQ9D3941
Protein S100 (S100 calcium-binding protein)S100a1 mCG_68132Q91V771
Protein S100 (S100 calcium-binding protein)S100b mCG_3101Q3UY001
Protein S100-A1 (S-100 protein alpha chain) (S-100 protein subunit alpha) (S100 calcium-binding protein A1)S100a1P565651
Protein S100-A1 (S100 calcium binding protein A1, isoform CRA_a)S100a1 mCG_68132D3YUT61
Protein S100-A13 (S100 calcium-binding protein A13)S100a13P973521
Protein S100-B (S-100 protein beta chain) (S-100 protein subunit beta) (S100 calcium-binding protein B)S100bP501141
Protein salvador homolog 1 (45 kDa WW domain protein) (mWW45)Sav1 Ww45 Wwp3Q8VEB21
Protein SCAF8 (RNA-binding motif protein 16) (SR-related and CTD-associated factor 8)Scaf8 Kiaa1116 Rbm16Q6DID31
Protein SCO2 homolog, mitochondrialSco2Q8VCL21
Protein sel-1 homolog 1Sel1lJ3QJX31
Protein SERAC1 (Serine active site-containing protein 1)Serac1 D17Ertd141eQ3U2131
Protein SET (Fragment)SetA2BE931
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