EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Regulating synaptic membrane exocytosis protein 1 (Fragment)Rims1E9PWP61
Regulation of nuclear pre-mRNA domain-containing protein 1A (Cyclin-dependent kinase inhibitor 2B-related protein) (p15INK4B-related protein)Rprd1a Kiaa4077 P15rsQ8VDS41
Regulation of nuclear pre-mRNA domain-containing protein 1B (Fragment)Rprd1bF6YB251
Regulation of nuclear pre-mRNA domain-containing protein 1B (Fragment)Rprd1bF7DAY51
Regulator of G-protein signaling 4 (RGS4)Rgs4O088991
Regulator of G-protein signaling 7-binding protein (R7 family-binding protein)Rgs7bp D13Bwg1146e R7bpQ8BQP91
Regulator of G-protein-signaling 19Rgs19B7ZCT11
Regulator of microtubule dynamics protein 3 (RMD-3) (mRMD-3) (Protein FAM82A2) (Protein FAM82C)Rmdn3 Fam82a2 Fam82cQ3UJU91
Regulatory factor X, 7Rfx7F8VPJ61
Remodeling and spacing factor 1Rsf1E9PWW91
Replication factor C 1, isoform CRA_c (Replication factor C subunit 1)Rfc1 Recc1 mCG_10254G3X8Z61
Replication factor C subunit 1Rfc1G3UWX11
Replication factor C subunit 1 (Rfc1 protein)Rfc1G3UXL41
Replication factor C subunit 1 (Rfc1 protein)Rfc1Q5U4B11
Repulsive guidance molecule A (RGM domain family member A)RgmaQ6PCX71
REST corepressor 1 (Protein CoREST)Rcor1 D12Wsu95e Kiaa0071K3W4P91
REST corepressor 3Rcor3Q6PGA01
Reticulocalbin-3Rcn3 D7Ertd671eQ8BH971
Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI)Rtn2 Nspl1O706221
Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor) (Nogo66 receptor-1) (NgR1)Rtn4r Ngr1 NogorQ99PI81
Reticulophagy receptor Fam134bFam134bQ8VE911
Reticulophagy receptor Fam134bFam134bE9QPM11
Retinal dehydrogenase 2 (RALDH 2) (RalDH2) (EC 1.2.1.36) (Aldehyde dehydrogenase family 1 member A2) (Retinaldehyde-specific dehydrogenase type 2) (RALDH(II))Aldh1a2 Aldh1a7 Raldh2Q621481
Retinoic acid early-inducible protein 1-epsilon (RAE-1-epsilon)Raet1eQ9CZQ61
Retinoic acid receptor responder protein 2 (Chemerin)Rarres2Q9DD061
Retinoic acid receptor RXR-beta (Fragment)RxrbG3UXP81
Retinoic acid receptor RXR-beta (MHC class I regulatory element-binding protein H-2RIIBP) (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta)Rxrb Nr2b2P287041
Retinoic acid receptor RXR-gammaRxrgE9Q9V91
Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)Rxrg Nr2b3P287051
Retinol dehydrogenase 13 (EC 1.1.1.-)Rdh13Q8CEE71
Retinol dehydrogenase 14 (EC 1.1.1.-) (Alcohol dehydrogenase PAN2)Rdh14Q9ERI61
Retinol dehydrogenase type 1Rdh1Q8VIJ71
Retrotransposon-derived protein PEG10Peg10E9Q3F71
Retrotransposon-derived protein PEG10Peg10H3BJQ11
Retrotransposon-like protein 1 (Mammalian retrotransposon derived protein 1) (Paternally expressed gene 11 protein) (Retrotransposon-derived protein PEG11)Rtl1 Mar1 Mart1 Peg11Q7M7321
Rho GTPase activating protein 12 (Rho GTPase-activating protein 12)Arhgap12B2RUJ81
Rho GTPase-activating protein 12Arhgap12S4R2211
Rho GTPase-activating protein 12Arhgap12S4R2481
Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12)Arhgap12Q8C0D41
Rho GTPase-activating protein 15 (ArhGAP15) (Rho-type GTPase-activating protein 15)Arhgap15Q811M11
Rho GTPase-activating protein 17Arhgap17E9QAJ91
Rho GTPase-activating protein 21Arhgap21B7ZCJ01
Rho GTPase-activating protein 21Arhgap21B7ZCJ11
Rho GTPase-activating protein 21 (Fragment)Arhgap21G3UWM51
Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)Arhgap21 Arhgap10 Kiaa1424Q6DFV31
Rho GTPase-activating protein 23Arhgap23F8VQ111
Rho GTPase-activating protein 23 (Rho-type GTPase-activating protein 23)Arhgap23 Kiaa1501 MNCb-1301Q69ZH91
Rho GTPase-activating protein 29 (Rho-type GTPase-activating protein 29)Arhgap29Q8CGF11
Rho GTPase-activating protein 31 (Cdc42 GTPase-activating protein)Arhgap31 Cdgap Kiaa1204A6X8Z51
Rho GTPase-activating protein 39Arhgap39 D15Wsu169e Kiaa1688P592811
Rho GTPase-activating protein 39Arhgap39H7BX461
Rho GTPase-activating protein 5 (Rho-type GTPase-activating protein 5) (p190-B)Arhgap5 Rhogap5P973931
Rho guanine nucleotide exchange factor (GEF) 11Arhgef11Q68FM71
Rho guanine nucleotide exchange factor 10Arhgef10 Kiaa0294Q8C0331
Rho guanine nucleotide exchange factor 12Arhgef12F8VQN61
Rho guanine nucleotide exchange factor 2Arhgef2H3BJ451
Rho guanine nucleotide exchange factor 2Arhgef2H3BJX81
Rho guanine nucleotide exchange factor 2Arhgef2H3BKH91
Rho guanine nucleotide exchange factor 2 (Rho/rac guanine nucleotide exchange factor (GEF) 2, isoform CRA_b)Arhgef2 mCG_8844H3BJ401
Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF)Arhgef25 D10Ertd610e GeftQ9CWR01
Rho guanine nucleotide exchange factor 3Arhgef3Q91X461
Rho guanine nucleotide exchange factor 37Arhgef37E9Q5R61
Rho guanine nucleotide exchange factor 39 (Fragment)Arhgef39 E130306D19RikF6V6951
Rho guanine nucleotide exchange factor 40Arhgef40S4R1891
Rho guanine nucleotide exchange factor 40Arhgef40S4R2U91
Rho-related GTP-binding protein RhoE (Rho family GTPase 3) (Rnd3)Rnd3 Arhe RhoeP615881
Rho-related GTP-binding protein RhoFRhof ArhfQ8BYP31
Riboflavin kinase (EC 2.7.1.26) (ATP:riboflavin 5'-phosphotransferase) (Flavokinase) (KOI-4)RfkQ8CFV91
Ribonuclease (EC 3.1.26.-)Rnaseh2aQ05C511
Ribonuclease (EC 3.1.26.-) (Fragment)Rnaseh2aF6RP291
Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III)Drosha Etohi2 Rn3 RnasenQ5HZJ01
Ribonuclease P protein subunit p20 (RNaseP protein p20) (EC 3.1.26.5)Pop7 Rpp20Q9DCH21
Ribonuclease P protein subunit p21 (RNaseP protein p21) (EC 3.1.26.5) (Ribonucleoprotein V)Rpp21 Cat60Q8R0401
Ribonuclease P protein subunit p25 (RNase P protein subunit p25) (EC 3.1.26.5)Rpp25Q91WE31
Ribonuclease P protein subunit p25-like protein (RNase P protein subunit-like p25) (Rpp25-like protein)Rpp25lQ99JH11
Ribonuclease T2 (EC 3.1.27.-) (Ribonuclease 6)Rnaset2 Rnase6plQ9CQ011
Ribosomal oxygenase 2Riox2 MinaD3YTU31
Ribosomal protein 63, mitochondrial (Mitochondrial ribosomal protein 63) (Mitochondrial ribosomal protein L57) (mMRP63)Mrpl57 Mrp63Q9CQF81
Ribosomal protein S6 kinase (EC 2.7.11.1)Rps6ka1E9PWV31
Ribosomal protein S6 kinase (EC 2.7.11.1)Rps6ka1F6RQA21
Ribosomal protein S6 kinase (EC 2.7.11.1)Rps6ka1Q505N61
Ribosomal protein S6 kinase alpha-1Rps6ka1G3UZI31
Ribosomal protein S6 kinase alpha-1 (Fragment)Rps6ka1F6Q8A41
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (p70 ribosomal S6 kinase beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB)Rps6kb2Q9Z1M41
Ribosomal RNA-processing protein 1 homolog B (Fragment)Rrp1bF7AGW81
Ribosomal RNA-processing protein 7 homolog A (Gastric cancer antigen Zg14 homolog)Rrp7aQ9D1C91
Ribosomal RNA-processing protein 8Rrp8E9PVA21
Ribosome biogenesis protein BRX1 homolog (Fragment)Brix1F6WEP71
Ribosome maturation protein SBDS (Fragment)SbdsF6TN031
Ribosome-recycling factor, mitochondrial (RRF) (Ribosome-releasing factor, mitochondrial)MrrfQ9D6S71
Ribosome-releasing factor 2, mitochondrial (Fragment)Gfm2E0CXH21
Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2)Gfm2 Efg2Q8R2Q41
Ribosome-releasing factor 2, mitochondrial (RRF2mt) (Elongation factor G 2, mitochondrial) (EF-G2mt) (mEF-G 2)Gfm2 EFG2 GFM2E9Q7N51
RIKEN cDNA 0610037L13 gene (Fragment)0610037L13RikA2A8E41
RIKEN cDNA 1700003F12 gene1700003F12RikA2AKE51
RIKEN cDNA 1700025G04 gene1700025G04RikA0A0A0MQF71
RIKEN cDNA 1700037H04 gene (Fragment)1700037H04RikH7BXB91
RIKEN cDNA 1810048P08, isoform CRA_d (Rab43 protein) (Ras-related protein Rab-43)Rab43 1810048P08Rik mCG_141535Q91Z341
RIKEN cDNA 2010300C02 gene2010300C02RikE9Q3M91
RIKEN cDNA 2010300C02 gene (Fragment)2010300C02RikF7B0R91
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