EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Delta-aminolevulinic acid dehydratase (EC 4.2.1.24)B195_17509M5QVP81
Delta-aminolevulinic acid dehydratase (EC 4.2.1.24)hemB MXAN_4100Q1D4Z51
DeoR-family transcriptional regulatorCD196_2694A0A0H3NET21
Deoxycytidylate deaminaseVSAK1_04157A6D6621
Deoxyguanosinetriphosphate triphosphohydrolase (EC 3.1.5.1)dgt FTT_0720cQ5NGV81
Deoxyguanosinetriphosphate triphosphohydrolase-like proteinFTN_0632A0Q5L01
Deoxyguanosinetriphosphate triphosphohydrolase-like proteinFTN_0587A0Q5G71
Deoxyguanosinetriphosphate triphosphohydrolase-like proteindgt HPSD74_1484U4SI771
Deoxyribodipyrimidine photolyasephr PA4660Q9HVD21
Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase)deoC Caur_0701A9WFK21
Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase)deoC CPC_2301B1BIG51
Deoxyribose-phosphate aldolase (DERA) (EC 4.1.2.4) (2-deoxy-D-ribose 5-phosphate aldolase) (Phosphodeoxyriboaldolase) (Deoxyriboaldolase)deoC SPy_1867 M5005_Spy1585Q99Y511
Dephospho-CoA kinase (EC 2.7.1.24) (Dephosphocoenzyme A kinase)coaE spr0873Q8DQ321
Dephospho-CoA kinase (EC 2.7.1.24) (Dephosphocoenzyme A kinase)coaE SPy_0498 M5005_Spy0409P581021
Dextran glucosidase (EC 3.2.1.10)dexB SPy_1973Q99XX71
DgcB, Dimethylglycine catabolismdgcB PA5399Q9HTG51
dGTP triphosphohydrolaseFphi_0205B0TYQ71
DHH family proteinCPC_3051B1BI821
Diacylglycerol acyltransferase/mycolyltransferase Ag85A (DGAT) (EC 2.3.1.122) (EC 2.3.1.20) (Acyl-CoA:diacylglycerol acyltransferase) (Antigen 85 complex A) (85A) (Ag85A) (Fibronectin-binding protein A) (Fbps A)fbpA mpt44 Rv3804c MTV026.09cP9WQP31
Diacylglycerol acyltransferase/mycolyltransferase Ag85B (DGAT) (EC 2.3.1.122) (EC 2.3.1.20) (30 kDa extracellular protein) (Acyl-CoA:diacylglycerol acyltransferase) (Antigen 85 complex B) (85B) (Ag85B) (Extracellular alpha-antigen) (Fibronectin-binding protein B) (Fbps B)fbpB Rv1886c MTCY180.32P9WQP11
Diacylglycerol acyltransferase/mycolyltransferase Ag85C (DGAT) (EC 2.3.1.122) (EC 2.3.1.20) (Acyl-CoA:diacylglycerol acyltransferase) (Antigen 85 complex C) (85C) (Ag85C) (Fibronectin-binding protein C) (Fbps C)fbpC mpt45 Rv0129c MTCI5.03cP9WQN91
Diacylglycerol kinase (DAGK) (EC 2.7.1.107) (Diglyceride kinase) (DGK)dgkA HP_0700P564111
Diacylglycerol kinase (EC 2.7.1.107)dgkA-I PP_1636Q88MD71
Diadenylate cyclase (DAC) (EC 2.7.7.85) (Cyclic-di-AMP synthase) (c-di-AMP synthase)dacA SPy_1036Q99ZX01
Diadenylate cyclase (DAC) (EC 2.7.7.85) (Cyclic-di-AMP synthase) (c-di-AMP synthase)dacA SAOUHSC_02407Q2FW921
Diadenylate cyclase (DAC) (EC 2.7.7.85) (Cyclic-di-AMP synthase) (c-di-AMP synthase)dacA LMRG_01274A0A0H3GM481
Diaminobutyrate--2-oxoglutarate aminotransferase (EC 2.6.1.76) (Diaminobutyrate transaminase) (L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase) (DABA aminotransferase) (DABA-AT) (L-diaminobutyric acid transaminase)datP567441
Diaminopimelate decarboxylase (DAP decarboxylase) (DAPDC) (EC 4.1.1.20)lysA PA5277P195721
Diaminopimelate decarboxylase (DAP decarboxylase) (DAPDC) (EC 4.1.1.20)lysA VSAK1_12300A6D6V11
Diaminopropionate ammonia-lyase (EC 4.3.1.15)VSAK1_18499A6CXM71
Dicarboxylate symporter family proteinKW89_1332A0A0K2DWS01
Dicarboxylate symporter family proteinKW89_2822A0A0K2E1331
Dienelactone hydrolase family proteinMXAN_7109Q1CWK11
Dihydrodipicolinate synthetaseB195_04127M5QZA11
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-)B195_09122M5QX701
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-)MXAN_4217Q1D4N11
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-)acoC SPy_1029Q99ZX61
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-)SAOUHSC_01042Q2G2A41
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-)SAOUHSC_01611Q2FY541
Dihydrolipoamide dehydrogenase (EC 1.8.1.4)OOM_0702I2AYE91
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)Fphi_1187B0TXF41
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdA1 NMB0957Q9JZP51
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)B195_20310M5QCQ41
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)B195_09117M5QLG41
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdA STM0154Q8ZRT01
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdG PP_4187Q88FB11
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpd YPO3417Q7CKE41
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)SC1083_0759G4A7G31
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)OOM_0733I2AYH61
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdA Smlt4120B2FHZ71
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdA SCH_0153Q57TA21
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)SAOUHSC_01043Q2G2A31
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpd FTT_1483cQ5NEX41
Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of branched-chain alpha-keto acid dehydrogenase complex) (LPD-Val)bfmBC yqiV BSU24060P545331
Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase) (E3 component of pyruvate complex) (Membrane-bound ribosome protein complex 50 kDa subunit)pdhD MW0979P0A0E71
Dihydrolipoyl dehydrogenase (LPD) (EC 1.8.1.4) (Component of peroxynitrite reductase/peroxidase complex) (Component of PNR/P) (Dihydrolipoamide dehydrogenase) (E3 component of alpha-ketoacid dehydrogenase complexes)lpdC lpd Rv0462 MTV038.06P9WHH91
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Component of peroxynitrite reductase/peroxidase complex) (Component of PNR/P) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDH component E2)dlaT sucB Rv2215 MTCY190.26P9WIS71
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2)pdhC MW0978Q8NX761
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)Fphi_0974B0TWT91
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)B195_20305M5QQI71
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)sucB YPO1114Q7CH471
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)sucB MXAN_6036Q1CZK21
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)sucB S0583 SF0570 AJR25_003745 AJR27_005245Q83S961
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)sucB HPSD74_0792U4SLL11
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)OOM_0572I2AY431
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)sucB SCH_0741Q57RL41
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)sucB FTT_0077Q5NIJ01
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex)odhB sucB SAOUHSC_01416Q2FYM21
Dihydroneopterin aldolase (DHNA) (EC 4.1.2.25) (7,8-dihydroneopterin aldolase)folB folQ SPy_1099 M5005_Spy0823P0C0G51
Dihydroorotase (DHOase) (EC 3.5.2.3)pyrC YPO1587 y1746 YP_2265Q8ZFU41
Dihydroorotase (DHOase) (EC 3.5.2.3)pyrC Rv1381 MTCY02B12.15P9WHL31
Dihydroorotase (DHOase) (EC 3.5.2.3)pyrC SPy_0907 M5005_Spy0709Q9A0711
Dihydroorotase (EC 3.5.2.3)Fphi_0802B0TWB61
Dihydroorotase (EC 3.5.2.3)pyrC FTN_0024A0Q3X01
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2)pyrD Cj0804Q0PA861
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2)SAOUHSC_02909Q2FV301
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (DHOdehase) (DHOD) (DHODase) (Dihydroorotate oxidase)pyrD PP_2095Q88L401
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (DHOdehase) (DHOD) (DHODase) (Dihydroorotate oxidase)pyrD VSAK1_05275A6D6F91
Dihydropteroate synthase (DHPS) (EC 2.5.1.15) (Dihydropteroate pyrophosphorylase)folP SPy_1098 M5005_Spy0822P0C0G11
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD Fphi_1547B0TZC01
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD FTN_1043A0Q6R51
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD PA0353Q9I6E01
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD Rv0189c MTCI28.28cP9WKJ51
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD SFV_3731Q0SYW31
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD b3771 JW5605P057911
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD SAOUHSC_02281Q2FWK71
Dipeptidase (EC 3.4.14.-)pepV spr0547Q8DQQ61
Dipeptidase-related proteinPG_1313Q7MV051
Dipeptide ABC transporter periplasmic dipeptide-binding protein DppA 1B195_12301M5QJM81
Dipeptide ABC transporter periplasmic dipeptide-binding protein DppA 3B195_12286M5QHF01
Dipeptide ABC transporter-putative membrane subunit (EC 3.6.3.23)dppC PP_0880Q88PH01
Dipeptide ABC transporter-putative membrane subunit (EC 3.6.3.23)dppB PP_0881Q88PG91
Dipeptide transport proteindppA STM3630Q8ZLA91
Dipeptide transport system permease proteindppB YPO4002Q7CG191
Dipeptidyl peptidase 11dpp11 PG_1283Q7MV251
dITP/XTP pyrophosphatase (EC 3.6.1.66) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)SPy_0362 M5005_Spy0304Q9A1B61
Divalent metal cation transporter MntHmntH LMRG_00876A0A0H3GK751
DksA-like proteinMXAN_3006Q1D8081
DNA damage-inducible protein FdinF b4044 JW4004P283031
DNA gyrase subunit A (EC 5.99.1.3)gyrA MW0006Q8NKW81
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