EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Deleted.0A3M9374
Deleted.0A3M8C24
Deleted.0A3M7J44
Deleted.0D1GPE44
Deleted.0D1GS824
Deleted.0D1GRK64
Deleted.0D1GS814
Deleted.0D1GPE74
Deleted.0D1GNV74
Deleted.0D1GTJ64
Deleted.0D1GRK14
Deleted.0D1GQU04
Deleted.0D1GSJ44
Deleted.0D1GRV04
Deleted.0D1GTI84
Deleted.0D1GP834
Deleted.0D1GRL74
Deleted.0D1GS794
Deleted.0D1GS754
Deleted.0D1GS804
Deleted.0D1GQ114
Deleted.0D1GS404
Deleted.0D1GSJ84
Deleted.0D1GRF04
Deleted.0D1GN784
Deleted.0D1GUM34
Deleted.0D1GRZ54
Deleted.0Q5F9Z44
Deleted.0Q5F6R04
Deleted.0Q5F6Q94
Deleted.0Q5F6C24
Deleted.0B5E6584
Deleted.0C1CI284
Deleted.0C1CPH34
Deleted.0G0GKM54
Deleted.0A0A0D8VW664
Deleted.0A0A0A8KCH04
Deleted.0A0A075L8Q84
Deleted.0A0A026HH944
Deleted.0A0A0E2U8C84
Deleted.0A0A0D8VXA84
Deleted.0H9UZX84
Deleted.0A0A0E3KPJ24
Deleted.0B3HF454
Deleted.0A0A075L0V34
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (EC 3.6.1.23) (dUTP pyrophosphatase)dut AC067_10070 AWP75_16375 BUE81_08565A0A0A7XZ224
DhcB, dehydrocarnitine CoA transferase, subunit BdhcB PA2000Q9I2A94
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)lpdA MXAN_4219Q1D4M94
Dihydrolipoyl dehydrogenase (EC 1.8.1.4)NGO_0562Q5F9424
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (E2)aceF b0115 JW0111P069594
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2)NGO_0916Q5F8754
Dihydroorotase (DHOase) (EC 3.5.2.3)pyrC ECS88_1076B7MIK34
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (DHOdehase) (DHOD) (DHODase) (Dihydroorotate oxidase)pyrD NGO1761Q5F6054
Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) (DHOdehase) (DHOD) (DHODase) (Dihydroorotate oxidase)pyrD PA3050Q9HZF84
Dihydropteroate synthase (DHPS) (EC 2.5.1.15) (Dihydropteroate pyrophosphorylase)sul2 folP2 sulII AA102_27005 BE963_00620 BUE81_17055 ERS085406_05113 ETN48_p0112 HMPREF3040_00003 MJ49_26055 pO103_81B7JCH44
Dihydroxy-acid dehydratase (DAD) (EC 4.2.1.9)ilvD NGO0809Q5F8G64
Dihydroxyacetone kinase (Dihydroxyacetone kinase subunit DhaK)BE932_30525 SY51_06850A0A066ST594
Dipeptidyl carboxypeptidase IIBE932_03245 SY51_08810A0A066T0944
dITP/XTP pyrophosphatase (EC 3.6.1.66) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase)rdgB AC067_24955 BE949_25840 BHF46_06070 BK373_14965 BK375_07580 ERS085366_00784 ERS139235_00065 MJ49_16180 UC41_04895A0A023LEL94
DNA gyrase subunit A (EC 5.99.1.3)gyrA NGO_0629Q5F8Y04
DNA methylaseNGO_1504Q5F6P54
DNA polymerase INGO_2103Q5F5334
DNA polymerase III subunit beta (EC 2.7.7.7)dnaN PA0002Q9I7C44
DNA protection during starvation protein (EC 1.16.-.-)dps EC1303_c07830A0A0E1LZH74
DNA-binding competence protein 2 (DNA-binding competence protein 4)NGO_1304 NGO_1902Q5F5M04
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)rpoA NGO1818Q5F5V24
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)rpoB groN nitB rif ron stl stv tabD b3987 JW3950P0A8V24
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)rpoB NGO1851Q5F5R54
DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta')rpoC tabB b3988 JW3951P0A8T74
DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta')rpoC NGO1850Q5F5R64
DSBA oxidoreductaseNGO_1717Q5F6494
dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) (Thymidine diphospho-4-keto-rhamnose 3,5-epimerase)rmlC BE932_07645 BET08_08615 SY51_11825A0A066T4C04
dTDP-glucose 4,6-dehydratase (EC 4.2.1.46)rmlB PA5161Q9HU244
dTDP-glucose 4,6-dehydratase (EC 4.2.1.46)rmlB BE932_07660 BET08_08600 SY51_11840A0A066SWC54
Electron transfer flavoprotein subunit betaNGO_1936Q5F5I84
Elongation factor 4 (EF-4) (EC 3.6.5.n1) (Ribosomal back-translocase LepA)lepA NGO0344Q5F9P94
Elongation factor 4 (EF-4) (EC 3.6.5.n1) (Ribosomal back-translocase LepA)lepA SY51_14710A0A061YLN54
Elongation factor G (EF-G)fusA NGO1843Q5F5S34
Elongation factor P (EF-P)efp PA2851Q9HZZ24
Elongation factor Ts (EF-Ts)tsf NGO1974Q5F5F44
Elongation factor Tu (EF-Tu)tuf1 NGO1842; tuf2 NGO1858Q5F5Q84
Elongation factor Tu (EF-Tu)tufB tuf Smlt0890 Smlt0904B2FQ314
Elongation factor Tu (EF-Tu)tuf LMRG_02198A0A0H3GG294
Endolytic murein transglycosylase (EC 4.2.2.-) (Peptidoglycan polymerization terminase)mltG LMRG_01471A0A0H3GKD44
Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase)eno NMB1285Q9JZ534
Enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (2-phosphoglycerate dehydratase)eno NGO0617Q5F8Z24
Enoyl-[acyl-carrier-protein] reductase [NADH] (ENR) (EC 1.3.1.9) (Trans-2-enoyl-CoA reductase) (TER) (EC 1.3.1.44)fabV PA2950Q9HZP84
Erythronate-4-phosphate dehydrogenase (EC 1.1.1.290)pdxB BE932_09215 SY51_13245A0A061YIH24
EsteraseNGO_1949Q5F5H64
Ethanol-active dehydrogenase/acetaldehyde-active reductaseadhP NGO_1442Q5F6V34
FAD:protein FMN transferase (EC 2.7.1.180) (Flavin transferase)LMRG_02181A0A0H3GJF74
Ferredoxin-NADP reductaseNGO_0687Q5F8S34
Ferric enterobactin receptor PirApirA PA0931Q9I5274
Ferrioxamine receptor FoxAfoxA PA2466Q9I1164
FetANGO_2093Q5F5434
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (PPIase) (EC 5.2.1.8) (Rotamase)fkpA yzzS b3347 JW3309P455234
Flagellar basal-body rod protein FlgG (Distal rod protein)flgG PA1082Q9I4P74
Flagellar hook protein FlgESmlt2314B2FQV54
Flagellar hook-associated protein 1 (HAP1) (FlgK)HP_1119O257444
Flagellar hook-associated protein 2 (HAP2) (Filament cap protein) (Flagellar cap protein)fliD HP_0752P967864
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