EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Fructose-bisphosphate aldolase (EC 4.1.2.13)cbbA NMB1869Q9JXV51
Fructose-bisphosphate aldolase (FBP aldolase) (FBPA) (EC 4.1.2.13) (Fructose-1,6-bisphosphate aldolase)fba Rv0363c MTCY13E10.25cP9WQA31
Fructose-bisphosphate aldolase (FBP aldolase) (FBPA) (EC 4.1.2.13) (Fructose-1,6-bisphosphate aldolase)fba SPy_1889 M5005_Spy1607P689051
Fructose-bisphosphate aldolase class 1 (EC 4.1.2.13) (Fructose-bisphosphate aldolase class I) (FBP aldolase)fda fbaB PG_1755P600531
Fructose-bisphosphate aldolase class 1 (EC 4.1.2.13) (Fructose-bisphosphate aldolase class I) (FBP aldolase)fda SAOUHSC_02926Q2FV171
Fructose-bisphosphate aldolase class 2 (FBP aldolase) (FBPA) (EC 4.1.2.13) (Fructose-1,6-bisphosphate aldolase) (Fructose-bisphosphate aldolase class II)fbaA SF2910 S3110P0AB731
Fructose-bisphosphate aldolase class 2 (FBP aldolase) (FBPA) (EC 4.1.2.13) (Fructose-1,6-bisphosphate aldolase) (Fructose-bisphosphate aldolase class II)fbaA fba fda b2925 JW2892P0AB711
Fructose-bisphosphate aldolase class II (EC 4.1.2.13)fba YPO0920Q7CGS51
Fructose-bisphosphate aldolase, class II (EC 4.1.2.13)fbaA HPSD74_1942U4SAZ01
Fructose-bisphosphate aldolase, class II (EC 4.1.2.13)fbaA FSU_0150C9RP041
Fructose-specific PTS system IIB componentLMRG_00119A0A0H3GDY01
FtsK/SpoIIIE DNA translocase TcpAtcpA pTet_023G5DSN81
FtsK/SpoIIIE family cell division proteinPGN_0487B2RI111
Fumarate hydratase class I (EC 4.2.1.2)Fphi_0489B0U0F61
Fumarate hydratase class I (EC 4.2.1.2)B195_07105M5R1U81
Fumarate hydratase class I (EC 4.2.1.2)fumB MXAN_3162Q1D7K81
Fumarate hydratase class I (EC 4.2.1.2)fumB S3629 SF4101 AJR25_010500Q83MI71
Fumarate hydratase class I, aerobic (EC 4.2.1.2) (Fumarase A) (Oxaloacetate keto--enol-isomerase) (OAAKE isomerase) (Oxaloacetate tautomerase) (EC 5.3.2.2)fumA b1612 JW1604P0AC331
Fumarate hydratase class II (Fumarase C) (EC 4.2.1.2) (Aerobic fumarase) (Iron-independent fumarase)fumC FTN_0220A0Q4G51
Fumarate hydratase class II (Fumarase C) (EC 4.2.1.2) (Aerobic fumarase) (Iron-independent fumarase)fumC fum Rv1098c MTV017.51cP9WN931
Fumarate hydratase class II (Fumarase C) (EC 4.2.1.2) (Aerobic fumarase) (Iron-independent fumarase)fumC SAOUHSC_01983Q2FX941
Fumarate reductase flavoprotein subunit (EC 1.3.5.4)frdA HP_0192O069131
Fumarate reductase flavoprotein subunit (EC 1.3.5.4)frdA HPSD74_2223U4S8M11
Fumarate reductase flavoprotein subunit (EC 1.3.5.4)frdA SCH_4222Q57GN41
Fumarate reductase subunit DfrdD VSAK1_11283A6D8Y11
Fumarate/nitrate reduction transcriptional regulatorVSAK1_11585A6D6D31
FumarylacetoacetaseB195_05221M5R2I81
Fur regulated Salmonella iron transportersitA STM2861Q7CPX81
Fusaric acid resistance protein fusEVSAK1_18022A6CVG51
Fused cysteine transporter subunits of ABC superfamily: membrane component/ATP-binding componentVSAK1_06255A6CZP11
Fused fructose-specific PTS enzymes: IIA component/HPr componentVSAK1_22769A6CVW01
Fused trehalose(Maltose)-specific PTS enzyme: IIB component/IIC componentVSAK1_10523A6D8S21
Fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein (EC 1.1.1.35) (EC 4.2.1.17) (EC 5.1.2.3) (EC 5.3.3.8)acbP fadB FTT_1530Q5NET21
Galactitol 1-phosphate 5-dehydrogenase (EC 1.1.1.251)gatD b2091 JW2075P0A9S31
Galactitol-specific PTS system IIC componentLMRG_02210A0A0H3GFG81
Galactose-1-phosphate uridylyltransferase (EC 2.7.7.12)Fphi_1856B0U1631
Galactose-1-phosphate uridylyltransferase 1 (Gal-1-P uridylyltransferase 1) (EC 2.7.7.12) (UDP-glucose--hexose-1-phosphate uridylyltransferase 1)galT1 spr1648Q8DNL81
Galactose-6-phosphate isomerase subunit LacA 2 (EC 5.3.1.26)lacA2 lacA.2 SPy_1923 M5005_Spy1638Q99Y121
Galactose-6-phosphate isomerase subunit LacB (EC 5.3.1.26)lacB spr1075Q8DPP01
Galactose-6-phosphate isomerase subunit LacB 1 (EC 5.3.1.26)lacB1 lacB.1 SPy_1707 M5005_Spy1397Q99YH21
Galactose-6-phosphate isomerase subunit LacB 2 (EC 5.3.1.26)lacB2 lacB.2 SPy_1922 M5005_Spy1637Q99Y131
Galactose-binding proteinmglB YPO1507Q0WGR51
Galactose-proton symporter, major facilitator superfamily (MFS) transport proteingalP2 FTT_1473cQ5NEY31
Galactose-proton symporter, major facilitator superfamily (MFS) transport proteingalP1 FTT_1474cQ5NEY21
Galactose/methyl galactoside import ATP-binding protein MglA (EC 3.6.3.17)mglA SSON_2205Q3Z0571
Galactose/methyl galactoside import ATP-binding protein MglA (EC 3.6.3.17)mglA VSAK1_25205A6CZ971
Galactosyl transferasewbtP FTN_1429A0Q7T21
Galactosyl transferasewbtB FTT_1463cQ5NEZ21
Galacturonosyl transferase (EC 2.4.1.-)wbtD FTT_1461cQ5NEZ41
GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase (EC 2.4.1.292) (Protein glycosylation H)pglH Cj1129cQ0P9C51
Gamma-carboxygeranoyl-CoA hydrataseB195_07685M5QL641
Gamma-glutamyl kinase (EC 2.7.2.11) (Fragment)VSAK1_02539A6D9Q51
Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)proA Rv2427c MTCY428.20P9WHV11
Gamma-glutamyl phosphate reductase (GPR) (EC 1.2.1.41) (Glutamate-5-semialdehyde dehydrogenase) (Glutamyl-gamma-semialdehyde dehydrogenase) (GSA dehydrogenase)proA SPy_1670 M5005_Spy1370Q99YJ81
Gamma-glutamylcyclotransferase (EC 2.3.2.-)chaC SSON_1959Q3Z0T61
Gamma-glutamyltransferaseB195_17849M5QSA41
Gamma-glutamyltransferaseB195_03927M5QZ491
Gamma-glutamyltransferase (EC 2.3.2.2)Fphi_0050B0TXV11
Gamma-glutamyltransferase (EC 2.3.2.2)ggt HPSD74_0885U4SIG61
GAMMA-GLUTAMYLTRANSPEPTIDASEggt jhp_1046Q9ZK951
Gamma-glutamyltranspeptidaseVS_3081B7VMF71
Gamma-glutamyltranspeptidase (EC 2.3.2.2)ggt FTT_1181cQ5NFP81
Gamma-glutamyltranspeptidase (EC 2.3.2.2) (EC 3.4.19.13)ggt PP_4659Q88E091
Gamma-glutamyltranspeptidase (Ggt)HP_1118O257431
Gamma-hemolysin component ChlgC MW2343Q7A0191
Gas vesicle protein, GvpL/GvpF familyMXAN_2769Q1D8N71
GDP diphosphokinase/guanosine-3',5'-bis(Diphosphate) 3'-diphosphatasespoT FTN_1198A0Q7691
GDP-mannose 4,6-dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase)gmdA gmd Rv1511P717901
GDP-mannose 4,6-dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase)gmd gca PA5453Q513661
GDP-mannose 4,6-dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase)gmd OOM_0777I2AYM81
GDP-mannose 4,6-dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase)gmd yefA yefN b2053 JW2038P0AC881
GDSL-like Lipase/Acylhydrolase family protein (EC 3.1.2.-)FTT_1016cQ5NG411
General L-amino acid ABC transporter periplasmic L-amino acid-binding protein AapJB195_05461M5QZ051
General stress protein 16U (GSP16U)yceD BSU02900P808751
General stress protein 20U (GSP20U) (DPS protein homolog)dps ytkB BSU30650P808791
General stress protein GSP-781gsp-781 spr2021Q8DMY41
GGDEF family proteinVSAK1_20499A6CY771
Gifsy-1 prophage head protein gp7SCH_1220Q57Q851
Gifsy-1 prophage proteinSTM2607Q8ZMZ41
Gingipain R1 (EC 3.4.22.37) (Arg-gingipain)rgpA PGN_1970B2RM931
Gingipain R2 (EC 3.4.22.37) (Arg-gingipain)rgpB PGN_1466B2RKU01
GlnH proteinglnH KPR_3747R4YCM91
Global stress requirement protein GsrAdegP YPO3382Q7CKD31
Glu-tRNAGln amidotransferase C subunitFphi_0914B0TWM91
Glucan 1,4-alpha-glucosidaseDF40_013935A0A064BQ751
Glucans biosynthesis glucosyltransferase H (EC 2.4.1.-)opgH mdoH PP_5025Q88D041
Glucans biosynthesis protein GmdoG opgG B195_02483M5QZK91
Glucans biosynthesis protein GmdoG opgG SSON_1061Q3Z3751
Glucokinase (EC 2.7.1.2)Fphi_0381B0TZP01
Glucokinase (EC 2.7.1.2) (Glucose kinase)glk NMH_1840E6MZG81
Glucokinase (EC 2.7.1.2) (Glucose kinase)glk NMB1390P642541
Glucosamine-6-phosphate deaminase (EC 3.5.99.6) (GlcN6P deaminase) (GNPDA) (Glucosamine-6-phosphate isomerase)nagB VSAK1_20854A6CYE81
Glucosamine-6-phosphate deaminase (EC 3.5.99.6) (GlcN6P deaminase) (GNPDA) (Glucosamine-6-phosphate isomerase)nagB SPy_1399 M5005_Spy1139Q99Z501
Glucose kinase (EC 2.7.1.2)glcK SPy_1529Q99YU91
Glucose kinase (Glucokinase)glk FTN_0462A0Q5501
Glucose-1-phosphataseagp SCH_1067Q57QN81
Glucose-1-phosphatase (G1Pase) (EC 3.1.3.10)agp b1002 JW0987P199261
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) (ADP-glucose pyrophosphorylase) (ADPGlc PPase) (ADP-glucose synthase)glgC MXAN_1524Q1DC471
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) (ADP-glucose pyrophosphorylase) (ADPGlc PPase) (ADP-glucose synthase)glgC Fphi_0326B0TZI31
Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) (ADP-glucose pyrophosphorylase) (ADPGlc PPase) (ADP-glucose synthase)glgC FTN_0515A0Q5951
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