EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
GTPase Der (GTP-binding protein EngA)der HPSD74_0852U4SL401
GTPase Der (GTP-binding protein EngA)der engA pgdA SPy_0341 M5005_Spy0287P640641
GTPase Der (GTP-binding protein EngA)der OOM_0432I2AXR91
GTPase Eraera PA0771Q9XCX81
GTPase Eraera SPy_0476 M5005_Spy0390P0C0B91
GTPase Eraera CD630_24370Q182C31
GTPase Eraera SAOUHSC_01668Q2FY061
GTPase Eraera KU39_1954A0A0K2L4R51
GTPase HflX (GTP-binding protein HflX)hflX SP70585_0731C1C6341
GTPase HflX (GTP-binding protein HflX)hflX MXAN_5229Q1D1U21
GTPase HflX (GTP-binding protein HflX)hflX b4173 JW4131P255191
GTPase HflX (GTP-binding protein HflX)hflX SPy_0922Q9A0581
GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg)obg spr0984Q8DPV81
GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg)obg PA4566Q9HVL81
GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg)obg SSON_3331Q3YX581
GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg)obg SPy_1333 M5005_Spy1088Q99Z941
GTPase Obg (EC 3.6.5.-) (GTP-binding protein Obg)obg SAOUHSC_01753Q2FXT11
GTPase ObgE/CgtA (EC 3.6.5.-) (GTP-binding protein Obg)obgE cgtA obg yhbZ b3183 JW3150P426411
Guanine deaminaseVSAK1_25075A6CZ711
Guanine deaminaseVSAK1_15422A6D7151
Guanine nucleotide exchange factorsopE2 SCH_1852Q57NF31
Guanine nucleotide exchange factor sopE2 (Effector protein sopE2) (Toxin sopE2)sopE2 STM1855Q7CQD41
Guanine/hypoxanthine permease GhxPghxP yjcD b4064 JW4025P0AF521
Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolasespoT PA5338Q9HTM01
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (EC 3.6.1.40) (Guanosine pentaphosphate phosphohydrolase) (pppGpp-5'-phosphohydrolase)gppA VSAK1_24204A6D6I91
Guanylate kinase (EC 2.7.4.8) (GMP kinase)gmk SPy_1632 M5005_Spy1341Q99YM51
HAD hydrolase, IA, variant 1 family proteinKW89_2189A0A0K2DZ701
HAD-superfamily hydrolase, subfamily IA, variant 3Acid_0991Q02AD31
Haemin storage system, HmsF protein (HmsF protein)hmsF YPO1952Q9R7V41
Haemin uptake system outer membrane receptorchuA Cj1614Q0P8141
HAMP domain-containing proteinB195_03048M5QMM91
Head-tail adaptorPP_1570Q88MK11
Heat shock proteinFTT_1794Q5NE641
Heat shock protein 15 (HSP15)hslR yrfH b3400 JW3363P0ACG81
Heat shock protein DnaJ domain-containing proteinNSU_1085G6E9R41
Heat shock protein HtpX (EC 3.4.24.-)htpX FTT_0862cQ5NGH81
Heat shock protein HtpX (EC 3.4.24.84)OOM_0376I2AXM01
Heat shock protein, HSP20 familyFTN_1769A0Q8Q41
Heat-inducible transcription repressor HrcAhrcA spr0453Q8DQW91
Heat-inducible transcription repressor HrcAhrcA SPy_1763 M5005_Spy1500Q99YC71
Heavy metal cation transport ATPaseFTN_0394A0Q4Y21
Heavy metal cation transport ATPase (EC 3.6.3.3)OOM_0380I2AXM41
Helicase/SNF2 domain proteinMXAN_4680Q1D3C71
Hemagglutinin protein HagAhagA PGN_1733B2RLK71
Hemagglutinin, putativePG_0411F5HGU51
Hemagglutinin-like proteinAB237_2463A0A0E1PTY91
Hemagglutinin/hemolysin-related proteinNMB0497Q9K0S71
Hemagglutinin/hemolysin-related proteinNMB0493Q9K0T01
Hemagglutinin/hemolysin-related proteinNMB1768Q9JY301
Heme exporter protein D (Cytochrome c-type biogenesis protein CcmD)ccmD PA1478Q9I3N41
Heme oxygenase (EC 1.14.99.3)CPC_0232B1BH571
Heme receptorVS_II0751B7VS021
Heme transport protein HutAVC_A0576Q9KM131
Heme utilization proteinNMBB_1917E3D1T51
Heme-binding protein FetBPGN_0705B2RIM91
Heme-transporting ATPase (EC 3.6.3.41)ccmA MXAN_3258Q1D7B61
Heme/hemin ABC transporter, periplasmic heme/hemin-binding proteinPP_4689Q88DX91
Heme/hemopexin-binding proteinhxuA HPSD74_2080U4S8Y81
Heme/hemopexin-binding protein AhxuA NTHI0371Q4QNS41
Hemoglobin receptorhmbR NMB1668Q9JYA81
HemolysinethAO326081
HemolysinhlyA VC_A0219P095451
HemolysinEHEC-hlyAQ472621
Hemolysin activation/secretion protein-like proteinNSU_1235G6EA641
Hemolysin secretion/activation ShlB/FhaC/HecB family proteinHPSD74_0813U4SL091
Hemolysin secretion/activation ShlB/FhaC/HecB family proteinHPSD74_0887U4SHP61
Hemolysin, putativeVC_0578Q9KUE31
Hemolysin-related proteinVC_0930Q9KTH21
Hemolysin-related proteinVC_1888Q9KQW01
HemX proteinSC1083_2170G4ABD51
HemYhemY SCH_3836Q57HS01
HemY family proteinHPSD74_1107U4SI751
HemY proteinSC1083_2171G4ABD61
Heparin-binding hemagglutinin (Adhesin)hbhA Rv0475 MTCY20G9.01P9WIP91
Heptaprenyl diphosphate syntase component II, putative (EC 2.5.1.30)SAOUHSC_01486Q2FYG61
Heptosyltransferase IIwaaF PA5012G3XD351
Hexulose-6-phosphate synthase (HumpS) (EC 4.1.2.-)sgh spr1846Q8DN971
HflC proteinSC1083_0588G4A6Z81
HflK proteinSC1083_0409G4A6G91
HflK-HflC membrane protein complex, HflKhflK FTN_1048A0Q6S01
HflK-HflC membrane protein complex, HflKOOM_1329I2AZZ41
High frequency lysogenization protein HflDhflD ycfC b1132 JW5165P257461
High frequency lysogenization protein HflD homologhflD PA2627Q9I0L11
High-affinity branched-chain amino acid transport ATP-binding proteinB195_10961M5QGN11
High-affinity branched-chain amino acid transport ATP-binding protein BraFbraF PP_4864Q88DG11
High-affinity branched-chain amino acid transport ATP-binding protein BraFbraF PA1071P216291
High-affinity branched-chain amino acid transport ATP-binding protein BraGbraG PA1070P216301
High-affinity branched-chain amino acid transport system permease protein LivM (LIV-I protein M)livM b3456 JW3421P227291
High-affinity gluconate transporter (Gluconate permease) (Gnt-I system)gntT gntM usgA yhgC b3415 JW5690P398351
High-affinity zinc uptake system protein ZnuAznuA yebL yzzP b1857 JW5831P391721
High-affinity zinc uptake system protein znuAznuA HPSD74_1084U4SJ191
Highly acidic proteinCj1178cQ0P9781
Hippurate hydrolaseNSU_0174G6E7531
Histidine ammonia-lyase (Histidase) (EC 4.3.1.3)hutH B195_02453M5QNX51
Histidine ammonia-lyase (Histidase) (EC 4.3.1.3)hutH KPR_3791R4YI451
Histidine ammonia-lyase (Histidase) (EC 4.3.1.3)hutH VSAK1_17072A6CUX51
Histidine biosynthesis bifunctional protein HisB [Includes: Histidinol-phosphatase (EC 3.1.3.15); Imidazoleglycerol-phosphate dehydratase (IGPD) (EC 4.2.1.19)]hisB HPSD74_1336U4SFS51
Histidine biosynthesis bifunctional protein HisB [Includes: Histidinol-phosphatase (EC 3.1.3.15); Imidazoleglycerol-phosphate dehydratase (IGPD) (EC 4.2.1.19)]hisB VSAK1_00200A6D5K31
Histidine kinaseVSAK1_06035A6CZJ71
Histidine kinase (EC 2.7.13.3)MXAN_4445Q1D4071
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