EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Hypothetical membrane proteinFTT_0924Q5NGC21
Hypothetical membrane proteinFTT_0956cQ5NG961
Hypothetical membrane proteinFTT_1198cQ5NFN51
Hypothetical membrane proteinFTT_1406cQ5NF421
Hypothetical membrane proteinFTT_1407cQ5NF411
Hypothetical membrane proteinFTT_1495cQ5NEW21
Hypothetical membrane proteinFTT_1496cQ5NEW11
Hypothetical membrane proteinFTT_1525cQ5NET71
Hypothetical membrane proteinFTT_1621cQ5NEK81
Hypothetical membrane proteinFTT_1629cQ5NEK01
Hypothetical membrane proteinFTT_1653Q5NEI11
Hypothetical membrane proteinFTT_1676Q5NEG01
Hypothetical membrane proteinFTT_1777cQ5NE761
Hypothetical membrane proteinFTT_1778cQ5NE751
Hypothetical muconate cycloisomerase IVSAK1_10208A6D0P91
Hypothetical phage proteinYPO2124Q7CIF61
Hypothetical proteiSPy_1840Q99Y711
Hypothetical secretion proteinVSAK1_25905A6D0X11
Hypothetical transcriptional regulatorVSAK1_00597A6D1801
Hypothetical xanthine/uracil permeaseVSAK1_24945A6CZ451
Hypoxanthine phosphoribosyltransferase (EC 2.4.2.8)SAOUHSC_00485Q2G0R11
Hypoxanthine-guanine phosphoribosyltransferaseVSAK1_04730A6D6A91
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) (EC 2.4.2.8)hprT hpt BSU00680P374721
IcmF1icmF1 PA0077Q9I7551
IgA-specific serine endopeptidase (EC 3.4.21.72)NMH_2319E6N0K31
IgA-specific serine endopeptidase (EC 3.4.21.72)iga1 NTHI1164Q4QLS01
Igab-domain of IgA protease (Fragment)0Q064681
ilv operon leader peptide (ilvGMEDA operon attenuator peptide)ilvL b3766 JW3739P625221
Imidazole glycerol phosphate synthase subunit HisF (EC 4.1.3.-) (IGP synthase cyclase subunit) (IGP synthase subunit HisF) (ImGP synthase subunit HisF) (IGPS subunit HisF)hisF VSAK1_00215A6D5K61
Imidazole glycerol phosphate synthase subunit HisH 1 (EC 2.4.2.-) (IGP synthase glutamine amidotransferase subunit 1) (IGP synthase subunit HisH 1) (ImGP synthase subunit HisH 1) (IGPS subunit HisH 1)hisH1 PA5142Q9HU421
Imidazoleglycerol-phosphate dehydratase (IGPD) (EC 4.2.1.19)hisB B195_02216M5QMH31
Imidazoleglycerol-phosphate dehydratase (IGPD) (EC 4.2.1.19)hisB Rv1601 MTCY336.03cP9WML91
Immunogenic proteinVC_0430Q9KUT51
Immunogenic proteinVS_0355B7VIC71
Immunogenic protein MPT63 (16 kDa immunoprotective extracellular protein) (Antigen MPT63)mpt63 Rv1926c MTCY09F9.38P9WIP11
Immunogenic protein MPT64 (Antigen MPT64)mpt64 Rv1980c MTCY39.39P9WIN91
Immunogenic secreted proteinisp SPy_2025Q99XU71
Immunoglobulin A1 protease (IgA1 protease) (EC 3.4.24.13) (IgA-specific zinc metalloproteinase)iga spr1042Q599471
Immunoglobulin A1 protease (IgA1 protease) (EC 3.4.24.13) (IgA-specific zinc metalloproteinase)iga SP_1154Q97QP71
Immunoglobulin-binding protein sbisbi SACOL2418Q5HDD71
Immunoglobulin-binding protein sbisbi SAOUHSC_02706Q2FVK51
Immunoreactive 23 kDa antigenPGN_0336B2RHL01
Immunoreactive 23 kDa antigen PG66PG_0234F5H9H11
Immunoreactive 46 kDa antigenPGN_1767B2RLP11
Immunoreactive 46 kDa antigen PG99PG_1798F5H9F81
Immunoreactive 47 kDa antigenPGN_0852B2RJ261
Immunoreactive 53 kDa antigen PG123PG_2167F5H9B81
Immunoreactive 61 kDa antigenPGN_0152B2RH261
Immunoreactive 63 kDa antigen PG102PG_2100Q7MT801
Immunoreactive 84 kDa antigenPGN_0509B2RI331
Immunoreactive 84 kDa antigen PG93PG_1604F5H8T81
Indole-3-glycerol phosphate synthase (IGPS) (EC 4.1.1.48)trpC spr1634Q8DNM61
Indole-3-glycerol phosphate synthase (IGPS) (PRAI) (EC 4.1.1.48) (EC 5.3.1.24) (N-(5'-phosphoribosyl)anthranilate isomerase)trpC trpF FTN_1770A0Q8Q51
Inducible lysine decarboxylase (LDC) (EC 4.1.1.18)cadA ldcI b4131 JW4092P0A9H31
Inhibitor of cysteine peptidaseicp PA0778Q9I5G01
Inner membrane ABC transporter ATP-binding protein YddA (CDS102)yddA b1496 JW5242P318261
Inner membrane ABC transporter permease protein YcjOycjO b1311 JW1304P0AFR71
Inner membrane efflux transporter CmeB (Multidrug efflux system CmeABC)cmeB Cj0366cQ0PBE41
Inner membrane protein YabIyabI b0065 JW5005P301491
Inner membrane protein YbaNybaN b0468 JW0457P0AAR51
Inner membrane protein YccSyccS b0960 JW5128P758701
Inner membrane protein YcfZycfZ b1121 JW1107P759611
Inner membrane protein YdgCydgC b1607 JW1599P0ACX01
Inner membrane protein YeeRyeeR b2001 JW1983P763611
Inner membrane protein YghQyghQ b2983 JW5490Q468411
Inner membrane protein YgiZygiZ b3027 JW2995Q468671
Inner membrane protein YnbAynbA b1408 JW1405P760901
Inner membrane protein YphAyphA b2543 JW2527P0AD471
Inner membrane transport permease YbhSybhS b0793 JW0777P0AFQ21
Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase)ppa YPO3521 y0663 YP_0562Q8ZB981
Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase)ppa Rv3628 MTCY15C10.24P9WI551
Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase)ppa b4226 JW4185P0A7A91
Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase)ppa Smlt3902B2FT631
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB Fphi_0160B0TYL61
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB NMB1201Q9JZB51
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB Cj1058cQ0P9J41
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB B195_11511M5QGZ41
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB MXAN_3777Q1D5W41
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB HPSD74_0293U4SKL81
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB VSAK1_12015A6D2X91
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB SPy_2206 M5005_Spy1857P0C0H71
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB OOM_1248I2AZS31
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB FSU_3016C9RLM31
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPD) (IMPDH) (EC 1.1.1.205)guaB SAOUHSC_00374Q2G0Y71
Inositol monophosphataseB195_11646M5QHN71
Inositol monophosphatase / glycerol-2-phosphatase (EC 3.1.3.19) (EC 3.1.3.25)suhB PP_0838Q88PL21
Inositol monophosphatase family proteinFTN_1346A0Q7K61
Inositol phosphate phosphatase IpgD (EC 3.1.3.78) (Effector protein IpgD) (Phosphatidylinositol 4,5-bisphosphate 4-phosphatase)ipgD CP0133Q075661
Inositol phosphate phosphatase SopB (EC 3.1.3.-) (Effector protein SopB)sopB sigD STM1091O309161
Inositol-1-monophosphatase (EC 3.1.3.25)SPy_1247Q99ZF91
Inositol-1-monophosphatase (EC 3.1.3.25)suhB FTT_1382Q5NF651
Inositol-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD) (EC 1.1.1.205)guaB CD630_23350Q185K91
Insecticidal toxin-like proteinFSU_1267C9RNI81
Insecticidal toxin-like proteinFSU_1265D9S9U61
Integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex (EC 3.4.24.-)hflK PP_4892Q88DD51
Integrase/recombinaseBV98_002868A0A086P7F81
Integration host factor subunit alpha (IHF-alpha)ihfA himA STM1339P0A1S01
Integration host factor subunit alpha (IHF-alpha)ihfA himA HPSD74_0117U4SQ511
Integration host factor subunit beta (IHF-beta)ihfB himD hip b0912 JW0895P0A6Y11
Integration host factor subunit beta (IHF-beta)ihfB himD SSON_0914Q3Z3K91
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