EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
L-lactate dehydrogenase (EC 1.1.-.-)lldD SC1083_1399G4A9891
L-lactate dehydrogenase (EC 1.1.-.-)lldD SSON_3800Q3YVX01
L-lactate dehydrogenase (EC 1.1.2.3)lldD1 FTT_0303cQ5NHZ01
L-lactate dehydrogenase (L-LDH) (EC 1.1.1.27)ldh SPy_1151 M5005_Spy0873P652591
L-lactate dehydrogenase 2 (L-LDH 2) (EC 1.1.1.27)ldh2 SAOUHSC_02922Q2G1Y51
L-lactate permeaselldP PP_4735Q88DT41
L-lactate permeaselctP ycgC BSU03060P559101
L-lactate permeaseSAOUHSC_00067Q2G1N91
L-ornithine N(5)-monooxygenase (EC 1.14.13.195) (L-ornithine N(5)-hydroxylase) (Ornithine hydroxylase) (L-ornithine N(5)-oxygenase) (Pyoverdin biosynthesis protein A)pvdA pvd-1 PA2386Q515481
L-rhamnose isomerase (EC 5.3.1.14)rhaA RUMGNA_01007A7B0D11
L-serine dehydratasesdaA FTN_0750A0Q5X61
L-serine dehydrataseB195_06340M5QM201
L-serine dehydratase (EC 4.3.1.17)sdaA Cj1624cQ0P8041
L-serine dehydratase alpha subunit (EC 4.3.1.17)sdaA spr0094Q8DRJ01
L-seryl-tRNA(Sec) selenium transferase (EC 2.9.1.1) (Selenocysteine synthase) (Sec synthase) (Selenocysteinyl-tRNA(Sec) synthase)selA PA4808Q9HV011
L-threonine 3-dehydrogenase (TDH) (EC 1.1.1.103)tdh FTN_0625A0Q5K31
L-threonine 3-dehydrogenase (TDH) (EC 1.1.1.103)tdh VSAK1_15137A6D3D91
L-threonine dehydratase (EC 4.3.1.19) (Threonine deaminase)ilvA VSAK1_24560A6D4091
Lactaldehyde dehydrogenase (EC 1.2.1.22) (Aldehyde dehydrogenase A) (Glycolaldehyde dehydrogenase) (EC 1.2.1.21)aldA ald b1415 JW1412P255531
Lactate utilization protein BlutB yvfW BSU34040O070211
Lactoferrin-binding protein ANMH_1457E6MXQ01
Lactoferrin-binding protein A (Iron-regulated outer membrane protein A)lbpA iroA NMB1540Q063791
Lactonizing lipaseMXAN_5522Q1D1081
Lactose phosphotransferase system repressorlacR spr1067Q8DPP71
Lactoylglutathione lyase (EC 4.4.1.5) (Glyoxalase I)gloA1 PA3524Q9HY851
Lantibiotic biosynthesis proteinSPCG_0146B2IRN11
Lantibiotic transport ATP-binding protein SrtFsrtF SPy_1085 M5005_Spy0808P0C0E31
Large conductance mechano-sensitive ion channelmscL spr0915Q8DQ031
Large-conductance mechanosensitive channelmscL AC1_0185B1R7B01
Large-conductance mechanosensitive channelmscL SAOUHSC_01345P688051
Late competence protein ComECLMRG_02949A0A0H3GJ161
Late embryogenesis abundant protein domain proteinMXAN_6787Q1CXG91
LemA family proteinDET1586Q3Z6671
LemA-like proteinFphi_0447B0U0361
LemA-like proteinOOM_0377I2AXM11
LemA-like proteinFTT_0863cQ5NGH71
Leu/Ile/Val/Thr-binding protein (LIVT-BP)livJ livB STM3567P172151
Leucine ABC transporter subunit substrate-binding protein LivKB195_10941M5QY711
Leucine dehydrogenase (LeuDH) (EC 1.4.1.9)yqiT BSU24080P545311
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)leuS Fphi_1752B0U0E81
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)leuS B195_13116M5QZG01
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)leuS YPO2610 y1184 YP_1103Q8ZDF81
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)leuS Rv0041 MTCY21D4.04P9WFV11
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)leuS KPR_3901R4YH521
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)leuS b0642 JW0637P078131
Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS)leuS SPy_0173 M5005_Spy0147Q9A1P01
Leucine-responsive regulatory proteinlrp alsB ihb livR oppI b0889 JW0872P0ACJ01
Leucine-rich repeat domain proteinMXAN_4062Q1D5331
Leucine-specific-binding protein (L-BP) (LS-BP)livK livC STM3564P0A1W61
Leucine/isoleucine/valine transporter ATP-binding subunitlivG B195_10956M5QUT01
Leucyl aminopeptidase (EC 3.4.11.1)Fphi_1677B0TZZ01
LeukotoxinSC1083_1343G4A9351
Lipase 1 (EC 3.1.1.3) (Glycerol ester hydrolase 1)lipA SAOUHSC_03006Q2FUU51
Lipase 2 (EC 3.1.1.3) (Glycerol ester hydrolase 2)lip2 geh MW0297Q8NYC21
Lipase 2 (EC 3.1.1.3) (Glycerol ester hydrolase 2)lip2 geh SAOUHSC_00300Q2G1551
Lipase/acylhydrolase, GDSL familyFSU_3045D9S7Q91
Lipase/acylhydrolase, GDSL familyFSU_2704C9RK201
Lipase/esteraseFphi_1796B0U0S01
Lipid A biosynthesis lauroyltransferase (EC 2.3.1.241) (Kdo(2)-lipid IV(A) lauroyltransferase)lpxL PA3242Q9HYZ81
Lipid A biosynthesis lauroyltransferase (EC 2.3.1.241) (Kdo(2)-lipid IV(A) lauroyltransferase)lpxL VSAK1_26710A6D8V91
Lipid A deacylase (EC 3.1.1.77) (LPS 3-O-deacylase) (Outer membrane enzyme)B195_04796M5R2A41
Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-)msbA PP_4935Q88D921
Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-)msbA HPSD74_1933U4S9A01
Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-)msbA VSAK1_03942A6D8M01
Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-)msbA OOM_0602I2AY671
Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-)msbA b0914 JW0897P607521
Lipid A export ATP-binding/permease protein MsbA (EC 3.6.3.-)msbA valA FTT_0109Q5NIG31
Lipid A palmitoyltransferase PagP (EC 2.3.1.251) (Antimicrobial peptide resistance) (Lipid A acylation protein)pagP STM0628Q8ZR061
Lipid A palmitoyltransferase PagP (EC 2.3.1.251) (Lipid A acylation protein)pagP crcA SFV_0703Q0T6N31
Lipid A-core, surface polymer ligasewaaL SSON_3783Q3YVY61
Lipid II:glycine glycyltransferase (EC 2.3.2.16) (Factor essential for expression of methicillin resistance X)femX fmhB SAOUHSC_02527Q2FVZ41
Lipid III flippasewzxE wzx yifJ b3792 JW3766P0AAA71
Lipid-A-disaccharide synthase (EC 2.4.1.182)lpxB FTT_1568cQ5NEQ21
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168) (Branched-chain alpha-keto acid dehydrogenase complex component E2) (BCKAD-E2) (BCKADE2) (Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex) (Dihydrolipoamide branched chain transacylase) (Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase)bfmBB bfmB bfmB2 BSU24030P379421
Lipoarabinomannan carrier protein LprG (27 kDa lipoprotein) (Antigen P27) (Lipoprotein LprG) (Triacylated glycolipid carrier LprG) (Triacylglyceride transfer protein LprG)lprG lpp-27 Rv1411c MTCY21B4.28cP9WK451
Lipoate--protein ligase (EC 6.3.1.20)SPy_1033Q99ZX31
Lipoate--protein ligase (EC 6.3.1.20)lplA SPy_1214Q99ZI81
Lipolytic enzymeFTN_0436A0Q5241
Lipopolysaccharide biosynthetic protein LpxO1lpxO1 PA4512Q9HVQ91
Lipopolysaccharide export system protein LptAlptA VC_2527Q9KP501
Lipopolysaccharide export system protein LptClptC PP_0955Q88P971
Lipopolysaccharide export system protein LptCyrbK lptC YPO3579Q7CL871
Lipopolysaccharide proteinFTT_0256cQ5NI341
LipoproteinnlpD KPN_03104A6TD341
LipoproteinNMH_1286E6MY461
LipoproteinB195_20330M5QQJ11
LipoproteinB195_19693M5QQK21
LipoproteinB195_19978M5QUI11
LipoproteinB195_19206M5QUM51
LipoproteinB195_19176M5QR841
LipoproteinB195_18401M5QFQ81
LipoproteinB195_17459M5QVN61
LipoproteinB195_10716M5QY221
LipoproteinB195_10996M5QH781
LipoproteinB195_12151M5QJJ91
LipoproteinB195_12241M5QYZ01
LipoproteinB195_08717M5QX041
LipoproteinB195_08872M5QJ351
LipoproteinB195_05900M5QK531
LipoproteinB195_04552M5QZH31
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