EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Membrane-fusion proteinVSAK1_12752A6D8R71
Membrane-spanning inner membrane proteintolQ SSON_0689Q3Z4671
Menaquinone biosynthesis methyltransferase, putative (EC 2.1.1.-)SAOUHSC_01487Q2FYG51
Meromycolate extension acyl carrier protein (ACP)acpM Rv2244 MTCY427.25P9WQF31
Metabolite MFS transporter, MHS familyPP_2569Q88JS81
Metal ion transporterKU39_2473A0A0K2L6501
Metal-dependent exopeptidaseFTN_0965A0Q6I81
Metalloendopeptidase-like membrane proteinB195_11531M5QV451
Metallothionein (MT) (Copper-binding metallothionein) (Cu(I)-binding metallothionein) (Mycobacterial metallothionein)mymT Rv0186AP9WK091
Methanol dehydrogenase regulatory proteinmoxR FTT_0290Q5NI021
Methionine aminopeptidase (MAP) (MetAP) (EC 3.4.11.18) (Peptidase M)map SPCG_1194B2IQ221
Methionine aminopeptidase (MAP) (MetAP) (EC 3.4.11.18) (Peptidase M)map spr0992Q8DPV11
Methionine aminopeptidase (MAP) (MetAP) (EC 3.4.11.18) (Peptidase M)map PA3657Q9HXY11
Methionine aminopeptidase (MAP) (MetAP) (EC 3.4.11.18) (Peptidase M)map SPy_1354Q99Z811
Methionine gamma-lyase (EC 4.4.1.11)B195_09709M5QKT71
Methionine import ATP-binding protein MetN (EC 3.6.3.-)metN spr0149Q8DRF91
Methionine import ATP-binding protein MetN (EC 3.6.3.-)metN yusC BSU32750O321691
Methionine import ATP-binding protein MetN (EC 3.6.3.-)metN Smlt4088B2FHW51
Methionine import ATP-binding protein MetN (EC 3.6.3.-)metN SPy_0320 M5005_Spy0272Q9A1E31
Methionine import ATP-binding protein MetN (EC 3.6.3.-)metN FTT_1124Q5NFU51
Methionine import ATP-binding protein MetN (EC 3.6.3.-)metN LMRG_02587A0A0H3GD631
Methionine import ATP-binding protein MetN 2 (EC 3.6.3.-)metN2 SAOUHSC_00842Q2FZZ21
Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS)metH PA1843Q9I2Q21
Methionine uptake transporter (MUT) family protein, membrane and periplasmic proteinmetlQ FTN_1107A0Q6X81
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG jhp_0967Q9ZKG91
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG FTN_0468A0Q5561
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG YPO1522 y2648 YP_1411Q8ZG011
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG metS Rv1007c MTCI237.24P9WFU51
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG PA3482Q9HYC71
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG b2114 JW2101P009591
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG SSON_2163Q3Z0961
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG metS SPy_0422 M5005_Spy0345Q9A1781
Methionine--tRNA ligase (EC 6.1.1.10) (Methionyl-tRNA synthetase) (MetRS)metG NSU_4326G6EJ051
Methionyl-tRNA formyltransferase (EC 2.1.2.9)fmt PA0018O857321
Methionyl-tRNA formyltransferase (EC 2.1.2.9)fmt SPy_1628 M5005_Spy1338Q99YM71
Methyl accepting chemotaxis protein II, aspartate sensor-receptorcheM SCH_1926Q57N791
Methyl-accepting chemotaxis (MCP) signaling domain proteinKU39_432A0A0K2L0A81
Methyl-accepting chemotaxis (MCP) signaling domain proteinKU39_2078A0A0K2L5211
Methyl-accepting chemotaxis proteinMXAN_1248Q1DCW61
Methyl-accepting chemotaxis proteinAHA_2535A0KL971
Methyl-accepting chemotaxis protein I, serine sensor receptortsr SCH_4385Q57G711
Methyl-accepting chemotaxis protein II (MCP-II) (Aspartate chemoreceptor protein)tar cheM b1886 JW1875P070171
Methyl-accepting chemotaxis protein PctApctA PA4309G3XD241
Methyl-accepting chemotaxis protein signaling domain proteinANACOL_03921B0PGQ31
Methyl-accepting chemotaxis protein TlpAtlpA BSU31250P392161
Methylase of chemotaxis methyl-accepting proteinVSAK1_02929A6CX781
Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase)VSAK1_20474A6CY721
Methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (Fragment)VSAK1_08676A6D9K41
Methylenetetrahydrofolate reductase (EC 1.5.1.20)metF PA0430Q9I6871
Methylenetetrahydrofolate reductase (EC 1.5.1.20)Smlt2582B2FSU81
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO (EC 2.1.1.74) (Folate-dependent tRNA (uracil-5-)-methyltransferase) (Folate-dependent tRNA(M-5-U54)-methyltransferase)trmFO gid spr0844Q8DQ511
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO (EC 2.1.1.74) (Folate-dependent tRNA (uracil-5-)-methyltransferase) (Folate-dependent tRNA(M-5-U54)-methyltransferase)trmFO gid SPy_1173 M5005_Spy0893Q99ZL91
Methylglyoxal synthase (MGS) (EC 4.2.3.3)mgsA VSAK1_14692A6D7E91
Methylisocitrate lyaseKW89_695A0A0K2DUY71
Methylmalonate-semialdehyde dehydrogenaseB195_03882M5QL791
Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109)mtnB PA1683Q9I3421
MethyltransferaseFTN_1158A0Q7291
MetQHPSD74_0537U4SJW11
Mevalonate kinasemvaK1 SPy_0876Q9A0981
Mevalonate pyrophosphate decarboxylasemvaD SPy_0877Q9A0971
MexH family multidrug efflux RND transporter periplasmic adaptor subunitKW89_1262A0A0K2DWK61
MexH family multidrug efflux RND transporter periplasmic adaptor subunitKW89_2927A0A0K2E0T91
MFP transporterKW89_811A0A0K2DVA21
MFS family, sn-glycerol-3-phosphate transport proteinglpT SCH_2286Q57M701
MFS transporterKW89_2094A0A0K2DYX11
Mg-dependent DNaseFTN_1408A0Q7R31
MglB proteinmglB KPR_1505R4YDJ21
MHC class II analog proteinSAOUHSC_02161Q2FWW11
Mini-ribonuclease 3 (Mini-3) (Mini-RNase 3) (EC 3.1.26.-) (Mini-RNase III) (Mini-III)mrnC SPy_1940Q99Y001
Minor extracellular protease vpr (EC 3.4.21.-)vpr BSU38090 ipa-45rP291411
Minor fimbrium anchoring subunit Mfa2 (Minor fimbrial antigen 2)mfa2 PGN_0288B2RHG21
Minor fimbrium subunit Mfa1 (Pg-II fim a)mfa1 PGN_0287B2RHG11
Minor fimbrium subunit Mfa5PGN_0291B2RHG51
Minor fimbrium tip subunit Mfa3mfa3 PGN_0289B2RHG31
Minor fimbrium tip subunit MfA4 (Immunoreactive 32 kDa antigen PG49)mfA4 PG_0181Q7MXK01
Minor fimbrium tip subunit MfA4 (Immunoreactive 32 kDa antigen)PGN_0290B2RHG41
Miropsin-20A0A0F7INH71
MIT family metal ion transporterLMRG_00526A0A0H3GFC21
Mitogenic exotoxin ZsmeZ SPy_1998Q99XW11
Mitogenic factormf SPy_2043Q7DAK91
Mixed type I polyketide synthase-peptide synthetaseMXAN_3933Q1D5G01
MlaCyrbC HPSD74_0859U4SKC51
MltA-interacting MipANSU_1061G6E9P01
MltA-interacting proteinmipA SF1441 S1556P0A9091
MMPL family proteinKW89_3011A0A0K2E1131
MMS1, Mono-functional DNA-alkylating agent methylOOM_0943I2AZ111
Modulator of FtsH protease HflChflC hflA b4175 JW4133P0ABC31
Molybdate ABC transporter periplasmic molybdate-binding proteinLMRG_00502A0A0H3GBM11
Molybdate ABC transporter, ATPase subunitCpha266_0452A1BDN31
Molybdate ABC transporter, molybdate-binding proteinmodA CPC_2335B1BID11
Molybdate ABC transporter, periplasmic molybdate-binding proteinmodA HPSD74_1576U4SFG51
Molybdate-binding periplasmic proteinmodA PP_3828Q88G971
Molybdate-binding periplasmic proteinmodA YPO1145Q0WHQ41
Molybdenum ABC transporter, periplasmic molybdate-binding proteinSAOUHSC_02549Q2FVX41
Molybdenum cofactor biosynthesis protein BmoaB STM0803Q7CQW61
Molybdenum cofactor guanylyltransferase (MoCo guanylyltransferase) (EC 2.7.7.77) (GTP:molybdopterin guanylyltransferase) (Mo-MPT guanylyltransferase) (Molybdopterin guanylyltransferase) (Molybdopterin-guanine dinucleotide synthase) (MGD synthase)mobA VSAK1_26220A6D1341
Molybdenum import ATP-binding protein ModC (EC 3.6.3.29)modC SSON_0717Q3Z4451
Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75)mog mogA jhp_0735Q9ZL451
Molydopterin containing oxidoreductaseCj0005cQ0PCC01
Monofunctional glycosyltransferase (MGT) (EC 2.4.1.129) (Peptidoglycan TGase)mgt SAOUHSC_02012Q93Q231
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