EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
NAD-dependent protein deacylase 1 (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1)cobB1 PA1125Q9I4L01
NAD-glutamate dehydrogenaseB195_15272M5QWU81
NAD-specific glutamate dehydrogenase (EC 1.4.1.2)KW89_2083A0A0K2DYX41
NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2)gluD gudB MW0840Q7A1B91
NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2)gluDP273461
NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2) (Surface-associated protein PGAG1)gdh PGN_1367B2RKJ11
NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2) (Surface-associated protein PGAG1)gdh PG_1232P0C9341
NAD/NADP-dependent betaine aldehyde dehydrogenase (BADH) (EC 1.2.1.8)betB B195_14335M5QI011
NAD/NADP-dependent betaine aldehyde dehydrogenase (BADH) (EC 1.2.1.8)betB PA5373Q9HTJ11
NAD/NADP-dependent betaine aldehyde dehydrogenase (BADH) (EC 1.2.1.8)betB VSAK1_20409A6CY591
NADH dehydrogenasendh FTN_0912A0Q6D51
NADH dehydrogenasendh PA4538Q9HVN91
NADH dehydrogenase (EC 1.12.1.2)OOM_1816I2B1601
NADH dehydrogenase (EC 1.6.99.3) (Alkyl hydroperoxide reductase)ahpF ndh BSU40100P429741
NADH dehydrogenase (Quinone) (EC 1.6.99.5)OOM_0538I2AY111
NADH dehydrogenase I, L subunitMXAN_1082Q1DDD11
NADH dehydrogenase I, M subunitMXAN_1081Q1DDD21
NADH dehydrogenase IIHPSD74_1017U4SI601
NADH dehydrogenase subunit II-related proteinVSAK1_12662A6D7Z01
NADH dehydrogenase, FAD-containing subunit (Fragment)VSAK1_03887A6D9B81
NADH dehydrogenase-like protein MW0823 (EC 1.6.99.-)MW0823Q8NXG01
NADH dehydrogenase-like protein SAOUHSC_00878 (EC 1.6.99.-)SAOUHSC_00878Q2FZV71
NADH Oxidase (EC 1.6.-.-)nox SPy_1150Q99ZN61
NADH oxidoreductase InuoG jhp_1187Q9ZJW11
NADH-dependent butanol dehydrogenase BVSAK1_16152A6CYU81
NADH-quinone oxidoreductase (EC 1.6.5.11)Fphi_0935B0TWQ01
NADH-quinone oxidoreductase (EC 1.6.5.11)nuoG KPR_2033R4Y7F51
NADH-quinone oxidoreductase (EC 1.6.5.11)OOM_0532I2AY051
NADH-quinone oxidoreductase (EC 1.6.5.11)nuoG FTT_0037Q5NIM91
NADH-quinone oxidoreductase subunit A (EC 1.6.5.11) (NADH dehydrogenase I subunit A) (NDH-1 subunit A) (NUO1)nuoA OOM_0527I2AY001
NADH-quinone oxidoreductase subunit A (EC 1.6.5.11) (NADH dehydrogenase I subunit A) (NDH-1 subunit A) (NUO1)nuoA FTT_0031Q5NIN51
NADH-quinone oxidoreductase subunit B (EC 1.6.5.11) (NADH dehydrogenase I subunit B) (NDH-1 subunit B) (NUO2)nuoB b2287 JW5875P0AFC71
NADH-quinone oxidoreductase subunit C (EC 1.6.5.11) (NADH dehydrogenase I subunit C) (NDH-1 subunit C)nuoC MXAN_2730Q1D8S61
NADH-quinone oxidoreductase subunit C (EC 1.6.5.11) (NADH dehydrogenase I subunit C) (NDH-1 subunit C)nuoC OOM_0529I2AY021
NADH-quinone oxidoreductase subunit C (EC 1.6.5.11) (NADH dehydrogenase I subunit C) (NDH-1 subunit C)nuoC FTT_0033Q5NIN31
NADH-quinone oxidoreductase subunit C/D (EC 1.6.5.11) (NADH dehydrogenase I subunit C/D) (NDH-1 subunit C/D)nuoC nuoCD nuoD SCH_2326Q57M301
NADH-quinone oxidoreductase subunit D (EC 1.6.5.11) (NADH dehydrogenase I subunit D) (NDH-1 subunit D)nuoD Smlt3402B2FNX61
NADH-quinone oxidoreductase subunit D (EC 1.6.5.11) (NADH dehydrogenase I subunit D) (NDH-1 subunit D)nuoD FTT_0034Q5NIN21
NADH-quinone oxidoreductase subunit E (EC 1.6.5.11) (NADH dehydrogenase I subunit E) (NDH-1 subunit E)nuoE PA2640Q9I0J81
NADH-quinone oxidoreductase subunit F (EC 1.6.5.11)OOM_0531I2AY041
NADH-quinone oxidoreductase subunit F (EC 1.6.5.11)nuoF FTT_0036Q5NIN01
NADH-quinone oxidoreductase subunit F (EC 1.6.5.11) (NADH dehydrogenase I subunit F) (NDH-1 subunit F) (NUO6)nuoF b2284 JW2279P319791
NADH-quinone oxidoreductase subunit G (EC 1.6.5.11) (NADH dehydrogenase I subunit G) (NDH-1 subunit G) (NUO7)nuoG b2283 JW2278P336021
NADH-quinone oxidoreductase subunit H (EC 1.6.5.11) (NADH dehydrogenase I subunit H) (NDH-1 subunit H)nuoH PP_4125Q88FH11
NADH-quinone oxidoreductase subunit H (EC 1.6.5.11) (NADH dehydrogenase I subunit H) (NDH-1 subunit H)nuoH PA2643Q9I0J51
NADH-quinone oxidoreductase subunit H (EC 1.6.5.11) (NADH dehydrogenase I subunit H) (NDH-1 subunit H)nuoH FTT_0038Q5NIM81
NADH-quinone oxidoreductase subunit I (EC 1.6.5.11) (NADH dehydrogenase I subunit I) (NDH-1 subunit I)nuoI Fphi_0937B0TWQ21
NADH-quinone oxidoreductase subunit I (EC 1.6.5.11) (NADH dehydrogenase I subunit I) (NDH-1 subunit I)nuoI FTN_1672A0Q8G41
NADH-quinone oxidoreductase subunit I (EC 1.6.5.11) (NADH dehydrogenase I subunit I) (NDH-1 subunit I)nuoI OOM_0534I2AY071
NADH-quinone oxidoreductase subunit I (EC 1.6.5.11) (NADH dehydrogenase I subunit I) (NDH-1 subunit I)nuoI FTT_0039Q5NIM71
NADH-quinone oxidoreductase subunit M (EC 1.6.5.11) (NADH dehydrogenase I subunit M) (NDH-1 subunit M)nuoM PA2648Q9I0J01
NADH-quinone oxidoreductase subunit N (EC 1.6.5.11) (NADH dehydrogenase I subunit N) (NDH-1 subunit N)nuoN PP_4131Q88FG51
NADH-quinone oxidoreductase subunit N (EC 1.6.5.11) (NADH dehydrogenase I subunit N) (NDH-1 subunit N)nuoN Smlt3392B2FN931
NADH-quinone oxidoreductase, E subunit (EC 1.6.99.5)nuoE FSU_2664C9RJJ91
NADH:flavin oxidoreductase / NADH oxidase family proteinYPO2379Q74TJ11
NADH:flavin oxidoreductase/NADH oxidaseB195_06140M5QLY01
NADH:ubiquinone oxidoreductase, membrane subunit L (EC 1.6.5.11)nuoL PP_4129Q88FG71
NADP-dependent 3-hydroxy acid dehydrogenase YdfG (L-allo-threonine dehydrogenase) (EC 1.1.1.381) (Malonic semialdehyde reductase) (EC 1.1.1.298)ydfG b1539 JW1532P398311
NADP-dependent 7-alpha-hydroxysteroid dehydrogenaseCP4_3572F8UNN11
NADP-dependent alcohol dehydrogenase C (EC 1.1.1.2)adhC adh Rv3045 MTV012.60P9WQC51
NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40)maeB STM2472Q9ZFV81
NADP-dependent malic enzyme, putativeSAOUHSC_01810Q2FXM51
NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) (7-cyano-7-carbaguanine reductase) (NADPH-dependent nitrile oxidoreductase) (PreQ(0) reductase)queF YPO1034 y3147 YP_2817Q8ZH751
NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) (7-cyano-7-carbaguanine reductase) (NADPH-dependent nitrile oxidoreductase) (PreQ(0) reductase)queF SSON_2951Q3YY621
NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) (7-cyano-7-carbaguanine reductase) (NADPH-dependent nitrile oxidoreductase) (PreQ(0) reductase)queF ykvM BSU13750O316781
NADPH-dependent FMN reductaseFTN_0471A0Q5571
NADPH:quinone reductaseB195_00910M5QQX11
Ndh proteinSC1083_0786G4A7J01
NeuraminidaseSP70585_1731C1C8T01
Neuraminyllactose-binding hemagglutinin (Flagellar sheath adhesin) (N-acetylneuraminyllactose-binding fibrillar hemagglutinin receptor-binding subunit) (NLBH)hpaA jhp_0733Q9ZL471
NgoPII restriction endonuclease family proteinHPSD74_1115U4SIF51
NH(3)-dependent NAD(+) synthetase (EC 6.3.1.5)nadE SPy_1652 M5005_Spy1357Q99YK91
Ni/Fe-hydrogenase B-type cytochrome subunithydC Cj1265cQ0P8Z11
Nickel transport system permease protein NikCnikC b3478 JW3443P0AFA91
Nickel-cobalt-cadmium resistance protein (NccB)HP_0970O256231
Nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1)HPSD74_1862U4SCK71
Nicotinate phosphoribosyltransferasepncB HPSD74_1740U4SBQ21
Nicotinate phosphoribosyltransferase (EC 6.3.4.21)SPy_1653Q99YK81
Nicotinate phosphoribosyltransferase (NAPRTase) (EC 6.3.4.21)pncB NMB1505Q9JYM91
Nicotinate phosphoribosyltransferase 1 (NAPRTase 1) (EC 6.3.4.21)pncB1 PA4919Q9HUP41
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase)nadC Rv1596 MTCY336.08cP9WJJ71
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase)nadC PA4524P308191
Nicotine adenine dinucleotide glycohydrolasenga SPy_0165Q7DAN21
NisKSP70585_1289C1C7K51
Nitrate reductase (EC 1.7.99.4)napA HPSD74_1775U4SCZ81
Nitrate reductase 1, alpha subunitnarG KPN_02214A6TAL91
Nitrate reductase 1, alpha subunitnarG SCH_1758Q57NP71
Nitrate-inducible formate dehydrogenase, beta subunitfdnH PA4811Q9HUZ81
Nitrate/nitrite sensor protein NarX (EC 2.7.13.3)narX narR b1222 JW1213P0AFA21
Nitric oxide reductase subunit C (NOR small subunit) (Nitric oxide reductase cytochrome c subunit)norC PA0523Q596461
Nitrogen regulatory protein (Enzyme IIA-NTR) [Includes: Phosphotransferase enzyme IIA component (EC 2.7.1.-) (PTS system EIIA component)]ptsN PA4464Q9HVV41
Nitroreductase-family proteinCD630_11250Q18AY41
NLP/P60 family proteinPG_0740Q7MW941
NLPA lipoproteinB195_00300M5R4T91
Non-haem iron proteinrrc Cj0012cQ0PCB31
Non-ribosomal peptide synthaseMXAN_4414Q1D4381
Non-ribosomal peptide synthaseMXAN_3634Q1D6A21
Non-ribosomal peptide synthase/polyketide synthaseMXAN_3635Q1D6A11
Non-ribosomal peptide synthetaseMXAN_3636Q1D6A01
Non-ribosomal peptide synthetase/polyketide synthaseMXAN_3779Q1D5W21
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