EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Outer membrane receptor for Fe(III)-coprogenfhuE STM1204Q8ZQ101
Outer membrane receptor for iron-regulated colicin I receptorcirA SSON_2211Q3Z0511
Outer membrane transport family proteinJ582_1061A0A010L5L61
Outer membrane-like proteinNSU_3831G6EHL01
Outer proteinsopB SCH_1043Q57QR21
Outer-membrane lipoprotein carrier proteinlolA NMB0622P570681
Outer-membrane lipoprotein carrier proteinlolA FTN_0293A0Q4N41
Outer-membrane lipoprotein carrier proteinlolA B195_20550M5QBZ11
Outer-membrane lipoprotein carrier proteinlolA STM0961Q8ZQD41
Outer-membrane lipoprotein carrier proteinlolA PP_4003Q88FS91
Outer-membrane lipoprotein carrier proteinlolA HP_0785O254741
Outer-membrane lipoprotein carrier proteinlolA HPSD74_0265U4SLS91
Outer-membrane lipoprotein carrier proteinlolA Smlt2346B2FQY61
Outer-membrane lipoprotein carrier proteinlolA FTT_1636Q5NEJ31
Outer-membrane lipoprotein LolBlolB hemM STM1778P307521
Outer-membrane lipoprotein LolBlolB HPSD74_1908U4SD371
Outer-membrane lipoprotein LolBlolB FTT_0270Q5NI201
Outer-membrane porin D (EC 3.4.21.-)opdN PP_3764Q88GG01
Oxaloacetate decarboxylase, beta subunitVSAK1_07799A6D8451
OxidoreductaseFTN_1049A0Q6S11
Oxidoreductase (Mercury (II) reductase)merA spr1442Q8DP001
Oxidoreductase, 2-nitropropane dioxygenase familyMXAN_2267Q1DA351
Oxidoreductase, short chain dehydrogenase/reductase familyFTN_0634A0Q5L21
Oxidoredutase membrane subunit, NrfD familyMXAN_6080Q1CZF81
Oxoglutarate dehydrogenase (Succinyl-transferring) (EC 1.2.4.2)Fphi_0973B0TWT81
Oxygen-dependent choline dehydrogenase (CDH) (CHD) (EC 1.1.99.1) (Betaine aldehyde dehydrogenase) (BADH) (EC 1.2.1.8)betA SAOUHSC_02932Q2FV111
Oxygen-dependent coproporphyrinogen-III oxidase (CPO) (Coprogen oxidase) (Coproporphyrinogenase) (EC 1.3.3.3)hemF VSAK1_24360A6D3W91
Oxygen-insensitive NADPH nitroreductase (EC 1.-.-.-)rdxA HP_0954O256081
OxyRoxyR PA5344Q9HTL41
p-pantothenate cysteine ligase/P-pantothenoylcysteine decarboxylaseFphi_1904B0U1A91
p-pantothenate cysteine ligase/P-pantothenoylcysteine decarboxylasedfp FTN_1128A0Q6Z91
P-protein [Includes: Chorismate mutase (CM) (EC 5.4.99.5); Prephenate dehydratase (PDT) (EC 4.2.1.51)]pheA PA3166Q9HZ671
p-type ATPase-calcium transporter (EC 3.6.3.10)pacL spr1410Q8DP201
p-type conjugative transfer protein VirB9F899_03074N9N7371
p2 proteinFSU_0381C9RQE31
P21 prophage-derived major head protein (Head protein gp7)c1575P686491
p4 lipoproteinSC1083_1947G4AAS11
Pantothenate kinase (EC 2.7.1.33) (Pantothenic acid kinase)coaA SPy_1233 M5005_Spy0945Q99ZH11
Pantothenate synthetase (PS) (EC 6.3.2.1) (Pantoate--beta-alanine ligase) (Pantoate-activating enzyme)panC A1S_0587A3M2941
Pantothenate synthetase (PS) (EC 6.3.2.1) (Pantoate--beta-alanine ligase) (Pantoate-activating enzyme)panC PA4730Q9HV691
Pantothenate synthetase (PS) (EC 6.3.2.1) (Pantoate--beta-alanine ligase) (Pantoate-activating enzyme)panC b0133 JW0129P316631
Pantothenate synthetase (PS) (EC 6.3.2.1) (Pantoate--beta-alanine ligase) (Pantoate-activating enzyme)panC VSAK1_05035A6D3301
PAP2 family proteinMXAN_2614Q1D9401
ParA family proteinVSAK1_19629A6CWK61
Paral putative membrane proteinybjY SCH_0896Q57R591
Paral putative periplasmic proteinyraP SCH_3208Q57JJ81
ParB family proteinVSAK1_24635A6D4241
PASMDG893_17197A6F5Q51
Patatin-like phospholipase family proteinMXAN_3780Q1D5W11
Patatin-like phospholipase family proteinMXAN_4295Q1D4F31
Pathogenicity determinant protein pdpA1OOM_0944I2AZ121
PblBSPJ_1850C1CGE71
PBS lyase HEAT-like repeat proteinMXAN_1397Q1DCG91
PDZ domain proteinAC1_3062B1R5Z71
Pectinesterase (EC 3.1.1.11)ybhC KPN_00791A6T6K61
Pectinesterase (EC 3.1.1.11)FSU_1115C9RMR31
PelCpelC PA3062Q9HZE61
Penicillin binding protein (Peptidoglycan synthetase) (EC 2.4.1.129)ftsI FTT_0697Q5NGX91
Penicillin-binding protein (D-alanyl-D-alanine carboxypeptidase)dacA SPy_0292Q9A1G01
Penicillin-binding protein 1SAOUHSC_01145Q2FZ941
Penicillin-binding protein 1ASC1083_0089G4A5K41
Penicillin-binding protein 1AVSAK1_09403A6D0C11
Penicillin-binding protein 1A (EC 3.4.-.-)mrcA HPSD74_2203U4S8K11
Penicillin-binding protein 1A (PBP-1a) (PBP1a) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.1.129) (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]mrcA ponA NMB1807P0A0Z61
Penicillin-binding protein 1A/1BponA SAMEA3374989_01992 SAMEA3375059_01849A0A1R2F1N41
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase)B195_04547M5QNU41
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase)mrcB PP_4683Q88DY51
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase)mrcB Smlt3681B2FR431
Penicillin-binding protein 2SAOUHSC_01467Q2FYI01
Penicillin-binding protein 2a (EC 2.3.2.-) (EC 2.4.1.129)pbp2a spr1823Q8DNB61
Penicillin-binding protein 3SAOUHSC_01652Q2FY211
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA KPN78578_35260 KPN_03555A6TEG61
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA VC_0581Q9KUE01
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA VS_0439B7VIZ31
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA YPO3548Q0WBA31
Penicillin-binding protein activator LpoA (PBP activator LpoA)yraM lpoA S3405 SF3188 AJR25_007355 AJR27_007790Q83Q191
Penicillin-binding protein activator LpoA (PBP activator LpoA)lpoA SC1083_0783G4A7I71
Penicillin-binding protein activator LpoA (PBP activator LpoA)yraM lpoA SCH_3205Q57JK11
Penicillin-binding protein activator LpoB (PBP activator LpoB)lpoB KPN78578_10740 KPN_01102A6T7G41
Penicillin-binding protein activator LpoB (PBP activator LpoB)lpoB STM1207Q8ZQ081
Penicillin-binding protein, 1A familyCPC_2211B1BIQ01
Penicillin-insensitive murein endopeptidase (EC 3.4.24.-) (D-alanyl-D-alanine-endopeptidase) (DD-endopeptidase)mepA SSON_2386Q3YZN31
Penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase (EC 2.4.2.-) (EC 3.4.-.-)mrcA PP_5084Q88CU61
Pentapeptide repeat domain proteinFSU_0746D9S7Y41
Pentapeptide repeat-containing proteinNSU_3725G6EHA41
PepD proteinpepD KPR_1176R4Y6001
Peptidase (EC 3.4.-.-)FTT_1746Q5NEA21
Peptidase (EC 3.4.15.6)OOM_1628I2B0Q51
Peptidase B (EC 3.4.11.23) (Aminopeptidase B)pepB YPO2889 y1342 YP_2566P584751
Peptidase B (EC 3.4.11.23) (Aminopeptidase B)pepB SSON_2605Q3YZ291
Peptidase family S49 protein (EC 3.4.-.-)sohB FTT_0459Q5NHJ51
Peptidase family U7 protein (EC 3.4.21.-)sohB YPO2216Q7CIM01
Peptidase M13 family proteinHPSD74_2176U4SAA91
Peptidase M16 domain proteinFSU_1453D9SAB31
Peptidase M16 domain-containing proteinNSU_0663G6E8J21
Peptidase M28NSU_0900G6E9791
Peptidase M28NSU_4173G6EIK21
Peptidase M48 family proteinHPSD74_1520U4SHA01
Peptidase PmbAVSAK1_01909A6D4C11
Peptidase S1C, DoB195_06320M5QXS31
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