EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Peptidase S45, penicillin amidaseB195_11081M5QUW21
Peptidase S49 family proteinHPSD74_1977U4SA061
Peptidase T (EC 3.4.11.4) (Aminotripeptidase) (Tripeptidase) (Tripeptide aminopeptidase)pepT SPy_0799 M5005_Spy0614Q9A0F41
Peptidase, M1 (Aminopeptidase N) family (EC 3.4.11.-)MXAN_0644Q1DEL11
Peptidase, M16 (Pitrilysin) family (EC 3.4.24.-)MXAN_1141Q1DD721
Peptidase, M16 (Pitrilysin) family (EC 3.4.24.-)MXAN_2091Q1DAK31
Peptidase, M16 familyFSU_1159D9S9L11
Peptidase, M16 family (EC 3.4.24.-)ACINWC136_2908K9CBG91
Peptidase, M23 familyEDWATA_00569D4F1H91
Peptidase, M24 family protein (EC 3.4.-.-)FTT_0609Q5NH621
Peptidase, M3 (Thimet oligopeptidase) family (EC 3.4.-.-)MXAN_7104Q1CWK61
Peptidase, M36 (Fungalysin) family (EC 3.4.24.-)MXAN_6145Q1CZ971
Peptidase, M36 (Fungalysin) family (EC 3.4.24.-)MXAN_5454Q1D1761
Peptidase, M48 family (EC 3.4.24.-)PFL_5124Q4K6D01
Peptidase, M48 family proteinB195_12211M5QHD71
Peptidase, S8A (Subtilisin) subfamily (EC 3.4.21.-)MXAN_3285Q1D7891
Peptidase, S8A (Subtilisin) subfamily (EC 3.4.21.-)MXAN_0998Q1DDL41
Peptidase, S9A (Prolyl oligopeptidase) family (EC 3.4.21.-)MXAN_3129Q1D7P11
Peptidase, U32 family (EC 3.4.-.-)MXAN_5839Q1D0471
Peptidase, U61 familyFTN_1613A0Q8A81
Peptide ABC transporter, ATP-binding proteinVSAK1_12835A6D2561
Peptide ABC transporter, peptide-binding protein, putativeSAOUHSC_02767Q2FVE71
Peptide ABC transporter, permease componentVSAK1_12845A6D2581
Peptide ABC transporter, permease proteinVSAK1_12850A6D2591
Peptide chain release factor 1 (Fragment)prfA VSAK1_02094A6D9831
Peptide chain release factor 1 (RF-1)prfA prf1 PA4665P428061
Peptide chain release factor 1 (RF-1)prfA SPy_1141 M5005_Spy0863Q99ZP51
Peptide chain release factor 2VSAK1_11188A6D8T81
Peptide chain release factor 2 (RF-2)prfB SPy_0643Q9A0S51
Peptide chain release factor 3 (RF-3)prfC SPy_1416 M5005_Spy1155P660211
Peptide chain release factor RF3 (RF-3)prfC miaD tos b4375 JW5873P0A7I41
Peptide deformylase (EC 3.5.1.88)fms SPy_0870Q9A0A31
Peptide deformylase (PDF) (EC 3.5.1.88) (Polypeptide deformylase)def fms STM3406Q8ZLM71
Peptide deformylase (PDF) (EC 3.5.1.88) (Polypeptide deformylase)def SSON_3427Q3YWX31
Peptide deformylase (PDF) (EC 3.5.1.88) (Polypeptide deformylase)def SPy_1958 M5005_Spy1669P687711
Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)msrA B195_02833M5QZS01
Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)msrA PA5018Q9HUF11
Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)msrA msrA.2 SPy_0466 M5005_Spy0382Q9A1491
Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)msrA NSU_1218G6EA471
Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)msrA OOM_1832I2B1731
Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase)msrA2 msrA FTT_1797cQ5NE611
Peptide methionine sulfoxide reductase MsrA/MsrB [Includes: Peptide methionine sulfoxide reductase MsrA (Protein-methionine-S-oxide reductase) (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase); Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) (Peptide-methionine (R)-S-oxide reductase)]msrAB msrA jhp_0210Q9ZMK81
Peptide methionine sulfoxide reductase MsrB (EC 1.8.4.12) (Peptide-methionine (R)-S-oxide reductase)msrB pilB SAOUHSC_01431P0A0881
Peptide methionine sulfoxide reductase-related protein (EC 1.8.4.11)Fphi_0433B0U0221
Peptide-methionine (R)-S-oxide reductase (EC 1.8.4.12)msrB FTT_0878cQ5NGG41
Peptide/opine/nickel uptake transporter (PepT) family proteinoppF FTN_1589A0Q8841
Peptidoglycan associated lipoprotein (Omp18)HP_1125O257501
Peptidoglycan D,D-transpeptidase MrdA (EC 3.4.16.4) (Penicillin-binding protein 2) (PBP-2)mrdA KU39_2777A0A0K2L7191
Peptidoglycan DD transpeptidase (EC 3.4.-.-) (EC 3.4.16.4)ftsI PP_1331Q88N821
Peptidoglycan hydrolase FlgJ (EC 3.2.1.-) (Muramidase FlgJ)flgJ fla FX flaZ STM1182P159311
Peptidoglycan-associated lipoproteinpal EDWATA_03034D4F8E11
Peptidoglycan-associated lipoproteinpal KPN_00745A6T6G71
Peptidoglycan-associated lipoproteinB195_07305M5R1Y41
Peptidoglycan-associated lipoproteinVC_1835Q9KR121
Peptidoglycan-associated lipoproteinpal SF0556 S0569P0A9141
Peptidoglycan-associated lipoproteinSC1083_1319G4A9131
Peptidoglycan-associated lipoproteinFTT_0842Q5NGJ51
Peptidoglycan-associated lipoprotein PalexcC YPO1125Q7CH551
Peptidoglycan-associated lipoprotein, OmpA familyFphi_0466B0U0551
Peptidoglycan-associated outer membrane lipoproteinexcC ETAE_2572D0ZBT91
Peptidoglycan-associated proteinNSU_1018G6E9J71
Peptidoglycan-N-acetylglucosamine deacetylase (Peptidoglycan GlcNAc deacetylase) (EC 3.5.1.104) (Peptidoglycan N-deacetylase) (PG N-deacetylase)pgdA spr1333Q8DP631
Peptidyl-dipeptidase ANSU_0245G6E7B01
Peptidyl-dipeptidase A (EC 3.4.15.1)MXAN_3581Q1D6F21
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)Fphi_1696B0U0911
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)fkpA KPN_03732A6TEY51
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)B195_20128M5QUL11
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)fkpA PG_0709Q7MWC01
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)fkpA STM3453Q8ZLL61
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)fkpA YPO0195Q0WKB11
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)fkpA S4397 SF3365 AJR25_012915 AJR27_001375Q83JB91
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)slyD HPSD74_1244U4SIR81
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)VSAK1_15372A6D7051
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)OOM_1806I2B1531
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)OOM_0973I2AZ401
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)fklB FSU_1985D9SBK91
Peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8)FTT_1043Q5NG161
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)ppiA KPN_03749A6TF021
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)VC_2299Q9KPR71
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)ppiA spr0679Q8DQG51
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)ppiB PP_2903Q88IU61
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)ppiA YPO0167Q0WKD51
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)SC1083_1624G4A9V51
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)VSAK1_04307A6D6921
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)NSU_0053G6E6T21
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin A) (Rotamase A)ppiA rot rotA b3363 JW3326P0AFL31
Peptidyl-prolyl cis-trans isomerase A (PPIase A) (EC 5.2.1.8) (Cyclophilin) (Rotamase A)ppiA Rv0009 MTCY10H4.08P9WHW31
Peptidyl-prolyl cis-trans isomerase, cyclophilin-typePG_1226Q7MV651
Peptidyl-prolyl cis-trans isomerase-related proteinNMB1238Q9JZ911
Peptidyl-prolyl cis-trans isomerse D (Fragment)VSAK1_02444A6D8D91
Peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29)pth b1204 JW1195P0A7D11
Peptidyl-tRNA hydrolase (PTH) (EC 3.1.1.29)pth SPy_0007 M5005_Spy0005Q9A2061
Peptidylprolyl isomerase (EC 5.2.1.8)Fphi_1852B0U1611
Peptidylprolyl isomerase (EC 5.2.1.8)SC1083_1721G4AA481
Peptidylprolyl isomerase (EC 5.2.1.8)HPSD74_1069U4SJV61
Peptidylprolyl isomerase (EC 5.2.1.8)ybaU ECs0495 Z0548Q8XE551
Peptidylprolyl isomerase (EC 5.2.1.8)prsA1 CD630_35000Q180Z81
Peptidylprolyl isomerase (EC 5.2.1.8)CD196_2119A0A0H3N3M11
Peptidylprolyl isomerase (EC 5.2.1.8)CD630_15570Q18C771
Peptidylprolyl isomerase (EC 5.2.1.8)FSU_0239C9RPM21
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