EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Phosphoglucosamine mutase (EC 5.4.2.10)glmM OOM_0574I2AY451
Phosphoglycerate kinase (EC 2.7.2.3)pgk FTN_1331A0Q7J11
Phosphoglycerate kinase (EC 2.7.2.3)pgk CPR_1300Q0STD51
Phosphoglycerate kinase (EC 2.7.2.3)pgk STM3069P657021
Phosphoglycerate kinase (EC 2.7.2.3)pgk YPO0921 y3308 YP_3519Q8ZHH31
Phosphoglycerate kinase (EC 2.7.2.3)pgk SC1083_1544G4A9M51
Phosphoglycerate kinase (EC 2.7.2.3)pgk b2926 JW2893P0A7991
Phosphoglycerate kinase (EC 2.7.2.3)pgk SFV_2972Q0T0X41
Phosphoglycerate kinase (EC 2.7.2.3)pgk SPy_1881 M5005_Spy1599P688971
Phosphoglycerate kinase (EC 2.7.2.3)pgk CD630_31730Q181T81
Phosphoglycerate kinase (EC 2.7.2.3)pgk SCH_3011Q57K451
Phosphoglycerate kinase (EC 2.7.2.3)pgk FTT_1367cQ5NF761
Phosphoglycerate mutase domain proteinFSU_2641C9RJI11
Phosphoglycerate mutase family proteinFSU_2082C9RRK41
Phosphoglycerate transport: outer membrane protein EpgtE SCH_2396Q57LW01
Phosphoheptose isomerase (EC 5.-.-.-)lpcA FTT_1681cQ5NEF51
Phosphoheptose isomerase (EC 5.3.1.28) (Sedoheptulose 7-phosphate isomerase)gmhA lpcA NMB2090P0A0Y61
Phosphoheptose isomerase (EC 5.3.1.28) (Sedoheptulose 7-phosphate isomerase)gmhA lpcA YPO3243 y0947 YP_0689Q8ZBY71
Phosphoheptose isomerase (EC 5.3.1.28) (Sedoheptulose 7-phosphate isomerase)gmhA VSAK1_07339A6D3E51
Phosphohexosemutasejhp_1196Q9ZJV21
Phospholipase A1 (EC 3.1.1.32) (EC 3.1.1.4) (Detergent-resistant phospholipase A) (DR-phospholipase A) (Outer membrane phospholipase A) (OM PLA) (OMPLA) (Phosphatidylcholine 1-acylhydrolase)pldA b3821 JW3794P0A9211
Phospholipase A1 (EC 3.1.1.32) (EC 3.1.1.4) (Detergent-resistant phospholipase A) (DR-phospholipase A) (Outer membrane phospholipase A) (OM PLA) (OMPLA) (Phosphatidylcholine 1-acylhydrolase)pldA SF3899 S3856P0A9231
Phospholipase D family protein (EC 3.1.1.-)FTT_0490cQ5NHG41
Phospholipid ABC transportermlaE PP_0959Q88P931
PhosphomannomutaseVSAK1_21279A6CZQ01
PhosphomannomutaseVSAK1_09608A6D0G21
Phosphomevalonate kinasemvaK2 SPy_0878Q9A0961
Phosphonate ABC transporter, substrate-binding protein, putativeSAOUHSC_00105Q2G1L71
Phosphonate uptake transporterVSAK1_00787A6D1B81
Phosphonates import ATP-binding protein PhnC (EC 3.6.3.28)phnC VSAK1_20089A6CWU81
Phosphonates import ATP-binding protein PhnC (EC 3.6.3.28)phnC VSAK1_00777A6D1B61
Phosphonates transport ATP-binding proteinphnK VSAK1_19829A6CWP61
Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT)coaD PA0363Q9I6D11
Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT)coaD VSAK1_09703A6D0I11
Phosphopantetheine adenylyltransferase (EC 2.7.7.3) (Dephospho-CoA pyrophosphorylase) (Pantetheine-phosphate adenylyltransferase) (PPAT)coaD kdtB SPy_1537 M5005_Spy1267P638211
Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)deoB FTN_1602A0Q8971
Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)deoB spr0732Q8DQD01
Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)deoB SFV_4417Q0SX281
Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)deoB SPy_0890 M5005_Spy0696P639271
Phosphopentomutase (EC 5.4.2.7) (Phosphodeoxyribomutase)deoB OOM_0606I2AY711
Phosphoporin PhoE (Putative outer membrane porin protein C precurser)nmpC S2073 SF1977 AJR25_008510 AJR27_008620Q83KN41
Phosphoribosyl-AMP cyclohydrolase (PRA-CH) (EC 3.5.4.19)hisI LMRG_00244A0A0H3GDW21
Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase)purD PA4855Q9HUV81
Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase)purD VSAK1_13473A6D4I61
Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (GARS) (Glycinamide ribonucleotide synthetase) (Phosphoribosylglycinamide synthetase)purD SPy_0032 M5005_Spy0029Q9A1Y71
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase)purC SSON_2557Q3YZ761
Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) (SAICAR synthetase)purC VSAK1_06165A6CZM31
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)purM NMB1252Q9JZ801
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)purM PA0945Q9I5131
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)purM HPSD74_1092U4SJ871
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)purM VSAK1_07354A6D3E81
Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase)purM FSU_1946C9RR831
Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT)purL Fphi_0905B0TWM01
Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT)purL FTN_1699A0Q8J11
Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT)purL B195_05590M5QJD21
Phosphoribosylformylglycinamidine synthase (FGAM synthase) (FGAMS) (EC 6.3.5.3) (Formylglycinamide ribonucleotide amidotransferase) (FGAR amidotransferase) (FGAR-AT)purL PP_1037Q88P161
Phosphorylase family proteinACIN5021_0831L9M6161
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)serC Fphi_1843B0U1521
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)serC FTN_0955A0Q6H81
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)serC YPO1389 y2784 YP_1204Q8ZGB41
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)serC PG_1278Q7MV301
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)serC Rv0884c MTCY31.12cP9WQ731
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)serC FSU_1007C9RM311
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)serC Cj0326Q9PIH31
Phosphothreonine lyase OspF (EC 4.2.3.-) (Effector protein OspF)ospF mkaD SSON_P009Q3YTY31
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)VSAK1_00587A6D1781
Phosphotransferase system sugar-specific EII componentPTS-EII spr1969Q8DN201
Phosphotransferase system sugar-specific EII component (EC 2.7.1.69)PTS-EII spr0425Q8DQZ01
Phosphotransferase system sugar-specific EIID componentPTS-EIID spr0062Q8DRL11
Phosphotransferase system transporter enzyme I, FruIfruI PA3562Q9HY551
Phosphotransferase system, fructose-specific IIC componentVSAK1_22759A6CVV81
Phosphotransferase system, mannose-specific EIID (EC 2.7.1.69)manN spr0259Q8DR991
PilApilAQ93PL81
PilCpilCP720831
PilC2 proteinpilC2O059251
PilD-dependent protein pddAxcpT SAMEA3374989_03389 SAMEA3375059_03068A0A160X4221
PilF proteinpilFQ515261
Pilin glycosylation proteinNMBB_2078E3D2E01
Pilin proteinCDIF1296T_02416A0A125V7971
PilO protein (Pilus assembly protein, PilO)pilO PAERUG_E15_London_28_01_14_03389 PAERUG_P32_London_17_VIM_2_10_11_01500Q513531
PilS cassetteNMB0026Q4W5851
PilS cassetteNMB0019Q4W5921
PilS2 (Sensor histidine kinase)pilS2 MXAN_5778Q306N81
Pimeloyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) (Biotin synthesis protein BioH) (Carboxylesterase BioH)bioH KPN78578_37450 KPN_03782A6TF351
PIN/TRAM domain proteinCPC_2773B1BK221
Plasmid addiction system poison proteinSPJ_0034C1CHA71
PLD-like domain proteinKW89_2208A0A0K2DZA31
PmrB: two-component regulator system signal sensor kinase PmrBpmrB PA4777Q9HV311
Pneumococcal histidine triad protein DphtD spr0907Q8DQ081
Pneumococcal histidine triad protein EphtE spr0908Q8DQ071
Pneumococcal vaccine antigen ApvaA spr0930Q8DPY91
Pneumococcal vaccine antigen A homologpvaA SPy_1147 M5005_Spy0869Q99ZN91
Polar amino acid transport system substrate-binding proteinLMRG_02533A0A0H3GKX31
Polar flagellar hook-length control protein FliKVS_0828B7VL101
Poly(3-hydroxyalkanoic acid) synthase 1phaC1 PA5056G3XCV51
Poly(A) polymerase I (PAP I) (EC 2.7.7.19)pcnB PA4727Q9HV721
Polyamine ABC transporter, periplasmic polyamine-binding proteinPP_0412Q88QS61
Polyamine transport protein PotHspuG PA0303Q9I6I81
Polyamine transport protein PotIspuH PA0304Q9I6I71
Polyamine-transporting ATPase (EC 3.6.3.31)potG FTN_0739A0Q5W51
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