EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Polyamine-transporting ATPase (EC 3.6.3.31)spuF PP_5179Q88CK11
Polyamine-transporting ATPase (EC 3.6.3.31)NGK_0322B4RJL21
Polyamine-transporting ATPase (EC 3.6.3.31)OOM_1267I2AZU01
Polyhydroxyalkanoate granule-associated protein GA2PP_5007Q88D211
Polyketide synthaseMXAN_3936Q1D5F71
Polyketide synthaseMXAN_3932Q1D5G11
Polyketide synthaseMXAN_4527Q1D3S81
Polyketide synthaseMXAN_3941Q1D5F21
Polyketide synthase Pks13pks13 Rv3800cI6X8D21
Polyketide synthase type IMXAN_4530Q1D3S51
Polyketide synthase type IMXAN_4529Q1D3S61
Polypeptide-transport-associated domain proteinETAE_2009D0Z8U71
Polyphosphate kinase (EC 2.7.4.1) (ATP-polyphosphate phosphotransferase) (Polyphosphoric acid kinase)ppk A1S_0990A3M3C81
Polyprenyl synthase family proteinMXAN_3678Q1D6581
Polyprenyl synthetase (EC 2.5.1.-)Cj0541Q0PAX51
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp A1S_0361A3M1M71
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp Fphi_0232B0TZ091
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp ETAE_0409D0ZB781
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp PSPTO_4486Q87WQ81
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp ABSDF3154B0VLR71
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp B195_04422M5QNS31
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp spr0516Q8DQT01
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp STM3282Q8ZLT31
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp PP_4708Q88DW01
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp YPO3490 y0694 YP_0593Q0WBF91
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp SF3205 S3422Q83JG01
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp NGK_0489B4RK291
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp Rv2783cP9WI571
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp SC1083_1696G4AA231
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp KPR_4767R4YIY41
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp b3164 JW5851P050551
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp SFV_3194Q0T0B71
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp HPSD74_0572U4SLZ41
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp Smlt3385B2FN861
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp SPy_1946 M5005_Spy1660Q99XZ51
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp OOM_1186I2AZL71
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp pnpA SAOUHSC_01251Q2FZ201
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp KW89_255A0A0K2DTP81
Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) (Polynucleotide phosphorylase) (PNPase)pnp FTT_0699Q5NGX71
Polysaccharide biosynthesis family proteinKW89_2967A0A0K2E0X21
Polysaccharide biosynthesis proteinB195_20760M5QCC51
Polysaccharide biosynthesis proteinCDIF1296T_02916A0A125V8P81
Polysaccharide biosynthesis proteinKU39_110A0A0K2KZE41
Polysaccharide biosynthesis protein, putativeSAOUHSC_01871Q2FXH61
Polysaccharide biosynthesis/export proteinFSU_1216C9RND91
Polysaccharide deacetylase family proteinCPC_0396B1BGK41
Polysaccharide deacetylase family proteinAC1_0976B1R4L81
Polysaccharide deacetylase family proteinCPC_1788B1BGB81
Polysaccharide deacetylase family proteinAC1_2010B1R4W81
Polysaccharide deacetylase family proteinFSU_2304C9RS601
Polysaccharide export proteinNSU_0204G6E7691
Por secretion system protein porQporQ PGN_0645B2RIG91
Por secretion system protein porV (Pg27, lptO)porV PGN_0023B2RGP71
PorA class 1 protein (Fragment)porAO879101
PorinABSDF0595B0VRI01
PorinB195_11391M5QYG31
PorinB195_06465M5QM601
PorinB195_07165M5QMJ01
PorinNSU_3355G6EG841
Porin (Fragment)porB1aA5HM771
Porin IA protein (Fragment)0D0V9T91
Porin P (Outer membrane protein D1)oprP PA3279P056951
Porin, putativeVC_1854Q9KQZ31
Positive transcriptional regulator of glucosyltransferase and Spp phenotypergg spr1933Q8DN441
Possible abortive infection phage resistance proteinabiR SPy_0035Q9A1Y41
Possible arylsulfatase AtsA (Aryl-sulfate sulphohydrolase) (Arylsulphatase)atsA Rv0711P950591
Possible beta-1,3-glucanaseRv0315O072421
Possible conserved exported proteinRv0309O072361
Possible enoyl-CoA hydratase EchA21 (Enoyl hydrase) (Unsaturated acyl-CoA hydratase) (Crotonase)echA21 Rv3774P750191
Possible enoyl-CoA hydratase EchA4 (Enoyl hydrase) (Unsaturated acyl-CoA hydratase) (Crotonase)echA4 Rv0673I6Y8F21
Possible exported alanine and valine rich proteinRv2668P719651
Possible flavoproteinRv2251L0TBR21
Possible hydrolaseRv3591cI6YGL11
Possible iron-regulated short-chain dehydrogenase/reductaseRv3224O058421
Possible ketoacyl reductaseRv1544Q107821
Possible oxidoreductaseRv0063O536081
Potassium efflux protein KefASC1083_0660G4A7691
Potassium uptake proteinKW89_952A0A0K2DVP11
Potassium uptake protein TrkAtrkA FTT_0969cQ5NG841
Potassium-transporting ATPase potassium-binding subunit (ATP phosphohydrolase [potassium-transporting] A chain) (Potassium-binding and translocating subunit A) (Potassium-translocating ATPase A chain)kdpA AC3_1331B1BVA31
PPE family protein PPE41PPE41 Rv2430c LH57_13290Q79FE11
PQQ enzyme repeat domain proteinMXAN_3768Q1D5X31
PqsCpqsC PA0998Q9I4X11
Predicted ATPaseVSAK1_07599A6D3J71
Predicted hydrolaseyghYX SSON_3144Q3YXN41
Predicted hydrolaseVSAK1_05425A6D5M91
Predicted hydrolaseVSAK1_12340A6D6V91
Predicted hydrolase of alkaline phosphatase superfamily proteinVSAK1_16852A6CUT11
Predicted hydrolase of the HAD superfamily proteinVSAK1_03705A6D3S91
Predicted inner membrane peptidase (Fragment)VSAK1_26815A6D7W11
Predicted membrane proteinVS_3040B7VMC71
Predicted membrane proteinVSAK1_12005A6D2X71
Predicted NAD/FAD-dependent oxidoreductaseFTN_1621A0Q8B51
Predicted oxidoreductaseVSAK1_15432A6D7171
Predicted periplasmic lipoproteinVS_1921B7VGQ41
Predicted periplasmic or secreted lipoproteinVS_0436B7VIZ01
Predicted permease (Fragment)VSAK1_03600A6D3Q81
Predicted Rossmann fold nucleotide-binding protein (Fragment)VSAK1_10588A6D8T51
Predicted transcriptional regulatorVSAK1_22729A6CVV21
Prephenate dehydratase (PDT) (EC 4.2.1.51)pheA FTT_0575Q5NH931
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