EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protease III (EC 3.4.24.55)ptr YPO1019Q7CH001
Protease PfpIpfpI PA0355Q9I6D81
Protease, insulinase family/protease, insulinase familyVC_0554Q9KUG71
Protease, membrane-associatedyibP KPN_03958A6TFK91
Proteasome subunit alpha (EC 3.4.25.1) (20S proteasome alpha subunit) (Proteasome core protein PrcA)prcA Rv2109cP9WHU11
Proteasome subunit beta (EC 3.4.25.1) (20S proteasome beta subunit) (Proteasome core protein PrcB)prcB Rv2110cP9WHT91
Protein ClpV1clpV1 PA0090Q9I7421
Protein CreA (Catabolite regulation protein A)creA STM4587Q7CP641
Protein CsuAABAYE1320B0V7M31
Protein CsuA/B putative secreted protein related to type I piliABAYE1319B0V7M21
Protein CsuB putative secreted protein related to type I piliABAYE1321B0V7M41
Protein DedA (Protein DSG-1)dedA b2317 JW2314P0ABP61
Protein deglycase 1 (EC 3.1.2.-) (EC 3.5.1.124) (Glyoxalase III) (EC 4.2.1.130) (Holding molecular chaperone) (Hsp31)hchA yedU yzzC b1967 JW1950P316581
Protein DltDdltD SAOUHSC_00872Q2FZW31
Protein DltDLMRG_02070A0A0H3GAT91
Protein ElaBelaB yfbD b2266 JW2261P0AEH51
Protein F-related proteinVSAK1_15362A6D7031
Protein FhaEfhaE fimD BP1883Q008791
Protein FixCfixC yaaS b0043 JW0042P686441
Protein FtsNB195_02583M5QZM51
Protein GltLB195_11246M5QHD41
Protein GrpE (HSP-70 cofactor)grpE Fphi_1402B0TYF11
Protein GrpE (HSP-70 cofactor)grpE B195_04322M5QNQ51
Protein GrpE (HSP-70 cofactor)grpE spr0454Q8CWT41
Protein GrpE (HSP-70 cofactor)grpEQ8L3991
Protein GrpE (HSP-70 cofactor)grpE ACL_0549A9NFN71
Protein GrpE (HSP-70 cofactor)grpE Rv0351 MTCY13E10.11P9WMT51
Protein GrpE (HSP-70 cofactor)grpE SPy_1761 M5005_Spy1499P688921
Protein HemYhemY b3802 JW3774P0ACB71
Protein HflCSC1083_0408G4A6G81
Protein HflCSmlt3595B2FQG31
Protein HflCOOM_1330I2AZZ51
Protein HflChflC SCH_4240Q57GL61
Protein HflChflC FTT_0634Q5NH371
Protein HflKhflK SCH_4239Q57GL71
Protein HflKhflK FTT_0633Q5NH381
Protein IpgBipgB CP0130P335481
Protein kinaseAC1_2162B1R8F91
Protein kinase (EC 2.7.11.1)yeaG PP_0397Q88QU01
Protein MvaTB195_10121M5QGQ41
Protein MxiCmxiC CP0146Q046401
Protein NirFnirF PA0516Q514801
Protein of uncharacterised function (DUF3186)SAMEA3375004_00125A0A160WYR61
Protein of uncharacterised function (DUF3798) (Putative lipoprotein)BN1095_250021 BN1096_680020 BN1097_690010 SAMEA3375004_04156 SAMEA3375059_00025A0A069AK171
Protein PhnAphnA yjdM b4108 JW4069P0AFJ11
Protein phosphatase CheZ (EC 3.1.3.-) (Chemotaxis protein CheZ)cheZ PA1457Q514341
Protein phosphatase CheZ (EC 3.1.3.-) (Chemotaxis protein CheZ)VSAK1_03139A6CXC01
Protein PrgIprgI STM2873P417841
Protein rarDKW89_2307A0A0K2DZM21
Protein RecA (Recombinase A)recA jhp_0141Q9ZMS71
Protein RecA (Recombinase A)recA KPN78578_29710 KPN_03031A6TCW11
Protein RecA (Recombinase A)recA FTN_0122A0Q4681
Protein RecA (Recombinase A)recA Cj1673cQ0P7V61
Protein RecA (Recombinase A)recA B195_10806M5QUQ31
Protein RecA (Recombinase A)recA PP_1629Q88ME41
Protein RecA (Recombinase A)recA HPSD74_1181U4SHB41
Protein RecA (Recombinase A)recA SPy_2116 M5005_Spy1799P0C0951
Protein RecA (Recombinase A)recA CD630_13280Q18BJ41
Protein RecA (Recombinase A)recA Smlt1741B2FL311
Protein RecA (Recombinase A)recA SCH_2762Q57KU41
Protein RecA (Recombinase A)recA SAOUHSC_01262Q2FZ091
Protein RecA (Recombinase A)recA LMRG_00850G2JZ141
Protein rep (Replication protein)rep SPD_2300O527761
Protein Rv1269cRv1269c MTCY50.13P9WM451
Protein SanAsanA yeiF b2144 JW2132P0AFY21
Protein Smg homologsmg VSAK1_24385A6D3X41
Protein SopA (Plasmid partition protein A)sopA A ECOK12F046P625561
Protein TolAtolA HPSD74_0018U4SP581
Protein TolBtolB MXAN_5756Q1D0D01
Protein TolBtolB jhp_1055Q9ZK861
Protein TolBtolB KPN_00744A6T6G61
Protein TolBtolB ABSDF0908B0VT821
Protein TolBtolB B195_07300M5QKD11
Protein TolBtolB VC_1836Q9KR111
Protein TolBtolB VS_1116B7VMJ21
Protein TolBtolB YPO1124 y3055 YP_1032Q8ZGZ11
Protein TolBtolB SF0557 S0570Q83MM71
Protein TolBtolB J804_0074A0A014EKM21
Protein TolBtolB SC1083_1318G4A9121
Protein TolBtolB NSU_1019G6E9J81
Protein TolBtolB OOM_0338I2AXI51
Protein TolQSC1083_1315G4A9091
Protein TolQtolQ HPSD74_0016U4SM551
Protein TonBtonB NMB1730P570041
Protein TonBSmlt4506B2FMI91
Protein TonBtonB exbA b1252 JW5195P029291
Protein translocase subunit SecAsecA KPN78578_01010 KPN_00102A6T4P11
Protein translocase subunit SecAsecA CPC_2474B1BKC41
Protein translocase subunit SecAsecA SPJ_1595C1CFS11
Protein translocase subunit SecAsecA div+ BSU35300P283661
Protein translocase subunit SecAsecA SC1083_0071G4A5I61
Protein translocase subunit SecAsecA azi pea prlD b0098 JW0096P104081
Protein translocase subunit SecAsecA SSON_0106Q3Z5R11
Protein translocase subunit SecAsecA SPy_1805 M5005_Spy1534Q99Y961
Protein translocase subunit SecAsecA KW89_3048A0A0K2E1P21
Protein translocase subunit SecAsecA FTT_0769Q5NGR31
Protein translocase subunit SecA 1secA1 SAOUHSC_00769O064461
Protein translocase subunit SecA 2secA2 SAOUHSC_02985Q2FUW61
Protein translocase subunit SecA 2secA2 LMRG_00265G2K3V61
Protein translocase subunit SecDsecD MBMO_EB0-39H12.0040A4GHV31
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