EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Protein translocase subunit SecDsecD NMB0607Q9K0J01
Protein translocase subunit SecDsecD SC1083_1367G4A9591
Protein translocase subunit SecDsecD HPSD74_1449U4SI451
Protein translocase subunit SecDsecD VSAK1_14292A6D7521
Protein translocase subunit SecDsecD OOM_1306I2AZX31
Protein translocase subunit SecDsecD SCH_0449Q9ZFF81
Protein translocase subunit SecDsecD FTT_1115cQ5NFV31
Protein translocase subunit SecEsecE MXAN_3071Q1D7U91
Protein translocase subunit SecGSAOUHSC_00801Q2G0261
Protein translocase subunit SecYsecY MXAN_3319Q1D7551
Protein translocase subunit SecYsecY CPC_2730B1BMJ81
Protein translocase subunit SecYsecY PP_0474Q88QL51
Protein translocase subunit SecYsecY SPy_0073Q9A1V41
Protein translocase subunit SecYsecY OOM_0241I2AX991
Protein translocase subunit SecYsecY SAOUHSC_02491O083871
Protein translocase subunit SecYsecY FTT_0345Q5NHU81
Protein translocase subunit SecYsecY LMRG_02156A0A0H3GKN51
Protein YchQ (Protein SirB2)ychQ sirB2 b1213 JW1204Q467551
Protein YdePydeP b1501 JW1495P775611
Protein YebFyebF SSON_1301Q3Z2J81
Protein YgiWygiW b3024 JW2992P0ADU51
Protein-export membrane protein SecFsecF PP_0836Q88PL41
Protein-export membrane protein SecFsecF Smlt2012B2FN031
Protein-export membrane protein SecFsecF OOM_1307I2AZX41
Protein-export membrane protein SecFsecF FTT_1114cQ5NFV41
Protein-export protein SecBsecB Fphi_1132B0TX981
Protein-export protein SecBsecB Fphi_0705B0TW181
Protein-export protein SecBsecB PP_5053Q88CX71
Protein-export protein SecBsecB YPO0067 y0074 YP_0067Q8ZJM71
Protein-export protein SecBsecB Smlt0171B2FHD71
Protein-export protein SecB (Chaperone SecB)secB b3609 JW3584P0AG861
Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77)OOM_0501I2AXY01
Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) (L-isoaspartyl protein carboxyl methyltransferase) (Protein L-isoaspartyl methyltransferase) (Protein-beta-aspartate methyltransferase) (PIMT)pcm PA3624P456831
Protein-methionine-sulfoxide reductase catalytic subunit MsrP (EC 1.8.5.-)msrP YPO3662 y0205 YP_3884Q8ZAW91
Protein-methionine-sulfoxide reductase catalytic subunit MsrP (EC 1.8.5.-)msrP SSON_2030Q3Z0L81
Protocatechuate 3,4-dioxygenase (Protocatechuate 3,4-dioxygenase beta chain) (EC 1.13.11.3) (Protocatechuate 3,4-dioxygenase subunit beta) (Protocatechuate 3,4-dioxygenase, beta subunit)pcaH A7M79_10725 A7M90_02565 A7N09_17425 AB895_3724 AB988_3712 APD06_19700 AZE33_11005 IX87_20885 LV38_03102A0A059ZBE21
Protocatechuate 3,4-dioxygenase subunit betaB195_12791M5QZ921
Proton-dependent oligopeptide transport (POT) family proteinFTT_0953cQ5NG991
Proton-dependent oligopeptide transport (POT) family proteinFTT_1253Q5NFI11
Proton-dependent oligopeptide transporter (POT) family protein, di-or tripeptide:H+ symporterFTN_1272A0Q7D81
Proton-translocating NADH-quinone oxidoreductase, chain L family protein (EC 1.6.5.3)KU39_2922A0A0K2L7P41
Proton/glutamate symporterVSAK1_25645A6D2P11
Proton/glutamate-aspartate symporter (Glutamate-aspartate carrier protein) (Proton-glutamate-aspartate transport protein)gltP b4077 JW4038P213451
Proton/peptide symporter family proteinMXAN_2608Q1D9461
Pseudouridine synthase (EC 5.4.99.-)SP70585_0739C1C6421
Pseudouridine synthase (EC 5.4.99.-)rluD spr0830Q8DQ631
Pseudouridine synthase (EC 5.4.99.-)ymfC SSON_1153Q3Z2Y41
Pseudouridine synthase (EC 5.4.99.-)HPSD74_1884U4SC681
Pseudouridine synthase (EC 5.4.99.-)SPy_0827Q9A0D11
Pseudouridine synthase (EC 5.4.99.-)SPy_1127Q99ZQ61
Pseudouridine synthase (EC 5.4.99.-)SPy_0369Q9A1B01
Pseudouridine synthase (EC 5.4.99.-)OOM_0979I2AZ461
Pseudouridine-5'-phosphate glycosidase (PsiMP glycosidase) (EC 4.2.1.70)psuG VSAK1_01367A6D2F91
PspA (Fragment)pspAQ9L5781
PTS enzyme IIC, mannose-specificmanY SSON_1342Q3Z2F91
PTS system EIIBC component SAOUHSC_00158 [Includes: Phosphotransferase enzyme IIB component (EC 2.7.1.-) (PTS system EIIB component); Permease IIC component (PTS system EIIC component)]SAOUHSC_00158Q2G1G51
PTS system fructose-specific EIIABC component (EIIABC-Fru) [Includes: PTS system fructose-specific EIIA component (EC 2.7.1.202) (EII-Fru) (Fructose-specific phosphotransferase enzyme IIA component); PTS system fructose-specific EIIB component (EC 2.7.1.202) (EIII-Fru) (Fructose-specific phosphotransferase enzyme IIB component); PTS system fructose-specific EIIC component (Fructose permease IIC component)]fruA BSU14400P710121
PTS system galactitol-specific EIIA component (EIIB-Gat) (Galactitol-specific phosphotransferase enzyme IIA component) (EC 2.7.1.200)gatA b2094 JW2078/JW2081P698281
PTS system glucose-specific EIIA component (EIIA-Glc) (EIII-Glc) (Glucose-specific phosphotransferase enzyme IIA component) (EC 2.7.1.199)crr gsr iex tgs treD b2417 JW2410P697831
PTS system glucose-specific EIICBA component (EC 2.7.1.199) (EIICBA-Glc) (EII-Glc) (EIICBA-Glc 1) [Includes: Glucose permease IIC component (PTS system glucose-specific EIIC component); Glucose-specific phosphotransferase enzyme IIB component (PTS system glucose-specific EIIB component); Glucose-specific phosphotransferase enzyme IIA component (PTS system glucose-specific EIIA component)]ptsG glcA SAOUHSC_00155Q2G1G81
PTS system glucoside-specific EIICBA component [Includes: Glucoside permease IIC component (PTS system glucoside-specific EIIC component); Glucoside-specific phosphotransferase enzyme IIB component (EC 2.7.1.-) (PTS system glucoside-specific EIIB component); Glucoside-specific phosphotransferase enzyme IIA component (PTS system glucoside-specific EIIA component)]glcB SAOUHSC_02848Q2FV871
PTS system mannose-specific EIIAB componentSC1083_1523G4A9K91
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]manX SF1411 S1526P698001
PTS system mannose-specific EIIAB component (EC 2.7.1.191) (EIIAB-Man) (EIII-Man) [Includes: Mannose-specific phosphotransferase enzyme IIA component (PTS system mannose-specific EIIA component); Mannose-specific phosphotransferase enzyme IIB component (PTS system mannose-specific EIIB component)]manX gptB ptsL b1817 JW1806P697971
PTS system mannose-specific EIID component (EII-M-Man) (EIID-Man) (Mannose permease IID component)manZ Z2862 ECs2529P698071
PTS system N-acetylglucosamine-specific EIICBA component (EIICBA-Nag) (EII-Nag) [Includes: N-acetylglucosamine permease IIC component (PTS system N-acetylglucosamine-specific EIIC component); N-acetylglucosamine-specific phosphotransferase enzyme IIB component (EC 2.7.1.193) (PTS system N-acetylglucosamine-specific EIIB component); N-acetylglucosamine-specific phosphotransferase enzyme IIA component (PTS system N-acetylglucosamine-specific EIIA component)]nagE pstN b0679 JW0665P093231
PTS system, fructose-specific IIABC component, putativeSAOUHSC_02975Q2FUX01
PTS system, fructose-specific, IIABC component (EC 2.7.1.69)fruA AC3_0692B1BWK71
PTS system, glucose-like IIA componentCD630_31030Q184U01
PTS system, glucose-specific IIA component (EC 2.7.1.69)crr YPO2995Q7CJF81
PTS system, glucose-specific IIA component (EC 2.7.1.69)crr NTHI2020Q4QJN21
PTS system, glucose-specific IIBC component, putative (EC 2.7.1.69)SAOUHSC_00209Q2G2191
PTS system, IID componentCPC_1698B1BN461
Pts system, lactose-specific IIBC component, putativeSAOUHSC_02450Q2G2D41
PTS system, mannitol-specific component, putativeSAOUHSC_02400Q2FW991
PTS system, mannose-specific IIAB componentVSAK1_10688A6D1Y51
PTS system, mannose/fructose/sorbose family, IIC componentAC1_0972B1R4M11
PTS system, N-acetylglucosamine-specific IIABC componentVSAK1_10638A6D1X51
PTS system, N-acetylglucosamine-specific IIBC component (EC 2.7.1.69)nagE CPC_0100B1BFR51
PTS system, sucrose-specific IIBC component (EC 2.7.1.69)CJD_2097B1V1331
PTS system, trehalose-specific IIBC component (EC 2.7.1.69)treB CPC_0573B1BH161
Pur operon repressorSAOUHSC_00467Q2G0S71
Purine nucleoside phosphorylase (EC 2.4.2.1) (Inosine-guanosine phosphorylase)punA SPy_0892Q9A0821
Purine nucleoside phosphorylase DeoD-type (PNP) (EC 2.4.2.1)deoD STM4570Q8ZJV71
Purine nucleoside phosphorylase DeoD-type (PNP) (EC 2.4.2.1)deoD MXAN_2306Q1D9Z71
Purine nucleoside phosphorylase DeoD-type (PNP) (EC 2.4.2.1)deoD KPR_0918R4Y5N11
Purine nucleoside phosphorylase DeoD-type (PNP) (EC 2.4.2.1)deoD SSON_4535Q3YU091
Purine nucleoside phosphorylase DeoD-type (PNP) (EC 2.4.2.1)deoD2 deoD SPy_0894Q9A0811
Purine nucleoside phosphorylase DeoD-type (PNP) (EC 2.4.2.1) (Inosine phosphorylase)deoD pup b4384 JW4347P0ABP81
Purine-nucleoside phosphorylase (EC 2.4.2.1)Fphi_0152B0TYK81
Purine-nucleoside phosphorylase (EC 2.4.2.1)deoD FTN_0669A0Q5P61
Putativejhp_1206Q9ZJU21
Putativejhp_1470Q9ZJ461
Putativejhp_1453Q9ZJ621
Putativejhp_1413Q9ZJA01
Putativejhp_1382Q9ZJD01
Putativejhp_1356Q9ZJF61
Putativejhp_1350Q9ZJG21
Putativejhp_1347Q9ZJG41
Putativejhp_1157Q9ZJZ01
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