EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Putative competence-damage inducible proteincinA SPy_2117 M5005_Spy1800Q99XP11
Putative copper homeostasis lipoproteincutF YPO1067Q7CH241
Putative copper resistance protein DYPO1785Q7CHW91
Putative coproporphyrinogen III oxidase (EC 1.3.3.3)hemN SPy_1040Q99ZW61
Putative cyanophycin synthetase (EC 6.3.2.29) (EC 6.3.2.30)OOM_1291I2AZW21
Putative cyclomaltodextrinase (EC 3.2.1.-)amyB SPy_1304Q99ZB21
Putative cystathionine beta-synthaseMXAN_2041Q1DAQ31
Putative cystathionine beta-synthase Rv1077 (EC 4.2.1.22) (Beta-thionase) (Serine sulfhydrase)cbs Rv1077P9WP511
Putative cystine-binding periplasmic proteinfliY YPO1846Q7CI031
Putative cytochrome cMXAN_5402Q1D1C41
Putative cytochrome cSmlt2031B2FN181
Putative cytochrome C biogenesis proteinCj1013cQ0P9N91
Putative CYTOCHROME C PEROXIDASEjhp_1354Q9ZJF81
Putative cytochrome c-type biogenesis proteinVSAK1_03209A6CXD41
Putative cytoplasmic membrane proteinlemA SPy_0330Q9A1D61
Putative cytoplasmic proteinKPN_pKPN4p07048A6TIK51
Putative cytoplasmic proteinSTM1078Q7CQT11
Putative D-3-phosphoglycerate dehydrogenaseFSU_2951C9RL301
Putative D-alanine transferase DltDdltD CD630_28540Q183U11
Putative D-amino acid dehydrogenase small subunitSmlt3457B2FP271
Putative deacetylaseKPN_00530A6T5V91
Putative dehydrogenaseyliI SSON_0820Q3Z3U71
Putative dehydrogenease / oxidoreductaseSPy_0440Q9A1661
Putative DEOR-type transcriptional regulatorVSAK1_23459A6CW981
Putative deoxyguanosine kinase/deoxyadenosine kinase(I) subunit (EC 2.7.1.113)SPy_0121Q9A1S51
Putative deoxyribodipyrimidine photolyase (EC 4.1.99.3)phr SPy_1505Q99YX01
Putative dextran glucosidasedexS SPy_2096Q99XQ51
Putative diacylated glycolipid transporter LprF (Lipoprotein LprF)lprF Rv1368 MTCY02B12.02P9WK471
Putative diacylglycerol kinaseVSAK1_05430A6D5N01
Putative dihydrofolate reductasedyr SPy_0883Q9A0911
Putative dihydroorotate dehydrogenase A (fumarate) (DHOD A) (DHODase A) (DHOdehase A) (EC 1.3.98.1)pyrD SPy_1432 M5005_Spy1165Q99Z281
Putative dihydroxyacetone kinase, C-terminal domaindhaL KPN_03496A6TEA71
Putative dipeptidaseAC1_1614B1R5R31
Putative dipeptidaseSPy_1070Q99ZU11
Putative dipeptidaseSmlt4686B2FP981
Putative divalent cation transport proteinSPy_1827Q99Y831
Putative DNA binding regulatory protein-lantibiotic associatedsrtR SPy_1081Q7DAL91
Putative DNA methyltransferase YeeA (EC 2.1.1.-) (Modification methylase BsuMORF677P) (M.BsuMORF677P)yeeA BSU06760O315041
Putative DNA polymerase III delta' subunitSPy_0400Q9A1891
Putative DNA-binding protein HU-betahupB Smlt0992B2FQR51
Putative DNA/pantothenate metabolism flavoproteindfp SPy_1222Q99ZI01
Putative drug-resistance cell envelope-related proteinsmeP Smlt3924B2FTS11
Putative dTDP-4-keto-6-deoxyglucose-3,5-epimerasecpsFP SPy_0935Q9A0461
Putative dTDP-4-keto-L-rhamnose reductasermlD SPy_0784Q9A0G61
Putative efflux system component YknXyknX BSU14350O317101
Putative efflux transporterPP_0179Q88RF11
Putative Efflux transporterPP_3789Q88GD51
Putative electron transfer flavoprotein subunit betaetfS Smlt0646B2FMP61
Putative electron transport protein YccMyccM b0992 JW0977P526361
Putative endo-1,4-beta-glucanaseFSU_3149C9RMD21
Putative endo-1,4-beta-xylanaseFSU_2262D9S4301
Putative endo-1,4-beta-xylanaseFSU_2263C9RS201
Putative endo-1,4-beta-xylanaseFSU_2264C9RS211
Putative endo-beta-N-acetylglucosaminidase (EC 3.2.1.96) (Murein hydrolase)lytB spr0867P592061
Putative endoglucanaseFSU_1947D9SBI11
Putative endoglucanaseFSU_1893C9RR371
Putative endolysin, phage associatedSPy_0601Q9A0V21
Putative ENDONUCLEASEjhp_0306Q9ZMB51
Putative endopeptidaseNSU_2478G6EDQ71
Putative endoribonuclease L-PSPMXAN_3205Q1D7G71
Putative endoribonuclease L-PSPCj1388Q0P8M11
Putative enoyl CoA hydratase (EC 4.2.1.17)phaB SPy_1758Q99YD01
Putative enoyl-CoA hydratasee (EC 4.2.1.17)Smlt3556B2FQC81
Putative entericidin BecnB STM4336Q7CP991
Putative enzymeycfS KPN_01111A6T7H31
Putative esteraseMXAN_6056Q1CZI21
Putative esteraseMXAN_4392Q1D4581
Putative esteraseSPy_1718Q99YG31
Putative esteraseSPy_1850Q99Y641
Putative esteraseSPy_1308Q99ZB01
Putative Exopolysaccharide transport proteinPP_3127Q88I741
Putative exotoxin (Superantigen)speJ SPy_0436Q99QN11
Putative exported lipoproteinSmlt4560B2FNA41
Putative exported oligoPEPTIDASE (EC 3.4.-.-)Smlt4084B2FHW11
Putative exported peptidase (EC 3.4.14.-)Smlt1246B2FTA31
Putative exported proteinYPO0102Q0WKJ61
Putative exported proteinYPO0800Q74S031
Putative exported proteinYPO1997Q7CI921
Putative exported proteinYPO2305Q7CII81
Putative exported proteinygiW YPO3027Q7CJH61
Putative exported proteinYPO3528Q0WBC11
Putative exported proteinYPO3551Q74PT11
Putative exported proteinyrbC YPO3572Q7CL911
Putative exported proteinYPO3699Q7CL831
Putative exported tail-specific protease (EC 3.4.21.102)Smlt4045B2FUS71
Putative extramembranal proteindltD SPy_1309Q99ZA91
Putative ferredoxin/flavodoxin oxidoreductase,alpha subunit (EC 1.2.7.-)CD630_01160Q18CK81
Putative ferredoxin/flavodoxin oxidoreductase,beta subunit (EC 1.2.7.-)CD630_01170Q18CK71
Putative ferric siderophore receptor (TonB-dependent siderophore receptor)iutA S4052 SF3719 AJR25_020100A0A0H2V2V11
Putative ferric siderophore receptor proteinABAYE1984B0VDW11
Putative ferrioxamine receptorKPN_02304A6TAV91
Putative fibronectin-binding proteinlmo0721Q8Y9211
Putative fibronectin-binding protein-like protein Afbp SPy_1013Q99ZY71
Putative flagellar hook-associated proteinSmlt2307B2FQU81
Putative flagellar hook-associated proteinSmlt2308B2FQU91
Putative flagellar motor proton channelmotA Cj0337cQ0PBH21
Putative flagellin YvzByvzB BSU35150O343661
Putative flavodoxinSPy_0721Q9A0L41
Putative flavoproteindpfB SPy_1221Q99ZI11
Putative Flp pilus assembly proteinVSAK1_05905A6CZH11
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