EVpedia provide top 100+ EV markers, selected according to their identification number.
Based on EV proteomes, we defined the identification number of protein A as the number of datasets which contain protein A.
Therefore, proteins with higher identification numbers were more conserved.

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Protein name Gene symbol UniProt accession Identification number
Putative oxidoreductaseSAVERM_4117Q82FY51
Putative oxidoreductaseVSAK1_23469A6CWA01
Putative oxidoreductaseVSAK1_21034A6CYI41
Putative oxidoreductaseVSAK1_24910A6CZ381
Putative oxidoreductaseVSAK1_25155A6CZ871
Putative oxidoreductaseSPy_1640Q99YL91
Putative oxidoreductaseSPy_0932Q9A0481
Putative oxidoreductaseSPy_2107Q99XP81
Putative oxidoreductaseSPy_0925Q9A0551
Putative oxidoreductaseCj0807Q0PA831
Putative oxidoreductase iron/ascorbate family proteinVSAK1_24089A6D1M71
Putative oxidoreductase, major subunitSSON_1622Q3Z1P51
Putative oxidoreductase/transketolaseSmlt3207B2FLE11
Putative p-aminobenzoyl-glutamate transporterVSAK1_11855A6D2U71
Putative para-aminobenzoate synthase, component IMXAN_1590Q1DBY11
Putative para-aminobenzoate synthetase (EC 4.1.3.-)pabB SPy_1990Q99XW61
Putative PARALOG OF HpaAjhp_0971Q9ZKG51
Putative PAS domain containing signal-transduction sensor proteinCj1191cQ0P9651
Putative PBP 5 synthesis repressorpsr SPy_1350Q99Z851
Putative pectate lyaseFSU_0577C9RJS51
Putative pectinesteraseybhC SCH_0784Q57RH11
Putative penicillin binding protein (PonA)ABSDF0292B0VPG91
Putative penicillin-binding proteinAC1_2629B1R3M01
Putative penicillin-binding proteinmrcA Smlt3826B2FSH81
Putative peptidaseVS_II0771B7VS221
Putative PeptidasePP_1908Q88LM21
Putative peptidasepqqL SSON_1630Q3Z1N71
Putative peptidaseSmlt0203B2FHG81
Putative peptidase M23 family proteinCj0131Q0PC061
Putative peptidase M23 family proteinCj1235Q0P9211
Putative peptidase, S37 familyMXAN_2253Q1DA491
Putative peptidase, S8 (Subtilisin) familyMXAN_1967Q1DAX11
Putative peptide ABC-transport system periplasmic peptide-binding proteinCj1584cQ0P8441
Putative peptidoglycan branched peptide synthesis protein, alanine adding enzymemurN SPy_0615Q9A0U51
Putative peptidoglycan branched peptide synthesis protein, serine/alanine adding enzymemurM SPy_0616Q9A0U41
Putative peptidoglycan enzymepbpC SSON_2601Q3YZ331
Putative peptidoglycan hydrolase (EC 3.2.1.17)mur1.1 SPy_0856Q9A0A91
Putative peptidoglycan hydrolase (EC 3.2.1.17)mur1.2 SPy_0857Q9A0A81
Putative peptidoglycan-associated lipoproteinFSU_0604C9RJU71
Putative peptidyl-dipeptidase Dcp (Dipeptidyl carboxypeptidase) (EC 3.4.15.5)dcp Smlt0223B2FI431
Putative peptidyl-prolyl cis-trans isomeraseSmlt1483B2FHM51
Putative peptidyl-prolyl cis-trans isomerase jhp_0161 (PPIase jhp_0161) (EC 5.2.1.8) (Rotamase jhp_0161)jhp_0161Q9ZMQ71
Putative periplasmic binding proteinSTM1633Q8ZPA31
Putative periplasmic binding proteinYPO3633Q7CL481
Putative periplasmic binding proteinyjeP SSON_4344Q3YUI11
Putative periplasmic binding transport proteinfliY STM1954H9L4191
Putative periplasmic binding transport proteinyhdW SSON_3409Q3YWY21
Putative periplasmic cytochrome CCj1153Q0P9A31
Putative periplasmic immunogenic proteinyggE STM3065Q7CPU81
Putative periplasmic murein peptide-binding proteinmppA YPO2339Q7CIQ01
Putative periplasmic phosphate binding proteinpstS Cj0613Q0PAQ41
Putative periplasmic proteinyraP KPN_03558A6TEG91
Putative periplasmic proteinCj0530Q0PAY61
Putative periplasmic proteinCj0944cQ0P9V51
Putative periplasmic proteinCj0093Q0PC441
Putative periplasmic proteinCj0694Q0PAI51
Putative periplasmic proteinyggN STM3107Q8ZM421
Putative periplasmic proteinVSAK1_12160A6D8641
Putative periplasmic proteinydgA SCH_1483Q57PH21
Putative periplasmic proteinydgH SCH_1496Q57PF91
Putative periplasmic proteinCj0561cQ0PAV51
Putative periplasmic protein involved in capsular polysaccharide export (Wza)VS_0213B7VHN21
Putative periplasmic serine endoprotease DegP-like (EC 3.4.21.107)PP_1430Q88MY81
Putative periplasmic solute-binding proteinYPO4111Q7CFN11
Putative periplasmic substrate-binding transport proteinYPO1310Q0WHA31
Putative permeaseVSAK1_08566A6D0961
Putative peroxide resistance proteindpr SPy_1531Q99YU71
Putative phage baseplate assembly proteinSmlt1049B2FRA81
Putative phage infection proteinAC1_3169B1R6A31
Putative phage infection proteinCPC_2980B1BEQ61
Putative phage proteinCD630_13690Q18BN81
Putative phage proteinCD630_13760Q18BP11
Putative phage proteinCD630_29260Q184B51
Putative phage tail fiber proteinCD630_13730Q18BN41
Putative phage tail proteinCD630_13660Q18BM61
Putative phage tail proteinSmlt1047B2FRA61
Putative Phage tail sheath proteinMXAN_4494Q1D3W01
Putative phage XkdM-like proteinCD630_13640Q18BM91
Putative phage XkdN-like proteinCD630_13650Q18BM81
Putative phage XkdP-like proteinCD630_13670Q18BP01
Putative phage XkdS-like proteinCD630_13700Q18BN71
Putative phage-associated proteinSP70585_0039C1C9M61
Putative phage-related proteinSmlt1866B2FM221
Putative phage-related proteinSmlt1058B2FRB71
Putative phosphate acetyltransferase (EC 2.3.1.8)pta Cj0688Q0PAJ11
Putative phosphoenolpyruvate synthase regulatory protein (PEP synthase regulatory protein) (PSRP) (EC 2.7.11.33) (EC 2.7.4.28) (Pyruvate, water dikinase regulatory protein)PA1769Q9I2X01
Putative phosphoglucomutasepgmA SPy_1224Q99ZH81
Putative phosphoglycerate mutaseSPy_0598Q9A0V51
Putative phosphoglycerate mutaseSPy_1766Q99YC41
Putative phospholipaseSmlt3218B2FLF21
Putative phospholipase A1 (EC 3.1.1.32) (EC 3.1.1.4) (Phosphatidylcholine 1-acylhydrolase)NMB0464Q9K0U71
Putative phosphomannomutase (EC 5.4.2.8)HPSD74_1215U4SHE11
Putative phosphomethylpyrimidine kinasethiD SPy_1900Q99Y291
Putative phosphonate-binding proteinMXAN_5978Q1CZR01
Putative phosphoprotein phosphatasepppL SPy_1626Q99YM91
Putative phosphotransacetylasepta SPy_1128Q99ZQ51
Putative phosphotransferase system (PTS), enzyme II component BSPy_1058Q99ZV31
Putative phosphotransferase system phosphohistidine-containing proteinptsH SPy_1373Q99Z651
Putative phospotransferase system (PTS), enzyme II component DSPy_1060Q99ZV11
Putative phospotransferase system (PTS), enzyme II, component CSPy_1059Q99ZV21
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